Prosecution Insights
Prosecution Insights
Technology area: Biotechnology & Pharmaceuticals
10 pending office actions • 6 art units • 10 examiners • 0 of 10 (0%) have an AI response strategy ready • 13 patents granted in the last 365 days
TWIST BIOSCIENCE Corporation maintains a portfolio with 10 pending office actions in the Biotechnology & Pharmaceuticals technology area. These matters are spread across 10 distinct examiners and 6 distinct art units. This number of examiners relative to the 10 pending office actions indicates a broad distribution of the workload, with the pending office actions being handled by different individuals. Such a decentralized structure suggests that the company is not facing a bottleneck with any single examiner.
The busiest examiner, PHAM, KHAI QUYNH TIEN, is responsible for 1 busiest examiner pending action. The presence of 6 distinct art units suggests that the company's technology is being reviewed across the specialized divisions within the biotechnology sector. Practitioners managing this portfolio must account for the diverse perspectives of the 10 distinct examiners, which requires a highly adaptable prosecution strategy to ensure consistency across the 6 distinct art units. Navigating these distinct examiners requires careful coordination of legal arguments.
Based on the USPTO statutory response window for each pending office action. 5 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 5 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 only | 1 (10%) |
| §101 + other | 1 (10%) |
| §103 only | 1 (10%) |
| §102 only | 2 (20%) |
| §112 only | 2 (20%) |
| Multi-statute (no §101) | 3 (30%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| PHAM, KHAI QUYNH TIEN | 1 | 0.0% | +0.0% |
| ZHANG, KAIJIANG | 1 | 77.1% | +34.4% |
| GIAMMONA, FRANCESCA FILIPPA | 1 | 37.5% | +57.4% |
| ALFANO, ALAN | 1 | — | — |
| BRISTOL, LYNN ANNE | 1 | 63.4% | +39.8% |
| LAFAVE, ELIZABETH ROSE | 1 | 62.5% | +45.4% |
| FLINDERS, JEREMY C | 1 | 63.5% | +16.7% |
| GROSS, CHRISTOPHER M | 1 | 63.5% | +40.2% |
| WOITACH, JOSEPH T | 1 | 49.9% | +28.3% |
| HANDY, DWAYNE K | 1 | 62.6% | +25.1% |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 6 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17715890 | LIBRARIES FOR MUTATIONAL ANALYSIS | FLINDERS, JEREMY C | 85d overdue |
| 17368697 | DEVICES AND METHODS FOR LIGHT-DIRECTED POLYMER SYNTHESIS | HANDY, DWAYNE K | 35d overdue |
| 18066953 | COMPOSITIONS AND METHODS FOR DETECTION OF VARIANTS | GIAMMONA, FRANCESCA FILIPPA | 7d |
| 18168528 | COMBINATORIAL DNA ASSEMBLY FOR MULTISPECIFIC ANTIBODIES | PHAM, KHAI QUYNH TIEN | — |
| 18067652 | DE NOVO SYNTHESIZED GENE LIBRARIES | ZHANG, KAIJIANG | — |
| 17547073 | SYSTEMS FOR POLYNUCLEOTIDE CONSTRUCT DESIGN, VISUALIZATION AND TRANSACTIONS TO MANUFACTURE THE SAME | WOITACH, JOSEPH T | — |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18056648 | CYTOKINE VARIANT ANTIBODIES AND METHODS OF USE | BRISTOL, LYNN ANNE | 113d overdue |
| 17715890 | LIBRARIES FOR MUTATIONAL ANALYSIS | FLINDERS, JEREMY C | 85d overdue |
| 17721680 | BARCODE-BASED NUCLEIC ACID SEQUENCE ASSEMBLY | LAFAVE, ELIZABETH ROSE | 49d overdue |
| 17368697 | DEVICES AND METHODS FOR LIGHT-DIRECTED POLYMER SYNTHESIS | HANDY, DWAYNE K | 35d overdue |
| 18066953 | COMPOSITIONS AND METHODS FOR DETECTION OF VARIANTS | GIAMMONA, FRANCESCA FILIPPA | 7d |
| 18067652 | DE NOVO SYNTHESIZED GENE LIBRARIES | ZHANG, KAIJIANG | — |
| 17702643 | VARIANT NUCLEIC ACID LIBRARIES FOR TIGIT | GROSS, CHRISTOPHER M | — |
| 17547073 | SYSTEMS FOR POLYNUCLEOTIDE CONSTRUCT DESIGN, VISUALIZATION AND TRANSACTIONS TO MANUFACTURE THE SAME | WOITACH, JOSEPH T | — |
| Art Unit | Apps |
|---|---|
| 1684 | 5 |
| 1681 | 1 |
| 1641 | 1 |
| 1643 | 1 |
| 1631 | 1 |
| 1798 | 1 |
| App # | Title | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|
| 18168528 | COMBINATORIAL DNA ASSEMBLY FOR MULTISPECIFIC ANTIBODIES | PHAM, KHAI QUYNH TIEN | 1684 | §103 | Final Rejection | — | Pending | Feb 13, 2023 |
| 18067652 | DE NOVO SYNTHESIZED GENE LIBRARIES | ZHANG, KAIJIANG | 1684 | §102§103 | Non-Final OA | — | Pending | Dec 16, 2022 |
| 18066953 | COMPOSITIONS AND METHODS FOR DETECTION OF VARIANTS | GIAMMONA, FRANCESCA FILIPPA | 1681 | §103§112 | Non-Final OA | 7d | Pending | Dec 15, 2022 |
| 18060296 | NEUROPILIN-1 VARIANT ANTIBODIES AND METHODS OF USE | ALFANO, ALAN | 1641 | §112 | Non-Final OA | — | Pending | Nov 30, 2022 |
| 18056648 | CYTOKINE VARIANT ANTIBODIES AND METHODS OF USE | BRISTOL, LYNN ANNE | 1643 | §112 | Final Rejection | 113d overdue | Pending | Nov 17, 2022 |
| 17721680 | BARCODE-BASED NUCLEIC ACID SEQUENCE ASSEMBLY | LAFAVE, ELIZABETH ROSE | 1684 | §102 | Final Rejection | 49d overdue | Pending | Apr 15, 2022 |
| 17715890 | LIBRARIES FOR MUTATIONAL ANALYSIS | FLINDERS, JEREMY C | 1684 | §101 | Final Rejection | 85d overdue | Pending | Apr 07, 2022 |
| 17702643 | VARIANT NUCLEIC ACID LIBRARIES FOR TIGIT | GROSS, CHRISTOPHER M | 1684 | §102 | Final Rejection | — | Pending | Mar 23, 2022 |
| 17547073 | SYSTEMS FOR POLYNUCLEOTIDE CONSTRUCT DESIGN, VISUALIZATION AND TRANSACTIONS TO MANUFACTURE THE SAME | WOITACH, JOSEPH T | 1631 | §101§112 | Non-Final OA | — | Pending | Dec 09, 2021 |
| 17368697 | DEVICES AND METHODS FOR LIGHT-DIRECTED POLYMER SYNTHESIS | HANDY, DWAYNE K | 1798 | §103§112 | Non-Final OA | 35d overdue | Pending | Jul 06, 2021 |
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