Prosecution Insights
Last updated: October 25, 2026

Umberg Zipser LLP

Technology area: Biotechnology & Pharmaceuticals

53 pending office actions • 34 clients • 51 examiners • 44 art units • 0 of 53 (0%) have an AI response strategy ready

Analysis

Umberg Zipser, LLP reports 53 pending office actions in Biotechnology & Pharmaceuticals and 1862 career applications. The pending docket is presented alongside a sizable reported application record, providing context for the firm’s active prosecution workload.

The resolved allowance rate is 80.57%, and the average is 3.28 office actions per allowance. The latter measure indicates repeated examination activity in resolved matters, while the allowance figure describes the reported rate at which those matters reached allowance.

This combination gives practitioners a basis for evaluating both scale and prosecution demands. The application total frames the historical portfolio, and the outcome measures can inform expectations about claim development, response cycles, and the work required to pursue allowance.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Quality Metrics (n=1862 apps, methodology: how we score firms)

80.6%
Allowance Rate
n=1862
+0.49σ
Allowance Rate (norm)
n=1862
3.3
OAs to Allowance
n=883
-0.31σ
OAs to Allow (norm)
n=883
929 days
Time to Allowance
n=883
+11.7pp
Interview Lift
n=1862
30.8%
RCE Rate
n=1862
4.0%
Appeal Rate
n=1862

Rejection Performance (% of received rejections ultimately overcome)

52.6%
§101 Overcome
n=211
68.2%
§102 Overcome
n=381
66.0%
§103 Overcome
n=676
71.1%
§112 Overcome
n=568

Specialization & Scale

A61K, A61P, C07K
Top CPC Subclasses
26%
Top-3 CPC Share
n=1862
4
Practitioners
n=1862
465.5
Apps / Practitioner
n=1862

Portfolio Summary

53
Total Pending OAs
30
Non-Final OAs
22
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 17 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

7
Overdue
1
Due this week
4
Due this month
4
Due in next 60 days
1
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 17 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (7)Due ≤ 7 days (1)Due ≤ 30 days (4)Due ≤ 60 days (4)Due later (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

27
Hard (51%)
21
Medium (40%)
5
Easy (9%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 only1 (2%)
§101 + other11 (21%)
§103 only15 (28%)
§102 only3 (6%)
§112 only3 (6%)
Double-patenting only2 (4%)
Double-patenting + other3 (6%)
Multi-statute (no §101)15 (28%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

33
Life Sciences
62% of docket
2
Information Tech
4% of docket
3
Communications
6% of docket
1
Semiconductors
2% of docket
12
Mechanical / Eng
23% of docket
2
Business / Other
4% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

530 h
Manual time on pending OAs
106 h
Time saved (low, 20%)
186 h
Time saved (mid, 35%)
4.6 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
LIU, GUOZHEN 2 48.1% +26.0%
ZEMAN, MARY K 2 58.9% +34.2%
ELENISTE, PIERRE PAUL 1 35.4% +31.1%
GODDARD, LAURA B 1 50.8% +13.6%
DUFFY, BRADLEY 1 54.4% +46.0%
HANSEN, JARED A 1 53.1% +48.0%
PAULS, JOHN A 1 49.0% +27.7%
PARK, SOO JIN 1 82.0% +17.2%
TAMIL, JESSICA KAVINI 1 39.4% +46.0%
ARANT, HARRY E 1 50.0% +21.4%

Quick Wins (1)

Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
19067041 Method For Predicting Volume Of Object Based On Whether Object In Container Changes PARK, SOO JIN —

Hard Cases (27)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18280778 Multi-Dose Container for Ophthalmic Compositions FAY, ZOHREH ALEMZADEH 119d overdue
18292702 Method And Device For Detecting Multi-Access Account By Using Similarity Degree Between Nicknames RENWICK, REGINALD A 31d overdue
18876659 Improvements In Or Relating To Data Integrity PUTTAIAH, ASHA 25d overdue
18782979 Arthroscopic Surgery System And Method LABRANCHE, BROOKE N 1d overdue
17850756 METHODS FOR FORECASTING CLINICAL COURSE OF DIFFUSE LARGE B-CELL LYMPHOMA USING RNA-BASED BIOMARKERS AND MACHINE LEARNING ALGORITHMS SMITH, JENNIFER JOY 9d
17767615 Detecting Homologous Recombination Deficiencies (HRD) in Clinical Samples LIN, JERRY 16d
19061787 Collapsible Container TAMIL, JESSICA KAVINI 27d
19047205 Compositions and Methods to Form a Thermally Conductive Sheath ARANT, HARRY E 34d

Interview Candidates (12)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
16222798 Systems and Methods For RNA Analysis In Functional Confirmation Of Cancer Mutations ZEMAN, MARY K 77d overdue
19061787 Collapsible Container TAMIL, JESSICA KAVINI 27d
19047205 Compositions and Methods to Form a Thermally Conductive Sheath ARANT, HARRY E 34d
19460222 STABLE COMPOSITIONS OF BUPIVACAINE HYDROCHLORIDE ELENISTE, PIERRE PAUL —
19454185 haNK Cetuximab Combinations And Methods GODDARD, LAURA B —
19447763 Albumin Bound Macromolecule Tri-Agonist Activating GLP 1/GIP/Glucagon Receptors And Methods Therefor DUFFY, BRADLEY —
19411048 Prismatic Battery Cell and Method of Making the Same HANSEN, JARED A —
19288633 Systems and Methods for Detecting and Documenting Cryogenic Therapy of a Patient PAULS, JOHN A —

Client Portfolio (34 clients)

Top Art Units

Art UnitApps
16864
16443
16422
16852
16221
16431
17231
36831
37331
37631

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
19460222 STABLE COMPOSITIONS OF BUPIVACAINE HYDROCHLORIDE Nevakar Injectables Inc. ELENISTE, PIERRE PAUL 1622 §103 Final Rejection — Pending Jan 26, 2026
19454185 haNK Cetuximab Combinations And Methods Nantcell, Inc. GODDARD, LAURA B 1642 DP Final Rejection — Pending Jan 20, 2026
19447763 Albumin Bound Macromolecule Tri-Agonist Activating GLP 1/GIP/Glucagon Receptors And Methods Therefor Albunext, LLC DUFFY, BRADLEY 1643 DP Non-Final OA — Pending Jan 13, 2026
19411048 Prismatic Battery Cell and Method of Making the Same Nantg Power, LLC HANSEN, JARED A 1723 §103 Final Rejection — Pending Dec 05, 2025
19288633 Systems and Methods for Detecting and Documenting Cryogenic Therapy of a Patient Katherine Bao-Shian Lee Md, Apc PAULS, JOHN A 3683 §101§103 Non-Final OA — Pending Aug 01, 2025
19067041 Method For Predicting Volume Of Object Based On Whether Object In Container Changes Nuvilabs Co., Ltd. PARK, SOO JIN §102 Non-Final OA — Pending Feb 28, 2025
19061787 Collapsible Container Clevermade, LLC TAMIL, JESSICA KAVINI 3733 §103§112 Final Rejection 27d Pending Feb 24, 2025
19047205 Compositions and Methods to Form a Thermally Conductive Sheath Xgs Energy, Inc. ARANT, HARRY E 3763 §102§103 Final Rejection 34d Pending Feb 06, 2025
19046406 Method For Predicting Volume Of Target Object Using Reference Object Nuvilabs Co., Ltd. RHIM, WOO CHUL 2676 §102§103 Non-Final OA — Pending Feb 05, 2025
18876659 Improvements In Or Relating To Data Integrity Tokencertify Limited PUTTAIAH, ASHA 3691 §101§103 Final Rejection 25d overdue Pending Dec 18, 2024
18868726 Surgical Assembly and System Alesi Surgical Limited OUYANG, BO 3794 §103 Non-Final OA — Pending Nov 22, 2024
18882219 Nant COVID Vaccine Cross Reactivity Immunitybio, Inc. WANG, RUIXUE 1672 §102§103§112Other Non-Final OA — Pending Sep 11, 2024
18820045 Methods And Systems For Producing Carbon-Neutral Fuels From Aragonite Calcean Minerals And Materials, LLC JEONG, YOUNGSUL 1772 §112Other Non-Final OA — Pending Aug 29, 2024
18782979 Arthroscopic Surgery System And Method Convergence Medical Pty Ltd. LABRANCHE, BROOKE N 3771 §102§103§112 Final Rejection 1d overdue Pending Jul 24, 2024
18769216 Targeted IL-12 Treatments and Methods to Stimulate haNK and NK92mi Cells Nantbio, Inc. DONOGHUE, BRITTNEY ERIN 1675 §102§103§112 Non-Final OA — Pending Jul 10, 2024
18715883 UV SYSTEM AND METHODS FOR GENERATING AN ALPHA CHANNEL The Invisible Pixel Inc. BOYLAN, JAMES T 2486 §103 Non-Final OA 15d overdue Pending Jun 03, 2024
18713607 NEW CRYSTAL FORM OF COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF E-Nitiate Biopharmaceuticals (Hangzhou) Co., Ltd. LEE, CHIHYI NMN §112 Non-Final OA — Pending May 24, 2024
18671662 Primary T-Cell Expansion Nantbio, Inc. BELYAVSKYI, MICHAIL A 1644 §103 Non-Final OA — Pending May 22, 2024
18710969 Optical Coupling Structure Ligentec SA CHU, CHRIS H 2874 §102§103 Final Rejection — Pending May 16, 2024
18643905 Monocarboxylic Acid Transporter 4 as a Biomarker for Hypoxia Driven Tumor Growth and Treatment Nantbio, Inc. WOOLWINE, SAMUEL C 1681 §103 Non-Final OA — Pending Apr 23, 2024
18609750 Oolitic Aragonite Beads and Methods Therefor Nant Holdings Ip, LLC ATKINSON, JOSHUA ALEXANDER 1612 §101§102§103§112DP Non-Final OA — Pending Mar 19, 2024
18693129 COMPOSITION AND COMPOSITE ARTICLE FOR FORMING NITRIC OXIDE Sterile State, Inc. CHEN, CHANGRU 1796 §102§103 Non-Final OA — Pending Mar 18, 2024
18606693 BIO-RESORBABLE ORTHOPAEDIC LAG SCREW FOR SMALL BONE FRACTURE FIXATION Biocomposites Limited COLEY, ZADE JAMES 3775 §102§103 Final Rejection — Pending Mar 15, 2024
18594178 Chlorthalidone Compositions And Methods Nivagen Pharmaceuticals, Inc. RAMOS LEWIS, JOSMALEN MILAGROS 1621 §103 Non-Final OA 40d Pending Mar 04, 2024
18292702 Method And Device For Detecting Multi-Access Account By Using Similarity Degree Between Nicknames Kakao Games Corp. RENWICK, REGINALD A 3715 §101 Final Rejection 31d overdue Pending Jan 26, 2024
18292864 Method And Device For User Information Prediction Using Play Log Kakao Games Corp. WASAFF, JOHN S. 3629 §101§102§103§112 Non-Final OA — Pending Jan 26, 2024
18573680 Method For Providing Dart Game And Dart Game Server Phoenixdarts Co., Ltd. VANDERVEEN, JEFFREY S 3711 §103 Final Rejection 15d Pending Dec 22, 2023
18509777 Compositions And Methods Of MAIT Cell Activation Immunitybio, Inc. PETRASH, HILARY ANN 1644 §102§103§112 Non-Final OA — Pending Nov 15, 2023
18497318 Method For Predicting Protein Binding Site Deargen Inc. ANDERSON-FEARS, KEENAN NEIL 1687 §101§103§112 Non-Final OA — Pending Oct 30, 2023
18555493 Organic Compound And Organic Light Emitting Device Including Same P&H Tech Co., Ltd. MOWLA, GOLAM 1721 §102 Non-Final OA — Pending Oct 13, 2023
18474797 Cancer Score for Assessment and Response Prediction from Biological Fluids Nantomics LLC LIU, GUOZHEN 1686 §101§103§112Other Non-Final OA — Pending Sep 26, 2023
18465868 Cancer Score for Assessment and Response Prediction from Biological Fluids Nantomics, LLC LIU, GUOZHEN 1686 §101§103§112 Non-Final OA — Pending Sep 12, 2023
18280778 Multi-Dose Container for Ophthalmic Compositions Vyluma Inc. FAY, ZOHREH ALEMZADEH 1617 §103§112 Non-Final OA 119d overdue Pending Sep 07, 2023
18272533 Devices and Methods for Providing Nitric Oxide Sterile State, Inc. TAI, XIUYU 1795 §102§112 Non-Final OA — Pending Jul 14, 2023
18272541 Devices and Methods for Detecting the Presence of Nitric Oxide Sterile State, Inc. EOM, ROBERT J 1797 §102 Non-Final OA — Pending Jul 14, 2023
18343065 Method For Change Detection Si Analytics Co., Ltd. LEE, BENEDICT E 2665 §103 Final Rejection — Pending Jun 28, 2023
18258925 Fc-Receptor CAR Constructs and Cells Immunitybio, Inc. MELCHIOR, JAMES RYLAND 1644 §103§112 Final Rejection 54d Pending Jun 22, 2023
18038934 Optical Device Having Monolithic Architecture And Method For Manufacturing Same Deep-In-Sight Co., Ltd. BAGHDASARYAN, HOVHANNES 3645 §103 Final Rejection 16d overdue Pending May 25, 2023
18043276 Genetic Construct Instituto De Medicina Molecular João Lobo Antunes MCCORMICK, CATHERINE LYNN 1638 §103 Final Rejection 40d Pending Feb 27, 2023
18164423 Gate Operator with Context Sensitive QR Code Intelligent Entry Machines LLC PAN, YONGJIA 2118 §103 Final Rejection — Pending Feb 03, 2023
17999087 T Cells Instituto De Medicina Molecular João Lobo Antunes WESTON, ALYSSA G 1633 §102§103§112 Non-Final OA — Pending Nov 17, 2022
17850756 METHODS FOR FORECASTING CLINICAL COURSE OF DIFFUSE LARGE B-CELL LYMPHOMA USING RNA-BASED BIOMARKERS AND MACHINE LEARNING ALGORITHMS Genomic Testing Cooperative, Lca SMITH, JENNIFER JOY 1685 §101§103§112 Final Rejection 9d Pending Jun 27, 2022
17739792 Systems, Methods, and Compositions for Viral-Associated Tumors Five3 Genomics, LLC ZEMAN, MARY K 1686 §101§102Other Non-Final OA — Pending May 09, 2022
17740040 High-Throughput Identification of Patient-Specific Neoepitopes as Therapeutic Targets for Cancer Immunotherapies Nant Holdings Ip, LLC WEHBE, ANNE MARIE SABRINA 1634 §103§112DP Non-Final OA — Pending May 09, 2022
17720624 Compositions and Methods for Targeted NGS Sequencing of cfRNA and cfTNA Genomic Testing Cooperative, Lca POHNERT, STEVEN C 1683 §101§103§112 Final Rejection — Pending Apr 14, 2022
17767615 Detecting Homologous Recombination Deficiencies (HRD) in Clinical Samples Immunitybio, Inc. LIN, JERRY 1685 §101§103 Final Rejection 16d Pending Apr 08, 2022
17697781 Techniques For Performing Subject Word Classification Of Document Data Tmaxtibero Co., Ltd. OPSASNICK, MICHAEL N 2658 §102§103 Non-Final OA 72d Pending Mar 17, 2022
17631844 Metal Recovery From Lead Containing Electrolytes Aqua Metals Inc. WILKINS III, HARRY D 1794 §103 Final Rejection — Pending Jan 31, 2022
17630075 ANTIBODY PRE-LOADED CD16+NK-92 CELLS AS AN EFFECTIVE THERAPEUTIC PRODUCT FOR TUMOR LYSIS Immunitybio, Inc. LU, CHENG 1642 §103§112DP Non-Final OA — Pending Jan 25, 2022
17270361 Neural Interface University Of Maribor PORTILLO, JAIRO H 3791 §103 Non-Final OA — Pending Feb 22, 2021

View all 53 →

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Frequently Asked Questions

What is Umberg Zipser LLP's patent allowance rate?

80.6% of resolved applications prosecuted by Umberg Zipser LLP were allowed, across 1,862 applications in USPTO records.

How many office actions does Umberg Zipser LLP average before allowance?

3.28 office actions per allowed application on average.

How many pending office actions does Umberg Zipser LLP have?

53 pending office actions as of October 2026, for 34 clients, before 51 examiners in 44 art units.

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