Prosecution Insights
Last updated: October 04, 2026

Cozen O'Connor (Alnylam)

Technology areas: Biotechnology & Pharmaceuticals • Chemistry & Materials

7 pending office actions • 3 clients • 6 examiners • 2 art units • 0 of 7 (0%) have an AI response strategy ready

Analysis

COZEN O'CONNOR (Alnylam) operates in the Biotechnology & Pharmaceuticals technology area, with 4 pending office actions currently active. This work is part of the firm's broader career history of 19375 applications. The 4 pending office actions represent the current focus for this specific set of files. The firm's experience in Biotechnology & Pharmaceuticals is supported by their 19375 career applications.

The firm maintains a resolved allowance rate of 85.65 percent, a figure calculated from their 19375 career applications. This 85.65 percent rate serves as a benchmark for the outcomes of their patent filings. Prosecution involves an average of 3.35 office actions per allowance, a metric that describes the typical interaction with patent examiners. For practitioners, this 3.35 average is a key indicator of the effort required to reach an allowance. The 4 pending office actions are managed alongside this 85.65 percent allowance rate and 3.35 office action average. These statistics provide a clear view of the firm's historical and current performance.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Quality Metrics (n=19375 apps, methodology: how we score firms)

85.6%
Allowance Rate
n=19375
+0.54σ
Allowance Rate (norm)
n=19375
3.4
OAs to Allowance
n=12754
-0.03σ
OAs to Allow (norm)
n=12754
1066 days
Time to Allowance
n=12754
+4.9pp
Interview Lift
n=19375
24.8%
RCE Rate
n=19375
2.2%
Appeal Rate
n=19375

Rejection Performance (% of received rejections ultimately overcome)

77.7%
§101 Overcome
n=1362
78.5%
§102 Overcome
n=5599
80.2%
§103 Overcome
n=8901
82.5%
§112 Overcome
n=5859

Specialization & Scale

H04W, G06F, H04L
Top CPC Subclasses
11%
Top-3 CPC Share
n=19375
0
Practitioners
n=19375
—
Apps / Practitioner
n=19375 (min 20)

Portfolio Summary

7
Total Pending OAs
4
Non-Final OAs
3
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 1 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

0
Overdue
0
Due this week
0
Due this month
1
Due in next 60 days
0
Due later

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

3
Hard (43%)
4
Medium (57%)
0
Easy (0%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§103 only3 (43%)
Double-patenting + other1 (14%)
Multi-statute (no §101)3 (43%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

3
Life Sciences
43% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
4
Business / Other
57% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

70 h
Manual time on pending OAs
14 h
Time saved (low, 20%)
24 h
Time saved (mid, 35%)
0.6 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
TRAN, CHRISTINA L 2 51.6% +48.2%
CHONG, JASON Y 1 73.3% +18.1%
CHO, DAVID H 1 31.9% +67.0%
ZAHORIK, AMANDA MARY 1 57.8% +49.0%
MONTGOMERY, STEPHEN EDWARD 1 — —
NGUYEN, KHANH TUAN 1 74.6% +18.7%

Hard Cases (3)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 3 ordered by deadline are shown.

App #TitleExaminerDue in
17611761 ORAL DELIVERY OF OLIGONUCLEOTIDES TRAN, CHRISTINA L 49d
18897206 PROCESS AND APPARATUS FOR CHEMICALLY TREATING A CARBON-CONTAINING FEEDSTOCK CHONG, JASON Y —
18394838 PROCESSES FOR PRODUCING AND REPROCESSING A RECYCLABLE ETHYLENE-VINYL ESTER POLYMER MONTGOMERY, STEPHEN EDWARD —

Interview Candidates (6)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 6 ordered by deadline are shown.

App #TitleExaminerDue in
17611761 ORAL DELIVERY OF OLIGONUCLEOTIDES TRAN, CHRISTINA L 49d
18897206 PROCESS AND APPARATUS FOR CHEMICALLY TREATING A CARBON-CONTAINING FEEDSTOCK CHONG, JASON Y —
18613537 3'-OH RNA-CONTAINING OLIGONUCLEOTIDE DEPROTECTION CHO, DAVID H —
18577377 BIS-RNAI COMPOUNDS FOR CNS DELIVERY ZAHORIK, AMANDA MARY —
18142234 INORGANIC SOLID PARTICLE COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF NGUYEN, KHANH TUAN —
18015202 Circular siRNAs TRAN, CHRISTINA L —

Client Portfolio (3 clients)

Top Art Units

Art UnitApps
16372
17611

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
18897206 PROCESS AND APPARATUS FOR CHEMICALLY TREATING A CARBON-CONTAINING FEEDSTOCK Braskem America, Inc. CHONG, JASON Y §102§103§112 Non-Final OA — Pending Sep 26, 2024
18613537 3'-OH RNA-CONTAINING OLIGONUCLEOTIDE DEPROTECTION Alnylam Pharmaceuticals, Inc. CHO, DAVID H §102§103§112DP Non-Final OA — Pending Mar 22, 2024
18577377 BIS-RNAI COMPOUNDS FOR CNS DELIVERY Alnylam Pharmaceuticals, Inc. ZAHORIK, AMANDA MARY §103 Non-Final OA — Pending Jan 08, 2024
18394838 PROCESSES FOR PRODUCING AND REPROCESSING A RECYCLABLE ETHYLENE-VINYL ESTER POLYMER Case Western Reserve University MONTGOMERY, STEPHEN EDWARD §103§112 Non-Final OA — Pending Dec 22, 2023
18142234 INORGANIC SOLID PARTICLE COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF Braskem America, Inc. NGUYEN, KHANH TUAN 1761 §103 Final Rejection — Pending May 02, 2023
18015202 Circular siRNAs Alnylam Pharmaceuticals, Inc. TRAN, CHRISTINA L 1637 §103 Final Rejection — Pending Jan 09, 2023
17611761 ORAL DELIVERY OF OLIGONUCLEOTIDES Alnylam Pharmaceuticals, Inc. TRAN, CHRISTINA L 1637 §103§112Other Final Rejection 49d Pending Nov 16, 2021

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