Prosecution Insights
Prosecution Insights
Technology areas: Biotechnology & Pharmaceuticals • Medical Devices & Mechanical Engineering
51 pending office actions • 32 art units • 50 examiners • 0 of 51 (0%) have an AI response strategy ready • 53 patents granted in the last 365 days
Case Western Reserve University is managing 52 pending office actions in the Biotechnology & Pharmaceuticals technology area. These 52 actions are assigned to 51 distinct examiners, indicating that almost every action has a unique reviewer. The portfolio is distributed across 32 distinct art units, showing significant technical diversity in biotech research. With 32 distinct art units involved, the university's pharmaceutical and biological innovations are being reviewed by a wide array of specialized groups across the 52 pending office actions.
The busiest examiner is MELHUS, BENJAMIN S, who is responsible for 2 pending office actions. The other actions are assigned to the remaining 51 distinct examiners. This means that 51 distinct examiners are providing input on the university's pending matters. For the practitioner, this distribution requires managing many different examiner personalities and art unit cultures. The breadth of 32 distinct art units ensures that the university's innovations are being evaluated by many different specialized teams. Having 2 pending office actions with MELHUS, BENJAMIN S represents the most concentrated point of contact.
Based on the USPTO statutory response window for each pending office action. 14 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 14 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 only | 1 (2%) |
| §101 + other | 7 (14%) |
| §103 only | 10 (20%) |
| §102 only | 1 (2%) |
| Double-patenting + other | 7 (14%) |
| Multi-statute (no §101) | 25 (49%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| MELHUS, BENJAMIN S | 2 | 60.4% | +44.1% |
| WONG, EDNA | 1 | 58.4% | -19.7% |
| KIM, KAITLYN EUNJI | 1 | 73.9% | +55.8% |
| SCHAETZLE, KENNEDY | 1 | 83.8% | +8.1% |
| KOWALKOWSKI, FIONA MARGARET | 1 | 100.0% | +0.0% |
| MORAN, EDWARD JOHN | 1 | 41.8% | +61.1% |
| TRUONG, QUANGLONG N | 1 | 78.8% | +23.6% |
| MORALES, JON ERIC C | 1 | 85.4% | +10.0% |
| LEVICKY, WILLIAM J | 1 | 69.4% | +29.7% |
| KATZ, DYLAN MICHAEL | 1 | 86.2% | +21.3% |
Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 2 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18901645 | SYSTEMS AND METHODS TO ESTIMATE FORCE OF AN INSTRUMENT | KATZ, DYLAN MICHAEL | 53d overdue |
| 18950244 | PATTERNED STIMULATION INTENSITY FOR NEURAL STIMULATION | MORALES, JON ERIC C | — |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 16630271 | COMPOSITIONS AND METHODS FOR TREATING MYELIN DISORDERS | AUDET, MAURY A | 112d overdue |
| 18546648 | SUBCUTANEOUS PHOTOBIOMODULATION | KUO, JONATHAN T | 51d overdue |
| 17331375 | BIOLOGICAL SAMPLING DEVICE AND METHOD OF USE | KREMER, MATTHEW | 30d overdue |
| 18517080 | COMPOSITIONS AND METHODS OF TREATING USHER SYNDROME III | NGUYEN, QUANG | 10d overdue |
| 18109406 | COMPOSITIONS AND METHODS OF REDUCING SERUM CHOLESTEROL AND PCSK9 | WELLS, LAUREN QUINLAN | 4d overdue |
| 17992994 | PREDICTING RECURRENCE IN EARLY STAGE NON-SMALL CELL LUNG CANCER (NSCLC) WITH INTEGRATED RADIOMIC AND PATHOMIC FEATURES | NASSER, ROBERT L | 30d |
| 17624347 | PRIMING MEDIA AND METHODS FOR STEM CELL CULTURE AND THERAPY | JOHNSON, ALLISON MARIE | 34d |
| 18337677 | SYSTEMS AND METHODS FOR STIMULATION PARAMETER CONTRAST (SPC) IMAGING | WELCH, WILLOW GRACE | 54d |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18901645 | SYSTEMS AND METHODS TO ESTIMATE FORCE OF AN INSTRUMENT | KATZ, DYLAN MICHAEL | 53d overdue |
| 19084469 | MAGNETIC RESONANCE-BASED CATHETER LOCALIZATION | KIM, KAITLYN EUNJI | — |
| 18878811 | SYNTHETIC SUPRACRESTAL DENTAL IMPLANT FIBERS | MORAN, EDWARD JOHN | — |
| 18967052 | MELT PROCESSED VIRAL NANOPARTICLE CONSTRUCTS | TRUONG, QUANGLONG N | — |
| 18950244 | PATTERNED STIMULATION INTENSITY FOR NEURAL STIMULATION | MORALES, JON ERIC C | — |
| 18914696 | VENTRAL SPINAL CORD STIMULATION FOR AT LEAST PARTIAL RESTORATION OF MOTOR FUNCTION | LEVICKY, WILLIAM J | — |
| 17855530 | BIOLOGICAL SAMPLING DEVICE AND METHOD OF USE | MELHUS, BENJAMIN S | — |
| 17855515 | BIOLOGICAL SAMPLING DEVICE AND METHOD OF USE | MELHUS, BENJAMIN S | — |
| Art Unit | Apps |
|---|---|
| 3792 | 3 |
| 3791 | 3 |
| 1653 | 2 |
| 1622 | 2 |
| 1658 | 2 |
| 1638 | 2 |
| 1795 | 1 |
| 3797 | 1 |
| 3772 | 1 |
| 3657 | 1 |
| App # | Title | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|
| 19222648 | SYSTEM AND METHOD FOR ELECTROCHEMICAL CO2 REDUCTION | WONG, EDNA | 1795 | §103§112 | Non-Final OA | — | Pending | May 29, 2025 |
| 19084469 | MAGNETIC RESONANCE-BASED CATHETER LOCALIZATION | KIM, KAITLYN EUNJI | 3797 | §103§112 | Non-Final OA | — | Pending | Mar 19, 2025 |
| 19074968 | ELECTRICALLY ANESTHETIZING A PERIPHERAL NERVE WITH ON-DEMAND ELECTRICAL NERVE BLOCK FOR CHRONIC PAIN MANAGEMENT | SCHAETZLE, KENNEDY | — | §102§103§112Other | Non-Final OA | — | Pending | Mar 10, 2025 |
| 18992764 | TRANSIENT ELECTRODES AND ASSOCIATED SYSTEMS AND METHODS FOR NEURAL MODULATION AND RECORDING | KOWALKOWSKI, FIONA MARGARET | 3792 | §102§103§112 | Non-Final OA | — | Pending | Jan 09, 2025 |
| 18878811 | SYNTHETIC SUPRACRESTAL DENTAL IMPLANT FIBERS | MORAN, EDWARD JOHN | 3772 | §102§103§112 | Non-Final OA | — | Pending | Dec 24, 2024 |
| 18967052 | MELT PROCESSED VIRAL NANOPARTICLE CONSTRUCTS | TRUONG, QUANGLONG N | — | §103DP | Non-Final OA | — | Pending | Dec 03, 2024 |
| 18950244 | PATTERNED STIMULATION INTENSITY FOR NEURAL STIMULATION | MORALES, JON ERIC C | — | §102Other | Non-Final OA | — | Pending | Nov 18, 2024 |
| 18914696 | VENTRAL SPINAL CORD STIMULATION FOR AT LEAST PARTIAL RESTORATION OF MOTOR FUNCTION | LEVICKY, WILLIAM J | — | §101§102§103§112 | Non-Final OA | — | Pending | Oct 14, 2024 |
| 18901645 | SYSTEMS AND METHODS TO ESTIMATE FORCE OF AN INSTRUMENT | KATZ, DYLAN MICHAEL | 3657 | §103 | Final Rejection | 53d overdue | Pending | Sep 30, 2024 |
| 18851170 | DETECTING AND MEASURING FAST OPTICAL SIGNALS (FOS) FROM ONE OR MORE CORNEAL NERVES FOR MONITORING A PATIENT'S HEALTH AND WELLNESS | LANGHALS, RENEE C | — | §103 | Non-Final OA | — | Pending | Sep 26, 2024 |
| 18849757 | WIRELESS, BATTERYLESS BLOOD PRESSURE SENSOR IMPLANT | UCHITEL, EMILY RUTH ABIGAIL | — | §102§103§112 | Non-Final OA | — | Pending | Sep 23, 2024 |
| 18835102 | BIOSYNTHETIC HEMOSTAT AND USES THEREOF | LOVE, TREVOR M | 1611 | §103 | Non-Final OA | — | Pending | Aug 01, 2024 |
| 18728949 | ISOCITRATE DEHYDROGENASE 1 INHIBITORS AND METHODS OF USE THEREOF | ROMERO, KRISTEN WANG | — | §102§103§112 | Non-Final OA | — | Pending | Jul 15, 2024 |
| 18721744 | TISSUE-SPECIFIC MANGANESE BASED MRI CONTRAST AGENTS | LEWOCZKO, EVAN MICHAEL | — | §102§103DP | Non-Final OA | — | Pending | Jun 19, 2024 |
| 18716576 | SOLID PARTICLES COMPRISING DECELLULARIZED CARDIAC TISSUE EXTRACELLULAR MATRIX AND METHODS FOR MAKING AND USING THE SAME | PHAN, DOAN THI-THUC | 1613 | §102§103§112 | Non-Final OA | — | Pending | Jun 05, 2024 |
| 18680965 | INTACT MASS SPECTROMETRY FOR DIRECT PROTEIN FOOTPRINTING DOSIMETRY USING COVALENT LABELING | MUI, CHRISTINE T | — | §101§102§103§112 | Non-Final OA | — | Pending | May 31, 2024 |
| 18626999 | COMPOSITIONS AND METHODS FOR TREATING VASCULAR DISEASE | BOWERS, ERIN M | 1653 | §103§112 | Non-Final OA | — | Pending | Apr 04, 2024 |
| 18608354 | COMPOSITIONS AND METHODS FOR TREATING TISSUE INJURY | COPPINS, JANET L | 1628 | §103 | Final Rejection | 25d overdue | Pending | Mar 18, 2024 |
| 18597085 | BIPHASIC OSTEOTENDINOUS REPAIR SCAFFOLDS | SCOTLAND, REBECCA LYNN | 1615 | §103§112 | Final Rejection | 70d | Pending | Mar 06, 2024 |
| 18687441 | TREATMENT OF NEURODEGENERATIVE DISEASES WITH HDAC INHIBITORS | VAJDA, KRISTIN ANN | 1622 | §102§112 | Non-Final OA | — | Pending | Feb 28, 2024 |
| 18687438 | METHODS AND COMPOSITION FOR TREATING NEURODEGENERATIVE DISEASES | BARRON, SEAN C | 1653 | §102§103§112 | Non-Final OA | — | Pending | Feb 28, 2024 |
| 18686729 | DEVICES, SYSTEM AND METHODS FOR EXERCISING WITH MUSCLE STIMULATION | GHAND, JENNIFER LEIGH-STEWAR | 3611 | §102§103 | Non-Final OA | — | Pending | Feb 26, 2024 |
| 18394838 | PROCESSES FOR PRODUCING AND REPROCESSING A RECYCLABLE ETHYLENE-VINYL ESTER POLYMER | MONTGOMERY, STEPHEN EDWARD | — | §103§112 | Non-Final OA | — | Pending | Dec 22, 2023 |
| 18545231 | PREDICTING NEO-ADJUVANT CHEMOTHERAPY RESPONSE FROM PRE-TREATMENT BREAST MAGNETIC RESONANCE IMAGING USING ARTIFICIAL INTELLIGENCE AND HER2 STATUS | LIU, GUOZHEN | 1686 | §101§103 | Non-Final OA | — | Pending | Dec 19, 2023 |
| 18517080 | COMPOSITIONS AND METHODS OF TREATING USHER SYNDROME III | NGUYEN, QUANG | 1631 | §103§112 | Final Rejection | 10d overdue | Pending | Nov 22, 2023 |
| 18561384 | PEPTIDE DRUG CONJUGATES SPECIFIC TO FIBRONECTIN ISOTYPES FOR CANCER THERAPY | REYNOLDS, FRED H | 1658 | §103§112DP | Non-Final OA | — | Pending | Nov 16, 2023 |
| 18283272 | METHODS AND COMPOSITIONS FOR ACCELERATING OLIGODENDROCYTE MATURATION | VAN BUREN, LAUREN K | 1638 | §102§103DP | Non-Final OA | — | Pending | Sep 21, 2023 |
| 18468009 | SYSTEMS AND METHODS TO FACILITATE DECISION MAKING FOR UTILITY NETWORKS | ROY, SANCHITA | — | §103§112 | Non-Final OA | — | Pending | Sep 15, 2023 |
| 18467820 | DIRECT RECYCLING AND RECOVERY METHOD OF CATHODE MATERIALS FROM SPENT LITHIUM ION BATTERIES | ESSEX, STEPHAN J | 1727 | §102§103 | Non-Final OA | — | Pending | Sep 15, 2023 |
| 18367356 | BIOACTIVE AGENT SPATIAL PATTERNED BIODEGRADABLE HYDROGELS | BURKE, MATTHEW RYAN | 1619 | §103§112 | Non-Final OA | — | Pending | Sep 12, 2023 |
| 18456958 | SYSTEMS AND METHODS FOR WATER DISTRIBUTION NETWORK LEAKAGE DETECTION AND/OR LOCALIZATION | WU, NICHOLAS S | 2148 | §103 | Final Rejection | — | Pending | Aug 28, 2023 |
| 18546648 | SUBCUTANEOUS PHOTOBIOMODULATION | KUO, JONATHAN T | 3792 | §103§112 | Final Rejection | 51d overdue | Pending | Aug 16, 2023 |
| 18546680 | PERCUTANEOUS PHOTOBIOMODULATION | MINCHELLA, ADAM ZACHARY | 3794 | §103 | Non-Final OA | — | Pending | Aug 16, 2023 |
| 18264161 | SYSTEMS AND METHODS FOR MULTI-REAGENT CHEMICAL LABELING OF BIOLOGICAL MOLECULES | COLE, HOUSTON DAVID | 1796 | §102§103§112 | Non-Final OA | — | Pending | Aug 03, 2023 |
| 18337677 | SYSTEMS AND METHODS FOR STIMULATION PARAMETER CONTRAST (SPC) IMAGING | WELCH, WILLOW GRACE | 3792 | §101§103 | Final Rejection | 54d | Pending | Jun 20, 2023 |
| 18323553 | COMBINATION OF RADIOMIC AND PATHOMIC FEATURES IN THE PREDICTION OF PROGNOSES FOR TUMORS | BURKE, TIONNA M | 2178 | §101§102§103 | Non-Final OA | — | Pending | May 25, 2023 |
| 18176877 | INHIBITION OF URACIL DNA GLYCOSYLASE IN THE OPEN CONFORMATION | BURKETT, DANIEL JOHN | 1624 | §103§112 | Non-Final OA | — | Pending | Mar 01, 2023 |
| 18109406 | COMPOSITIONS AND METHODS OF REDUCING SERUM CHOLESTEROL AND PCSK9 | WELLS, LAUREN QUINLAN | 1622 | §102§103§112 | Non-Final OA | 4d overdue | Pending | Feb 14, 2023 |
| 18167438 | METHODS OF SENSITIZING CANCER TO IMMUNOTHERAPY | SHUPE, ELIZABETH A | 1643 | §103 | Final Rejection | 67d overdue | Pending | Feb 10, 2023 |
| 18019993 | METHODS AND AGENTS FOR THE DETECTION AND TREATMENT OF CANCER | LIU, TRACY | 1614 | §103 | Final Rejection | — | Pending | Feb 06, 2023 |
| 17992994 | PREDICTING RECURRENCE IN EARLY STAGE NON-SMALL CELL LUNG CANCER (NSCLC) WITH INTEGRATED RADIOMIC AND PATHOMIC FEATURES | NASSER, ROBERT L | 3992 | §101 | Final Rejection | 30d | Pending | Nov 23, 2022 |
| 17910248 | TARGETED NANOBUBBLE THERAPY | MEJIAS, SAMANTHA LEE | 1618 | §103 | Non-Final OA | 36d overdue | Pending | Sep 08, 2022 |
| 17897278 | SYSTEMS AND METHODS FOR OBSTRUCTIVE SLEEP APNEA DETECTION AND MONITORING | LEE, MICHELLE J | 3786 | §101§103 | Final Rejection | — | Pending | Aug 29, 2022 |
| 17815563 | SYSTEMS AND METHODS FOR DATA ANALYTICS FOR VIRTUAL ENERGY AUDITS AND VALUE CAPTURE ASSESSMENT OF BUILDINGS | SINGLETARY, TYRONE E | 3625 | §103 | Non-Final OA | — | Pending | Jul 27, 2022 |
| 17855530 | BIOLOGICAL SAMPLING DEVICE AND METHOD OF USE | MELHUS, BENJAMIN S | 3791 | §103DP | Non-Final OA | — | Pending | Jun 30, 2022 |
| 17855515 | BIOLOGICAL SAMPLING DEVICE AND METHOD OF USE | MELHUS, BENJAMIN S | 3791 | §103DP | Non-Final OA | — | Pending | Jun 30, 2022 |
| 17661656 | MAPPING PERITUMORAL INFILTRATION AND PREDICTION OF RECURRENCE USING MULTI-PARAMETRIC MAGNETIC RESONANCE FINGERPRINTING RADIOMICS | NGUYEN, ALLEN H | 2683 | §101§102§103 | Non-Final OA | — | Pending | May 02, 2022 |
| 17624347 | PRIMING MEDIA AND METHODS FOR STEM CELL CULTURE AND THERAPY | JOHNSON, ALLISON MARIE | 1638 | §103§112 | Non-Final OA | 34d | Pending | Jan 02, 2022 |
| 17612047 | Variant Single-Chain Insulin Analogues | KONOPELSKI SNAVEL, SARA ELIZABETH | 1658 | §102§103DP | Non-Final OA | 10d overdue | Pending | Nov 17, 2021 |
| 17331375 | BIOLOGICAL SAMPLING DEVICE AND METHOD OF USE | KREMER, MATTHEW | 3791 | §103§112 | Non-Final OA | 30d overdue | Pending | May 26, 2021 |
| 16630271 | COMPOSITIONS AND METHODS FOR TREATING MYELIN DISORDERS | AUDET, MAURY A | 1654 | §103§112 | Final Rejection | 112d overdue | Pending | Jan 10, 2020 |
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