Prosecution Insights
Last updated: April 19, 2026

Klarquist Sparkman, LLP (Ott-Nih)

24 pending office actions • 17 clients

Portfolio Summary

24
Total Pending OAs
5
Final Rejections
19
Non-Final OAs

Client Portfolio (17 clients)

Client (Assignee)Pending OAs
The United States Department of Health and Human Services 4
The United States Department of Health and Human Services 3
The United States Department of Health and Human Services 2
The United States Department of Health and Human Services 2
The United States Of America, AS Represented By The Secretary, Depart. Of Health And Human Services 1
The United States Department of Health and Human Services 1
The United States Department of Health and Human Services 1
BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 1
UNIVERSITY OF MARYLAND, BALTIMORE 1
The United States Department of Health and Human Services 1
The United States Department of Health and Human Services 1
The United States Department of Health and Human Services 1
The United States Department of Health and Human Services 1
The United States Department of Health and Human Services 1
The United States Department of Health and Human Services 1
The United States Department of Health and Human Services 1
The United States Of America, AS Represented By The Secretary, Department Of Health And Human SE 1

Pending Office Actions

App #TitleClientExaminerArt UnitStatusFiled
18568738 COMPOUNDS THAT BIND NON-CANONICAL G-QUADRUPLEX STRUCTURES AND METHODS OF MAKING AND USING THE SAME The United States Department of Health and Human Services FETTEROLF, BRANDON J 1626 Non-Final OA Dec 08, 2023
18562806 METHODS TO GENERATE MACULAR, CENTRAL AND PERIPHERAL RETINAL PIGMENT EPITHELIAL CELLS The United States Department of Health and Human Services BERTOGLIO, VALARIE E 1632 Non-Final OA Nov 20, 2023
18557396 PREFUSION-STABILIZED LASSA VIRUS GLYCOPROTEIN COMPLEX AND ITS USE The United States Department of Health and Human Services CORNELIUS, CLAIRE ADRIENNE 1672 Non-Final OA Oct 26, 2023
18287630 HUMAN INSULIN C-ALPHA-PEPTIDES AND METHODS OF USE The United States Department of Health and Human Services LEE, JIA-HAI 1658 Non-Final OA Oct 19, 2023
18555137 RECOMBINANT CHIMERIC BOVINE/HUMAN PARAINFLUENZA VIRUS 3 EXPRESSING SARS-COV-2 SPIKE PROTEIN AND ITS USE The United States Department of Health and Human Services GRIZER, CASSANDRA SENN 1672 Non-Final OA Oct 12, 2023
18275925 ADJUVANTED MUCOSAL SUBUNIT VACCINES FOR PREVENTING SARS-COV-2 TRANSMISSION AND INFECTION The United States Of America, AS Represented By The Secretary, Depart. Of Health And Human Services GILL, RACHEL B 1671 Non-Final OA Aug 04, 2023
18263394 NEAR INFRARED PHOTOIMMUNOTHERAPY (NIR-PIT) COMBINATION THERAPY TO TREAT CANCER The United States Department of Health and Human Services GRAY, PHILLIP A 3783 Non-Final OA Jul 28, 2023
18359071 CHIMERIC ANTIGEN RECEPTORS TARGETING TUMOR ANTIGENS The United States Department of Health and Human Services STOICA, ELLY GERALD 1647 Non-Final OA Jul 26, 2023
18340863 PEPTIDE HYDROGEL COMPRISING HYDROPHILIC AZIDE-CONTAINING AMINO ACID AND ITS USE The United States Department of Health and Human Services FISHER, MELISSA L 1658 Non-Final OA Jun 25, 2023
18035240 MODIFIED NK CELLS WITH REDUCED CCR5 EXPRESSION AND METHODS OF THEIR USE The United States Department of Health and Human Services QIAN, CELINE X 1637 Non-Final OA May 03, 2023
18032132 HIGH CONCENTRATION METHYLCOBALAMIN OR COMBINATION OF METHYL- AND HYDROXY-COBALAMIN FOR THE TREATMENT OF COBALAMIN C DEFICIENCY DISORDERS The United States Department of Health and Human Services CRAIGO, BAHAR ALAWI 1699 Non-Final OA Apr 14, 2023
18031602 STABILIZED NOROVIRUS VIRUS-LIKE PARTICLES AS VACCINE IMMUNOGENS BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM BOESEN, AGNIESZKA 1672 Non-Final OA Apr 12, 2023
18028490 THERAPEUTICS AGAINST PATHOGENIC CORONAVIRUSES UNIVERSITY OF MARYLAND, BALTIMORE NOLAN, JASON MICHAEL 1623 Non-Final OA Mar 24, 2023
18014045 CYCLIC COMPOUNDS FOR USE IN TREATING RETINAL DEGENERATION The United States Department of Health and Human Services WELLS, LAUREN QUINLAN 1622 Final Rejection Dec 30, 2022
18011288 METHOTREXATE ANALOGS AND METHODS OF USE The United States Department of Health and Human Services SAMSELL, RILLA MARIE 1624 Non-Final OA Dec 19, 2022
18008393 LIVE ATTENUATED RESPIRATORY SYNCYTIAL VIRUS The United States Department of Health and Human Services HILL, MYRON G 1671 Non-Final OA Dec 05, 2022
17923394 ABERRANT POST-TRANSLATIONAL MODIFICATIONS (PTMS) IN METHYL- AND PROPIONIC ACIDEMIA AND A MUTANT SIRTUIN (SIRT) TO METABOLIZE PTMS The United States Department of Health and Human Services BOWLES, DAVID PAUL 1654 Non-Final OA Nov 04, 2022
17783171 ANTIBODY-DRUG CONJUGATES SPECIFIC FOR CD276 AND USES THEREOF The United States Department of Health and Human Services PETERS, ALEC JON 1641 Final Rejection Jun 07, 2022
17632783 CANCER DETECTION AND CLASSIFICATION The United States Department of Health and Human Services BUCHANAN, BAILEY CHEYENNE 1682 Final Rejection Feb 03, 2022
17631600 RADIOLABELED SUGARS FOR IMAGING OF FUNGAL INFECTIONS The United States Department of Health and Human Services DONOHUE, SEAN R 1618 Non-Final OA Jan 31, 2022
17346630 METHODS TO ELIMINATE CANCER STEM CELLS BY TARGETING CD47 The United States Department of Health and Human Services MATALKAH, FATIMAH KHALAF 1638 Final Rejection Jun 14, 2021
17167737 APOPTOTIC CELL-MEDIATED INDUCTION OF ANTIGEN SPECIFIC REGULATORY T-CELLS FOR THE THERAPY OF AUTOIMMUNE DISEASES IN ANIMALS AND HUMANS The United States Department of Health and Human Services JOHANSEN, PETER N. 1644 Final Rejection Feb 04, 2021
17260905 INTRAOCULAR DELIVERY OF GENE THERAPY EXPRESSION VECTORS The United States Department of Health and Human Services DIOP, FATIMATA SAHRA 3783 Non-Final OA Jan 15, 2021
16971288 USE OF IL-34 TO TREAT RETINAL INFLAMMATION AND NEURODEGENERATION The United States Of America, AS Represented By The Secretary, Department Of Health And Human SE FONTAINHAS, AURORA M 1675 Non-Final OA Aug 19, 2020

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