Prosecution Insights
Last updated: July 17, 2026

Leydig Voit & Mayer, Ltd. (Nih)

28 pending office actions • 6 clients • 27 examiners • 22 art units • 0 of 28 (0%) have an AI response strategy ready • 29 patents granted in the last 365 days

Quality Metrics (n=1400 apps, methodology: how we score firms)

86.0%
Allowance Rate
n=1400
+1.00σ
Allowance Rate (norm)
n=1400
3.9
OAs to Allowance
n=624
-0.11σ
OAs to Allow (norm)
n=624
1112 days
Time to Allowance
n=624
+11.1pp
Interview Lift
n=1400
29.3%
RCE Rate
n=1400
1.2%
Appeal Rate
n=1400

Rejection Performance (% of received rejections ultimately overcome)

84.6%
§101 Overcome
n=26
89.9%
§102 Overcome
n=109
82.4%
§103 Overcome
n=272
90.6%
§112 Overcome
n=180

Specialization & Scale

A61K, A61P, C07K
Top CPC Subclasses
57%
Top-3 CPC Share
n=1400
0
Practitioners
n=1400
Apps / Practitioner
n=1400 (min 20)

Portfolio Summary

28
Total Pending OAs
15
Non-Final OAs
12
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 6 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

3
Overdue
1
Due this week
0
Due this month
0
Due in next 60 days
2
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 6 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (3)Due ≤ 7 days (1)Due later (2)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

1
Hard (4%)
15
Medium (54%)
11
Easy (39%)
1
Unknown (4%)

Rejection Statute Mix

BucketCases
§101 only1 (4%)
§103 only13 (46%)
§102 only2 (7%)
§112 only5 (18%)
Double-patenting only6 (21%)
No statute on record1 (4%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

25
Life Sciences
89% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
1
Mechanical / Eng
4% of docket
2
Business / Other
7% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

280 h
Manual time on pending OAs
56 h
Time saved (low, 20%)
98 h
Time saved (mid, 35%)
2.5 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
SANG, HONG 2 54.8% +62.2%
MONTGOMERY, ANN Y 1 69.4% +27.1%
SHIM, DAVID M. 1 58.0% +55.9%
JACKSON-TONGUE, LAKIA J 1 68.9% +20.6%
BURKHART, MICHAEL D 1 62.5% +11.1%
BELYAVSKYI, MICHAIL A 1 64.0% +27.5%
LANDSMAN, ROBERT S 1 81.4% +13.1%
HADDAD, MAHER M 1 50.5% +54.3%
WEBB, WALTER E 1 46.5% +18.6%
BRADLEY, CHRISTINA 1 62.8% +33.2%

Quick Wins (1)

Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
18282919 BICISTRONIC CHIMERIC ANTIGEN RECEPTORS DESIGNED TO REDUCE RETROVIRAL RECOMBINATION AND USES THEREOF LANDSMAN, ROBERT S

Hard Cases (1)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
17620248 INTERLEUKIN-27 PRODUCING B-CELLS AND USES THEREOF THUESON, HANNA MARIE

Interview Candidates (11)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18722188 METHODS AND SYSTEMS FOR ANALYZING TARGET ENGAGEMENT DATA FROM BIOLOGICAL ASSAYS MONTGOMERY, ANN Y 30d overdue
18037379 TYROSYL-LOCK PEPTIDES BRADLEY, CHRISTINA 4d overdue
18271583 EXOSOMES COMPRISING IL-35 OR IL-27 AND USES THEREOF WEBB, WALTER E 76d
18735506 FORMULATIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF TUMOR METASTASIS AND TUMORIGENESIS SHIM, DAVID M.
18664031 BRACHYURY DELETION MUTANTS, NON-YEAST VECTORS ENCODING BRACHYURY DELETION MUTANTS, AND THEIR USE JACKSON-TONGUE, LAKIA J
18644724 BICISTRONIC CHIMERIC ANTIGEN RECEPTORS AND THEIR USES BURKHART, MICHAEL D
18583139 T CELL RECEPTORS RECOGNIZING MUTATED P53 BELYAVSKYI, MICHAIL A
18502993 M971 CHIMERIC ANTIGEN RECEPTORS SANG, HONG

Client Portfolio (6 clients)

Top Art Units

Art UnitApps
16383
16122
16322
16781
16261
16451
16441
16461
16471
16411

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
18722188 METHODS AND SYSTEMS FOR ANALYZING TARGET ENGAGEMENT DATA FROM BIOLOGICAL ASSAYS The United States Department of Health and Human Services MONTGOMERY, ANN Y 1678 §112 Non-Final OA 30d overdue Pending Jun 20, 2024
18735506 FORMULATIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF TUMOR METASTASIS AND TUMORIGENESIS Northwestern University SHIM, DAVID M. 1626 §103 Non-Final OA Pending Jun 06, 2024
18664031 BRACHYURY DELETION MUTANTS, NON-YEAST VECTORS ENCODING BRACHYURY DELETION MUTANTS, AND THEIR USE The United States Department of Health and Human Services JACKSON-TONGUE, LAKIA J 1645 DP Non-Final OA Pending May 14, 2024
18644724 BICISTRONIC CHIMERIC ANTIGEN RECEPTORS AND THEIR USES The United States Department of Health and Human Services BURKHART, MICHAEL D DP Non-Final OA Pending Apr 24, 2024
18583139 T CELL RECEPTORS RECOGNIZING MUTATED P53 The United States Department of Health and Human Services BELYAVSKYI, MICHAIL A 1644 Other Non-Final OA Pending Feb 21, 2024
18502993 M971 CHIMERIC ANTIGEN RECEPTORS The United States Department of Health and Human Services SANG, HONG 1646 DP Non-Final OA Pending Nov 06, 2023
18503107 M971 CHIMERIC ANTIGEN RECEPTORS The United States Department of Health and Human Services SANG, HONG DP Non-Final OA Pending Nov 06, 2023
18282919 BICISTRONIC CHIMERIC ANTIGEN RECEPTORS DESIGNED TO REDUCE RETROVIRAL RECOMBINATION AND USES THEREOF The United States Department of Health and Human Services LANDSMAN, ROBERT S 1647 §103 Non-Final OA Pending Sep 19, 2023
18277521 HLA CLASS I-RESTRICTED T CELL RECEPTORS AGAINST CD22 The United States Department of Health and Human Services HADDAD, MAHER M 1641 §112 Non-Final OA Pending Aug 16, 2023
18271583 EXOSOMES COMPRISING IL-35 OR IL-27 AND USES THEREOF The United States Department of Health and Human Services WEBB, WALTER E 1612 §103 Non-Final OA 76d Pending Jul 10, 2023
18037379 TYROSYL-LOCK PEPTIDES The University of Queensland BRADLEY, CHRISTINA 1654 §112 Non-Final OA 4d overdue Pending May 17, 2023
18028463 PLK1 POLO BOX DOMAIN INHIBITORS AND METHOD OF TREATING CANCER The United States Department of Health and Human Services HERNANDEZ, JACKSON J 1627 §102 Final Rejection Pending Mar 24, 2023
18026421 NOVEL ADENO-ASSOCIATED VIRAL (AAV) VECTORS TO TREAT HEREDITARY METHYLMALONIC ACIDEMIA (MMA) CAUSED BY METHYLMALONYL-COA MUTASE (MMUT) DEFICIENCY The United States Department of Health and Human Services ARMATO JR, DENNIS IGNATIUS 1651 DP Final Rejection Pending Mar 15, 2023
17910911 SYSTEMS, METHODS, AND DEVICES FOR EX VIVO ANALYSIS OF RESECTED TISSUE SAMPLES The United States Department of Health and Human Services HOBBS, MICHAEL L 1799 §103 Non-Final OA 6d Pending Feb 15, 2023
18147786 METHODS OF ISOLATING T CELL RECEPTORS HAVING ANTIGENIC SPECIFICITY FOR A CANCER-SPECIFIC MUTATION The United States Of America, A Represented By The Secretary, Department Of Health And Human Servi CORDAS, EMILY ANN 1632 §103 Final Rejection Pending Dec 29, 2022
18012056 HLA CLASS I-RESTRICTED T CELL RECEPTORS AGAINST CD20 The United States Department of Health and Human Services WEIDNER, ADAM M 1675 §112 Non-Final OA Pending Dec 21, 2022
18056356 GENE THERAPY FOR COMBINED METHYLMALONIC ACIDEMIA/ACIDURIA AND HYPERHOMOCYSTEINEMIA/HOMOCYSTINURIA, COBALAMIN C TYPE, AND DEFICIENCY OF MMACHC The United States Department of Health and Human Services SHIN, DANA H 1635 §112 Final Rejection 78d Pending Nov 17, 2022
17918725 THYCLOTIDES The United States Department of Health and Human Services GALSTER, SAMUEL LEONARD 1693 §103 Non-Final OA Pending Oct 13, 2022
17912315 METHODS OF ISOLATING T-CELLS AND T-CELL RECEPTORS FROM TUMOR BY SINGLE-CELL ANALYSIS FOR IMMUNOTHERAPY The United States Department of Health and Human Services BUNKER, AMY M 1684 §103 Final Rejection Pending Sep 16, 2022
17793753 HUMAN IMMUNOGENIC EPITOPES OF HEMO AND HHLA2 HUMAN ENDOGENOUS RETROVIRUSES (HERVS) The United States Department of Health and Human Services HOLLAND, PAUL J 1656 §103 Final Rejection Pending Jul 19, 2022
17790939 METHODS OF PRODUCING T CELL POPULATIONS USING INDUCED PLURIPOTENT STEM CELLS The United States Department of Health and Human Services TAKENAKA, RISA 1632 §103 Non-Final OA Pending Jul 05, 2022
17557845 CHIMERIC ANTIGEN RECEPTORS TARGETING CD-19 The United States Department of Health and Human Services HILL, KEVIN KAI 1638 DP Final Rejection Pending Dec 21, 2021
17620248 INTERLEUKIN-27 PRODUCING B-CELLS AND USES THEREOF The United States Department of Health and Human Services THUESON, HANNA MARIE 1638 §101 Final Rejection Pending Dec 17, 2021
17430891 HANDGRIP RELAXOMETER SYSTEM The United States Department of Health and Human Services MARMOR II, CHARLES ALAN 3791 §103 Final Rejection Pending Aug 13, 2021
17429391 GENETICALLY MODIFIED HEMATOPOIETIC STEM AND PROGENITOR CELLS (HSPCS) AND MESENCHYMAL CELLS AS A PLATFORM TO REDUCE OR PREVENT METASTASIS, TREAT AUTOIMMUNE AND INFLAMMATORY DISORDERS, AND REBALANCE THE IMMUNE MILIEU AND DYSREGULATED NICHES The United States Department of Health and Human Services ROGERS, ERIC JASON 1638 §103 Final Rejection 50d overdue Pending Aug 09, 2021
16980205 ANTI-CD33 CHIMERIC ANTIGEN RECEPTORS AND THEIR USES The United States Department of Health and Human Services EDGINGTONGIORDANO, FRANCESCA 1643 §103 Non-Final OA Pending Sep 11, 2020
16977897 POSITIVE ALLOSTERIC MODULATORS OF DOPAMINE 1 RECEPTOR AND METHOD OF USE THEREOF The University of North Carolina at Chapel Hill OTTON, ALICIA L 1699 §102 Final Rejection Pending Sep 03, 2020
16758009 ISOTOPIC BIOMARKERS OF ORGANIC ACIDEMIAS The United States Department of Health and Human Services COHEN, MICHAEL P 1612 §103 Final Rejection Pending Apr 21, 2020

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