Prosecution Insights
Last updated: July 17, 2026

Marshall, Gerstein & Borun LLP (Biomarin)

5 pending office actions • 3 clients • 5 examiners • 5 art units • 0 of 5 (0%) have an AI response strategy ready • 1 patents granted in the last 365 days

Quality Metrics (n=229 apps, methodology: how we score firms)

75.7%
Allowance Rate
n=229
+0.69σ
Allowance Rate (norm)
n=229
3.4
OAs to Allowance
n=103
-0.18σ
OAs to Allow (norm)
n=103
1028 days
Time to Allowance
n=103
+23.7pp
Interview Lift
n=229
25.0%
RCE Rate
n=229
0.0%
Appeal Rate
n=229

Rejection Performance (% of received rejections ultimately overcome)

§101 Overcome
n=1 (min 20)
§102 Overcome
n=10 (min 20)
81.0%
§103 Overcome
n=42
88.0%
§112 Overcome
n=25

Specialization & Scale

A61K, A61P, C12N
Top CPC Subclasses
56%
Top-3 CPC Share
n=229
0
Practitioners
n=229
Apps / Practitioner
n=229 (min 20)

Portfolio Summary

5
Total Pending OAs
5
Non-Final OAs
0
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 3 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

2
Overdue
0
Due this week
1
Due this month
0
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 3 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (2)Due ≤ 30 days (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

1
Hard (20%)
2
Medium (40%)
1
Easy (20%)
1
Unknown (20%)

Rejection Statute Mix

BucketCases
§101 only1 (20%)
§103 only2 (40%)
Double-patenting only1 (20%)
No statute on record1 (20%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

5
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

50 h
Manual time on pending OAs
10 h
Time saved (low, 20%)
18 h
Time saved (mid, 35%)
0.4 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
HELLMAN, KRISTINA M 1 65.7% +54.8%
EIX, EMILY FAY 1 53.6% +68.4%
SZPERKA, MICHAEL EDWARD 1 62.6% +37.0%
ALLEN, MARIANNE P 1 60.1% +18.2%
REYNOLDS, FRED H 1 33.1% +39.1%

Hard Cases (1)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
18785340 Use of C-Type Natriuretic Peptide Variants to Treat Skeletal Dysplasia HELLMAN, KRISTINA M

Interview Candidates (5)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 5 ordered by deadline are shown.

App #TitleExaminerDue in
17634034 Hydrophobic Peptide Salts for Extended Release Compositions REYNOLDS, FRED H 334d overdue
17829620 Lysosomal Targeting Peptides and Uses Thereof ALLEN, MARIANNE P 38d overdue
18148888 COMPOSITIONS AND METHODS FOR TREATING ALLOGRAFT VASCULOPATHY, MOYAMOYA DISEASE, MOYAMOYA SYNDROME AND INTIMAL PROLIFERATION SZPERKA, MICHAEL EDWARD 14d
18785340 Use of C-Type Natriuretic Peptide Variants to Treat Skeletal Dysplasia HELLMAN, KRISTINA M
18529611 METHODS FOR TREATING LYSOSOMAL STORAGE DISEASES EIX, EMILY FAY

Client Portfolio (3 clients)

Top Art Units

Art UnitApps
16541
16531
16411
16471
16581

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
18785340 Use of C-Type Natriuretic Peptide Variants to Treat Skeletal Dysplasia BIOMARIN PHARMACEUTICAL INC. HELLMAN, KRISTINA M 1654 §101 Non-Final OA Pending Jul 26, 2024
18529611 METHODS FOR TREATING LYSOSOMAL STORAGE DISEASES Rutgers, The State University Of New Jersey EIX, EMILY FAY 1653 DP Non-Final OA Pending Dec 05, 2023
18148888 COMPOSITIONS AND METHODS FOR TREATING ALLOGRAFT VASCULOPATHY, MOYAMOYA DISEASE, MOYAMOYA SYNDROME AND INTIMAL PROLIFERATION Westfälische Wilhelms-Universität Münster SZPERKA, MICHAEL EDWARD 1641 §103 Non-Final OA 14d Pending Dec 30, 2022
17829620 Lysosomal Targeting Peptides and Uses Thereof BIOMARIN PHARMACEUTICAL INC. ALLEN, MARIANNE P 1647 §103 Non-Final OA 38d overdue Pending Jun 01, 2022
17634034 Hydrophobic Peptide Salts for Extended Release Compositions BIOMARIN PHARMACEUTICAL INC. REYNOLDS, FRED H 1658 Other Non-Final OA 334d overdue Pending Feb 09, 2022

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