Prosecution Insights
Last updated: October 02, 2026

Arbor Biotechnologies Inc.

Technology area: Biotechnology & Pharmaceuticals

10 pending office actions • 4 art units • 8 examiners • 0 of 10 (0%) have an AI response strategy ready • 8 patents granted in the last 365 days

Analysis

Arbor Biotechnologies Inc. has 10 pending office actions in the Biotechnology & Pharmaceuticals technology area. These actions are distributed among 8 distinct examiners and 4 distinct art units. This ratio of 10 actions to 8 examiners indicates that most examiners are handling only a single matter, though some overlap exists. The involvement of 4 distinct art units suggests that the Biotechnology & Pharmaceuticals filings are categorized into several specialized groups.

LIPPOLIS, ALEXANDRA ROSE is the busiest examiner for this company, currently overseeing 3 pending office actions. This accounts for a notable portion of the 10 pending office actions in the portfolio. Practitioners should prioritize understanding the specific tendencies of LIPPOLIS, ALEXANDRA ROSE, as her 3 actions represent the highest concentration of pending work within the 4 distinct art units. Managing 10 pending office actions across 8 distinct examiners requires a robust tracking system to maintain alignment. The 3 actions under LIPPOLIS, ALEXANDRA ROSE are the most critical single-examiner cluster for the firm to monitor.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

10
Total Pending OAs
8
Non-Final OAs
2
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 2 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

1
Overdue
0
Due this week
0
Due this month
1
Due in next 60 days
0
Due later

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

4
Hard (40%)
4
Medium (40%)
2
Easy (20%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other1 (10%)
§103 only1 (10%)
§112 only1 (10%)
Double-patenting only1 (10%)
Double-patenting + other3 (30%)
Multi-statute (no §101)3 (30%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

7
Life Sciences
70% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
3
Business / Other
30% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

100 h
Manual time on pending OAs
20 h
Time saved (low, 20%)
35 h
Time saved (mid, 35%)
0.9 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
LIPPOLIS, ALEXANDRA ROSE 3 46.9% +59.0%
ZARA, JANE J 1 71.0% +16.1%
HUDSON, AMY ROSE 1 74.9% +11.5%
CHONG, KIMBERLY 1 72.4% +13.0%
SU-TOBON, QIWEN NMN 1 66.7% +66.7%
KONOPKA, CATHERINE ANNE 1 58.1% +65.0%
TINSLEY, BRENDAN THOMAS 1 58.7% +73.9%
DACE DENITO, ALEXANDRA GERALDINE 1 56.3% +40.2%

Hard Cases (4)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 4 ordered by deadline are shown.

App #TitleExaminerDue in
18682774 COMPOSITIONS COMPRISING A VARIANT CAS12I3 POLYPEPTIDE AND USES THEREOF LIPPOLIS, ALEXANDRA ROSE —
18565567 GENE EDITING SYSTEMS COMPRISING AN RNA GUIDE TARGETING TRANSTHYRETIN (TTR) AND USES THEREOF HUDSON, AMY ROSE —
18274697 CRISPR-ASSOCIATED TRANSPOSON SYSTEMS AND METHODS OF USING SAME LIPPOLIS, ALEXANDRA ROSE —
18274698 CRISPR-ASSOCIATED TRANSPOSON SYSTEMS AND METHODS OF USING SAME LIPPOLIS, ALEXANDRA ROSE —

Interview Candidates (10)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17497725 NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS DACE DENITO, ALEXANDRA GERALDINE 45d overdue
18251183 COMPOSITIONS COMPRISING AN RNA GUIDE TARGETING BCL11A AND USES THEREOF KONOPKA, CATHERINE ANNE 50d
18682774 COMPOSITIONS COMPRISING A VARIANT CAS12I3 POLYPEPTIDE AND USES THEREOF LIPPOLIS, ALEXANDRA ROSE —
18565575 GENE EDITING SYSTEMS COMPRISING AN RNA GUIDE TARGETING HYDROXYACID OXIDASE 1 (HAO1) AND USES THEREOF ZARA, JANE J —
18565567 GENE EDITING SYSTEMS COMPRISING AN RNA GUIDE TARGETING TRANSTHYRETIN (TTR) AND USES THEREOF HUDSON, AMY ROSE —
18281201 COMPOSITIONS COMPRISING A VARIANT POLYPEPTIDE AND USES THEREOF CHONG, KIMBERLY —
18274697 CRISPR-ASSOCIATED TRANSPOSON SYSTEMS AND METHODS OF USING SAME LIPPOLIS, ALEXANDRA ROSE —
18274698 CRISPR-ASSOCIATED TRANSPOSON SYSTEMS AND METHODS OF USING SAME LIPPOLIS, ALEXANDRA ROSE —

Top Art Units

Art UnitApps
1636 3
1637 2
1635 1
1634 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18682774 COMPOSITIONS COMPRISING A VARIANT CAS12I3 POLYPEPTIDE AND USES THEREOF LIPPOLIS, ALEXANDRA ROSE — §101§112 Non-Final OA — Pending Feb 09, 2024
18565575 GENE EDITING SYSTEMS COMPRISING AN RNA GUIDE TARGETING HYDROXYACID OXIDASE 1 (HAO1) AND USES THEREOF ZARA, JANE J — §112 Non-Final OA — Pending Nov 30, 2023
18565567 GENE EDITING SYSTEMS COMPRISING AN RNA GUIDE TARGETING TRANSTHYRETIN (TTR) AND USES THEREOF HUDSON, AMY ROSE — §102§103 Non-Final OA — Pending Nov 30, 2023
18281201 COMPOSITIONS COMPRISING A VARIANT POLYPEPTIDE AND USES THEREOF CHONG, KIMBERLY 1636 §112DP Non-Final OA — Pending Sep 08, 2023
18274697 CRISPR-ASSOCIATED TRANSPOSON SYSTEMS AND METHODS OF USING SAME LIPPOLIS, ALEXANDRA ROSE 1637 §102§103 Non-Final OA — Pending Jul 27, 2023
18274698 CRISPR-ASSOCIATED TRANSPOSON SYSTEMS AND METHODS OF USING SAME LIPPOLIS, ALEXANDRA ROSE 1637 §102§103 Non-Final OA — Pending Jul 27, 2023
18262086 CAS12I2 FUSION MOLECULES AND USES THEREOF SU-TOBON, QIWEN NMN 1636 §103§112DP Non-Final OA — Pending Jul 19, 2023
18251183 COMPOSITIONS COMPRISING AN RNA GUIDE TARGETING BCL11A AND USES THEREOF KONOPKA, CATHERINE ANNE 1635 §103DP Final Rejection 50d Pending Apr 28, 2023
18010680 CELLS MODIFIED BY A CAS12I POLYPEPTIDE TINSLEY, BRENDAN THOMAS 1634 §103 Final Rejection — Pending Dec 15, 2022
17497725 NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS DACE DENITO, ALEXANDRA GERALDINE 1636 DP Non-Final OA 45d overdue Pending Oct 08, 2021

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