Prosecution Insights
Last updated: October 04, 2026

Krystal Biotech Inc.

Technology area: Biotechnology & Pharmaceuticals

4 pending office actions • 3 art units • 4 examiners • 0 of 4 (0%) have an AI response strategy ready • 3 patents granted in the last 365 days

Analysis

Krystal Biotech Inc. is currently managing 4 pending office actions within the Biotechnology & Pharmaceuticals technology area. These actions are distributed among 4 distinct examiners, which means each examiner is responsible for one pending matter. The portfolio is spread across 3 distinct art units, suggesting that the company's applications cover several different technical classifications within the biotech field. This distribution indicates a moderately diverse set of innovations currently undergoing review.

WILSON, MICHAEL C is the busiest examiner for the portfolio, currently holding 1 pending office action. Since there are 4 pending office actions and 4 distinct examiners, the workload is evenly split among the assigned staff. The use of 3 distinct art units indicates that while the technology area is consistent, the specific subject matter is varied enough to require review by multiple administrative groups. This profile shows an active prosecution phase with a balanced distribution of cases across 4 distinct examiners and 3 distinct art units, requiring the company to navigate different examiner preferences across multiple units.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

4
Total Pending OAs
2
Non-Final OAs
2
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 2 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

1
Overdue
0
Due this week
1
Due this month
0
Due in next 60 days
0
Due later

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

2
Hard (50%)
1
Medium (25%)
1
Easy (25%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§103 only1 (25%)
§112 only1 (25%)
Multi-statute (no §101)2 (50%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

3
Life Sciences
75% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
1
Business / Other
25% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

40 h
Manual time on pending OAs
8 h
Time saved (low, 20%)
14 h
Time saved (mid, 35%)
0.3 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
WILSON, MICHAEL C 1 41.5% +17.9%
NICOL, ALEXANDER W 1 42.9% +43.1%
KELLY, ROBERT M 1 74.1% +24.6%
BUTTICE, AUDREY L 1 47.9% +25.9%

Hard Cases (2)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 2 ordered by deadline are shown.

App #TitleExaminerDue in
17255383 COMPOSITIONS AND METHODS FOR ANTIBODY DELIVERY BUTTICE, AUDREY L 29d
18896155 Recombinant Nucleic Acids Encoding Cosmetic Protein(s) For Aesthetic Applications WILSON, MICHAEL C —

Interview Candidates (4)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 4 ordered by deadline are shown.

App #TitleExaminerDue in
18187884 COMPOSITIONS AND METHODS FOR TREATMENT OF NETHERTON SYNDROME KELLY, ROBERT M 44d overdue
17255383 COMPOSITIONS AND METHODS FOR ANTIBODY DELIVERY BUTTICE, AUDREY L 29d
18896155 Recombinant Nucleic Acids Encoding Cosmetic Protein(s) For Aesthetic Applications WILSON, MICHAEL C —
18634382 Methods and Compositions for Treating Conditions Involving the Eye NICOL, ALEXANDER W —

Top Art Units

Art UnitApps
1634 1
1638 1
1647 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18896155 Recombinant Nucleic Acids Encoding Cosmetic Protein(s) For Aesthetic Applications WILSON, MICHAEL C — §103§112Other Non-Final OA — Pending Sep 25, 2024
18634382 Methods and Compositions for Treating Conditions Involving the Eye NICOL, ALEXANDER W 1634 §103 Final Rejection — Pending Apr 12, 2024
18187884 COMPOSITIONS AND METHODS FOR TREATMENT OF NETHERTON SYNDROME KELLY, ROBERT M 1638 §112 Non-Final OA 44d overdue Pending Mar 22, 2023
17255383 COMPOSITIONS AND METHODS FOR ANTIBODY DELIVERY BUTTICE, AUDREY L 1647 §103§112Other Final Rejection 29d Pending Jul 19, 2021

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