Prosecution Insights
Last updated: May 29, 2026

Spark Therapeutics Inc.

8 pending office actions • 6 art units • 8 examiners • 0 of 8 (0%) have an AI response strategy ready • 2 patents granted in the last 365 days

Portfolio Summary

8
Total Pending OAs
4
Non-Final OAs
4
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 7 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

5
Overdue
0
Due this week
1
Due this month
0
Due in next 60 days
1
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 7 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (5)Due ≤ 30 days (1)Due later (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

0
Hard (0%)
5
Medium (62%)
2
Easy (25%)
1
Unknown (12%)

Rejection Statute Mix

BucketCases
§103 only4 (50%)
§102 only1 (12%)
§112 only2 (25%)
No statute on record1 (12%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

8
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

80 h
Manual time on pending OAs
16 h
Time saved (low, 20%)
28 h
Time saved (mid, 35%)
0.7 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
TINSLEY, BRENDAN THOMAS 1 54.5% +71.1%
RONEY, CELESTE A 1 62.3% +18.0%
MATALKAH, FATIMAH KHALAF 1 56.3% +11.5%
ABBOTT, KODYE LEE 1 52.4% +62.5%
GILL, RACHEL B 1 65.6% +27.7%
TSAY, MARSHA M 1 45.6% +52.3%
NICOL, ALEXANDER W 1 42.0% +44.9%
GRABER, JAMES J 1 46.2% +56.1%

Interview Candidates (8)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17759183 COMPOSITIONS AND METHODS FOR INCREASING OR ENHANCING TRANSDUCTION OF GENE THERAPY VECTORS AND FOR REMOVING OR REDUCING IMMUNOGLOBULINS MATALKAH, FATIMAH KHALAF 114d overdue
16088693 CELL LINE FOR RECOMBINANT PROTEIN AND/OR VIRAL VECTOR PRODUCTION NICOL, ALEXANDER W 36d overdue
16627227 AAV VECTOR COLUMN PURIFICATION METHODS TSAY, MARSHA M 18d overdue
17862622 COMPOSITIONS AND METHODS FOR INCREASING OR ENHANCING TRANSDUCTION OF GENE THERAPY VECTORS AND FOR REMOVING OR REDUCING IMMUNOGLOBULINS ABBOTT, KODYE LEE 15d overdue
18262959 Compositions and Methods for Treating Hereditary Angioedema TINSLEY, BRENDAN THOMAS 9d overdue
15780542 SCALABLE METHODS FOR PRODUCING RECOMBINANT ADENO-ASSOCIATED VIRAL (AAV) VECTOR IN SERUM-FREE SUSPENSION CELL CULTURE SYSTEM SUITABLE FOR CLINICAL USE GRABER, JAMES J 22d
18258981 Methods of Enhancing Non-Viral Gene Therapy RONEY, CELESTE A 75d
16631692 APHERESIS METHODS AND USES GILL, RACHEL B

Top Art Units

Art UnitApps
1634 3
1612 1
1638 1
1671 1
1656 1
1631 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18262959 Compositions and Methods for Treating Hereditary Angioedema TINSLEY, BRENDAN THOMAS 1634 §112 Non-Final OA 9d overdue Pending Jul 26, 2023
18258981 Methods of Enhancing Non-Viral Gene Therapy RONEY, CELESTE A 1612 §103 Non-Final OA 75d Pending Jun 22, 2023
17759183 COMPOSITIONS AND METHODS FOR INCREASING OR ENHANCING TRANSDUCTION OF GENE THERAPY VECTORS AND FOR REMOVING OR REDUCING IMMUNOGLOBULINS MATALKAH, FATIMAH KHALAF 1638 §103 Non-Final OA 114d overdue Pending Jul 20, 2022
17862622 COMPOSITIONS AND METHODS FOR INCREASING OR ENHANCING TRANSDUCTION OF GENE THERAPY VECTORS AND FOR REMOVING OR REDUCING IMMUNOGLOBULINS ABBOTT, KODYE LEE 1634 §112 Final Rejection 15d overdue Pending Jul 12, 2022
16631692 APHERESIS METHODS AND USES GILL, RACHEL B 1671 §102 Final Rejection Pending Jan 16, 2020
16627227 AAV VECTOR COLUMN PURIFICATION METHODS TSAY, MARSHA M 1656 Other Non-Final OA 18d overdue Pending Dec 27, 2019
16088693 CELL LINE FOR RECOMBINANT PROTEIN AND/OR VIRAL VECTOR PRODUCTION NICOL, ALEXANDER W 1634 §103 Final Rejection 36d overdue Pending Sep 26, 2018
15780542 SCALABLE METHODS FOR PRODUCING RECOMBINANT ADENO-ASSOCIATED VIRAL (AAV) VECTOR IN SERUM-FREE SUSPENSION CELL CULTURE SYSTEM SUITABLE FOR CLINICAL USE GRABER, JAMES J 1631 §103 Final Rejection 22d Pending May 31, 2018

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