Technology area: Biotechnology & Pharmaceuticals
73 pending office actions • 57 art units • 69 examiners • 0 of 73 (0%) have an AI response strategy ready • 63 patents granted in the last 365 days
The Regents of the University of Colorado has 74 pending office actions in Biotechnology & Pharmaceuticals. The matters span 70 distinct examiners and 56 distinct art units, indicating a highly distributed prosecution portfolio across a wide range of biotechnology examination settings.
PAZ ESTEVEZ, GUILLERMO G is the busiest listed examiner, with 3 pending matters. That assignment provides one coordination point, but the breadth of the docket requires systematic tracking of examiner positions, art-unit practices, claim terminology, and disclosure consistency across the portfolio.
Based on the USPTO statutory response window for each pending office action. 20 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 20 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 + other | 4 (5%) |
| §103 only | 20 (27%) |
| §102 only | 3 (4%) |
| §112 only | 7 (10%) |
| Double-patenting + other | 1 (1%) |
| Multi-statute (no §101) | 38 (52%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| PAZ ESTEVEZ, GUILLERMO G | 3 | 20.0% | +6.8% |
| SEAMAN, D MARGARET M | 2 | 76.6% | +8.1% |
| MCCLURE, CHRISTINA D | 2 | 29.9% | +33.1% |
| SHIRSAT, MARCELA | 1 | 73.8% | +18.9% |
| LEE, SARAH YEO | 1 | 100.0% | +0.0% |
| KIM, KIHO | 1 | 85.4% | +4.4% |
| HUANG, DAVID Z | 1 | 80.4% | +13.2% |
| SWIFT, CANDICE LEE | 1 | 56.6% | +37.2% |
| OGUNBIYI, OLUWATOSIN A | 1 | 63.8% | +41.2% |
| BUCK, LINDSEY A | 1 | 49.4% | +34.3% |
Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 2 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 19178366 | OPTIMIZED VIRTUAL REALITY SYSTEM | LEE, SARAH YEO | — |
| 18972502 | FLOATING PLATFORM SYSTEM FOR MECHANICAL TESTING OF GELS AND TISSUES | HUANG, DAVID Z | — |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18042509 | ULTRAVIOLET-ABSORPTIVE NANOPARTICLES AND MICROPARTICLES FOR INTRADERMAL USE | JANOSKO, CHASITY PAIGE | 271d overdue |
| 18127284 | COMPOSITIONS AND METHODS FOR PRODUCING AND USING ILCS TO TREAT HEALTH CONDITIONS | HAMA, JOANNE | 131d overdue |
| 17317717 | VENOUS ACCESS CATHETERS AND METHODS FOR PORTAL VENOUS SYSTEM CATHETERIZATION | PAZ ESTEVEZ, GUILLERMO G | 128d overdue |
| 17501148 | VENOUS ACCESS CATHETERS AND METHODS FOR PORTAL VENOUS SYSTEM CATHETERIZATION | PAZ ESTEVEZ, GUILLERMO G | 114d overdue |
| 17962656 | Toll-Like Receptor 8 (TLR8)-Specific Antagonists and Methods of Making and Uses Thereof | SEAMAN, D MARGARET M | 60d overdue |
| 18132164 | COMPOSITIONS, METHODS AND USES FOR IN VITRO AND IN VIVO GENERATION OF FUNCTIONAL THYMIC TISSUE | WILSON, MICHAEL C | 45d overdue |
| 17511228 | GENERATION OF FUNCTIONAL AND PATIENT-SPECIFIC THYMIC TISSUE FROM INDUCED PLURIPOTENT STEM CELLS | SCHULTZ, JAMES | 4d overdue |
| 17619579 | METHOD OF CONTROLLING AN AMOUNT OF SOLUBLE BASE CONTENT OF MATERIAL COMPRISING LITHIUM CARBONATE AND STRUCTURE, CATHODE, AND BATTERY FORMED USING THE METHOD | MCCLURE, CHRISTINA D | 1d overdue |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 7 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17619579 | METHOD OF CONTROLLING AN AMOUNT OF SOLUBLE BASE CONTENT OF MATERIAL COMPRISING LITHIUM CARBONATE AND STRUCTURE, CATHODE, AND BATTERY FORMED USING THE METHOD | MCCLURE, CHRISTINA D | 1d overdue |
| 18096668 | ELECTRON-ENHANCED ATOMIC LAYER DEPOSITION (EE-ALD) METHODS AND DEVICES PREPARED BY SAME | MCCLURE, CHRISTINA D | 56d |
| 19143905 | SURGICAL INSTRUMENT FOR CONDITIONING LARGE DIAMETER BURR HOLES | SHIRSAT, MARCELA | — |
| 18972502 | FLOATING PLATFORM SYSTEM FOR MECHANICAL TESTING OF GELS AND TISSUES | HUANG, DAVID Z | — |
| 18967837 | Proteins for Blocking Neurotransmitter Release | SWIFT, CANDICE LEE | — |
| 18863566 | IMMUNOBIOTICS FOR PREVENTING BACTERIAL PNEUMONIA AND METHODS OF USING THE SAME | OGUNBIYI, OLUWATOSIN A | — |
| 18863013 | THERMOPHOTOVOLTAIC SYSTEM | BUCK, LINDSEY A | — |
| Art Unit | Apps |
|---|---|
| 3783 | 4 |
| 1631 | 3 |
| 3792 | 2 |
| 1681 | 2 |
| 3791 | 2 |
| 1613 | 2 |
| 1647 | 2 |
| 1646 | 2 |
| 3774 | 2 |
| 1682 | 2 |
| App # | Title | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|
| 19143905 | SURGICAL INSTRUMENT FOR CONDITIONING LARGE DIAMETER BURR HOLES | SHIRSAT, MARCELA | 3775 | §102§103 | Final Rejection | — | Pending | Jun 27, 2025 |
| 19178366 | OPTIMIZED VIRTUAL REALITY SYSTEM | LEE, SARAH YEO | 2616 | §103 | Non-Final OA | — | Pending | Apr 14, 2025 |
| 19057550 | Scanner Utilizing Beam Computed Tomography And Antiscatter Grid | KIM, KIHO | 2884 | §102§103 | Non-Final OA | — | Pending | Feb 19, 2025 |
| 18972502 | FLOATING PLATFORM SYSTEM FOR MECHANICAL TESTING OF GELS AND TISSUES | HUANG, DAVID Z | 2855 | §112 | Non-Final OA | — | Pending | Dec 06, 2024 |
| 18967837 | Proteins for Blocking Neurotransmitter Release | SWIFT, CANDICE LEE | — | §103§112Other | Non-Final OA | — | Pending | Dec 04, 2024 |
| 18864247 | ANTIBIOTIC COMPOSITION AND METHODS OF USE THEREOF | SEAMAN, D MARGARET M | 1629 | §103 | Non-Final OA | — | Pending | Nov 08, 2024 |
| 18863566 | IMMUNOBIOTICS FOR PREVENTING BACTERIAL PNEUMONIA AND METHODS OF USING THE SAME | OGUNBIYI, OLUWATOSIN A | 1645 | §102§103§112 | Non-Final OA | — | Pending | Nov 06, 2024 |
| 18863013 | THERMOPHOTOVOLTAIC SYSTEM | BUCK, LINDSEY A | 1728 | §102§103§112 | Final Rejection | — | Pending | Nov 05, 2024 |
| 18925427 | HUMAN OSTEOPONTIN PROTEIN PRODUCTION IN PLANT SYSTEMS | SHEN, YANXIN NMN | 1663 | §103§112 | Non-Final OA | 9d | Pending | Oct 24, 2024 |
| 18920752 | METHODS AND DEVICES FOR A CONFIGURABLE MEDICAL INFORMATION PLATFORM | YEN, SYLING | 3687 | §103 | Non-Final OA | — | Pending | Oct 18, 2024 |
| 18847671 | METHODS AND COMPOSITIONS FOR DISRUPTING TAU AGGREGATES USING POLYSERINE REPEAT SEQUENCES TARGETING EXOGENOUS PROTEINS | SAIDHA, TEKCHAND | 1652 | §102§112 | Non-Final OA | — | Pending | Sep 16, 2024 |
| 18885581 | Inter-Frequency Signal Aiding For Tracking Satellite Navigation Signals | GREGORY, BERNARR E | 3648 | §101§103§112 | Non-Final OA | — | Pending | Sep 14, 2024 |
| 18817015 | VENTRICULAR ASSIST ASSEMBLY, SYSTEM, AND METHOD | CIRULNICK, EMILY NICOLE | 3792 | §102§103§112Other | Non-Final OA | — | Pending | Aug 27, 2024 |
| 18839131 | SMALL MOLECULES TARGETTING EIF3E TO INHIBIT TUMOR GROWTH PROGRESSION, AND METASTASIS | AULAKH, CHARANJIT | 1621 | §102§112 | Non-Final OA | — | Pending | Aug 16, 2024 |
| 18800335 | SYNTHESIS OF BACKBONE MODIFIED MORPHOLINO OLIGONUCLEOTIDES AND CHIMERAS USING PHOSPHORAMIDITE CHEMISTRY | RILEY, JEZIA | 1681 | §102§103§112Other | Non-Final OA | — | Pending | Aug 12, 2024 |
| 18837842 | PLASMON-ENHANCED FLUORESCENCE BIOCHEMICAL SENSORS | EOM, ROBERT J | 1797 | §103 | Non-Final OA | 20d | Pending | Aug 12, 2024 |
| 18784462 | DEVICES FOR IMPLANTATION OF CELLULAR TRANSPLANTS AND METHODS OF USING THE SAME | MULLINS, JESSICA LYNN | 3792 | §102§103§112 | Non-Final OA | — | Pending | Jul 25, 2024 |
| 18750876 | RHEOLOGICALLY MODIFIED LIQUID METAL DEVICES AND RELATED SYSTEMS AND METHODS | SMOOT, MORIAH SIMONE MCMIL | 3791 | §102§103§112 | Non-Final OA | — | Pending | Jun 21, 2024 |
| 18734972 | FIBROUS POLYPEPTIDE-BASED BIOSCAFFOLD DELIVERY OF THERAPEUTICS TO NEURAL CELLS | CHI, AMANDA LYNN | 1613 | §102§103§112 | Non-Final OA | — | Pending | Jun 05, 2024 |
| 18648678 | METHODS AND COMPOSITIONS TO ENHANCE THE ANTI-INFLAMMATORY EFFECTS OF INTERLEUKIN 10 | NOBLE, MARCIA STEPHENS | 1632 | §103§112 | Non-Final OA | — | Pending | Apr 29, 2024 |
| 18703245 | METHOD AND REACTOR SYSTEM FOR SPLITTING WATER AND/OR CARBON DIOXIDE | HENDRICKSON, STUART L | — | §112Other | Non-Final OA | — | Pending | Apr 19, 2024 |
| 18627155 | COMPOSITIONS AND METHODS FOR REDUCING ADVERSE EFFECTS OF STORAGE, TRANSPORT AND ADMINISTRATION OF ANTIGEN-CONTAINING FORMULATIONS | ZHANG SPIERING, DONGXIU | 1616 | §103§112 | Non-Final OA | — | Pending | Apr 04, 2024 |
| 18627309 | CELLULAR TRANSPLANT CARRIER DEVICES AND METHODS OF USING THE SAME | GRAY, PHILLIP A | 3783 | §102§103§112 | Non-Final OA | — | Pending | Apr 04, 2024 |
| 18697411 | DIAGNOSING MULTIPLE SCLEROSIS (MS) | COLE, HOUSTON DAVID | 1758 | §101§102§103§112 | Non-Final OA | — | Pending | Mar 29, 2024 |
| 18622525 | COMPOSITIONS AND METHODS FOR REDUCED TOXICITY IN TRANSPLANTATION USING JANUS KINASE (JAK) INHIBITORS | PYLA, EVELYN Y | 1633 | §102§103§112 | Non-Final OA | — | Pending | Mar 29, 2024 |
| 18601079 | LIGHTWEIGHT CALIBRATION METHOD FOR DIRECTION FINDING | QUIGLEY, KYLE ROBERT | 2857 | §103 | Final Rejection | — | Pending | Mar 11, 2024 |
| 18686115 | IONIC LIQUID-BASED COMPOSITE MEMBRANES USING FUNCTIONAL CROSS-LINKERS | EZELUOMBA, MIRIAM NCHEKWUBECHU | 1776 | §103§112 | Non-Final OA | — | Pending | Feb 23, 2024 |
| 18585791 | Crystalline Sp-Sp2 Hybridized Carbon Allotropes through Dynamic Covalent Synthesis | KUMAR, SRILAKSHMI K | 1738 | §102§112 | Non-Final OA | — | Pending | Feb 23, 2024 |
| 18685045 | CELL-SURFACE ANTIBODY TO A SPECIFIC BIOMARKER OF PANCREATIC BETA-CELLS | LOCKARD, JON MCCLELLAND | 1647 | §112 | Non-Final OA | — | Pending | Feb 20, 2024 |
| 18293258 | Dynamic Assessment Of Airway Deformation | AZIMA, SHAGHAYEGH | 2671 | §103 | Non-Final OA | 23d | Pending | Jan 29, 2024 |
| 18412205 | REVERSE THERMAL GELS AND THEIR USE AS VASCULAR EMBOLIC REPAIR AGENTS | PIPIC, ALMA | 1617 | §103§112 | Final Rejection | — | Pending | Jan 12, 2024 |
| 18396386 | SURFACE BRACHYTHERAPY DEVICE, APPLICATOR, AND METHODS THEREFOR | CASLER, BRIAN L | 3791 | §102§103 | Non-Final OA | — | Pending | Dec 26, 2023 |
| 18573907 | PEROXIDE-ENHANCED GERMICIDAL IRRADIATION FOR THE TREATMENT OF AIRBORNE AND SURFACE-ASSOCIATED CONTAMINANTS | CHEN, CHANGRU | 1796 | §103 | Final Rejection | 12d | Pending | Dec 22, 2023 |
| 18562035 | COMPOSITIONS AND METHODS FOR PRODUCING AND USING CELL-BASED IMMUNOTHERAPIES TO TARGET TUMORS | HOLTZMAN, KATHERINE ANN | 1646 | §102§103§112 | Non-Final OA | — | Pending | Nov 17, 2023 |
| 18506637 | COMPOSITIONS AND METHODS OF USE FOR MUTATED HOTAIR IN THE TREATMENT OF CANCERS | KONOPKA, CATHERINE ANNE | 1635 | §112 | Non-Final OA | — | Pending | Nov 10, 2023 |
| 18481830 | SULCUS IMPLANTS AND METHODS OF USING THE SAME | LOPEZ, LESLIE ANN | 3774 | §102 | Final Rejection | 83d | Pending | Oct 05, 2023 |
| 18375953 | CLUTCH SYSTEM FOR A POWERED PROSTHETIC DEVICE | CROWE, RAEGAN NADIA | 3774 | §102 | Non-Final OA | — | Pending | Oct 02, 2023 |
| 18285246 | CEMENT ADDITIVE FOR RETARDATION OF CEMENT HYDRATION, CEMENT MIXTURES INCLUDING SAME, AND METHODS OF FORMING AND USING SAME | CHAU, LISA N | 1785 | §102§103§112 | Non-Final OA | — | Pending | Sep 30, 2023 |
| 18279769 | METHODS AND DEVICES FOR NUCLEIC ACID DETECTION | JONES, CHRISTINE MICHELLE | 1682 | §103 | Final Rejection | 13d | Pending | Sep 01, 2023 |
| 18237705 | COMPOSITIONS AND METHODS FOR IMPROVED TREATMENT OF PLATINUM-BASED CHEMOTHERAPEUTIC RESISTANT TUMORS | LEE, WILLIAM Y | 1623 | §102§112 | Non-Final OA | — | Pending | Aug 24, 2023 |
| 18359793 | Novel Peptide Carrier Compositions | BANERJEE, KOYELI | 1658 | §103 | Non-Final OA | — | Pending | Jul 26, 2023 |
| 18359810 | Microfluidics Chips Useful in Nanoparticle Preparation and Expandable Pump Network System Useful Therewith | GORDON, BRIAN R | 1798 | §102§103§112 | Final Rejection | 76d | Pending | Jul 26, 2023 |
| 18271727 | METHODS AND COMPOSITIONS FOR MOLECULAR TRACKING IN INDIVIDUAL CELLS IN VIVO | YOUNG, BRIAN ELLIS | 1682 | §102§103§112 | Non-Final OA | — | Pending | Jul 11, 2023 |
| 18267348 | COMPOSITION FOR REVERSIBLE POLYMERIZATION OF THIOESTER AND METHODS THEREOF | KAHN, RACHEL | 1766 | §103§112 | Final Rejection | — | Pending | Jun 14, 2023 |
| 18318926 | HYBRID POLYMER/CRYSTAL PHOTOMECHANICAL MATERIALS | ANGEBRANNDT, MARTIN J | 1737 | §103§112 | Non-Final OA | 56d | Pending | May 17, 2023 |
| 18298967 | PULSED ELECTRODEPOSITION FOR REVERSIBLE METAL ELECTRODEPOSITION TO CONTROL METAL FILM MORPHOLOGY AND OPTICAL PROPERTIES | DOWNES, NATHANAEL JASON | 1794 | §103§112 | Non-Final OA | — | Pending | Apr 11, 2023 |
| 18132164 | COMPOSITIONS, METHODS AND USES FOR IN VITRO AND IN VIVO GENERATION OF FUNCTIONAL THYMIC TISSUE | WILSON, MICHAEL C | 1638 | §102§112Other | Final Rejection | 45d overdue | Pending | Apr 07, 2023 |
| 18127284 | COMPOSITIONS AND METHODS FOR PRODUCING AND USING ILCS TO TREAT HEALTH CONDITIONS | HAMA, JOANNE | 1647 | §101§103§112 | Non-Final OA | 131d overdue | Pending | Mar 28, 2023 |
| 18175225 | METHOD OF TREATMENT OF PATIENTS HAVING REDUCED SENSITIVITY TO A BCL-2 INHIBITOR | KAUFMAN, CLAIRE M | 1674 | §102§103§112Other | Non-Final OA | — | Pending | Feb 27, 2023 |
| 18042509 | ULTRAVIOLET-ABSORPTIVE NANOPARTICLES AND MICROPARTICLES FOR INTRADERMAL USE | JANOSKO, CHASITY PAIGE | 1613 | §103§112 | Final Rejection | 271d overdue | Pending | Feb 22, 2023 |
IP Author helps IP teams respond to office actions faster with AI-generated responses, examiner analytics, and prosecution intelligence.
Start Free TrialThe Regents of the University of Colorado has 73 pending office actions as of October 2026, spread across 57 art units and 69 examiners.
Guillermo G Paz Estevez has the most, with 3 of The Regents of the University of Colorado's pending office actions.
Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.
