Prosecution Insights
Last updated: May 29, 2026

Vertex Pharmaceuticals Incorporated

12 pending office actions • 11 art units • 12 examiners • 0 of 12 (0%) have an AI response strategy ready • 31 patents granted in the last 365 days

Portfolio Summary

12
Total Pending OAs
9
Non-Final OAs
3
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 12 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

8
Overdue
1
Due this week
2
Due this month
0
Due in next 60 days
1
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 12 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (8)Due ≤ 7 days (1)Due ≤ 30 days (2)Due later (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

0
Hard (0%)
6
Medium (50%)
2
Easy (17%)
4
Unknown (33%)

Rejection Statute Mix

BucketCases
§103 only4 (33%)
§102 only1 (8%)
§112 only2 (17%)
Double-patenting + other1 (8%)
No statute on record4 (33%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

12
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

120 h
Manual time on pending OAs
24 h
Time saved (low, 20%)
42 h
Time saved (mid, 35%)
1.1 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
DICKINSON, PAUL W 1 63.0% +9.5%
RAO, PADMAJA S 1 69.5% +35.9%
CORDAS, EMILY ANN 1 50.6% +58.5%
FETTEROLF, BRANDON J 1 49.5% +14.6%
VISHNYAKOVA, ELENA VLADIMIROVNA 1 59.3% +73.3%
ROGERS, ERIC JASON 1 59.2% +28.6%
O DELL, DAVID K 1 57.8% +35.8%
HOWELL, THEODORE R 1 66.8% +25.4%
BATES, KEENAN ALEXANDER 1 46.3% +70.8%
NGUYEN, NGHI V 1 53.6% +50.4%

Interview Candidates (9)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17560680 ENHANCED DIFFERENTIATION OF BETA CELLS NGUYEN, NGHI V 86d overdue
18566176 SOLID DOSAGE FORMS AND DOSING REGIMENS COMPRISING (2R,3S,4S,5R)-4-[[3-(3,4-DIFLUORO-2-METHOXY-PHENYL)-4,5-DIMETHYL-5-(TRIFLUOROMETHYL) TETRAHYDROFURAN-2-CARBONYL]AMINO]PYRIDINE-2-CARBOXAMIDE RAO, PADMAJA S 52d overdue
17669874 PANCREATIC DIFFERENTIATION BATES, KEENAN ALEXANDER 37d overdue
17916484 INDOLE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD) O DELL, DAVID K 31d overdue
17820773 METHOD FOR TREATING CANCER USING A COMBINATION OF DNA DAMAGING AGENTS AND ATR INHIBITORS HOWELL, THEODORE R 25d overdue
18030518 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VISHNYAKOVA, ELENA VLADIMIROVNA 7d
18248068 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR FETTEROLF, BRANDON J 28d
18018787 IN VITRO DIFFERENTIATION OF PANCREATIC ENDOCRINE CELLS ROGERS, ERIC JASON 28d

Top Art Units

Art UnitApps
1626 2
1618 1
1627 1
1632 1
1691 1
1638 1
1621 1
1628 1
1631 1
1653 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18647137 STEM CELL DERIVED PANCREATIC ISLET DIFFERENTIATION DICKINSON, PAUL W 1618 §103 Non-Final OA 26d overdue Pending Apr 26, 2024
18566176 SOLID DOSAGE FORMS AND DOSING REGIMENS COMPRISING (2R,3S,4S,5R)-4-[[3-(3,4-DIFLUORO-2-METHOXY-PHENYL)-4,5-DIMETHYL-5-(TRIFLUOROMETHYL) TETRAHYDROFURAN-2-CARBONYL]AMINO]PYRIDINE-2-CARBOXAMIDE RAO, PADMAJA S 1627 Other Non-Final OA 52d overdue Pending Dec 01, 2023
18281154 STEM CELL DIFFERENTIATION AND POLYMERS CORDAS, EMILY ANN 1632 DPOther Non-Final OA 71d Pending Sep 08, 2023
18248068 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR FETTEROLF, BRANDON J 1626 §112 Final Rejection 28d Pending Apr 06, 2023
18030518 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VISHNYAKOVA, ELENA VLADIMIROVNA 1691 §103 Non-Final OA 7d Pending Apr 06, 2023
18018787 IN VITRO DIFFERENTIATION OF PANCREATIC ENDOCRINE CELLS ROGERS, ERIC JASON 1638 §102 Non-Final OA 28d Pending Jan 30, 2023
17916484 INDOLE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD) O DELL, DAVID K 1621 Other Non-Final OA 31d overdue Pending Sep 30, 2022
17820773 METHOD FOR TREATING CANCER USING A COMBINATION OF DNA DAMAGING AGENTS AND ATR INHIBITORS HOWELL, THEODORE R 1628 Other Non-Final OA 25d overdue Pending Aug 18, 2022
17669874 PANCREATIC DIFFERENTIATION BATES, KEENAN ALEXANDER 1631 §112 Final Rejection 37d overdue Pending Feb 11, 2022
17560680 ENHANCED DIFFERENTIATION OF BETA CELLS NGUYEN, NGHI V 1653 §103 Non-Final OA 86d overdue Pending Dec 23, 2021
17345256 INHIBITORS OF APOL1 AND METHODS OF USING SAME CHICKS, ASHLI ARIANA 1626 Other Non-Final OA 18d overdue Pending Jun 11, 2021
16845280 GENE-EDITING SYSTEMS FOR MODIFYING A SCN9A OR SCN10A GENE AND METHODS OF USE THEREOF SHIN, DANA H 1635 §103 Final Rejection 49d overdue Pending Apr 10, 2020

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