Prosecution Insights
Last updated: August 16, 2026

Vertex Pharmaceuticals Incorporated

20 pending office actions • 14 art units • 20 examiners • 0 of 20 (0%) have an AI response strategy ready • 25 patents granted in the last 365 days

Portfolio Summary

20
Total Pending OAs
12
Non-Final OAs
8
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 6 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

3
Overdue
1
Due this week
1
Due this month
0
Due in next 60 days
1
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 6 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (3)Due ≤ 7 days (1)Due ≤ 30 days (1)Due later (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

3
Hard (15%)
10
Medium (50%)
7
Easy (35%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§103 only3 (15%)
§102 only2 (10%)
§112 only3 (15%)
Double-patenting only4 (20%)
Double-patenting + other5 (25%)
Multi-statute (no §101)3 (15%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

17
Life Sciences
85% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
3
Business / Other
15% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

200 h
Manual time on pending OAs
40 h
Time saved (low, 20%)
70 h
Time saved (mid, 35%)
1.8 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
KRINOS, EMILY LYNN 1
PALENIK, JEFFREY T 1 53.8% +26.8%
CHANDRAKUMAR, NIZAL S 1 72.7% +18.3%
DAVIS, BRIAN J 1 84.8% -4.1%
RAHMANI, NILOOFAR 1 77.5% -3.1%
DICKINSON, PAUL W 1 62.8% +9.9%
HEES, OLIVER DRAGON 1 100.0% +0.0%
CORDAS, EMILY ANN 1 50.4% +58.1%
TOWNSLEY, SARA ELIZABETH 1 24.9% +48.9%
MARTIN, KEVIN STEPHEN 1 75.8% +24.5%

Quick Wins (2)

Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 2 ordered by deadline are shown.

App #TitleExaminerDue in
18794848 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR DAVIS, BRIAN J
18566297 SUBSTITUTED TETRAHYDROFURAN-2-CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS HEES, OLIVER DRAGON

Hard Cases (4)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 4 ordered by deadline are shown.

App #TitleExaminerDue in
17669874 PANCREATIC DIFFERENTIATION BATES, KEENAN ALEXANDER 37d overdue
19100776 COMPOSITIONS FOR THE TREATMENT OF CFTR-MEDIATED DISEASES KRINOS, EMILY LYNN
18305186 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN TOWNSLEY, SARA ELIZABETH
18162129 CELL THERAPY FOR DIABETES MONTANARI, DAVID A

Interview Candidates (5)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 5 ordered by deadline are shown.

App #TitleExaminerDue in
18281154 STEM CELL DIFFERENTIATION AND POLYMERS CORDAS, EMILY ANN 71d
18999125 PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF PALENIK, JEFFREY T
18836681 SPIRO PIPERIDINE DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME CHANDRAKUMAR, NIZAL S
18305186 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN TOWNSLEY, SARA ELIZABETH
18030520 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MARTIN, KEVIN STEPHEN

Top Art Units

Art UnitApps
1632 2
1691 2
1638 2
1615 1
1614 1
1618 1
1628 1
1629 1
1624 1
1626 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
19100776 COMPOSITIONS FOR THE TREATMENT OF CFTR-MEDIATED DISEASES KRINOS, EMILY LYNN 1615 §102§103§112 Non-Final OA Pending Feb 03, 2025
18999125 PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF PALENIK, JEFFREY T DP Non-Final OA Pending Dec 23, 2024
18836681 SPIRO PIPERIDINE DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME CHANDRAKUMAR, NIZAL S §103§112DP Non-Final OA Pending Aug 07, 2024
18794848 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR DAVIS, BRIAN J 1614 §112 Non-Final OA Pending Aug 05, 2024
18775146 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR RAHMANI, NILOOFAR §112DP Non-Final OA Pending Jul 17, 2024
18647137 STEM CELL DERIVED PANCREATIC ISLET DIFFERENTIATION DICKINSON, PAUL W 1618 §103 Final Rejection 26d overdue Pending Apr 26, 2024
18566297 SUBSTITUTED TETRAHYDROFURAN-2-CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS HEES, OLIVER DRAGON 1628 §112DP Non-Final OA Pending Dec 01, 2023
18281154 STEM CELL DIFFERENTIATION AND POLYMERS CORDAS, EMILY ANN 1632 §102§103§112DPOther Non-Final OA 71d Pending Sep 08, 2023
18305186 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN TOWNSLEY, SARA ELIZABETH 1629 §102 Final Rejection Pending Apr 21, 2023
18030520 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MARTIN, KEVIN STEPHEN 1624 §112 Non-Final OA Pending Apr 06, 2023
18030518 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VISHNYAKOVA, ELENA VLADIMIROVNA 1691 §103 Final Rejection 7d Pending Apr 06, 2023
18030519 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR KUCKLA, ANNA GRACE 1626 §102 Final Rejection Pending Apr 06, 2023
18162129 CELL THERAPY FOR DIABETES MONTANARI, DAVID A 1632 §102§103§112Other Non-Final OA Pending Jan 31, 2023
18018787 IN VITRO DIFFERENTIATION OF PANCREATIC ENDOCRINE CELLS ROGERS, ERIC JASON 1638 §103 Final Rejection 28d Pending Jan 30, 2023
17916484 INDOLE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD) O DELL, DAVID K 1621 DP Final Rejection 31d overdue Pending Sep 30, 2022
17669874 PANCREATIC DIFFERENTIATION BATES, KEENAN ALEXANDER 1631 §102§103 Non-Final OA 37d overdue Pending Feb 11, 2022
17469665 Compositions and Methods for Treatment of Duchenne Muscular Dystrophy TATGE, LEXUS MARC 1600 §103DP Non-Final OA Pending Sep 08, 2021
17339425 GENE-EDITING SYSTEMS FOR EDITING A CYSTIC FIBROSIS TRANSMEMBRANE REGULATOR (CFTR) GENE JOHNSON, ALLISON MARIE 1638 §112 Non-Final OA Pending Jun 04, 2021
17293632 METHODS OF TREATMENT FOR CYSTIC FIBROSIS LEE, HOI YAN NMN 1693 DP Final Rejection Pending May 13, 2021
17122543 GCN2 INHIBITORS AND USES THEREOF LEE, ANDREW P 1691 DP Final Rejection Pending Dec 15, 2020

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