Prosecution Insights
Last updated: October 01, 2026

William Marsh Rice University

Technology areas: Biotechnology & Pharmaceuticals • Chemistry & Materials

28 pending office actions • 20 art units • 28 examiners • 0 of 28 (0%) have an AI response strategy ready • 30 patents granted in the last 365 days

Analysis

William Marsh Rice University currently has 27 pending office actions within the Biotechnology & Pharmaceuticals technology area. These actions are distributed across 27 distinct examiners, meaning that every pending case is being reviewed by a different individual. Furthermore, the portfolio spans 19 distinct art units, reflecting a high degree of technical diversity within the life sciences sector.

NGUYEN, DUNE NGOC is identified as the busiest examiner with 1 pending case. This indicates that there is no concentration of work under any single examiner, as the busiest examiner's workload matches the single-case-per-examiner trend seen across the 27 distinct examiners. For practitioners, this means that every one of the 27 pending office actions requires a unique approach tailored to a specific examiner's tendencies and the particular requirements of 19 different art units.

The breadth of 19 distinct art units suggests that the university's research covers a wide array of biological and pharmaceutical sub-disciplines. Managing such a fragmented portfolio requires significant coordination, as there are no opportunities to leverage a relationship with a single examiner to resolve multiple cases. The practitioner must be prepared to navigate the distinct procedural nuances of 19 different technical groups while addressing the specific legal and technical arguments raised by 27 different examiners within the Biotechnology & Pharmaceuticals area.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

28
Total Pending OAs
17
Non-Final OAs
8
Final Rejections
3
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 11 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

6
Overdue
0
Due this week
4
Due this month
0
Due in next 60 days
1
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 11 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (6)Due ≤ 30 days (4)Due later (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

19
Hard (68%)
8
Medium (29%)
1
Easy (4%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other5 (18%)
§103 only6 (21%)
Double-patenting only1 (4%)
Double-patenting + other2 (7%)
Multi-statute (no §101)14 (50%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

17
Life Sciences
61% of docket
2
Information Tech
7% of docket
1
Communications
4% of docket
0
Semiconductors
0% of docket
2
Mechanical / Eng
7% of docket
6
Business / Other
21% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

280 h
Manual time on pending OAs
56 h
Time saved (low, 20%)
98 h
Time saved (mid, 35%)
2.5 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
NGUYEN, DUNE NGOC 1 — —
SAMARA, HUSAM TURKI 1 55.7% +17.6%
WHITE, SADIE 1 48.8% +31.6%
NASSIRI MOTLAGH, ANITA 1 55.9% +24.6%
NGUYEN, CAO H 1 90.9% +7.4%
AMIN, MUSTAFA A 1 64.1% +29.9%
GILLIARD, DELOMIA L 1 89.6% +10.4%
BAUM, ZACHARY JOHN 1 81.5% +14.9%
ZAHORIK, AMANDA MARY 1 57.8% +49.0%
BERHANU, ETSUB D 1 65.3% +24.8%

Quick Wins (1)

Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
18905992 FLUIDICALLY PROGRAMMED WEARABLE HAPTIC DEVICES NGUYEN, CAO H —

Hard Cases (19)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18557747 COMPOSITIONS AND METHODS FOR CHIMERIC AMPLICON FORMATION SALMON, KATHERINE D 28d overdue
18182924 System and Method for Low-Rank Tensor Decomposition with Neural Network Priors PHAM, JESSICA THUY 17d overdue
18003412 AMPLICON COMPREHENSIVE ENRICHMENT BERTAGNA, ANGELA MARIE 3d overdue
18871122 SOLUTION-PROCESSED PEROVSKITE HETEROSTRUCTURES WHITE, SADIE 15d
18118834 ANODES, CATHODES, AND SEPARATORS FOR BATTERIES AND METHODS TO MAKE AND USE SAME CARRICO, ROBERT SCOTT 26d
19195045 Private and Decentralized 3D from Crowd Sourced Image Data NGUYEN, DUNE NGOC —
18863937 FLASH JOULE HEATING FOR PRODUCTION OF 1D CARBON AND/OR BORON NITRIDE NANOMATERIALS NASSIRI MOTLAGH, ANITA —
18778478 METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR PROVIDING AND USING SHUFFLE TEMPLATES TO DISTRIBUTE DATA AMONG WORKERS COMPRISING COMPUTE RESOURCES IN A DATA CENTER AMIN, MUSTAFA A —

Interview Candidates (8)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18871122 SOLUTION-PROCESSED PEROVSKITE HETEROSTRUCTURES WHITE, SADIE 15d
19067354 METHODS AND SYSTEMS FOR OPERATING LARGE LANGUAGE MODELS USING SINGLE-INSTRUCTION-MULTIPLE-DATA REGISTERS SAMARA, HUSAM TURKI 70d
18863937 FLASH JOULE HEATING FOR PRODUCTION OF 1D CARBON AND/OR BORON NITRIDE NANOMATERIALS NASSIRI MOTLAGH, ANITA —
18778478 METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR PROVIDING AND USING SHUFFLE TEMPLATES TO DISTRIBUTE DATA AMONG WORKERS COMPRISING COMPUTE RESOURCES IN A DATA CENTER AMIN, MUSTAFA A —
18737264 NEURAL WAVEFRONT SHAPING FOR GUIDESTAR-FREE IMAGING THROUGH AN OBSCURANT GILLIARD, DELOMIA L —
18735513 Synthesis of Metallic Glass Nanoparticles by Flash Carbothermic Reactions and Compositions Thereof BAUM, ZACHARY JOHN —
18667652 NON-INVASIVE SITE-SPECIFIC MEASUREMENT OF TRANSGENE EXPRESSION IN THE BRAIN ZAHORIK, AMANDA MARY —
18665034 RAPID SAMPLING OF INTERSTITIAL FLUID USING A MICRONEEDLE ARRAY AND VACCUM-ASSISTED SKIN PATCH BERHANU, ETSUB D —

Top Art Units

Art UnitApps
1681 2
1600 2
2161 1
1721 1
2661 1
1732 1
3791 1
1612 1
1682 1
1728 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
19195045 Private and Decentralized 3D from Crowd Sourced Image Data NGUYEN, DUNE NGOC — §103§112 Non-Final OA — Pending Apr 30, 2025
19067354 METHODS AND SYSTEMS FOR OPERATING LARGE LANGUAGE MODELS USING SINGLE-INSTRUCTION-MULTIPLE-DATA REGISTERS SAMARA, HUSAM TURKI 2161 §103 Non-Final OA 70d Pending Feb 28, 2025
18871122 SOLUTION-PROCESSED PEROVSKITE HETEROSTRUCTURES WHITE, SADIE 1721 §102§103§112 Non-Final OA 15d Pending Dec 02, 2024
18863937 FLASH JOULE HEATING FOR PRODUCTION OF 1D CARBON AND/OR BORON NITRIDE NANOMATERIALS NASSIRI MOTLAGH, ANITA — §102§103§112 Non-Final OA — Pending Nov 07, 2024
18905992 FLUIDICALLY PROGRAMMED WEARABLE HAPTIC DEVICES NGUYEN, CAO H — §103 Non-Final OA — Pending Oct 03, 2024
18778478 METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR PROVIDING AND USING SHUFFLE TEMPLATES TO DISTRIBUTE DATA AMONG WORKERS COMPRISING COMPUTE RESOURCES IN A DATA CENTER AMIN, MUSTAFA A — §101§103 Non-Final OA — Pending Jul 19, 2024
18737264 NEURAL WAVEFRONT SHAPING FOR GUIDESTAR-FREE IMAGING THROUGH AN OBSCURANT GILLIARD, DELOMIA L 2661 §102§103 Non-Final OA — Pending Jun 07, 2024
18735513 Synthesis of Metallic Glass Nanoparticles by Flash Carbothermic Reactions and Compositions Thereof BAUM, ZACHARY JOHN 1732 §102§103§112 Non-Final OA — Pending Jun 06, 2024
18667652 NON-INVASIVE SITE-SPECIFIC MEASUREMENT OF TRANSGENE EXPRESSION IN THE BRAIN ZAHORIK, AMANDA MARY — §103§112Other Non-Final OA — Pending May 17, 2024
18665034 RAPID SAMPLING OF INTERSTITIAL FLUID USING A MICRONEEDLE ARRAY AND VACCUM-ASSISTED SKIN PATCH BERHANU, ETSUB D 3791 §102§103§112 Non-Final OA — Pending May 15, 2024
18703201 METHODS OF USE AND ADMINISTRATION OF ENCAPSULATED CELLS KELLY, ROBERT M — §103§112 Non-Final OA — Pending Apr 19, 2024
18293734 IDENTIFICATION OF PRO- AND ANTI-INFLAMMATORY LIPIDS RELATING TO IMMUNE RESPONSE TO MEDICAL IMPLANTS MAEWALL, SNIGDHA 1612 §102§103 Non-Final OA — Pending Jan 30, 2024
18557747 COMPOSITIONS AND METHODS FOR CHIMERIC AMPLICON FORMATION SALMON, KATHERINE D 1682 §101§102 Final Rejection 28d overdue Pending Oct 27, 2023
18264646 FLASH RECYCLING OF BATTERIES HORNSBY, BARTHOLOMEW ANDREW 1728 §103§112 Non-Final OA — Pending Aug 08, 2023
18258550 IMPLANTABLE CONSTRUCTS FOR MODULATING AN IMMUNE RESPONSE CHEONG, CHEOM-GIL 1645 DP Non-Final OA 9d Pending Jun 20, 2023
18246451 ULTRAFAST FLASH JOULE HEATING SYNTHESIS METHODS AND SYSTEMS FOR PERFORMING SAME FIGUEROA, JOHN J 1763 §103 Non-Final OA — Pending Mar 23, 2023
18182924 System and Method for Low-Rank Tensor Decomposition with Neural Network Priors PHAM, JESSICA THUY 2121 §101§102§103§112 Final Rejection 17d overdue Pending Mar 13, 2023
18118834 ANODES, CATHODES, AND SEPARATORS FOR BATTERIES AND METHODS TO MAKE AND USE SAME CARRICO, ROBERT SCOTT 1727 §102§112 Non-Final OA 26d Pending Mar 08, 2023
18109457 VARIABLE FREQUENCY DRIVE FOR FLASH JOULE HEATING SYSTEM AND METHOD BELAY, DILNESSA B 1736 §102§103§112 Non-Final OA — Pending Feb 14, 2023
18168401 3D PRINTED SILICA WITH NANOSCALE RESOLUTION MACHNESS, ARIELLA 1743 §103 Final Rejection 23d overdue Pending Feb 13, 2023
18003412 AMPLICON COMPREHENSIVE ENRICHMENT BERTAGNA, ANGELA MARIE 1681 §101§103§112 Final Rejection 3d overdue Pending Dec 27, 2022
17999960 NON-EXTENSIBLE OLIGONUCLEOTIDES IN DNA AMPLIFICATION REACTIONS CASH, KAILEY ELIZABETH 1683 §102§103§112 Non-Final OA — Pending Nov 28, 2022
17997696 QUANTITATIVE BLOCKER DISPLACEMENT AMPLIFICATION (QBDA) SEQUENCING FOR CALIBRATION-FREE AND MULTIPLEXED VARIANT ALLELE FREQUENCY QUANTITATION PRIEST, AARON A 1681 §103DP Final Rejection 43d overdue Pending Nov 01, 2022
17972053 GREEN HIGH STRENGTH CEMENT GUINO-O UZZLE, MARITES A 1731 §103 Non-Final OA 2d overdue Pending Oct 24, 2022
17773572 ENGINEERED CELLS FOR CONTROLLED PRODUCTION BRETZ, COREY LANE 1600 §101§103 Non-Final OA — Pending Apr 29, 2022
17054312 PROXIMITY INDUCED SITE-SPECIFIC ANTIBODY CONJUGATION VAN DRUFF, SYDNEY 1643 §103 Final Rejection 12d Pending Nov 10, 2020
16860004 MULTIVASCULAR NETWORKS AND FUNCTIONAL INTRAVASCULAR TOPOLOGIES WITHIN BIOCOMPATIBLE HYDROGELS PELLEGRINO, BRIAN E 3799 §103§112 Final Rejection — Pending Apr 27, 2020
15550951 MATERIALS AND METHODS FOR TREATMENT OF HEMOGLOBINOPATHIES CANDELARIA, JULIANA IRENE 1600 §103DP Final Rejection — Pending Aug 14, 2017

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