Prosecution Insights
Last updated: October 02, 2026

Examiner: SPENCER, ANDREA LYNNE MORRIS

Tech Center 1600 • Art Units: 1631 1647

This examiner grants 22% of resolved cases

Analysis

Andrea Lynne Morris Spencer has a small record of 9 resolved cases in Tech Center 1600 and Art Unit 1631. The allowance rate of 22.2% is low, indicating a challenging environment for applicants. This is paired with a median days to allowance of 1402, which is a very long pendency period. The 9 resolved cases suggest a rigorous examination process that requires significant time.

The interview lift of 35.7% is a critical figure for practitioners. Despite the low 22.2% base allowance rate, the 35.7% lift suggests that interviews are quite effective at moving cases toward a grant. For the 9 resolved cases, the data indicates that verbal interaction is a key strategy for overcoming rejections. Practitioners should prepare for the 1402 days of pendency but use the 35.7% lift to improve their odds. In Art Unit 1631, the 22.2% allowance rate makes direct engagement a necessary part of the prosecution strategy. Verbal advocacy appears to be more effective than written arguments alone in this docket.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Performance Statistics

22.2%
Allow Rate
-37.8% vs TC avg
63
Total Applications
+35.7%
Interview Lift
1402
Avg Prosecution Days
Based on 9 resolved cases, 2023–2026

Rejection Statute Breakdown

3.5%
§101 Eligibility
17.6%
§102 Novelty
45.1%
§103 Obviousness
22.7%
§112 Clarity

Currently Pending Office Actions

App #TitleStatusAssignee
18339665 Compositions and Methods for Reducing HLA-A in a Cell Non-Final OA Intellia Therapeutics, Inc.
18031470 POLOXAMERS FOR CELL CULTURE Final Rejection MERCK PATENT GMBH
17407606 NONVIRAL GENERATION OF GENOME EDITED CHIMERIC ANTIGEN RECEPTOR T CELLS Final Rejection Wisconsin Alumni Research Foundation
17628913 Targeted RNA cleavage with CRISPR-Cas Final Rejection University of Rochester
17778079 Methods and Compositions for Generating Functionally Mature Beta Cells and Uses Thereof Final Rejection Washington University
17912889 COMPOSITIONS AND METHODS FOR ENHANCED LENTIVIRAL PRODUCTION Final Rejection Massachusetts Institute of Technology
17700880 GENETICALLY-EDITED IMMUNE CELLS AND METHODS OF THERAPY Final Rejection REGENTS OF THE UNIVERSITY OF MINNESOTA
17936286 VIRAL DELIVERY OF GAS VESICLE GENES Final Rejection California Institute of Technology
17426993 ADENO-ASSOCIATED VIRUS DELIVERY OF CLN6 POLYNUCLEOTIDE Final Rejection RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL
18194691 ANKYRIN-RICH BTB/POZ DOMAIN-CONTAINING PROTEIN-2 (ABTB2) FOR SUPPRESSING PANCREATIC CANCER GROWTH Final Rejection The Curators of the University of Missouri
18040648 NOVEL AAV CAPSIDS AND COMPOSITIONS CONTAINING SAME Non-Final OA The Trustees of the University of Pennsylvania
17997110 COMPOSITIONS AND METHODS FOR REDUCING NUCLEASE EXPRESSION AND OFF-TARGET ACTIVITY USING A PROMOTER WITH LOW TRANSCRIPTIONAL ACTIVITY Non-Final OA The Trustees of the University of Pennsylvania
17278679 EDITING OF HAEMOGLOBIN GENES Final Rejection Oxford University Innovation Limited
18269622 COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING GLYCOGEN STORAGE DISEASES Non-Final OA DUKE UNIVERSITY
17757475 Systems and Methods for Producing Efficacious Regulatory T Cells Non-Final OA H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE INC.
17917188 GENOME ENGINEERING METHOD AND GENOME ENGINEERING KIT Final Rejection Tokyo Institute of Technology
17627210 TRIPARTITE SYSTEMS FOR PROTEIN DIMERIZATION AND METHODS OF USE Non-Final OA MEDIMMUNE LIMITED
18331042 GENERATION OF CONDITIONED MEDIA FROM INDUCIBLE PLURIPOTENT STEM CELL DERIVED MESENCHYMAL STEM CELLS Non-Final OA CREATIVE MEDICAL TECHNOLOGIES, INC.
17995128 ENHANCEMENT OF THE PRODUCTION OF ADENOVIRUS-BASED GENE TRANSFER VECTORS Final Rejection Greffex, Inc.
17758077 CULTURE SYSTEMS FOR THE EFFICIENT PRODUCTION OF GENE TRANSFER VECTORS Final Rejection Greffex, Inc.
17778175 THERAPEUTIC ADENO-ASSOCIATED VIRUS COMPRISING LIVER-SPECIFIC PROMOTERS FOR TREATING POMPE DISEASE AND LYSOSOMAL DISORDERS Final Rejection ASKLEPIOS BIOPHARMACEUTICAL, INC.

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