Technology area: Biotechnology & Pharmaceuticals
92 pending office actions • 36 clients • 82 examiners • 47 art units • 0 of 92 (0%) have an AI response strategy ready
HOWSON & HOWSON LLP has 96 pending office actions in Biotechnology & Pharmaceuticals and 4036 career applications. Its resolved allowance rate is 78.17%, and the average is 3.6 office actions per allowance.
The profile shows a broad historical application base and a substantial current docket in biotechnology and pharmaceuticals. The resolved allowance rate provides an outcome measure, while the office-action average indicates the examination activity associated with allowances. For practitioners, the combination supports planning around both current workload and the response effort reflected in completed matters.
Based on the USPTO statutory response window for each pending office action. 21 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 21 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 + other | 14 (15%) |
| §103 only | 11 (12%) |
| §102 only | 2 (2%) |
| §112 only | 10 (11%) |
| Double-patenting only | 2 (2%) |
| Double-patenting + other | 14 (15%) |
| Multi-statute (no §101) | 39 (42%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| VIVLEMORE, TRACY ANN | 3 | 73.0% | +6.4% |
| UNDERDAHL, THANE E | 2 | 58.8% | +50.2% |
| BARRON, SEAN C | 2 | 52.7% | +30.4% |
| SZNAIDMAN, MARCOS L | 2 | 37.4% | +16.1% |
| SULLIVAN, STEPHANIE LAUREN | 2 | 57.1% | +38.1% |
| KONOPKA, CATHERINE ANNE | 2 | 57.5% | +66.2% |
| MYERS, CARLA J | 2 | 49.5% | +46.0% |
| SPENCER, ANDREA LYNNE MORRIS | 2 | 20.0% | +37.5% |
| SILVA RAINBOW, HEATHER ELISE | 2 | 31.4% | +56.3% |
| REID, MICHAEL ROBERT | 1 | 79.0% | +19.2% |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17995539 | REAWAKENING OF DORMANT TUMOR CELLS BY MODIFIED LIPIDS DERIVED FROM STRESS ACTIVATED NEUTROPHILS | KONOPKA, CATHERINE ANNE | 182d overdue |
| 17601542 | The Treatment of Protein Aggregation Diseases | JOHNSON, ALLISON MARIE | 125d overdue |
| 18863982 | Hybrid Solar Panel and Photovoltaic and Thermal Roof | CANNON, RYAN SMITH | 120d overdue |
| 18004404 | METHOD OF PRODUCING A FERTILISER COMPOSITION | SILVA RAINBOW, HEATHER ELISE | 50d overdue |
| 18257504 | CHEMICALLY MODIFIED CRISPR-CAS13 GUIDE RNAS | KONOPKA, CATHERINE ANNE | 38d overdue |
| 17356146 | IN VIVO DETECTION OF EGFR MUTATION IN GLIOBLASTOMA VIA MRI SIGNATURE CONSISTENT WITH DEEP PERITUMORAL INFILTRATION | SCHULTZHAUS, JANNA NICOLE | 36d overdue |
| 17999987 | COMPOSITIONS AND METHODS FOR NEGATIVE SELECTION OF NAIVE T AND B CELLS WITH A SINGLE ANTIBODY | CANDELARIA, JULIANA IRENE | 5d overdue |
| 18560153 | COMPOSITIONS AND METHODS FOR DEBULKING VIRUS OR MICROORGANISM LOAD IN THE ORAL CAVITY | MOAZZAMI, NAGHMEH NINA | 4d overdue |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17995539 | REAWAKENING OF DORMANT TUMOR CELLS BY MODIFIED LIPIDS DERIVED FROM STRESS ACTIVATED NEUTROPHILS | KONOPKA, CATHERINE ANNE | 182d overdue |
| 18004404 | METHOD OF PRODUCING A FERTILISER COMPOSITION | SILVA RAINBOW, HEATHER ELISE | 50d overdue |
| 18257504 | CHEMICALLY MODIFIED CRISPR-CAS13 GUIDE RNAS | KONOPKA, CATHERINE ANNE | 38d overdue |
| 17997110 | COMPOSITIONS AND METHODS FOR REDUCING NUCLEASE EXPRESSION AND OFF-TARGET ACTIVITY USING A PROMOTER WITH LOW TRANSCRIPTIONAL ACTIVITY | SPENCER, ANDREA LYNNE MORRIS | 6d |
| 19133922 | VALVE | REID, MICHAEL ROBERT | — |
| 18874238 | COMBINED USE OF A PROBIOTIC AND BUTYRIC ACID TO INCREASE THE ENTEROCYTE'S HEALTH AND CONSEQUENTLY THE WELLNESS OF PETS AND LIVESTOCK | UNDERDAHL, THANE E | — |
| 18865311 | PROBIOTIC FOR USE IN THE TREATMENT OF INFLAMMATORY ALTERATIONS OF THE INTESTINAL MUCOSA, PARTICULARLY OBESITY | UNDERDAHL, THANE E | — |
| 18712323 | COMPOSITIONS AND METHODS FOR TREATMENT OF FABRY DISEASE | BARRON, SEAN C | — |
| Art Unit | Apps |
|---|---|
| 1631 | 8 |
| 1638 | 6 |
| 1635 | 6 |
| 1637 | 4 |
| 1682 | 4 |
| 1699 | 3 |
| 1621 | 3 |
| 1634 | 3 |
| 1672 | 3 |
| 1636 | 3 |
| App # | Title | Client | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|---|
| 19133922 | VALVE | Fujikiin Incorporated | REID, MICHAEL ROBERT | 3753 | §102§103 | Non-Final OA | — | Pending | May 29, 2025 |
| 19109484 | ADJUSTABLE HEADREST | Mfi Italy Engineering S.r.l. | ABRAHAM, TANIA | 3636 | §102 | Non-Final OA | — | Pending | Mar 06, 2025 |
| 18575738 | SOLUTION FOR DESTROYING BIOFILMS AND METHOD OF PRODUCING THEREOF | Misera Co., Ltd. | HELM, CARALYNNE E | 1615 | §102§112 | Non-Final OA | — | Pending | Jan 24, 2025 |
| 18994948 | RECOMBINANT AAV HAVING AAV CLADE D AND CLADE E CAPSIDS AND COMPOSITIONS CONTAINING SAME | The Trustees of the University of Pennsylvania | LEONARD, ARTHUR S | 1631 | §101§103§112 | Non-Final OA | — | Pending | Jan 15, 2025 |
| 18992645 | COMPOSITIONS AND USES THEREOF | Optibiotix Limited | PAK, JOHN D | 1699 | §102§103§112 | Non-Final OA | — | Pending | Jan 09, 2025 |
| 18874238 | COMBINED USE OF A PROBIOTIC AND BUTYRIC ACID TO INCREASE THE ENTEROCYTE'S HEALTH AND CONSEQUENTLY THE WELLNESS OF PETS AND LIVESTOCK | Cerbios-Pharma SA | UNDERDAHL, THANE E | 1699 | §102§103DP | Non-Final OA | — | Pending | Dec 12, 2024 |
| 18869792 | ENERGY OPTIMIZATION OF A HEAT TRANSPORT SYSTEM | Grundfos Holding A/S | LIN, JASON | 2117 | §101§103§112 | Non-Final OA | — | Pending | Nov 26, 2024 |
| 18865311 | PROBIOTIC FOR USE IN THE TREATMENT OF INFLAMMATORY ALTERATIONS OF THE INTESTINAL MUCOSA, PARTICULARLY OBESITY | Cerbios-Pharma SA | UNDERDAHL, THANE E | 1699 | §102§103§112DP | Non-Final OA | — | Pending | Nov 12, 2024 |
| 18863982 | Hybrid Solar Panel and Photovoltaic and Thermal Roof | Sic Divisione Elettronica S.R.L.U. | CANNON, RYAN SMITH | 1726 | §102§103§112 | Non-Final OA | 120d overdue | Pending | Nov 07, 2024 |
| 18925333 | PIPELINE INSPECTION SYSTEM | Catholic Kwandong University Industry Foundation | SINGER, DAVID L | 2855 | §102§103 | Non-Final OA | — | Pending | Oct 24, 2024 |
| 18854774 | JOINT LEAKAGE DETECTION SYSTEM | Integrity Engineering Solutions Pty Ltd. | PLUMB, NIGEL H | 2855 | §102§103§112 | Non-Final OA | — | Pending | Oct 07, 2024 |
| 18853162 | BIODEGRADABLE LIPIDOIDS AND COMPOSITIONS AND METHODS OF USE THEREOF FOR LIVER TARGETED DELIVERY | The Trustees of the University of Pennsylvania | TCHERKASSKAYA, OLGA V | 1615 | §103§112DP | Non-Final OA | — | Pending | Oct 01, 2024 |
| 18890892 | GEOMETRICALLY TUNABLE HYDROGEL-BASED CHEMICALLY-ELUTING SHUNT PROSTHESIS | Drexel University | PELLEGRINO, BRIAN E | §103§112 | Non-Final OA | — | Pending | Sep 20, 2024 | |
| 18820706 | FASORACETAM CRYSTALLINE FORMS | The Children's Hospital of Philadelphia | AULAKH, CHARANJIT | 1621 | §102§103§112DP | Non-Final OA | — | Pending | Aug 30, 2024 |
| 18809628 | TUNGSTEN SINTERED SPUTTERING TARGET | JX Advanced Metals Corporation | LUK, VANESSA TIBAY | 1733 | §103§112 | Non-Final OA | — | Pending | Aug 20, 2024 |
| 18799659 | MODULATORS OF MYOCYTE LIPID ACCUMULATION AND INSULIN RESISTANCE AND METHODS OF USE THEREOF | The Trustees of the University of Pennsylvania | VAJDA, KRISTIN ANN | 1622 | §102§112DP | Non-Final OA | — | Pending | Aug 09, 2024 |
| 18833257 | PHAGE MEDIATED IMMUNO-PCR FOR THE DIAGNOSIS OF ALZHEIMER'S DISEASE | Universita’ Degli Studi Di Messina | KAPUSHOC, STEPHEN THOMAS | 1683 | §101§102§112 | Non-Final OA | — | Pending | Jul 25, 2024 |
| 18779936 | METHOD AND DEVICE FOR WASHING/CLEANING GRANULAR MATERIAL FROM SLAG AND WASHING/CLEANING BOTTOM/BOILER ASH FROM A THERMAL WASTE TREATMENT, AND MINERAL RESIDUE AND RECYCLING MATERIAL | H-U-R Hamburg GmbH Hamburger-Umwelt-Recyclingtechnologien | AYALEW, TINSAE B | 1711 | §103 | Final Rejection | 23d | Pending | Jul 22, 2024 |
| 18770804 | SAFETY QUICK-REFILL COMPACT PUMP FOR ADMINISTERING DRUGS | Cane' S.p.A. | BOUCHELLE, LAURA A | 3783 | §103§112Other | Non-Final OA | — | Pending | Jul 12, 2024 |
| 18727953 | COMPOSITIONS USEFUL IN TREATMENT OF METACHROMATIC LEUKODYSTROPHY | The Trustees of the University of Pennsylvania | WILSON, MICHAEL C | 1638 | §102§112Other | Non-Final OA | — | Pending | Jul 10, 2024 |
| 18737396 | SEQUENTIAL APPLICATION OF MACROPHAGES FOR WOUND HEALING | Drexel University | NICOL, ALEXANDER W | 1634 | §103 | Non-Final OA | — | Pending | Jun 07, 2024 |
| 18717294 | COMPOSITIONS AND METHODS FOR PREVENTION OR REDUCTION OF CARPA | The Trustees of the University of Pennsylvania | VOLKOV, ALEXANDER ALEXANDROVIC | 1612 | §102§103§112 | Non-Final OA | — | Pending | Jun 06, 2024 |
| 18713342 | FLAVANOID CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF FOR THE TREATMENT OF MITOCHONDRIAL DISORDERS | The Children's Hospital of Philadelphia | OLSON, ANDREA STEFFEL | 1693 | §101§102§103§112DP | Non-Final OA | — | Pending | May 24, 2024 |
| 18712323 | COMPOSITIONS AND METHODS FOR TREATMENT OF FABRY DISEASE | The Trustees of the University of Pennsylvania | BARRON, SEAN C | 1653 | §103 | Non-Final OA | — | Pending | May 22, 2024 |
| 18709415 | GENE THERAPY FOR TREATMENT OF MUCOPOLYSACCHARIDOSIS IIIA | The Trustees of the University of Pennsylvania | ALLEN, SARAH ELIZABETH | 1637 | §102§103§112Other | Non-Final OA | — | Pending | May 10, 2024 |
| 18702258 | COMPOSITIONS USEFUL IN TREATMENT OF CDKL5 DEFICIENCY DISORDER (CDD) | The Trustees of the University of Pennsylvania | SINGH, ANOOP KUMAR | 1632 | §112DP | Non-Final OA | — | Pending | Apr 17, 2024 |
| 18700437 | METHODS FOR INCREASING FAT ABSORPTION | Structured Lipid Nutrition, LLC | SZNAIDMAN, MARCOS L | 1628 | §102§103 | Non-Final OA | — | Pending | Apr 11, 2024 |
| 18698524 | COMPOSITIONS AND METHODS OF AMELIORATING AVERSIVENESS OF AVERSIVE STIMULI BY INHIBITION OF PURINERGIC RECEPTORS | Paul Breslin | CHICKS, ASHLI ARIANA | 1626 | §103§112 | Non-Final OA | — | Pending | Apr 04, 2024 |
| 18687571 | METHODS FOR EVALUATING TREATMENTS FOR BESTROPHINOPATHIES | The Trustees of the University of Pennsylvania | BARRON, SEAN C | 1653 | §101§103 | Non-Final OA | — | Pending | Feb 28, 2024 |
| 18579426 | METHOD FOR THE EXTRACTION OF POLICOSANOLS FROM INDUSTRIAL HEMP AND MIXTURE THEREOF | Sapienza Universita Di Roma | PAGANO, ALEXANDER R | 1692 | §101§102 | Non-Final OA | — | Pending | Jan 15, 2024 |
| 18578997 | MODIFIED ADAPTERS FOR ENZYMATIC DNA DEAMINATION AND METHODS OF USE THEREOF FOR EPIGENETIC SEQUENCING OF FREE AND IMMOBILIZED DNA | The Trustees of the University of Pennsylvania | CASH, KAILEY ELIZABETH | 1682 | §103§112DP | Non-Final OA | — | Pending | Jan 12, 2024 |
| 18570181 | AUTOMATED SYSTEM FOR CARRYING OUT CAPPING TESTS | Arol S.p.A. | PARCO JR, RUBEN C | 2853 | §112 | Final Rejection | 56d | Pending | Dec 14, 2023 |
| 18534114 | COMBINATION THERAPIES TARGETING MITOCHONDRIAL BIOGENESIS FOR CANCER THERAPY | The Wistar Institute | SZNAIDMAN, MARCOS L | 1628 | §102§112 | Non-Final OA | — | Pending | Dec 08, 2023 |
| 18567168 | VESSEL PROVIDED WITH AN IMPROVED AIR CIRCULATION SYSTEM | 3J Marine S.r.l. | BURGESS, MARC R | 3615 | §102§103§112 | Non-Final OA | 22d | Pending | Dec 05, 2023 |
| 18519972 | METHODS AND COMPOSITIONS FOR TREATING METASTATIC BREAST CANCER AND OTHER CANCERS IN THE BRAIN | The Trustees of the University of Pennsylvania | ARON, KIMBERLY A | 1633 | DP | Non-Final OA | — | Pending | Nov 27, 2023 |
| 18562293 | SPUTTERING TARGET AND METHOD FOR MANUFACTURING SAME | JX Metals Corporation | OTT, PATRICK S | 1794 | §103 | Final Rejection | — | Pending | Nov 18, 2023 |
| 18560153 | COMPOSITIONS AND METHODS FOR DEBULKING VIRUS OR MICROORGANISM LOAD IN THE ORAL CAVITY | The Trustees of the University of Pennsylvania | MOAZZAMI, NAGHMEH NINA | 1652 | §103§112Other | Final Rejection | 4d overdue | Pending | Nov 10, 2023 |
| 18504261 | GENE THERAPY FOR OCULAR DISORDERS | The Trustees of the University of Pennsylvania | ZHU, JIANJIAN | 1631 | §103 | Non-Final OA | — | Pending | Nov 08, 2023 |
| 18497386 | METHODS OF DIAGNOSING AND TREATING CONDUCT DISORDER | The Children's Hospital of Philadelphia | KOSAR, ANDREW D | 1625 | §103§112 | Non-Final OA | — | Pending | Oct 30, 2023 |
| 18557834 | COMPOSITIONS AND METHODS OF TREATING SEPSIS IN PATIENTS USING ANTI-LIGHT ANTIBODIES | The Trustees of the University of Pennsylvania | SCHWECHTER, BRANDON ROSS | 1798 | §102§112 | Non-Final OA | — | Pending | Oct 27, 2023 |
| 18556944 | COMPOSITIONS AND METHODS FOR IN VIVO NUCLEASE-MEDIATED GENE TARGETING FOR THE TREATMENT OF GENETIC DISORDERS | The Trustees of the University of Pennsylvania | SULLIVAN, STEPHANIE LAUREN | 1635 | §103§112DP | Non-Final OA | — | Pending | Oct 24, 2023 |
| 18556668 | COMPOSITIONS AND METHODS FOR PREVENTING RSV AND PIV3 INFECTIONS | UNIVERSITY OF SASKATCHEWAN | CHEN, STACY BROWN | 1672 | §112 | Non-Final OA | — | Pending | Oct 21, 2023 |
| 18287150 | COMPOSITIONS AND METHODS USEFUL FOR THE TREATMENT OF H-ABC LEUKODYSTROPHY | The Children's Hospital of Philadelphia | HUDSON, AMY ROSE | 1636 | §102§103§112 | Non-Final OA | — | Pending | Oct 16, 2023 |
| 18555189 | ANTI-FIBROBLAST ACTIVATION PROTEIN ANTIBODIES | Philogen S.P.A | BERHANE, SELAM | 1675 | §112 | Non-Final OA | — | Pending | Oct 12, 2023 |
| 18554748 | COMPOSITIONS USEFUL FOR TREATING SPINAL AND BULBAR MUSCULAR ATROPHY (SBMA) | The Trustees of the University of Pennsylvania | SCHULTZ, JAMES | 1631 | §103§112Other | Non-Final OA | — | Pending | Oct 10, 2023 |
| 18550070 | COMPOSITIONS AND METHODS USEFUL FOR THE TREATMENT OF BONE MARROW FAILURE DISEASES ASSOCIATED WITH RIBOSOMOPATHIES | The Children's Hospital of Philadelphia | PERSONS, JENNA L | 1637 | §101§102§103§112 | Non-Final OA | — | Pending | Sep 11, 2023 |
| 18546321 | Composition and Use Thereof | Axisbiotix Limited | DEVI, SARVAMANGALA | 1645 | §112 | Final Rejection | — | Pending | Aug 14, 2023 |
| 18264885 | COMPOSITIONS AND METHODS FOR TREATING PULMONARY ARTERIAL HYPERTENSION (PAH) AND OTHER DISORDERS | The Trustees of the University of Pennsylvania | LIPPOLIS, ALEXANDRA ROSE | 1637 | §102§103§112 | Non-Final OA | — | Pending | Aug 09, 2023 |
| 17906173 | TARGETED DELIVERY OF EXTRACELLULAR VESICLES | Evox Therapeutics Ltd. | HAMA, JOANNE | 1647 | §103§112 | Final Rejection | 71d | Pending | Jul 27, 2023 |
| 18263085 | COMPOSITIONS AND METHODS FOR TREATMENT OF NIEMANN PICK TYPE A DISEASE | The Trustees of the University of Pennsylvania | TATGE, LEXUS MARC | 1637 | §102§103§112 | Non-Final OA | — | Pending | Jul 26, 2023 |
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Start Free Trial78.2% of resolved applications prosecuted by Howson & Howson LLP were allowed, across 4,036 applications in USPTO records.
3.60 office actions per allowed application on average.
92 pending office actions as of October 2026, for 36 clients, before 82 examiners in 47 art units.
