Technology area: Biotechnology & Pharmaceuticals
86 pending office actions • 54 art units • 81 examiners • 0 of 86 (0%) have an AI response strategy ready • 75 patents granted in the last 365 days
Columbia University currently manages 1 pending office action within the Medical Devices & Mechanical Engineering technology area. This action is assigned to a distinct examiner and a distinct art unit. The limited number of active matters suggests a focused approach for this specific filing. Practitioners can observe that the prosecution landscape is concentrated, with limited distribution across different technical groups.
The busiest examiner, PRONE, CHRISTOPHER D, is handling 1 busiest examiner pending action. As the only examiner currently assigned to the university's matters, PRONE, CHRISTOPHER D represents the entirety of the active prosecution landscape. The distinct art unit confirms that the technology is being evaluated within a single specialized group. Practitioners should tailor their strategy to the specific tendencies of the examiner to address the pending office action.
The involvement of PRONE, CHRISTOPHER D as the busiest examiner means that feedback and requirements originate from this specific source. This structure simplifies the coordination needed to address the 1 busiest examiner pending action. Practitioners can focus their strategy on the specific examination style of the examiner to advance the 1 pending office action toward allowance in the Medical Devices & Mechanical Engineering technology area.
Based on the USPTO statutory response window for each pending office action. 30 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 30 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 + other | 6 (7%) |
| §103 only | 16 (19%) |
| §102 only | 2 (2%) |
| §112 only | 8 (9%) |
| Double-patenting only | 1 (1%) |
| Double-patenting + other | 11 (13%) |
| Multi-statute (no §101) | 42 (49%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| NELSON, MICHAEL B | 2 | 21.5% | +37.3% |
| ALABI, OYELEYE A | 2 | 83.9% | +23.8% |
| DONOHUE, SEAN R | 2 | 41.4% | +21.0% |
| HERNANDEZ, JACKSON J | 2 | 50.7% | +39.2% |
| ALLEN, MICHAEL D | 2 | 31.9% | +48.8% |
| DUBOSE, LAUREN | 1 | 59.1% | +46.2% |
| REGLAS, GEORGIANA C | 1 | 39.2% | +33.4% |
| HOLMES, REX R | 1 | 80.1% | +17.9% |
| KWON, JOHN SEUNGJAI | 1 | 44.9% | +20.2% |
| VIJAYARAGHAVAN, JAGAMYA NMN | 1 | 61.0% | +51.0% |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17436023 | COMPOSITIONS OF MATTER WITH ACTIVITY TO REMOVE LIPOFUSCIN FROM RETINAL CELLS | BAKSHI, PANCHAM | 181d overdue |
| 17920475 | AN AUTOMATED CONTROLLED RELEASE DEVICE FOR LIVESTOCK MANAGEMENT AND METHODS OF USE THEREOF | KOHUTKA, BROOKE NICOLE | 87d overdue |
| 17064352 | INORGANIC NANOCAGES, AND METHODS OF MAKING AND USING SAME | ROGERS, JAMES WILLIAM | 70d overdue |
| 17973683 | MECHANICAL VACUUM DRESSING FOR MECHANICALLY MANAGING, PROTECTING AND SUCTIONING SMALL INCISIONAL WOUNDS | TRAN, NHU | 44d overdue |
| 17920931 | METHODS FOR DETECTING TISSUE DAMAGE, GRAFT VERSUS HOST DISEASE, AND INFECTIONS USING CELL-FREE DNA PROFILING | BAUSCH, SARAE L | 38d overdue |
| 18029596 | METHODS AND COMPOSITIONS FOR INCREASING UPTAKE, INTERNALIZATION, AND/OR RETENTION OF SMALL MOLECULE LIGANDS | DONOHUE, SEAN R | 36d overdue |
| 18006476 | CHELATION CROSSLINKED POLYMERS, METHODS OF MAKING SAME, AND USES THEREOF | NGUYEN, HA S | 35d overdue |
| 17969392 | FLUORINE-FREE OIL REPELLENT COATING, METHODS OF MAKING SAME, AND USES OF SAME | NELSON, MICHAEL B | 26d overdue |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18029596 | METHODS AND COMPOSITIONS FOR INCREASING UPTAKE, INTERNALIZATION, AND/OR RETENTION OF SMALL MOLECULE LIGANDS | DONOHUE, SEAN R | 36d overdue |
| 17969392 | FLUORINE-FREE OIL REPELLENT COATING, METHODS OF MAKING SAME, AND USES OF SAME | NELSON, MICHAEL B | 26d overdue |
| 18247427 | METHODS AND COMPOSITIONS FOR SYNERGISTIC UPTAKE AND RETENTION OF SMALL MOLECULE LIGANDS | DONOHUE, SEAN R | 11d overdue |
| 18020025 | THERAPEUTICALLY USEFUL CURE-PRO MOLECULES FOR E3 LIGASE MEDIATED DEGRADATION OF PROTEINS, AND METHODS OF MAKING AND USING THEM | HERNANDEZ, JACKSON J | 14d |
| 18020019 | THERAPEUTIC COMPOSITION OF CURE-PRO COMPOUNDS FOR TARGETED DEGRADATION OF BET DOMAIN PROTEINS, AND METHODS OF MAKING AND USAGE | HERNANDEZ, JACKSON J | 14d |
| 19239415 | MITRAL VALVES WITH INTEGRATED CUTTING FEATURES | DUBOSE, LAUREN | — |
| 19054625 | THERARONSTIC APPROACH FOR INFLAMMATORY BOWEL DISEASE-ASSOCIATED SPONDYLOARTHRITIS | REGLAS, GEORGIANA C | — |
| 18877209 | INTRAVAGINAL DEVICE FOR TREATING PELVIC PAIN | HOLMES, REX R | — |
| Art Unit | Apps |
|---|---|
| 1618 | 8 |
| 1633 | 4 |
| 3774 | 3 |
| 1699 | 3 |
| 1638 | 3 |
| 1627 | 3 |
| 3771 | 2 |
| 1651 | 2 |
| 1615 | 2 |
| 1629 | 2 |
| App # | Title | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|
| 19239415 | MITRAL VALVES WITH INTEGRATED CUTTING FEATURES | DUBOSE, LAUREN | 3771 | §102§103DP | Non-Final OA | — | Pending | Jun 16, 2025 |
| 19054625 | THERARONSTIC APPROACH FOR INFLAMMATORY BOWEL DISEASE-ASSOCIATED SPONDYLOARTHRITIS | REGLAS, GEORGIANA C | 1651 | §101§103§112 | Non-Final OA | — | Pending | Feb 14, 2025 |
| 18877209 | INTRAVAGINAL DEVICE FOR TREATING PELVIC PAIN | HOLMES, REX R | 3796 | §102§103 | Non-Final OA | — | Pending | Dec 19, 2024 |
| 18865710 | PROTEIN PARTICLES INCLUDING AN ACTIVE AGENT AND METHODS OF MAKING AND USING THE SAME | KWON, JOHN SEUNGJAI | 1615 | §102§103§112DP | Non-Final OA | — | Pending | Nov 14, 2024 |
| 18863977 | ADAPTATIONS FOR HIGH EFFICIENCY AND ALTERED PAM USAGE WITH TN7-CRISPR-CAS TRANSPOSITION SYSTEMS | VIJAYARAGHAVAN, JAGAMYA NMN | 1633 | §112 | Non-Final OA | — | Pending | Nov 07, 2024 |
| 18861012 | ACTIVE AND/OR INTELLIGENT PACKAGING MATERIALS CONTAINING RADICAL SCAVENGING LIGANDS | WOLLSCHLAGER, JEFFREY MICHAEL | 1742 | §102§103 | Non-Final OA | — | Pending | Oct 28, 2024 |
| 18922685 | METHOD AND APPARATUS FOR PROVIDING INCREASED VISUALIZATION AND MANIPULATION OF A BODY SIDE WALL | GABR, MOHAMED GAMIL | 3771 | §102§103 | Non-Final OA | — | Pending | Oct 22, 2024 |
| 18919922 | ENHANCED DISEASE RESISTANCE IN PLANTS | BUI, PHUONG T | 1663 | §102§112 | Non-Final OA | — | Pending | Oct 18, 2024 |
| 18911705 | NANOPARTICLE DRUG CONJUGATES | DICKINSON, PAUL W | 1618 | §102§103§112DP | Non-Final OA | — | Pending | Oct 10, 2024 |
| 18908740 | ULTRASMALL NANOPARTICLES AND METHODS OF MAKING AND USING SAME | CABRAL, ROBERT S | 1614 | §102§103 | Non-Final OA | — | Pending | Oct 07, 2024 |
| 18824827 | EXTRUSION OF AGRO-FOOD INDUSTRY BYPRODUCTS AND PROTEIN CONCENTRATES INTO VALUE-ADDED FOODS | WATTS, JENNA A | 1791 | §102§103DP | Non-Final OA | — | Pending | Sep 04, 2024 |
| 18841883 | ENGINEERED IMMUNOMODULATORY ACCESSORY CELLS IMPROVE ALLOGENEIC ISLET TRANSPLANTATION WITHOUT IMMUNOSUPPRESSION | LARA, CAROLINE MONSERRAT | 1633 | §102§103§112 | Non-Final OA | — | Pending | Aug 27, 2024 |
| 18779607 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | SAMALA, JAGADISHWAR RAO | 1618 | DP | Non-Final OA | — | Pending | Jul 22, 2024 |
| 18767630 | SYSTEMS AND METHODS FOR MICROPATTERNING OBJECTS | PATEL, AREN | 3774 | §103 | Final Rejection | 10d overdue | Pending | Jul 09, 2024 |
| 18726342 | COMBINATION THERAPIES INCLUDING PARP1 INHIBITORS | SHOWALTER, ALEXANDER KEITH | 1629 | §103§112 | Non-Final OA | — | Pending | Jul 02, 2024 |
| 18757200 | IRE1 SMALL MOLECULE INHIBITORS | KIFLE, BRUCK | 1624 | §112DP | Non-Final OA | — | Pending | Jun 27, 2024 |
| 18725018 | COMPOSITIONS AND METHODS FOR SOLUBILIZING GLYCOSYLTRANSFERASES | UNDERDAHL, THANE E | 1699 | §112 | Non-Final OA | — | Pending | Jun 27, 2024 |
| 18722792 | METHODS FOR ENHANCED NUCLEIC ACID DELIVERY | FALKOWITZ, ANNA R | 1600 | §103§112DP | Final Rejection | 10d overdue | Pending | Jun 21, 2024 |
| 18739113 | UFMYLATION INHIBITION TO TARGET TAUOPATHY IN HUMAN NEURONS | MARTIN, PAUL C | 1653 | §102§103§112 | Non-Final OA | — | Pending | Jun 10, 2024 |
| 18716858 | METHODS AND COMPOSITIONS FOR GENETICALLY MODIFYING HUMAN GUT MICROBES | DHAR, MATASHA | 1632 | §102§103§112 | Non-Final OA | — | Pending | Jun 05, 2024 |
| 18711287 | RNA SEQUENCES THAT INDUCE FLUORESCENCE OF SMALL MOLECULE FLUOROPHORES, MOLECULAR COMPLEXES, SENSORS, AND METHODS OF USE THEREOF | MOORE, JOHN DAVID | 1638 | §102 | Non-Final OA | — | Pending | May 17, 2024 |
| 18696840 | NICOTINAMIDE RIBOSIDE TRIOLEATES CHLORIDE, COMPOSITIONS CONTAINING THIS COMPOUND, AND METHODS OF MAKING AND USING THIS COMPOUND | CRAIGO, BAHAR ALAWI | 1699 | §112 | Non-Final OA | — | Pending | Mar 28, 2024 |
| 18687608 | COMPOSITIONS AND METHODS FOR CELL REPROGRAMMING | BARRON, SEAN C | 1653 | §102§103 | Non-Final OA | — | Pending | Feb 28, 2024 |
| 18686564 | MULTIVALENT VIRAL PARTICLES | GRIZER, CASSANDRA SENN | 1672 | §102§103 | Non-Final OA | — | Pending | Feb 26, 2024 |
| 18433538 | METHODS OF CANCER TREATMENT VIA REGULATED FERROPTOSIS | WHEELER, THURMAN MICHAEL | 1619 | §102§103§112 | Non-Final OA | — | Pending | Feb 06, 2024 |
| 18681728 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | SHIAO, YIH-HORNG | 1691 | §102§103§112 | Non-Final OA | — | Pending | Feb 06, 2024 |
| 18293204 | POLYMER NANOPARTICLES VIA CONDENSED DROPLET POLYMERIZATION | STEVENS, MARK V | 1613 | §103§112 | Final Rejection | — | Pending | Jan 29, 2024 |
| 18420584 | IN-LINE ORAL DEVICE FOR SLEEP APNEA | MILLER, DANIEL A | 3786 | §102 | Non-Final OA | — | Pending | Jan 23, 2024 |
| 18562243 | APT1 and APT2 Inhibitors and Uses Thereof | CHENG, KAREN | 1623 | §102§112 | Non-Final OA | — | Pending | Nov 17, 2023 |
| 18561592 | CONTACTLESS ACOUSTOFLUIDIC SAMPLE AGITATOR AND USES THEREOF | SORKIN, DAVID L | 1799 | §102§103§112 | Non-Final OA | — | Pending | Nov 16, 2023 |
| 18560820 | EXTERNAL CRANIAL PROSTHESIS | SHARMA, YASHITA | 3774 | §102§103 | Non-Final OA | — | Pending | Nov 14, 2023 |
| 18559491 | METHOD FOR PROTECTING REACTIVE MATERIALS WITH ATOMICALLY THIN FILM | STEVENSON, ANDRE C | 2899 | §103§112 | Non-Final OA | 75d | Pending | Nov 07, 2023 |
| 18557888 | HYDROPHOBIC AND OLEOPHOBIC COATINGS, METHODS OF MAKING SAME AND USES OF SAME | NELSON, MICHAEL B | 1787 | §103 | Final Rejection | — | Pending | Oct 27, 2023 |
| 18555184 | IMPLANTABLE CELL ENCAPSULATION SYSTEMS | HARRIS, WESLEY G | 3783 | §102§103§112 | Non-Final OA | — | Pending | Oct 12, 2023 |
| 18286315 | OPTICAL CLEARING AND AUTO-FLUORESCENCE QUENCHING SOLUTIONS AND METHOD OF USE FOR ENHANCED MICROSCOPY IMAGING OF BIOLOGICAL TISSUES | XU, QING | 1656 | §102§103§112DP | Non-Final OA | — | Pending | Oct 10, 2023 |
| 18285920 | A MULTIPLEX ASSAY FOR THE DIAGNOSIS OF BRUCELLA CANIS INFECTION | CHHAY, BONIRATH | 1645 | §103§112 | Non-Final OA | — | Pending | Oct 06, 2023 |
| 18552566 | ULTRATHIN POLYMER FILMS AS PROTECTIVE COATINGS FOR BATTERY ELECTRODES | BERNATZ, KEVIN M | 1785 | §102§112 | Non-Final OA | — | Pending | Sep 26, 2023 |
| 18551786 | ORAL DELIVERY OF SILICA/ALUMINOSILICATE NANOPARTICLES | WESTERBERG, NISSA M | 1618 | §103DP | Non-Final OA | — | Pending | Sep 21, 2023 |
| 18281440 | METHODS FOR IMPROVING POULTRY HEALTH | SEITZ, ANTHONY JOSEPH | 1629 | §102§103§112 | Non-Final OA | — | Pending | Sep 11, 2023 |
| 18547725 | SYSTEMS AND METHODS FOR USING DEEP-LEARNING ALGORITHMS TO FACILITATE DECISION MAKING IN GYNECOLOGIC PRACTICE | TOKARCZYK, CHRISTOPHER B | 3687 | §103 | Non-Final OA | 28d | Pending | Aug 24, 2023 |
| 18277519 | Integrated Quantum Computing with Epitaxial Materials | PATERSON, BRIGITTE A | 2896 | §102§112 | Non-Final OA | — | Pending | Aug 16, 2023 |
| 18262509 | POLY(CYCLIC ACETAL)S, METHODS OF MAKING SAME, AND USES THEREOF | SERGENT, RABON A | 1765 | §103 | Non-Final OA | — | Pending | Jul 21, 2023 |
| 18262053 | ARTEMISININ-PROTEASOME INHIBITOR CONJUGATES AND THEIR USE IN THE TREATMENT OF DISEASE | NESTOR, DONNA MICHELLE | 1627 | §103 | Final Rejection | 16d | Pending | Jul 19, 2023 |
| 18259105 | MULTI-VOLUME MICROCHAMBER-BASED MICROFLUIDIC PLATFORM AND USE THEREOF | ALABI, OYELEYE A | 1797 | §102§103 | Non-Final OA | — | Pending | Jun 23, 2023 |
| 18259101 | GRADIENT-BASED MICROFLUIDIC CIRCUIT, DEVICE, AND METHOD FOR PERFORMING AN ASSAY | ALABI, OYELEYE A | 1797 | §102§103 | Non-Final OA | — | Pending | Jun 23, 2023 |
| 18268472 | ZWITTERIONIC LIPID NANOPARTICLE COMPOSITIONS, AND METHODS OF USE | LIPPERT, JOHN WILLIAM | 1615 | §103§112 | Non-Final OA | — | Pending | Jun 20, 2023 |
| 18249938 | SOLUTION ELECTROWRITING | SPENCER, MAXIMILIAN TOBIAS | 3774 | §102§103 | Non-Final OA | 26d | Pending | Apr 20, 2023 |
| 18247427 | METHODS AND COMPOSITIONS FOR SYNERGISTIC UPTAKE AND RETENTION OF SMALL MOLECULE LIGANDS | DONOHUE, SEAN R | 1618 | §103§112Other | Final Rejection | 11d overdue | Pending | Mar 30, 2023 |
| 18029596 | METHODS AND COMPOSITIONS FOR INCREASING UPTAKE, INTERNALIZATION, AND/OR RETENTION OF SMALL MOLECULE LIGANDS | DONOHUE, SEAN R | 1618 | §103§112Other | Final Rejection | 36d overdue | Pending | Mar 30, 2023 |
| 18128821 | METAL-ORGANIC FRAMEWORKS FOR THE STORAGE AND DELIVERY OF HYDROGEN SULFIDE, METHODS OF MAKING AND USES OF SAME | PHAN, ANNETTE HOANG-ANH | 1736 | §102§112 | Final Rejection | 4d overdue | Pending | Mar 30, 2023 |
IP Author helps IP teams respond to office actions faster with AI-generated responses, examiner analytics, and prosecution intelligence.
Start Free TrialColumbia University has 86 pending office actions as of October 2026, spread across 54 art units and 81 examiners.
Michael B Nelson has the most, with 2 of Columbia University's pending office actions.
Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.
