Prosecution Insights
Last updated: October 02, 2026

Salk Institute for Biological Studies

Technology area: Biotechnology & Pharmaceuticals

14 pending office actions • 8 art units • 13 examiners • 0 of 14 (0%) have an AI response strategy ready • 10 patents granted in the last 365 days

Analysis

The Salk Institute for Biological Studies currently manages 14 pending office actions within the Biotechnology & Pharmaceuticals technology area. These 14 actions are distributed across 8 distinct art units, reflecting a broad range of biological research. The prosecution involves 13 distinct examiners, which indicates that almost every pending case is being reviewed by a different individual.

BRETZ, COREY LANE is the busiest examiner for this portfolio, currently overseeing 2 pending office actions. This count of 2 is the highest number of actions assigned to any single examiner in the group. With 13 distinct examiners for 14 pending office actions, the workload is highly distributed, with only BRETZ, COREY LANE handling more than one case.

The 8 distinct art units involved mean that the 14 pending office actions are subject to the standards of many different examination groups. Practitioners should note that they will be dealing with 13 different examiners, which may lead to a variety of prosecution experiences. The 2 pending office actions under BRETZ, COREY LANE represent the only point of examiner overlap in the current Biotechnology & Pharmaceuticals portfolio.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

14
Total Pending OAs
7
Non-Final OAs
7
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 4 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

3
Overdue
0
Due this week
0
Due this month
1
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 4 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (3)Due ≤ 60 days (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

6
Hard (43%)
6
Medium (43%)
2
Easy (14%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other2 (14%)
§103 only1 (7%)
§102 only1 (7%)
§112 only1 (7%)
Double-patenting only1 (7%)
Double-patenting + other4 (29%)
Multi-statute (no §101)4 (29%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

13
Life Sciences
93% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
1
Business / Other
7% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

140 h
Manual time on pending OAs
28 h
Time saved (low, 20%)
49 h
Time saved (mid, 35%)
1.2 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
BRETZ, COREY LANE 2 0.0% +0.0%
MEYER, GEORGE WILLIAM 1 100.0% +0.0%
CHATTERJEE, JAYANTA 1 45.5% +80.0%
GILL, RACHEL B 1 65.6% +28.3%
SHIN, DANA H 1 27.0% +27.0%
LEONARD, ARTHUR S 1 50.8% +50.2%
VANHORN, ABIGAIL LOUISE 1 46.8% +22.4%
CHONG, YONG SOO 1 43.8% +41.6%
KIM, TAEYOON 1 51.5% +52.1%
PRONZATI, GINA 1 66.7% +45.9%

Hard Cases (9)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17769524 METHODS FOR MODULATING HUMAN L1 RETROTRANSPOSONS RNA AND COMPOSITIONS FOR USE THEREIN KIM, TAEYOON 147d overdue
17637058 COMPOSITIONS AND METHODS FOR IN VIVO GENE EDITING LIPPOLIS, ALEXANDRA ROSE 125d overdue
17104372 TARGETED GENE ACTIVATION USING MODIFIED GUIDE RNA RAVINDRA, KRISHNA NUGGEHALLI 34d
18954772 IRON MAN (IMA) OVEREXPRESSION INCREASES DISEASE RESISTANCE MEYER, GEORGE WILLIAM —
18840877 COMPOSITIONS AND METHODS FOR INCREASING PERIDERM IN PLANT ROOTS CHATTERJEE, JAYANTA —
18797069 HSV-1 ONCOLYTIC VIRUS THERAPIES THAT SPECIFICALLY KILL ALT DEPENDENT CANCERS GILL, RACHEL B —
18288772 MULTIPLEX CRISPR/Cas9-MEDIATED TARGET GENE ACTIVATION SYSTEM SHIN, DANA H —
18151093 RECOMBINANT ADENOVIRUS GENOME HAVING A SYNTHETIC TRANSCRIPTIONAL UNIT AND TWO STEP TRANSCRIPTIONAL REGULATION AND AMPLIFICATION BRETZ, COREY LANE —

Interview Candidates (8)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17769524 METHODS FOR MODULATING HUMAN L1 RETROTRANSPOSONS RNA AND COMPOSITIONS FOR USE THEREIN KIM, TAEYOON 147d overdue
18028751 PATIENT SELECTION BIOMARKERS FOR TREATMENT WITH ULK INHIBITORS VANHORN, ABIGAIL LOUISE 19d overdue
18840877 COMPOSITIONS AND METHODS FOR INCREASING PERIDERM IN PLANT ROOTS CHATTERJEE, JAYANTA —
18797069 HSV-1 ONCOLYTIC VIRUS THERAPIES THAT SPECIFICALLY KILL ALT DEPENDENT CANCERS GILL, RACHEL B —
18288772 MULTIPLEX CRISPR/Cas9-MEDIATED TARGET GENE ACTIVATION SYSTEM SHIN, DANA H —
18302962 SYNTHETIC ADENOVIRUSES TARGETING BONE TISSUE AND USES THEREOF LEONARD, ARTHUR S —
17990489 FLAVONE DERIVATIVES AND USES IN TARGETING CK2-MEDIATED DISEASES AND CONDITIONS CHONG, YONG SOO —
17681538 ADENOVIRAL ASSEMBLY METHOD PRONZATI, GINA —

Top Art Units

Art UnitApps
1635 3
1662 2
1631 2
1636 2
1623 1
1633 1
1637 1
1626 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18954772 IRON MAN (IMA) OVEREXPRESSION INCREASES DISEASE RESISTANCE MEYER, GEORGE WILLIAM 1662 §103§112 Non-Final OA — Pending Nov 21, 2024
18840877 COMPOSITIONS AND METHODS FOR INCREASING PERIDERM IN PLANT ROOTS CHATTERJEE, JAYANTA 1662 §102§103§112 Non-Final OA — Pending Aug 22, 2024
18797069 HSV-1 ONCOLYTIC VIRUS THERAPIES THAT SPECIFICALLY KILL ALT DEPENDENT CANCERS GILL, RACHEL B — §101§103§112DP Non-Final OA — Pending Aug 07, 2024
18288772 MULTIPLEX CRISPR/Cas9-MEDIATED TARGET GENE ACTIVATION SYSTEM SHIN, DANA H 1635 §103§112DPOther Non-Final OA — Pending Oct 27, 2023
18302962 SYNTHETIC ADENOVIRUSES TARGETING BONE TISSUE AND USES THEREOF LEONARD, ARTHUR S 1631 §112 Final Rejection — Pending Apr 19, 2023
18028751 PATIENT SELECTION BIOMARKERS FOR TREATMENT WITH ULK INHIBITORS VANHORN, ABIGAIL LOUISE 1636 §103DP Final Rejection 19d overdue Pending Apr 12, 2023
18151093 RECOMBINANT ADENOVIRUS GENOME HAVING A SYNTHETIC TRANSCRIPTIONAL UNIT AND TWO STEP TRANSCRIPTIONAL REGULATION AND AMPLIFICATION BRETZ, COREY LANE 1635 §102§103§112DP Non-Final OA — Pending Jan 06, 2023
17990489 FLAVONE DERIVATIVES AND USES IN TARGETING CK2-MEDIATED DISEASES AND CONDITIONS CHONG, YONG SOO 1623 §102Other Final Rejection — Pending Nov 18, 2022
17741311 COMPOSITIONS AND METHODS FOR HIGH-EFFICIENCY RECOMBINATION OF RNA MOLECULES BRETZ, COREY LANE 1635 §112DP Non-Final OA — Pending May 10, 2022
17769524 METHODS FOR MODULATING HUMAN L1 RETROTRANSPOSONS RNA AND COMPOSITIONS FOR USE THEREIN KIM, TAEYOON 1631 §102§103 Final Rejection 147d overdue Pending Apr 15, 2022
17681538 ADENOVIRAL ASSEMBLY METHOD PRONZATI, GINA 1633 DP Final Rejection — Pending Feb 25, 2022
17637058 COMPOSITIONS AND METHODS FOR IN VIVO GENE EDITING LIPPOLIS, ALEXANDRA ROSE 1637 §101§102§103 Final Rejection 125d overdue Pending Feb 21, 2022
17104372 TARGETED GENE ACTIVATION USING MODIFIED GUIDE RNA RAVINDRA, KRISHNA NUGGEHALLI 1636 §103§112 Final Rejection 34d Pending Nov 25, 2020
18403664 METHODS OF TREATING NEURODEGENERATIVE DISEASES OR CONDITIONS PATEL, SAGAR S 1626 §103 Non-Final OA — Pending Jan 03, 2024

Managing Salk Institute for Biological Studies's Patent Portfolio?

IP Author helps IP teams respond to office actions faster with AI-generated responses, examiner analytics, and prosecution intelligence.

Start Free Trial

Sign in with your work email

Enter your email to receive a magic link. No password needed.

Personal email addresses (Gmail, Yahoo, etc.) are not accepted.

Free tier: 3 strategy analyses per month