Prosecution Insights
Last updated: April 19, 2026

Examiner: RAVINDRA, KRISHNA NUGGEHALLI

Tech Center 1600 • Art Units: 1636

This examiner grants 80% of resolved cases

Performance Statistics

80.0%
Allow Rate
+20.0% vs TC avg
37
Total Applications
+33.3%
Interview Lift
1214
Avg Prosecution Days
Based on 10 resolved cases, 2023–2026

Rejection Statute Breakdown

8.6%
§101 Eligibility
20.8%
§102 Novelty
31.7%
§103 Obviousness
33.0%
§112 Clarity

Currently Pending Office Actions

App #TitleStatusAssignee
18042729 VIRAL VECTOR ENCODING GLP-1 RECEPTOR AGONIST FUSIONS AND USES THEREOF IN TREATING METABOLIC DISEASES IN FELINES Non-Final OA The Trustees of the University of Pennsylvania
18023259 GENE KNOCK-OUT FOR TREATMENT OF GLAUCOMA Final Rejection University of Iowa Research Foundation
17602540 PIP4Ks SUPPRESS INSULIN SIGNALING AND ENHANCE IMMUNE FUNCTION THROUGH A CATALYTIC-INDEPENDENT MECHANISM Non-Final OA Cornell University
18066890 GENETIC FACTOR TO INCREASE EXPRESSION OF RECOMBINANT PROTEINS Non-Final OA Impossible Foods Inc.
17104372 TARGETED GENE ACTIVATION USING MODIFIED GUIDE RNA Final Rejection Salk Institute for Biological Studies
18096538 miRNA, and Derivative Thereof and Use Thereof Non-Final OA South China Normal University
17633593 Antisense oligonucleotides rescue aberrant splicing of ABCA4 Non-Final OA UCL Business Ltd
18000640 PROGRAMMABLE NUCLEASES AND METHODS OF USE Non-Final OA Mammoth Biosciences, Inc.
18269582 Gene therapy DNA vector based on gene therapy DNA vector VTvaf17 carrying the therapeutic gene selected from the group of KRT5, KRT14, LAMB3, and COL7A1 genes for increasing the expression level of these therapeutic genes, method of its production and use, Escherichia coli strain SCS110-AF/VTvaf17-KRT5, or Escherichia coli strain SCS110-AF/VTvaf17-KRT14, or Escherichia coli strain SCS110-AF/VTvaf17-LAMB3, or Escherichia coli strain SCS110-AF/VTvaf17-COL7A1 carrying the gene therapy DNA vector, m Non-Final OA OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTJU "PRORYVNYE INNOVATSIONNYE TEKHNOLOGII"
17612547 TREATMENT OF ALT CANCERS Non-Final OA TESSELLATE BIO BV
18049903 TDP-43 MODULATING AGENTS AND USES THEREOF Non-Final OA UNITED STATES GOVERNMENT
17923659 METHOD OF MODIFYING A YEAST STRAIN, MODIFIED YEAST STRAINS OBTAINED THEREBY AND USES THEREOF Non-Final OA STELLENBOSCH UNIVERSITY
17775626 USE OF CAS9 PROTEIN FROM THE BACTERIUM PASTEURELLA PNEUMOTROPICA Final Rejection JOINT STOCK COMPANY "BIOCAD"
17811414 TUNABLE TRANSPOSON SYSTEMS Non-Final OA Aridis Pharmaceuticals, Inc.
17615427 USES OF TREM COMPOSITIONS TO MODULATE TRNA POOLS Final Rejection FLAGSHIP PIONEERING, INC.
17423700 TREM COMPOSITIONS AND USES THEREOF Non-Final OA FLAGSHIP PIONEERING, INC.
17995223 GENOME EDITING METHOD BASED ON CRISPR/CAS9 SYSTEM AND USE THEREOF Final Rejection CHUNGANG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
17627853 Methods to determine the effect of an agent on mammalian embryonic development Final Rejection Toxys B.V.
17625433 FUNCTIONAL NUCLEIC ACID MOLECULES UPREGULATING THE TRANSLATION OF A FRATAXIN MRNA Non-Final OA Scuola Internazionale Superiore Studi Internazionale Superiore Di Studi Avanzati - SISSA

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