Prosecution Insights
Last updated: October 02, 2026

Children's Hospital Medical Center

Technology area: Biotechnology & Pharmaceuticals

23 pending office actions • 14 art units • 23 examiners • 0 of 23 (0%) have an AI response strategy ready • 15 patents granted in the last 365 days

Analysis

Children’S Hospital Medical Center has 1 pending office action within the Biotechnology & Pharmaceuticals technology area. This action is assigned to 1 distinct examiner, Emily Ann Cordas. The portfolio's current activity is limited to 1 distinct art unit, which indicates a very specific technical focus for this pending matter. Emily Ann Cordas is the busiest examiner, as she is responsible for the 1 pending office action.

Because there is only 1 pending office action, Emily Ann Cordas manages the entirety of the company's current pending workload. The concentration of the 1 pending office action within 1 distinct art unit means that prosecution is highly localized. Practitioners should tailor their approach to the specific standards of this 1 distinct art unit and the individual preferences of Emily Ann Cordas to successfully resolve the pending matter.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

23
Total Pending OAs
16
Non-Final OAs
5
Final Rejections
2
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 6 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

3
Overdue
0
Due this week
0
Due this month
0
Due in next 60 days
3
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 6 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (3)Due later (3)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

15
Hard (65%)
8
Medium (35%)
0
Easy (0%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 only1 (4%)
§101 + other3 (13%)
§103 only4 (17%)
§102 only2 (9%)
Double-patenting + other2 (9%)
Multi-statute (no §101)11 (48%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

18
Life Sciences
78% of docket
0
Information Tech
0% of docket
1
Communications
4% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
4
Business / Other
17% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

230 h
Manual time on pending OAs
46 h
Time saved (low, 20%)
80 h
Time saved (mid, 35%)
2.0 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
LARSEN, CARL VICTOR 1 69.6% +19.9%
MISHRA, DEEPA 1 29.3% +35.2%
MARVICH, MARIA 1 54.9% +28.1%
WILSON, MICHAEL C 1 41.5% +17.9%
LIPPOLIS, ALEXANDRA ROSE 1 46.9% +59.0%
AMICK, THOMAS RUSSE 1 73.1% +30.4%
ROGERS, ERIC JASON 1 57.4% +32.6%
STOICA, ELLY GERALD 1 66.9% +22.5%
MONTANARI, DAVID A 1 64.7% +49.0%
CHEN, STACY BROWN 1 66.1% +40.6%

Hard Cases (15)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17919030 Systems and Methods for Quantification of Liver Fibrosis with MRI and Deep Learning TIEU, BENNY QUOC 121d overdue
17421908 COMPOSITIONS AND METHODS FOR TREATMENT OF A MALABSORPTIVE DISORDER REGLAS, GILLIAN CHELSEA 91d overdue
18250996 PSEUDOTYPED PARTICLES, MODIFIED CELLS, RELATED COMPOSITIONS, AND RELATED METHODS O'NEILL, MARISOL ANN 32d overdue
18104055 NPERSEVERE: BIOMARKERS ESTIMATING BASELINE MORTALITY RISK FOR NEONATAL SEPSIS AND NECROTIZING ENTEROCOLITIS IVICH, FERNANDO NMN 62d
18915716 METHODS FOR PREDICTING AUTOIMMUNITY POST GENE THERAPY MISHRA, DEEPA —
18847004 DELIVERY METHODS USING PLATELETS MARVICH, MARIA —
18737201 SELF-INACTIVATING LENTIVIRAL VECTOR ENCODING BETA- OR GAMMA-GLOBIN WILSON, MICHAEL C —
18415949 INTEIN TECHNOLOGY TO DELIVER ABCA3 LIPID TRANSPORTER FOR ABCA3 DEFICIENCY LIPPOLIS, ALEXANDRA ROSE —

Interview Candidates (10)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18276905 INFLUENZA VACCINE COMPOSITIONS AND METHODS OF USING SAME CHEN, STACY BROWN 63d
19063450 BIOMETRIC-BASED VIDEO GAME CONTROL SYSTEM AND METHODS THEREOF LARSEN, CARL VICTOR —
18915716 METHODS FOR PREDICTING AUTOIMMUNITY POST GENE THERAPY MISHRA, DEEPA —
18847004 DELIVERY METHODS USING PLATELETS MARVICH, MARIA —
18737201 SELF-INACTIVATING LENTIVIRAL VECTOR ENCODING BETA- OR GAMMA-GLOBIN WILSON, MICHAEL C —
18415949 INTEIN TECHNOLOGY TO DELIVER ABCA3 LIPID TRANSPORTER FOR ABCA3 DEFICIENCY LIPPOLIS, ALEXANDRA ROSE —
18578381 DIFFERENTIAL CXCR4 EXPRESSION ON HEMATOPOIETIC PROGENITOR CELLS VERSUS STEM CELLS DIRECTS HOMING AND LONG-TERM ENGRAFTMENT AMICK, THOMAS RUSSE —
18573954 STRUCTURALLY COMPLETE ORGANOIDS ROGERS, ERIC JASON —

Top Art Units

Art UnitApps
1638 3
1632 3
1633 2
1699 1
1647 1
1672 1
1626 1
1655 1
1758 1
1631 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
19063450 BIOMETRIC-BASED VIDEO GAME CONTROL SYSTEM AND METHODS THEREOF LARSEN, CARL VICTOR — §103 Non-Final OA — Pending Feb 26, 2025
18915716 METHODS FOR PREDICTING AUTOIMMUNITY POST GENE THERAPY MISHRA, DEEPA — §101§103§112 Non-Final OA — Pending Oct 15, 2024
18847004 DELIVERY METHODS USING PLATELETS MARVICH, MARIA — §102§103§112 Non-Final OA — Pending Sep 13, 2024
18737201 SELF-INACTIVATING LENTIVIRAL VECTOR ENCODING BETA- OR GAMMA-GLOBIN WILSON, MICHAEL C 1638 §103§112 Non-Final OA — Pending Jun 07, 2024
18415949 INTEIN TECHNOLOGY TO DELIVER ABCA3 LIPID TRANSPORTER FOR ABCA3 DEFICIENCY LIPPOLIS, ALEXANDRA ROSE — §103§112 Non-Final OA — Pending Jan 18, 2024
18578381 DIFFERENTIAL CXCR4 EXPRESSION ON HEMATOPOIETIC PROGENITOR CELLS VERSUS STEM CELLS DIRECTS HOMING AND LONG-TERM ENGRAFTMENT AMICK, THOMAS RUSSE 1638 §102 Non-Final OA — Pending Jan 11, 2024
18573954 STRUCTURALLY COMPLETE ORGANOIDS ROGERS, ERIC JASON 1699 §102§112 Non-Final OA — Pending Dec 22, 2023
18380877 COMPOSITIONS AND METHODS FOR TREATMENT OF PEDIATRIC PAIN STOICA, ELLY GERALD 1647 DPOther Non-Final OA — Pending Oct 17, 2023
18473619 COLONIC ORGANOIDS AND METHODS OF MAKING AND USING SAME MONTANARI, DAVID A 1632 §101§103Other Non-Final OA — Pending Sep 25, 2023
18276905 INFLUENZA VACCINE COMPOSITIONS AND METHODS OF USING SAME CHEN, STACY BROWN 1672 §102§103§112DPOther Final Rejection 63d Pending Aug 11, 2023
18224632 COMPOSITIONS AND METHODS FOR THE TREATMENT OF HPV-ASSOCIATED DISEASE STATES HAVLIN, ROBERT H 1626 §102§103§112 Non-Final OA — Pending Jul 21, 2023
18333934 Microspheres Containing Decellularized Donor Tissue and Their Use in Fabricating Polymeric Structures BOECKELMAN, JACOB A 1655 §103 Non-Final OA 62d Pending Jun 13, 2023
18039391 ENHANCED NANOPARTICLE DELIVERY SYSTEMS KELLY, ROBERT M 1638 §102 Non-Final OA — Pending May 30, 2023
18252813 REFINED USES OF GABA A RECEPTOR MODULATORS IN TREATMENT OF FRAGILE X SYNDROME WHITE, DENNIS MICHAEL 1758 §102§103Other Final Rejection — Pending May 12, 2023
18250996 PSEUDOTYPED PARTICLES, MODIFIED CELLS, RELATED COMPOSITIONS, AND RELATED METHODS O'NEILL, MARISOL ANN 1633 §102§103 Final Rejection 32d overdue Pending Apr 28, 2023
18027900 RAFT CULTURES AND METHODS OF MAKING THEREOF MIANO, JOSEPH PAUL 1631 §103§112 Final Rejection — Pending Mar 22, 2023
18104055 NPERSEVERE: BIOMARKERS ESTIMATING BASELINE MORTALITY RISK FOR NEONATAL SEPSIS AND NECROTIZING ENTEROCOLITIS IVICH, FERNANDO NMN 1678 §103§112Other Non-Final OA 62d Pending Jan 31, 2023
17997264 Precision Dosing Regimen GU, QINHUA 1633 §103 Non-Final OA — Pending Oct 27, 2022
17919030 Systems and Methods for Quantification of Liver Fibrosis with MRI and Deep Learning TIEU, BENNY QUOC 2682 §101 Non-Final OA 121d overdue Pending Oct 14, 2022
17634148 METHODS FOR MAKING ORGANOID COMPOSITIONS BEHARRY, ZANNA MARIA 1632 §101§103§112Other Non-Final OA — Pending Feb 09, 2022
17627613 METHOD OF TREATING NEOPLASTIC DISEASES WITH A CDC42-SPECIFIC INHIBITOR PUTTLITZ, KARL J 1646 §103 Final Rejection — Pending Jan 14, 2022
17617165 RATIONAL THERAPEUTIC TARGETING OF ONCOGENIC IMMUNE SIGNALING STATES IN MYELOID MALIGNANCIES VIA THE UBIQUITIN CONJUGATING ENZYME UBE2N PATTERSON, SARAH COOPER 1675 §103§112 Non-Final OA — Pending Dec 07, 2021
17421908 COMPOSITIONS AND METHODS FOR TREATMENT OF A MALABSORPTIVE DISORDER REGLAS, GILLIAN CHELSEA 1632 §103§112 Non-Final OA 91d overdue Pending Jul 09, 2021

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