Prosecution Insights
Prosecution Insights
33 pending office actions • 5 clients • 32 examiners • 28 art units • 0 of 33 (0%) have an AI response strategy ready • 48 patents granted in the last 365 days
Based on the USPTO statutory response window for each pending office action. 33 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 33 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §103 only | 13 (39%) |
| §102 only | 3 (9%) |
| §112 only | 7 (21%) |
| No statute on record | 10 (30%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| QIAN, SHIZHI | 2 | 61.7% | +48.4% |
| BERTOGLIO, VALARIE E | 1 | 64.2% | +29.6% |
| CONNORS, ALEXANDRA F | 1 | 23.5% | +44.0% |
| ILAGAN, VINCENT CAESAR | 1 | 41.7% | +63.6% |
| HOLLAND, PAUL J | 1 | 57.5% | +64.7% |
| SINES, BRIAN J | 1 | 80.4% | +4.6% |
| BARNETT, JACK KENSINGTON | 1 | 76.5% | +20.8% |
| JARRELL, NOBLE E | 1 | 81.3% | +9.0% |
| WOOLWINE, SAMUEL C | 1 | 61.0% | +20.0% |
| HE, AMY | 1 | 81.4% | +4.0% |
Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 3 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18442367 | SCALE-UP OF MICROFLUIDIC DEVICES | SINES, BRIAN J | 9d overdue |
| 18365045 | APPARATUSES FOR CELL MAPPING VIA IMPEDANCE MEASUREMENTS AND METHODS TO OPERATE THE SAME | HE, AMY | 26d |
| 18286740 | E3 LIGASE BINDERS AND USES THEREOF | JARRELL, NOBLE E | 28d |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 1 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 19361681 | METHODS AND COMPOSITIONS FOR PRODUCING GRANULOSA-LIKE CELLS | CONNORS, ALEXANDRA F | 13d |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18641299 | ADENOSINE NUCLEOBASE EDITORS AND USES THEREOF | HOLLAND, PAUL J | 77d overdue |
| 18569809 | LOCAL SENSING AND CONTROL OF PH FOR PARALLELIZED SYNTHESIS | QIAN, SHIZHI | 58d overdue |
| 18267989 | APPLICATIONS, METHODS, AND TOOLS FOR DEVELOPMENT, RAPID PREPARATION AND DEPOSITION OF A NANOCOMPOSITE COATING ON SURFACES FOR DIAGNOSTIC DEVICES INCLUDING ELECTROCHEMICAL SENSORS | QIAN, SHIZHI | 42d overdue |
| 19361182 | METHODS AND COMPOSITIONS FOR PRODUCING GRANULOSA-LIKE CELLS | BERTOGLIO, VALARIE E | 8d |
| 19361681 | METHODS AND COMPOSITIONS FOR PRODUCING GRANULOSA-LIKE CELLS | CONNORS, ALEXANDRA F | 13d |
| 18462354 | METHODS OF IDENTIFYING COMBINATIONS OF TRANSCRIPTION FACTORS | WOOLWINE, SAMUEL C | 14d |
| 18512860 | FAULT-TOLERANT QUANTUM COMPUTATION | BARNETT, JACK KENSINGTON | 56d |
| 19057629 | SYSTEMS AND METHODS FOR PERFORMING MEDICAL TASKS USING A MEDICAL ARTIFICIAL INTELLIGENCE SYSTEM | ILAGAN, VINCENT CAESAR | 79d |
| Client (Assignee) | Pending OAs |
|---|---|
| Harvard University | 29 |
| QuEra Computing Incorporated | 1 |
| Vesigen, Inc. | 1 |
| Eisai | 1 |
| THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 1 |
| Art Unit | Apps |
|---|---|
| 1636 | 3 |
| 1656 | 2 |
| 1795 | 2 |
| 1699 | 2 |
| 1632 | 1 |
| 1634 | 1 |
| 3686 | 1 |
| 1796 | 1 |
| 2111 | 1 |
| 1681 | 1 |
| App # | Title | Client | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|---|
| 19361182 | METHODS AND COMPOSITIONS FOR PRODUCING GRANULOSA-LIKE CELLS | President and Fellows of Harvard College | BERTOGLIO, VALARIE E | 1632 | Other | Non-Final OA | 8d | Pending | Oct 17, 2025 |
| 19361681 | METHODS AND COMPOSITIONS FOR PRODUCING GRANULOSA-LIKE CELLS | President and Fellows of Harvard College | CONNORS, ALEXANDRA F | 1634 | Other | Non-Final OA | 13d | Pending | Oct 17, 2025 |
| 19057629 | SYSTEMS AND METHODS FOR PERFORMING MEDICAL TASKS USING A MEDICAL ARTIFICIAL INTELLIGENCE SYSTEM | President and Fellows of Harvard College | ILAGAN, VINCENT CAESAR | 3686 | §103 | Non-Final OA | 79d | Pending | Feb 19, 2025 |
| 18641299 | ADENOSINE NUCLEOBASE EDITORS AND USES THEREOF | President and Fellows of Harvard College | HOLLAND, PAUL J | 1656 | §103 | Non-Final OA | 77d overdue | Pending | Apr 19, 2024 |
| 18442367 | SCALE-UP OF MICROFLUIDIC DEVICES | President and Fellows of Harvard College | SINES, BRIAN J | 1796 | §102 | Non-Final OA | 9d overdue | Pending | Feb 15, 2024 |
| 18569809 | LOCAL SENSING AND CONTROL OF PH FOR PARALLELIZED SYNTHESIS | President and Fellows of Harvard College | QIAN, SHIZHI | 1795 | §103 | Non-Final OA | 58d overdue | Pending | Dec 13, 2023 |
| 18512860 | FAULT-TOLERANT QUANTUM COMPUTATION | Quera Computing Incorporated | BARNETT, JACK KENSINGTON | 2111 | §112 | Non-Final OA | 56d | Pending | Nov 17, 2023 |
| 18286740 | E3 LIGASE BINDERS AND USES THEREOF | President and Fellows of Harvard College | JARRELL, NOBLE E | 1699 | §102 | Non-Final OA | 28d | Pending | Oct 12, 2023 |
| 18462354 | METHODS OF IDENTIFYING COMBINATIONS OF TRANSCRIPTION FACTORS | President and Fellows of Harvard College | WOOLWINE, SAMUEL C | 1681 | §112 | Non-Final OA | 14d | Pending | Sep 06, 2023 |
| 18365045 | APPARATUSES FOR CELL MAPPING VIA IMPEDANCE MEASUREMENTS AND METHODS TO OPERATE THE SAME | President and Fellows of Harvard College | HE, AMY | 2858 | §103 | Final Rejection | 26d | Pending | Aug 03, 2023 |
| 18272933 | ENGINEERED NUCLEIC ACIDS TARGETING LONG NONCODING RNA INVOLVED IN PATHOGENIC INFECTION | President and Fellows of Harvard College | CHONG, KIMBERLY | 1636 | §112 | Non-Final OA | 30d overdue | Pending | Jul 18, 2023 |
| 18267989 | APPLICATIONS, METHODS, AND TOOLS FOR DEVELOPMENT, RAPID PREPARATION AND DEPOSITION OF A NANOCOMPOSITE COATING ON SURFACES FOR DIAGNOSTIC DEVICES INCLUDING ELECTROCHEMICAL SENSORS | President and Fellows of Harvard College | QIAN, SHIZHI | 1795 | §103 | Non-Final OA | 42d overdue | Pending | Jun 16, 2023 |
| 18032105 | WW-DOMAIN-ACTIVATED EXTRACELLULAR VESICLES | President and Fellows of Harvard College | SPANGLER, JOSEPH RANKIN | 1656 | Other | Non-Final OA | 20d | Pending | Apr 14, 2023 |
| 18296350 | METHODS FOR REGULATING BLOOD-CENTRAL NERVOUS SYSTEM (BLOOD-CNS) BARRIER AND USES THEREOF | President and Fellows of Harvard College | SU-TOBON, QIWEN NMN | 1636 | §112 | Non-Final OA | 31d overdue | Pending | Apr 05, 2023 |
| 18030245 | NANOBODY-OGA FUSIONS AND USES THEREOF | President and Fellows of Harvard College | YU, MISOOK | 1641 | Other | Non-Final OA | 96d overdue | Pending | Apr 04, 2023 |
| 18025719 | DUAL-AAV VECTOR DELIVERY OF PCDH15 AND USES THEREOF | President and Fellows of Harvard College | SPENCE, JENNIFER SUZANNE | 1633 | §103 | Final Rejection | 29d | Pending | Mar 10, 2023 |
| 18025749 | RECOMBINANT ADENO ASSOCIATED VIRUS (RAAV) ENCODING GJB2 AND USES THEREOF | President and Fellows of Harvard College | BRETZ, COREY LANE | 1635 | Other | Non-Final OA | 14d | Pending | Mar 10, 2023 |
| 18066878 | NUCLEOBASE EDITORS COMPRISING NUCLEIC ACID PROGRAMMABLE DNA BINDING PROTEINS | President and Fellows of Harvard College | GOMEZ RODRIGUEZ, JULIO WASHINGTON | 1637 | Other | Final Rejection | 46d overdue | Pending | Dec 15, 2022 |
| 18009290 | ARRDC1-MEDIATED MICROVESICLE-BASED DELIVERY TO THE NERVOUS SYSTEM | Vesigen, Inc. | VU, JAKE MINH | 1618 | §103 | Non-Final OA | 52d overdue | Pending | Dec 08, 2022 |
| 18058441 | SYNTHESIS OF HALICHONDRINS | Eisai R&D Management Co., Ltd. | OH, TAYLOR V | 1625 | Other | Non-Final OA | 21d | Pending | Nov 23, 2022 |
| 17926809 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | President and Fellows of Harvard College | CRAIGO, BAHAR ALAWI | 1699 | Other | Final Rejection | 34d | Pending | Nov 21, 2022 |
| 17923891 | METHODS FOR INDUCING BILE ACID SULFOTRANSFERASE SULT2A FOR TREATING METABOLIC DISORDERS | The Brigham And Women'S Hospital, Inc. | REDWOOD, CHRISTOPHER EVAN | 1629 | §112 | Non-Final OA | 5d | Pending | Nov 07, 2022 |
| 17920352 | HIGH-SPEED OPTICAL TARGETING SYSTEMS AND METHODS | President and Fellows of Harvard College | PASKO, NICHOLAS R | 2896 | §102 | Final Rejection | 89d overdue | Pending | Oct 20, 2022 |
| 17965573 | GLYCOLIPID COMPOSITIONS AND METHODS OF USE | President and Fellows of Harvard College | CREWS, JARET JAMES | 1691 | §103 | Final Rejection | 77d overdue | Pending | Oct 13, 2022 |
| 17938273 | MULTIPLEXED SIGNAL AMPLIFICATION | President and Fellows of Harvard College | GUSSOW, ANNE | 1683 | §103 | Non-Final OA | 52d overdue | Pending | Oct 05, 2022 |
| 17880409 | SOFT EXOSUIT FOR ASSISTANCE WITH HUMAN MOTION | President and Fellows of Harvard College | JAYAN, AKHIL ADAI | 3785 | §112 | Non-Final OA | 2d overdue | Pending | Aug 03, 2022 |
| 17858570 | SYSTEM AND METHOD FOR QUANTUM SAMPLING FROM A PROBABILITY DISTRIBUTION | President and Fellows of Harvard College | HOANG, MICHAEL H | 2122 | §103 | Non-Final OA | 15d overdue | Pending | Jul 06, 2022 |
| 17773000 | IMAGE PROCESSING FOR STANDARDIZING SIZE AND SHAPE OF ORGANISMS | President and Fellows of Harvard College | ALFONSO, DENISE G | 2662 | §103 | Non-Final OA | 35d overdue | Pending | Apr 28, 2022 |
| 17770943 | GENOME-SCALE IMAGING OF THE 3D ORGANIZATION AND TRANSCRIPTIONAL ACTIVITY OF CHROMATIN | President and Fellows of Harvard College | TURPIN, ZACHARY MARK | 1682 | Other | Final Rejection | 4d overdue | Pending | Apr 21, 2022 |
| 17613216 | GENE EDITING IN DIVERSE BACTERIA | President and Fellows of Harvard College | REGA, KYLE THOMAS | 1636 | §103 | Non-Final OA | 100d overdue | Pending | Nov 22, 2021 |
| 17289613 | NANOBODY-GLYCAN MODIFYING ENZYME FUSION PROTEINS AND USES THEREOF | President and Fellows of Harvard College | PETRASH, HILARY ANN | 1644 | §112 | Non-Final OA | 138d overdue | Pending | Apr 28, 2021 |
| 16925923 | ENHANCED ELECTROCHEMICAL DETECTION USING NANOPARTICLES AND PRECIPITATION | President and Fellows of Harvard College | VOLKOV, ALEXANDER ALEXANDROVIC | 1677 | Other | Non-Final OA | 113d overdue | Pending | Jul 10, 2020 |
| 16614133 | BIOFERTILIZER AND METHODS OF MAKING AND USING SAME | President and Fellows of Harvard College | REGLAS, GEORGIANA C | 1651 | §103 | Non-Final OA | 23d overdue | Pending | Nov 15, 2019 |
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