Prosecution Insights
Last updated: October 25, 2026

Wayne State University

Technology areas: Biotechnology & Pharmaceuticals • Chemistry & Materials • Medical Devices & Mechanical Engineering

20 pending office actions • 18 art units • 20 examiners • 0 of 20 (0%) have an AI response strategy ready • 23 patents granted in the last 365 days

Analysis

Wayne State University has 22 pending office actions in Biotechnology & Pharmaceuticals. The matters are distributed among 22 distinct examiners and 20 art units, indicating a broad prosecution program with little examiner concentration. The art-unit distribution still provides a useful structure for reviewing recurring technical and claim issues.

ZHANG, LEI is the busiest examiner, with 1 pending matter. No examiner accounts for more than that figure, so a single-examiner strategy would not address the portfolio's breadth. Counsel should maintain application-level response plans, supplemented by art-unit reviews that identify common biotechnology and pharmaceutical examination patterns.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

20
Total Pending OAs
7
Non-Final OAs
13
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 8 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

2
Overdue
0
Due this week
2
Due this month
2
Due in next 60 days
2
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 8 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (2)Due ≤ 30 days (2)Due ≤ 60 days (2)Due later (2)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

11
Hard (55%)
8
Medium (40%)
1
Easy (5%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other2 (10%)
§103 only7 (35%)
§112 only1 (5%)
Double-patenting + other1 (5%)
Multi-statute (no §101)9 (45%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

13
Life Sciences
65% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
2
Semiconductors
10% of docket
5
Mechanical / Eng
25% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

200 h
Manual time on pending OAs
40 h
Time saved (low, 20%)
70 h
Time saved (mid, 35%)
1.8 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
ZHANG, LEI 1 13.3% +100.0%
HOUGH, JESSANDRA F 1 45.8% +35.3%
CABRAL, ROBERT S 1 62.8% +32.3%
PARENDO, KEVIN A 1 72.3% +11.5%
REILLY, SOPHIA JANE 1 60.0% +49.4%
GAMBETTA, KELLY M 1 71.8% +33.0%
HAN, SETH 1 59.6% +27.1%
WAX, ROBERT A 1 25.7% +3.9%
PHAM, KATHERINE-PH MINH 1 59.8% +49.7%
MCCLURE, CHRISTINA D 1 29.9% +33.1%

Hard Cases (13)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17862825 METHODS AND COMPOSITIONS RELATING TO HOT-START, ONE-STEP, REVERSE TRANSCRIPTION-COUPLED PCR CHANDRA, GYAN 44d overdue
17434692 INDUCTION OF HIGHLY EFFICACIOUS ANTI-TUMOR AND IMMUNE MODULATING ACTIVITY: CELL-FREE OFF THE SHELF THERAPEUTIC MODALITY BUTTICE, AUDREY L 34d
18858953 METHOD AND APPARATUS FOR MAGNETIC RESONANCE (MR) CONTRAST AGENTS ZHANG, LEI 69d
18252416 COMPOSITIONS AND METHODS FOR INHIBITION OF TISSUE ADHESION WASHVILLE, JEFFREY D 84d
18910860 DEVICE AND METHOD FOR DETECTING ORTHOSTATIC VITAL SIGNS HOUGH, JESSANDRA F —
18755249 METHODS OF FORMING STACKED INTEGRATED CIRCUITS USING SELECTIVE THERMAL ATOMIC LAYER DEPOSITION ON CONDUCTIVE CONTACTS AND STRUCTURES FORMED USING THE SAME PARENDO, KEVIN A —
18601338 INHERENTLY SELECTIVE THERMAL ATOMIC LAYER DEPOSITION OF COPPER METAL FILMS GAMBETTA, KELLY M —
18690241 METHODS AND COMPOSITIONS TO REDUCE CELLULAR DEPOSITION, AND HYDROCEPHALUS SHUNT FAILURE WAX, ROBERT A —

Interview Candidates (9)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18690227 VENTRICULAR CATHETERS AND OTHER EMBODIMENTS HAN, SETH 24d overdue
18690225 SOLID STATE SHUNT VALVE WITH ACTIVE OUTFLOW REGULATOR, VENTRICULAR CATHETERS, AND OTHER EMBODIMENTS PHAM, KATHERINE-PH MINH 27d
18858953 METHOD AND APPARATUS FOR MAGNETIC RESONANCE (MR) CONTRAST AGENTS ZHANG, LEI 69d
18910860 DEVICE AND METHOD FOR DETECTING ORTHOSTATIC VITAL SIGNS HOUGH, JESSANDRA F —
18780262 METHOD OF TREATMENT FOR SOLID TUMORS CONTAINING HYPOXIA AND/OR STROMA FEATURES CABRAL, ROBERT S —
18755249 METHODS OF FORMING STACKED INTEGRATED CIRCUITS USING SELECTIVE THERMAL ATOMIC LAYER DEPOSITION ON CONDUCTIVE CONTACTS AND STRUCTURES FORMED USING THE SAME PARENDO, KEVIN A —
18742267 COMPOSITIONS AND METHODS RELATING TO USE OF PHOSPHATIDIC ACID TO RESCUE FETAL ALCOHOL SPECTRUM DISORDER (FASD) GROWTH RESTRICTION AND BLOOD VESSEL CONSTRICTION REILLY, SOPHIA JANE —
18601338 INHERENTLY SELECTIVE THERMAL ATOMIC LAYER DEPOSITION OF COPPER METAL FILMS GAMBETTA, KELLY M —

Top Art Units

Art UnitApps
1718 2
3781 2
3798 1
3796 1
1614 1
2896 1
1627 1
1615 1
2881 1
1779 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18858953 METHOD AND APPARATUS FOR MAGNETIC RESONANCE (MR) CONTRAST AGENTS ZHANG, LEI 3798 §103 Final Rejection 69d Pending Oct 22, 2024
18910860 DEVICE AND METHOD FOR DETECTING ORTHOSTATIC VITAL SIGNS HOUGH, JESSANDRA F 3796 §101§103§112 Non-Final OA — Pending Oct 09, 2024
18780262 METHOD OF TREATMENT FOR SOLID TUMORS CONTAINING HYPOXIA AND/OR STROMA FEATURES CABRAL, ROBERT S 1614 §112DP Non-Final OA — Pending Jul 22, 2024
18755249 METHODS OF FORMING STACKED INTEGRATED CIRCUITS USING SELECTIVE THERMAL ATOMIC LAYER DEPOSITION ON CONDUCTIVE CONTACTS AND STRUCTURES FORMED USING THE SAME PARENDO, KEVIN A 2896 §102§103§112 Non-Final OA — Pending Jun 26, 2024
18742267 COMPOSITIONS AND METHODS RELATING TO USE OF PHOSPHATIDIC ACID TO RESCUE FETAL ALCOHOL SPECTRUM DISORDER (FASD) GROWTH RESTRICTION AND BLOOD VESSEL CONSTRICTION REILLY, SOPHIA JANE 1627 §103 Final Rejection — Pending Jun 13, 2024
18601338 INHERENTLY SELECTIVE THERMAL ATOMIC LAYER DEPOSITION OF COPPER METAL FILMS GAMBETTA, KELLY M 1718 §102§103 Final Rejection — Pending Mar 11, 2024
18690227 VENTRICULAR CATHETERS AND OTHER EMBODIMENTS HAN, SETH 3781 §103 Final Rejection 24d overdue Pending Mar 07, 2024
18690241 METHODS AND COMPOSITIONS TO REDUCE CELLULAR DEPOSITION, AND HYDROCEPHALUS SHUNT FAILURE WAX, ROBERT A 1615 §102§103 Non-Final OA — Pending Mar 07, 2024
18690225 SOLID STATE SHUNT VALVE WITH ACTIVE OUTFLOW REGULATOR, VENTRICULAR CATHETERS, AND OTHER EMBODIMENTS PHAM, KATHERINE-PH MINH 3781 §103 Final Rejection 27d Pending Mar 07, 2024
18438175 ATOMIC LAYER DEPOSITION OF GROUP FIFTEEN MATERIALS MCCLURE, CHRISTINA D 1718 §103 Final Rejection — Pending Feb 09, 2024
18409972 Systems, Methods and Computer Program Products for Charging Autonomous Wireless Sensors in Subsurface Environments GASSEN, CHRISTOPHER J 2881 §103§112 Final Rejection — Pending Jan 11, 2024
18515982 METAL CHELATORS RAMDHANIE, BOBBY 1779 §102§103§112 Non-Final OA — Pending Nov 21, 2023
18252416 COMPOSITIONS AND METHODS FOR INHIBITION OF TISSUE ADHESION WASHVILLE, JEFFREY D 1766 §103§112 Non-Final OA 84d Pending May 10, 2023
18135836 Methods and Compositions for Cells Expressing a Chimeric Intracellular Signaling Molecule ARON, KIMBERLY A 1633 §103§112 Final Rejection — Pending Apr 18, 2023
18028150 SYSTEMS AND METHODS FOR PREDICTING AND PREVENTING BLEEDING AND OTHER ADVERSE EVENTS COOK, CHRISTOPHER L 3797 §112 Final Rejection 53d Pending Mar 23, 2023
18085879 RECHARGEABLE BATTERIES USING IONIC LIQUID BASED ELECTROLYTES SMITH, NICHOLAS A 1752 §102§103§112 Final Rejection — Pending Dec 21, 2022
17862825 METHODS AND COMPOSITIONS RELATING TO HOT-START, ONE-STEP, REVERSE TRANSCRIPTION-COUPLED PCR CHANDRA, GYAN 1674 §101§103 Final Rejection 44d overdue Pending Jul 12, 2022
17636107 IN VIVO IMMUNOIMAGING OF INTERLEUKIN-12 YOUNG, MICAH PAUL 1618 §103 Final Rejection 12d Pending Feb 17, 2022
17434692 INDUCTION OF HIGHLY EFFICACIOUS ANTI-TUMOR AND IMMUNE MODULATING ACTIVITY: CELL-FREE OFF THE SHELF THERAPEUTIC MODALITY BUTTICE, AUDREY L 1647 §103§112 Final Rejection 34d Pending Aug 27, 2021
16826010 ACTIVITY-DEPENDENT GENE PAIRS AS THERAPEUTIC TARGETS AND METHODS AND DEVICES TO IDENTIFY THE SAME RYAN, DOUGLAS CHARLES 1635 §103 Non-Final OA — Pending Mar 20, 2020

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Frequently Asked Questions

How many pending USPTO office actions does Wayne State University have?

Wayne State University has 20 pending office actions as of October 2026, spread across 18 art units and 20 examiners.

Which USPTO examiner handles the most Wayne State University applications?

Lei Zhang has the most, with 1 of Wayne State University's pending office actions.

What technology area are Wayne State University's patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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