Prosecution Insights
Last updated: May 29, 2026

Johnson, Marcou, Isaacs & Nix, LLC

34 pending office actions • 12 clients • 31 examiners • 25 art units • 0 of 34 (0%) have an AI response strategy ready • 37 patents granted in the last 365 days

Portfolio Summary

34
Total Pending OAs
23
Non-Final OAs
11
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 34 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

13
Overdue
0
Due this week
12
Due this month
7
Due in next 60 days
2
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 34 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (13)Due ≤ 30 days (12)Due ≤ 60 days (7)Due later (2)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

1
Hard (3%)
19
Medium (56%)
8
Easy (24%)
6
Unknown (18%)

Rejection Statute Mix

BucketCases
§101 only1 (3%)
§103 only17 (50%)
§102 only1 (3%)
§112 only8 (24%)
Double-patenting + other1 (3%)
No statute on record6 (18%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

32
Life Sciences
94% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
1
Semiconductors
3% of docket
1
Mechanical / Eng
3% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

340 h
Manual time on pending OAs
68 h
Time saved (low, 20%)
119 h
Time saved (mid, 35%)
3.0 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
RAMIREZ, DELIA M 3 65.0% +56.5%
VISHNYAKOVA, ELENA VLADIMIROVNA 2 59.3% +73.3%
KUCKLA, ANNA GRACE 1 51.3% +52.1%
GRAHAM, ANDREW D 1 59.7% +21.9%
WANG, XIAOBEI 1 64.9% +48.4%
ANDREWS, MICHAEL 1 64.0% +24.7%
PAGE, BRENT T 1 82.5% +10.7%
OGDEN JR, NECHOLUS 1 69.8% +23.7%
ALLEN, MICHAEL D 1 32.6% +48.7%
FEELY, MICHAEL J 1 75.1% +41.7%

Hard Cases (1)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
17921417 METHOD OF DIAGNOSING A BIOLOGICAL ENTITY, AND DIAGNOSTIC DEVICE ERICKSON, BENNETT S 26d overdue

Interview Candidates (13)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18628213 NANOPOROUS ALLOYS WANG, XIAOBEI 140d overdue
18688206 STATOR WITH PERMANENT PROTECTIVE BARRIER SEALING ANDREWS, MICHAEL 70d overdue
18990537 BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES VISHNYAKOVA, ELENA VLADIMIROVNA 66d overdue
18277904 SURFACTANT COMPOSITIONS OGDEN JR, NECHOLUS 8d overdue
18216135 COMPOSITION AND METHOD FEELY, MICHAEL J 4d overdue
16450852 NOVEL CRISPR ENZYMES AND SYSTEMS RAMIREZ, DELIA M 9d
16450825 NOVEL CRISPR ENZYMES AND SYSTEMS RAMIREZ, DELIA M 14d
19329060 VERY LONG CHAIN FATTY ACIDS FOR TREATMENT AND ALLEVIATION OF DISEASES KUCKLA, ANNA GRACE 23d

Client Portfolio (12 clients)

Top Art Units

Art UnitApps
16524
16912
16712
16352
16722
16562
16812
16261
17421
17841

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
19329060 VERY LONG CHAIN FATTY ACIDS FOR TREATMENT AND ALLEVIATION OF DISEASES Epax Norway AS KUCKLA, ANNA GRACE 1626 §103 Non-Final OA 23d Pending Sep 15, 2025
18990537 BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES The Brigham And Women'S Hospital, Inc. VISHNYAKOVA, ELENA VLADIMIROVNA 1691 §103 Final Rejection 66d overdue Pending Dec 20, 2024
18849107 THREE DIMENSIONAL PRINTING PROCESS FLOW MANAGEMENT AND SUPPORT SYSTEMS Azul 3D, Inc. GRAHAM, ANDREW D 1742 §103 Non-Final OA 53d Pending Sep 20, 2024
18628213 NANOPOROUS ALLOYS VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY WANG, XIAOBEI 1784 §103 Non-Final OA 140d overdue Pending Apr 05, 2024
18688206 STATOR WITH PERMANENT PROTECTIVE BARRIER SEALING Elaphe Propulsion Technologies, Ltd. ANDREWS, MICHAEL 2834 §112 Non-Final OA 70d overdue Pending Feb 29, 2024
18430788 MULTI-EFFECTOR CRISPR BASED DIAGNOSTIC SYSTEMS President and Fellows of Harvard College PAGE, BRENT T 1663 Other Non-Final OA 41d Pending Feb 02, 2024
18277904 SURFACTANT COMPOSITIONS Lankem Ltd. OGDEN JR, NECHOLUS 1761 §102 Non-Final OA 8d overdue Pending Aug 18, 2023
18277612 METHODS OF STRATIFYING AND TREATING CORONAVIRUS INFECTION University of Mississippi Medical Center ALLEN, MICHAEL D 1671 §103 Non-Final OA 53d Pending Aug 17, 2023
18216135 COMPOSITION AND METHOD Lankem Ltd. FEELY, MICHAEL J 1766 §103 Non-Final OA 4d overdue Pending Jun 29, 2023
18334074 TYPE VI CRISPR ORTHOLOGS AND SYSTEMS President and Fellows of Harvard College KONOPKA, CATHERINE ANNE 1635 Other Non-Final OA 9d Pending Jun 13, 2023
18032868 REPROGRAMMABLE ISCB NUCLEASES AND USES THEREOF Massachusetts Institute Of Technology SU-TOBON, QIWEN NMN 1636 Other Non-Final OA 9d Pending Apr 20, 2023
18248199 HELITRON MEDIATED GENETIC MODIFICATION Massachusetts Institute Of Technology LIPPOLIS, ALEXANDRA ROSE 1637 §103 Non-Final OA 25d overdue Pending Apr 06, 2023
18026866 CELL-FREE ANTIBODY ENGINEERING PLATFORM AND NEUTRALIZING ANTIBODIES FOR SARS-COV-2 Massachusetts Institute Of Technology BOESEN, AGNIESZKA 1672 §112 Non-Final OA 22d Pending Mar 17, 2023
17999364 BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES The Brigham And Women'S Hospital, Inc. VISHNYAKOVA, ELENA VLADIMIROVNA 1691 Other Final Rejection 53d Pending Nov 18, 2022
17921417 METHOD OF DIAGNOSING A BIOLOGICAL ENTITY, AND DIAGNOSTIC DEVICE Oxford University Innovation Limited ERICKSON, BENNETT S 3683 §101 Final Rejection 26d overdue Pending Oct 26, 2022
17916087 SEQUENCING-BASED POPULATION SCALE SCREENING Massachusetts Institute Of Technology YAMASAKI, ROBERT J 1657 §103 Final Rejection 34d Pending Sep 30, 2022
17786168 GENOME EDITING USING REVERSE TRANSCRIPTASE ENABLED AND FULLY ACTIVE CRISPR COMPLEXES Massachusetts Institute Of Technology LEE, JAE W 1656 §103 Final Rejection 33d Pending Jun 16, 2022
17707951 ENGINEERED ADENO-ASSOCIATED VIRUS CAPSIDS Massachusetts Institute Of Technology WEHBE, ANNE MARIE SABRINA 1634 §103 Non-Final OA 99d overdue Pending Mar 30, 2022
17764509 ENGINEERED MUSCLE TARGETING COMPOSITIONS Massachusetts Institute Of Technology CHESTNUT, BARRY A 1672 DPOther Non-Final OA 77d Pending Mar 28, 2022
17616621 CRISPR SYSTEM HIGH THROUGHPUT DIAGNOSTIC SYSTEMS AND METHODS The General Hospital Corporation POHNERT, STEVEN C 1683 Other Non-Final OA 53d Pending Dec 03, 2021
17614602 METHODS AND COMPOSITIONS FOR MODULATING IMMUNE RESPONSES Massachusetts Institute Of Technology PARKIN, JEFFREY S 1671 §112 Final Rejection 28d Pending Nov 29, 2021
17600799 METHODS AND COMPOSITIONS FOR CELL THERAPY The Brigham And Women'S Hospital, Inc. JOHNSON, ALLISON MARIE 1638 §103 Non-Final OA 14d Pending Oct 01, 2021
17439063 CRISPR EFFECTOR SYSTEM BASED MULTIPLEX DIAGNOSTICS President and Fellows of Harvard College SISSON, BRADLEY L 1682 §103 Final Rejection 29d Pending Sep 14, 2021
17294179 CRISPR SYSTEM BASED DROPLET DIAGNOSTIC SYSTEMS AND METHODS The General Hospital Corporation GIAMMONA, FRANCESCA FILIPPA 1681 §103 Non-Final OA 3d overdue Pending May 14, 2021
17273999 NUCLEIC ACID ASSEMBLIES FOR USE IN TARGETED DELIVERY Massachusetts Institute Of Technology SMALL, KATHERINE R 1633 §103 Final Rejection 20d Pending Mar 05, 2021
17254886 CRISPR DOUBLE NICKASE BASED AMPLIFICATION COMPOSITIONS, SYSTEMS, AND METHODS President and Fellows of Harvard College GREENE, CAROLYN LEE 1681 §112 Non-Final OA 30d overdue Pending Dec 22, 2020
17085937 BACTERIAL DEFENSE SYSTEMS AND METHODS OF IDENTIFYING THEREOF Massachusetts Institute Of Technology RYAN, DOUGLAS CHARLES 1635 §112 Non-Final OA 3d overdue Pending Oct 30, 2020
16936197 FUNCTIONALIZED SOLID SUPPORT Massachusetts Institute Of Technology BUNKER, AMY M 1684 §103 Non-Final OA 9d overdue Pending Jul 22, 2020
16954032 CAS12A SYSTEMS, METHODS, AND COMPOSITIONS FOR TARGETED RNA BASE EDITING Massachusetts Institute Of Technology HUTSON, RICHARD G 1652 Other Non-Final OA 20d Pending Jun 15, 2020
16772269 CAS12B SYSTEMS, METHODS, AND COMPOSITIONS FOR TARGETED RNA BASE EDITING Massachusetts Institute Of Technology RAMIREZ, DELIA M 1652 §112 Non-Final OA 70d Pending Jun 12, 2020
16756134 SYSTEMS, METHODS, AND COMPOSITIONS FOR TARGETED NUCLEIC ACID EDITING President and Fellows of Harvard College STEADMAN, DAVID J 1656 §103 Non-Final OA 3d overdue Pending Apr 15, 2020
16632332 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASES The General Hospital Corporation STAVROU, CONSTANTINA E 1632 §103 Final Rejection 29d Pending Jan 17, 2020
16450852 NOVEL CRISPR ENZYMES AND SYSTEMS The United States Department of Health and Human Services RAMIREZ, DELIA M 1652 §112 Final Rejection 9d Pending Jun 24, 2019
16450825 NOVEL CRISPR ENZYMES AND SYSTEMS The United States Department of Health and Human Services RAMIREZ, DELIA M 1652 §112 Final Rejection 14d Pending Jun 24, 2019

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