Prosecution Insights
Last updated: October 25, 2026

Klarquist Sparkman, LLP

Technology area: Biotechnology & Pharmaceuticals

368 pending office actions • 130 clients • 330 examiners • 189 art units • 15 of 368 (4%) have an AI response strategy ready

Analysis

KLARQUIST SPARKMAN, LLP has 18129 career applications in Biotechnology & Pharmaceuticals and 366 pending office actions. Those figures show a large historical portfolio accompanied by substantial current prosecution activity in the same technology area.

The resolved allowance rate is 86.57%. Each allowance required an average of 3.11 office actions, indicating that successful matters generally progressed through multiple examination exchanges. The profile can therefore inform both outcome assessment and planning for ongoing prosecution effort.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Quality Metrics (n=18129 apps, methodology: how we score firms)

86.6%
Allowance Rate
n=18129
+0.70σ
Allowance Rate (norm)
n=18129
3.1
OAs to Allowance
n=10936
-0.31σ
OAs to Allow (norm)
n=10936
1030 days
Time to Allowance
n=10936
+9.9pp
Interview Lift
n=18129
22.6%
RCE Rate
n=18129
1.6%
Appeal Rate
n=18129

Rejection Performance (% of received rejections ultimately overcome)

82.5%
§101 Overcome
n=1723
81.8%
§102 Overcome
n=4135
82.0%
§103 Overcome
n=6590
84.2%
§112 Overcome
n=5393

Specialization & Scale

A61K, A61P, C12N
Top CPC Subclasses
19%
Top-3 CPC Share
n=18129
41
Practitioners
n=18129
442.2
Apps / Practitioner
n=18129

Portfolio Summary

368
Total Pending OAs
234
Non-Final OAs
125
Final Rejections
9
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 112 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

54
Overdue
4
Due this week
29
Due this month
13
Due in next 60 days
12
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 112 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (54)Due ≤ 7 days (4)Due ≤ 30 days (29)Due ≤ 60 days (13)Due later (12)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

204
Hard (55%)
127
Medium (35%)
34
Easy (9%)
3
Unknown (1%)

Rejection Statute Mix

BucketCases
§101 only7 (2%)
§101 + other56 (15%)
§103 only92 (25%)
§102 only15 (4%)
§112 only24 (7%)
Double-patenting only10 (3%)
Double-patenting + other20 (5%)
Multi-statute (no §101)141 (38%)
No statute on record3 (1%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

170
Life Sciences
46% of docket
47
Information Tech
13% of docket
23
Communications
6% of docket
43
Semiconductors
12% of docket
77
Mechanical / Eng
21% of docket
8
Business / Other
2% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

3,680 h
Manual time on pending OAs
736 h
Time saved (low, 20%)
1,288 h
Time saved (mid, 35%)
32.2 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
HUNTER, ALVIN A 6 85.7% +2.8%
WANG, JING 5 100.0% +0.0%
SIMMS JR, JOHN ELLIOTT 4 65.3% +12.5%
STOFFA, WYATT A 3 79.3% +22.3%
GILL, RACHEL B 3 65.4% +28.8%
NGUYEN, NAM P 3 54.8% +48.7%
RAEVIS, ROBERT R 2 83.3% +15.3%
WONG, LINDA 2 84.9% +15.5%
CHOI, JAMES J 2 68.3% +44.9%
MCCORD, PAUL C 2 69.3% +25.9%

Quick Wins (6)

Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 6 ordered by deadline are shown.

App #TitleExaminerDue in
18975483 DATA-DRIVEN STRUCTURE EXTRACTION FROM TEXT DOCUMENTS WONG, LINDA —
18792777 IRON TYPE GOLF CLUB HEAD HUNTER, ALVIN A —
18791808 GOLF CLUB HEADS HUNTER, ALVIN A —
18761819 GOLF CLUB HEAD HUNTER, ALVIN A —
18750180 GOLF CLUB HUNTER, ALVIN A —
18515737 GOLF CLUB HEAD WITH VERTICAL CENTER OF GRAVITY ADJUSTMENT HUNTER, ALVIN A —

Hard Cases (204)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18329816 COLDWATER DISEASE VACCINE COMPRISING AN ATTENUATED FLAVOBACTERIUM PSYCHROPHILUM STRAIN GRASER, JENNIFER E 132d overdue
18503854 BIOREMEDIATION USING CO-METABOLISM SUBSTRATES XU, QING 128d overdue
18104703 DEVICE AND METHOD FOR PROCESSING INFORMATION USING A BACKGROUND SERVICE OF AN OPERATING SYSTEM TURK, BROCK E 127d overdue
17637058 COMPOSITIONS AND METHODS FOR IN VIVO GENE EDITING LIPPOLIS, ALEXANDRA ROSE 125d overdue
17007922 AUTOMATIC BITE SETTING FARAJ, LINA AHMAD 103d overdue
18665272 VIRTUAL DENTAL BRIDGE ROSEN, ERIC J 66d overdue
18039202 METHOD OF FORMING A THIN FILM ABDELAZIEZ, YASSER A 60d overdue
18041862 FLEXIBLE DOUBLE-ENDED VIBRATING DEVICE PENG, BO JOSEPH 60d overdue

Interview Candidates (21)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18537626 INTELLIGENT NATURAL LANGUAGE QUERIES VIA LARGE LANGUAGE MODEL AND USER INTERFACE ELEMENT METADATA MCCORD, PAUL C 26d overdue
18275925 ADJUVANTED MUCOSAL SUBUNIT VACCINES FOR PREVENTING SARS-COV-2 TRANSMISSION AND INFECTION GILL, RACHEL B 5d overdue
18380388 COMPOSITIONS AND METHODS FOR ENHANCED FLUORESCENCE NGUYEN, NAM P 26d
18531430 GOLF CLUB HEAD SIMMS JR, JOHN ELLIOTT 29d
18877235 SENSOR HOLDING DEVICE RAEVIS, ROBERT R —
18975483 DATA-DRIVEN STRUCTURE EXTRACTION FROM TEXT DOCUMENTS WONG, LINDA —
18955676 TRANSMISSION ELECTRON MICROSCOPE WITH VARIABLE EFFECTIVE FOCAL LENGTH CHOI, JAMES J —
18942315 METHOD FOR PRESSURE EQUALISATION OF SIMULTANEOUSLY OPERATED COLUMNS RAEVIS, ROBERT R —

Client Portfolio (130 clients)

View all 130 →

Top Art Units

Art UnitApps
288113
371112
37919
37727
16316
37836
16816
16245
21935
16335

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
19640048 ARTICLE OF FOOTWEAR AND SOLE STRUCTURE WITH SENSORY NODE ELEMENTS DISPOSED AT DISCRETE LOCATIONS Nike, Inc. DENKOVIC, HALEY 3732 §102§103§112 Non-Final OA — Pending Apr 06, 2026
19376996 Using Fixed-Weight Language Models to Create and Interact with a Retrieval Index Microsoft Technology Licensing, LLC ZHAO, YU 2169 §101DP Non-Final OA — Pending Nov 02, 2025
19360639 SEGMENTED ARTICLES OF FOOTWEAR Nike, Inc. KAVANAUGH, JOHN T 3732 §102§103 Non-Final OA — Pending Oct 16, 2025
19349863 VEHICLE MOVEMENT TRACKING Q-Free Norge AS KUJUNDZIC, DINO 3658 §101§103Other Non-Final OA — Pending Oct 03, 2025
19342148 HASH-BASED ENCODER DECISIONS FOR VIDEO CODING Microsoft Technology Licensing, LLC PICON-FELICIANO, ANA J 2482 Other Non-Final OA — Pending Sep 26, 2025
19326676 ULTRASOUND TRANSDUCER ASSEMBLY Cordance Medical Inc. RAYMOND, KEITH MICHAEL 3798 §102§103DP Non-Final OA — Pending Sep 11, 2025
19288463 SIGNALING OF STATE INFORMATION FOR A DECODED PICTURE BUFFER AND REFERENCE PICTURE LISTS Microsoft Technology Licensing, LLC HANSELL JR., RICHARD A 2486 §102§112DP Non-Final OA — Pending Aug 01, 2025
19253623 SECURITY SYSTEM Portable Multimedia Ltd. TUN, NAY L 2685 §103§112Other Non-Final OA — Pending Jun 27, 2025
19253404 CONTINUOUS CUSTOM DENTAL RESTORATION MANUFACTURING PROCESS AND SYSTEM James R. Glidewell Dental Ceramics, Inc. SCHIFFMAN, BENJAMIN A 1743 §112Other Non-Final OA — Pending Jun 27, 2025
19249928 ADJUSTING QUANTIZATION/SCALING AND INVERSE QUANTIZATION/SCALING WHEN SWITCHING COLOR SPACES Microsoft Technology Licensing, LLC PHILIPPE, GIMS S 2482 DP Non-Final OA — Pending Jun 25, 2025
19140995 PHASE LOCK DETECTOR Novelda AS HILTUNEN, THOMAS J 2836 §102§103 Non-Final OA — Pending Jun 18, 2025
19242855 PROCESSING OF VIDEO OPERATIONS AS SUBTASKS FOR VIDEO FRAGMENTS Microsoft Technology Licensing, LLC BECKER, JOSEPH W 2483 §102§103 Non-Final OA — Pending Jun 18, 2025
19197829 OCCLUDING PURGE VENTURI SYSTEMS AND METHODS OF USE THEREOF Emerging Acquisitions, LLC COLON MORALES, DAVID 3753 §102§112Other Non-Final OA — Pending May 02, 2025
19182210 SCANNING TIP FOR PHOTOACOUSTIC-ULTRASOUND MINI PROBE ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY LY, TOMMY TAI 3797 §102§103 Non-Final OA — Pending Apr 17, 2025
19120354 PACKET DURATION ESTIMATION Nordic Semiconductor ASA PEREZ, JAMES M 2635 §112 Non-Final OA — Pending Apr 11, 2025
19095982 HELICAL SCAN PHOTOACOUSTIC-ULTRASONIC ENDOSCOPE ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY MOHAMMED, SHAHDEEP 3797 §103 Final Rejection — Pending Mar 31, 2025
19088247 SENSITIVE DATA PROTECTION USING AN AUXILIARY MACHINE-LEARNING TOOL Thia St Co. SARKER, SANCHIT K 2495 §103§112 Non-Final OA — Pending Mar 24, 2025
19088242 FINGERPRINT SECURITY OF A MACHINE-LEARNING TOOL Thia St Co. HARRIS, CHRISTOPHER C 2432 §101§103§112 Non-Final OA — Pending Mar 24, 2025
19113166 LIGHT-SHIELDING HARD CAPSULE CONTAINING MAGNESIUM OXIDE Capsugel Belgium NV SAEED, ALI S 1616 §103§112 Non-Final OA — Pending Mar 19, 2025
19073634 APPARATUS AND METHODS FOR SHIP PROPELLER SHAFT REMOVAL Vigor Industrial LLC CIGNA, JACOB JAMES 3726 §103 Non-Final OA — Pending Mar 07, 2025
19109417 SEQUENCE GENERATOR Vitalthings Uwb AS WELLS, KENNETH B 2836 §112 Non-Final OA — Pending Mar 06, 2025
19067898 Context-Dependent Generation of Supplemental Information on a Per-Level Basis in a Neural Network Microsoft Technology Licensing, LLC DUGDA, MULUGETA TUJI 2653 §101§102§103 Non-Final OA — Pending Mar 01, 2025
19067886 Speculative Decoding using Expanded Token Matching Microsoft Technology Licensing, LLC LEE, JANGWOEN 2656 §103 Non-Final OA — Pending Mar 01, 2025
19066796 ROTATABLE PRINTHEAD FOR ELECTROHYDRODYNAMIC PROCESSES University of Oregon LIANG, SHIBIN 1741 §102§103 Non-Final OA — Pending Feb 28, 2025
19107013 AQUEOUS HUMOR OUTFLOW DEVICE INSERTION APPARATUS FOR INSERTING AQUEOUS HUMOR OUTFLOW DEVICE FOR GLAUCOMA TREATMENT INTO EYE Seoul National University Hospital MILLER, SERENITY A 3771 §101§102§103 Non-Final OA — Pending Feb 26, 2025
19106991 SCIENTIFIC INSTRUMENT SUPPORT SYSTEMS AND METHODS FOR MITIGATING SPECTRAL DRIFT Thermo Fisher Scientific (Bremen) GmbH PEREZ-GUZMAN, CARLOS GABRIEL 2877 §102§103 Non-Final OA — Pending Feb 26, 2025
19057833 FOUR-LAYERED MATERIAL FOR A FLEXIBLE FLUID RESERVOIR Tsi Manufacturing, LLC CHEYNEY, CHARLES 3754 §103 Non-Final OA — Pending Feb 19, 2025
19037591 NEURAL NETWORK MARGIN PROPOSAL James R. Glidewell Dental Ceramics, Inc. BAKER, CHARLOTTE M §103§112Other Non-Final OA — Pending Jan 27, 2025
19034136 COMPUTER-IMPLEMENTED AUTHENTICATION PLATFORM Banqu, Inc. TSANG, HENRY 2495 §102§103Other Non-Final OA — Pending Jan 22, 2025
19014433 FOOTWEAR STROBEL INCLUDING A SHANK, AN ARTICLE OF FOOTWEAR, AND A METHOD OF MANUFACTURING AN ARTICLE OF FOOTWEAR Nike, Inc. FERREIRA, CATHERINE M 3732 §102§103 Non-Final OA — Pending Jan 09, 2025
18992165 SYSTEMS AND METHODS OF 3D VOLUMETRIC ULTRASOUND IMAGING UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION VIRK, ADIL PARTAP S 3798 §103§112 Non-Final OA 14d Pending Jan 07, 2025
19008298 SUPPORT GARMENT Nike, Inc. TAUFIQ, FARAH N 1754 §103§112 Final Rejection — Pending Jan 02, 2025
19005395 VIBRATION CONTROL OF STRUCTURAL ELEMENTS OF EXPOSURE APPARATUS Nikon Corporation RIDDLE, CHRISTINA A 2882 §103§112 Non-Final OA — Pending Dec 30, 2024
18878637 MAXILLO-MANDIBULAR MEASUREMENT TOOL UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION APONTE, MIRAYDA ARLENE 3772 §102 Non-Final OA — Pending Dec 23, 2024
18719795 MACROCYCLIC PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISEASE CONTAINING SAME AS ACTIVE INGREDIENT Whan In Pharmaceutical Co., Ltd. KIFLE, BRUCK 1624 §102§103§112 Non-Final OA — Pending Dec 20, 2024
18877235 SENSOR HOLDING DEVICE Sartorius Stedim Biotech GmbH RAEVIS, ROBERT R 2855 §102§103§112 Non-Final OA — Pending Dec 19, 2024
18985677 COMPRESSION OF CT RECONSTRUCTION IMAGES James R. Glidewell Dental Ceramics, Inc. LE, MICHAEL 2614 §112DP Non-Final OA — Pending Dec 18, 2024
18975483 DATA-DRIVEN STRUCTURE EXTRACTION FROM TEXT DOCUMENTS SAP SE WONG, LINDA 2655 §103 Non-Final OA — Pending Dec 10, 2024
18872484 LUNG FUNCTION TESTING Eupnoos Ltd. HOEKSTRA, JEFFREY GERBEN 3791 §101§102§112 Non-Final OA — Pending Dec 06, 2024
18970684 COMBINED CHANGE-POINT ANALYZER FOR DATABASE SYSTEMS SAP SE ADAMS, CHARLES D 2165 §101§103 Non-Final OA — Pending Dec 05, 2024
18870588 DATA DRIVEN ADOPTIVE CONTROL OF CHROMATOGRAPHY SYSTEMS Sartorius Stedim Data Analytics AB KHATIB, RAMI 3669 §101§102§103§112 Non-Final OA — Pending Nov 29, 2024
18955676 TRANSMISSION ELECTRON MICROSCOPE WITH VARIABLE EFFECTIVE FOCAL LENGTH Fei Company CHOI, JAMES J 2878 §103§112 Non-Final OA — Pending Nov 21, 2024
18954772 IRON MAN (IMA) OVEREXPRESSION INCREASES DISEASE RESISTANCE Salk Institute For Biological Studies MEYER, GEORGE WILLIAM 1662 §103§112 Non-Final OA — Pending Nov 21, 2024
18952892 Dynamic Feature Management and Version Control in Distributed Software Applications SAP SE DO, CHAT C 2193 §101§102§103 Non-Final OA — Pending Nov 19, 2024
18949779 SYSTEM AND METHOD FOR EFFICIENTLY IMPORTING GEOSPATIAL DATA INTO THE H3 INDEXING SYSTEM Southern Oregon University SHECHTMAN, CHERYL MARIA 2164 §101§102§103§112 Final Rejection — Pending Nov 15, 2024
18866040 AUTOFLOWERING GENES Phylos Bioscience, Inc. WILLIAMS, KEITH RICHARD 1663 §101§102 Non-Final OA — Pending Nov 14, 2024
18942823 Selecting and Placing Objects in Images Microsoft Technology Licensing, LLC MAHROUKA, WASSIM 2665 §103 Non-Final OA — Pending Nov 11, 2024
18942315 METHOD FOR PRESSURE EQUALISATION OF SIMULTANEOUSLY OPERATED COLUMNS Dionex Softron GmbH RAEVIS, ROBERT R §103§112 Non-Final OA — Pending Nov 08, 2024
18864483 RADIO ROUTING Nordic Semiconductor ASA ZHANG, ZHENSHENG §103 Non-Final OA — Pending Nov 08, 2024
18935969 SHIPPING MAILER WITH CORRUGATED MATERIAL HAVING ADHERED AND NON-ADHERED ZONES Packaging Corporation Of America HELVEY, PETER N. 3734 §103Other Non-Final OA — Pending Nov 04, 2024

View all 368 →

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Frequently Asked Questions

What is Klarquist Sparkman, LLP's patent allowance rate?

86.6% of resolved applications prosecuted by Klarquist Sparkman, LLP were allowed, across 18,129 applications in USPTO records.

How many office actions does Klarquist Sparkman, LLP average before allowance?

3.11 office actions per allowed application on average.

How many pending office actions does Klarquist Sparkman, LLP have?

368 pending office actions as of October 2026, for 130 clients, before 330 examiners in 189 art units.

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