Prosecution Insights
Last updated: October 04, 2026

Biospark Intellectual Property Law

Technology area: Biotechnology & Pharmaceuticals

29 pending office actions • 14 clients • 25 examiners • 14 art units • 0 of 29 (0%) have an AI response strategy ready • 15 patents granted in the last 365 days

Analysis

Biospark Intellectual Property Law specializes in Biotechnology & Pharmaceuticals, where it has handled 578 career applications. The firm has a resolved allowance rate of 70.49 percent, which provides a baseline for its success in this complex field. Currently, the firm is managing 18 pending office actions relative to its 578 career applications.

The firm's prosecution process is characterized by an average of 3.44 office actions per allowance. This 3.44 average suggests a thorough and sometimes lengthy negotiation process with the patent office. For practitioners, the 578 career applications and the 70.49 percent resolved allowance rate offer a clear view of the firm's performance. The 18 pending office actions and the 3.44 office actions per allowance metric further illustrate the firm's active workload and its typical path to achieving an allowance. These data points together provide a detailed look at the firm's prosecution history and its effectiveness.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Quality Metrics (n=578 apps, methodology: how we score firms)

70.5%
Allowance Rate
n=578
+0.66σ
Allowance Rate (norm)
n=578
3.4
OAs to Allowance
n=172
-0.20σ
OAs to Allow (norm)
n=172
992 days
Time to Allowance
n=172
+33.1pp
Interview Lift
n=578
26.2%
RCE Rate
n=578
1.5%
Appeal Rate
n=578

Rejection Performance (% of received rejections ultimately overcome)

74.1%
§101 Overcome
n=27
70.3%
§102 Overcome
n=101
58.9%
§103 Overcome
n=129
66.3%
§112 Overcome
n=172

Specialization & Scale

A61K, A61P, C07K
Top CPC Subclasses
64%
Top-3 CPC Share
n=578
4
Practitioners
n=578
144.5
Apps / Practitioner
n=578

Portfolio Summary

29
Total Pending OAs
20
Non-Final OAs
8
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 5 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

3
Overdue
0
Due this week
1
Due this month
1
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 5 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (3)Due ≤ 30 days (1)Due ≤ 60 days (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

13
Hard (45%)
10
Medium (34%)
6
Easy (21%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other2 (7%)
§103 only4 (14%)
§102 only1 (3%)
§112 only4 (14%)
Double-patenting only2 (7%)
Double-patenting + other5 (17%)
Multi-statute (no §101)11 (38%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

22
Life Sciences
76% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
7
Business / Other
24% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

290 h
Manual time on pending OAs
58 h
Time saved (low, 20%)
102 h
Time saved (mid, 35%)
2.5 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
SALVOZA, M FRANCO G 2 68.4% +30.0%
LU, CHENG 2 54.1% +64.1%
DONOGHUE, BRITTNEY ERIN 2 58.8% +46.5%
STONEBRAKER, ALYSSA RAE 2 58.3% +49.2%
MONTANARI, DAVID A 1 64.7% +49.0%
NOTTINGHAM, KYLE GREGORY 1 61.7% +31.9%
SEAMAN, D MARGARET M 1 76.5% +8.0%
ARNOLD, ERNST V 1 48.2% +12.9%
GULLEDGE, BRIAN M 1 55.8% +26.1%
RAHMANI, NILOOFAR 1 77.5% -2.9%

Hard Cases (13)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17613898 GLUCONATE DEHYDRATASE ENZYMES AND RECOMBINANT CELLS IANNUZO, NATALIE NMN 24d overdue
17055511 BACTERIAL VECTORS FOR GENETIC MANIPULATION OF BACTERIA LIPPOLIS, ALEXANDRA ROSE 12d
18700024 NANOPARTICULATE FORMULATION ARNOLD, ERNST V 46d
18615334 METHODS AND COMPOUNDS FOR THE TREATMENT OR PREVENTION OF HYPERCYTOKINEMIA AND SEVERE INFLUENZA RAHMANI, NILOOFAR —
18417702 TREATMENT OF COMPLEMENT-MEDIATED DISORDERS LEONARD, ARTHUR S —
18576878 MELFLUFEN FOR USE IN THE TREATMENT OF MULTIPLE MYELOMA JAUHARI, SACHI —
18571367 CAPSID VARIANTS AND METHODS OF USING THE SAME CORNELIUS, CLAIRE ADRIENNE —
18324380 INTERLEUKIN-2 PROPROTEINS AND USES THEREOF DONOGHUE, BRITTNEY ERIN —

Interview Candidates (12)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17887565 IL27 RECEPTOR AGONISTS AND METHODS OF USE THEREOF DONOGHUE, BRITTNEY ERIN 15d overdue
18700024 NANOPARTICULATE FORMULATION ARNOLD, ERNST V 46d
19537081 CAPSID POLYPEPTIDES AND METHODS OF USE THEREOF MONTANARI, DAVID A —
18917773 COMPOUNDS CONTAINING DEUTERIUM NOTTINGHAM, KYLE GREGORY —
18779855 CAPSID VARIANTS AND METHODS OF USING THE SAME SALVOZA, M FRANCO G —
18761730 CAPSID VARIANTS AND METHODS OF USING THE SAME SALVOZA, M FRANCO G —
18670314 STEROIDS AND ANTIBODY-CONJUGATES THEREOF LU, CHENG —
18700066 NANOPARTICULATE FORMULATION GULLEDGE, BRIAN M —

Client Portfolio (14 clients)

Top Art Units

Art UnitApps
16425
16443
16722
16752
16321
16131
16991
16911
16311
16541

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
19537081 CAPSID POLYPEPTIDES AND METHODS OF USE THEREOF Dyno Therapeutics, Inc. MONTANARI, DAVID A 1632 §112 Final Rejection — Pending Feb 11, 2026
18917773 COMPOUNDS CONTAINING DEUTERIUM Oncopeptides Innovation AB NOTTINGHAM, KYLE GREGORY §112DP Non-Final OA — Pending Oct 16, 2024
18779855 CAPSID VARIANTS AND METHODS OF USING THE SAME Dyno Therapeutics, Inc. SALVOZA, M FRANCO G DP Non-Final OA — Pending Jul 22, 2024
18400055 LYOPHILIZED PREPARATION OF CYTOTOXIC DIPEPTIDES Oncopeptides AB SEAMAN, D MARGARET M §103 Non-Final OA — Pending Jul 19, 2024
18761730 CAPSID VARIANTS AND METHODS OF USING THE SAME Dyno Therapeutics, Inc. SALVOZA, M FRANCO G DP Non-Final OA — Pending Jul 02, 2024
18670314 STEROIDS AND ANTIBODY-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. LU, CHENG 1642 §103DP Non-Final OA — Pending May 21, 2024
18700024 NANOPARTICULATE FORMULATION Newimmune Ii, LLC ARNOLD, ERNST V 1613 §103§112Other Final Rejection 46d Pending Apr 10, 2024
18700066 NANOPARTICULATE FORMULATION Newimmune Ii, LLC GULLEDGE, BRIAN M 1699 §103 Final Rejection — Pending Apr 10, 2024
18615334 METHODS AND COMPOUNDS FOR THE TREATMENT OR PREVENTION OF HYPERCYTOKINEMIA AND SEVERE INFLUENZA Poolbeg Pharma (Uk) Limited RAHMANI, NILOOFAR 1691 §102§112 Non-Final OA — Pending Mar 25, 2024
18589384 MULTIVALENT ANTI-SPIKE PROTEIN BINDING MOLECULES AND USES THEREOF Regeneron Pharmaceuticals, Inc. METCALF, MATTHEW CURRAN §102§103DP Non-Final OA — Pending Feb 27, 2024
18417702 TREATMENT OF COMPLEMENT-MEDIATED DISORDERS The Sydney Children's Hospitals Network LEONARD, ARTHUR S 1631 §102§103 Non-Final OA — Pending Jan 19, 2024
18580810 IL12 RECEPTOR AGONISTS AND METHODS OF USE THEREOF Regeneron Pharmaceuticals, Inc. ALLEN, MARIANNE P §112 Non-Final OA — Pending Jan 19, 2024
18576878 MELFLUFEN FOR USE IN THE TREATMENT OF MULTIPLE MYELOMA Oncopeptides Innovation AB JAUHARI, SACHI §102§103§112Other Non-Final OA — Pending Jan 05, 2024
18573582 CAPSID VARIANTS AND METHODS OF USING THE SAME Dyno Therapeutics, Inc. CHESTNUT, BARRY A 1672 §102 Non-Final OA — Pending Dec 22, 2023
18571367 CAPSID VARIANTS AND METHODS OF USING THE SAME Dyno Therapeutics, Inc. CORNELIUS, CLAIRE ADRIENNE 1672 §101§112 Final Rejection — Pending Dec 18, 2023
18548772 ANTI-GLYCO-CD44 ANTIBODIES AND THEIR USES Go Therapeutics, Inc. LU, CHENG 1642 §112DP Non-Final OA — Pending Sep 01, 2023
18324380 INTERLEUKIN-2 PROPROTEINS AND USES THEREOF Regeneron Pharmaceuticals, Inc. DONOGHUE, BRITTNEY ERIN 1675 §103§112 Non-Final OA — Pending May 26, 2023
18133288 COMPOSITIONS AND METHODS FOR UNIVERSAL TUMOR CELL KILLING Regeneron Pharmaceuticals, Inc. STONEBRAKER, ALYSSA RAE 1642 §103§112 Non-Final OA — Pending Apr 11, 2023
18247465 METHODS FOR TREATING EYE DISEASES USING LIPID BINDING PROTEIN-BASED COMPLEXES Abionyx Pharma SA AUDET, MAURY A 1654 §103 Final Rejection — Pending Mar 31, 2023
18003279 IMMUNOTHERAPY Neogap Therapeutics AB JUEDES, AMY E 1644 §103DP Final Rejection — Pending Dec 23, 2022
17928803 NUCLEIC ACID ENCODING AN ANTI-VEGF ENTITY AND A NEGATIVE COMPLEMENT REGULATOR AND USES THEREOF FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION Gyroscope Therapeutics Limited XIAO, YAN 1642 §102§103§112 Non-Final OA — Pending Nov 30, 2022
17928798 METHODS OF PRODUCING RECOMBINANT COMPLEMENT PROTEINS, VECTORS AND THERAPEUTIC USES THEREOF Novartis Pharmaceuticals UK Limited LOUNTOS, GEORGE THEMISTOCLIS 1652 §103§112 Non-Final OA — Pending Nov 30, 2022
17909045 ANTI-GLYCO-CD44 ANTIBODIES AND THEIR USES Go Therapeutics, Inc. GEORGE, DENNIS CHERIAN 1644 §101§103§112DP Non-Final OA — Pending Sep 02, 2022
17887565 IL27 RECEPTOR AGONISTS AND METHODS OF USE THEREOF Regeneron Pharmaceuticals, Inc. DONOGHUE, BRITTNEY ERIN 1675 §103 Non-Final OA 15d overdue Pending Aug 15, 2022
17735510 MULTISPECIFIC FGF21 RECEPTOR AGONISTS AND THEIR USES Regeneron Pharmaceuticals, Inc. SAOUD, CHRISTINE J 1600 §112 Non-Final OA — Pending May 03, 2022
17613898 GLUCONATE DEHYDRATASE ENZYMES AND RECOMBINANT CELLS BP CORPORATION NORTH AMERICA INC. IANNUZO, NATALIE NMN 1653 §103§112 Final Rejection 24d overdue Pending Nov 23, 2021
17612204 TRACELESS LINKERS AND PROTEIN-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. STONEBRAKER, ALYSSA RAE 1642 §103§112 Non-Final OA — Pending Nov 17, 2021
17417601 PHAGOCYTISABLE PARTICLE FOR USE IN THE TREATMENT OR PROPHYLAXIS OF CANCER Neogap Therapeutics AB JOHANSEN, PETER N. 1644 §112 Non-Final OA 17d overdue Pending Jun 23, 2021
17055511 BACTERIAL VECTORS FOR GENETIC MANIPULATION OF BACTERIA BIOVERSYS AG LIPPOLIS, ALEXANDRA ROSE 1637 §103§112 Final Rejection 12d Pending Nov 13, 2020

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