Prosecution Insights
Last updated: August 06, 2026

Biospark Intellectual Property Law

16 pending office actions • 12 clients • 16 examiners • 12 art units • 0 of 16 (0%) have an AI response strategy ready • 18 patents granted in the last 365 days

Quality Metrics (n=567 apps, methodology: how we score firms)

70.5%
Allowance Rate
n=567
+0.65σ
Allowance Rate (norm)
n=567
3.4
OAs to Allowance
n=167
-0.20σ
OAs to Allow (norm)
n=167
985 days
Time to Allowance
n=167
+32.9pp
Interview Lift
n=567
26.2%
RCE Rate
n=567
1.6%
Appeal Rate
n=567

Rejection Performance (% of received rejections ultimately overcome)

80.0%
§101 Overcome
n=25
73.2%
§102 Overcome
n=97
61.9%
§103 Overcome
n=118
69.4%
§112 Overcome
n=160

Specialization & Scale

A61K, A61P, C07K
Top CPC Subclasses
63%
Top-3 CPC Share
n=567
4
Practitioners
n=567
141.8
Apps / Practitioner
n=567

Portfolio Summary

16
Total Pending OAs
9
Non-Final OAs
7
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 5 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

5
Overdue
0
Due this week
0
Due this month
0
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 5 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (5)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

6
Hard (38%)
8
Medium (50%)
2
Easy (12%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§103 only5 (31%)
§102 only1 (6%)
§112 only2 (12%)
Double-patenting + other2 (12%)
Multi-statute (no §101)6 (38%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

15
Life Sciences
94% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
1
Business / Other
6% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

160 h
Manual time on pending OAs
32 h
Time saved (low, 20%)
56 h
Time saved (mid, 35%)
1.4 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
GULLEDGE, BRIAN M 1 55.6% +26.3%
RAHMANI, NILOOFAR 1 77.5% -3.1%
ALLEN, MARIANNE P 1 60.1% +18.3%
CHESTNUT, BARRY A 1 73.4% +6.3%
MERTZ, PREMA MARIA 1 71.6% +35.6%
DONOGHUE, BRITTNEY ERIN 1 58.6% +48.8%
HIRAKIS, SOPHIA P 1 52.2% +73.3%
AUDET, MAURY A 1 50.0% +23.8%
JUEDES, AMY E 1 45.0% +41.4%
ESPINOSA, CLAUDIA EDILMA 1 52.9% +56.1%

Hard Cases (6)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 6 ordered by deadline are shown.

App #TitleExaminerDue in
17978647 ANTIBIOTIC COMBINATION THERAPIES ESPINOSA, CLAUDIA EDILMA 31d overdue
17613898 GLUCONATE DEHYDRATASE ENZYMES AND RECOMBINANT CELLS IANNUZO, NATALIE NMN 24d overdue
17620987 DOSING REGIMEN AND COMBINATION THERAPIES FOR MULTISPECIFIC ANTIBODIES TARGETING B-CELL MATURATION ANTIGEN NICKOL, GARY B 15d overdue
18615334 METHODS AND COMPOUNDS FOR THE TREATMENT OR PREVENTION OF HYPERCYTOKINEMIA AND SEVERE INFLUENZA RAHMANI, NILOOFAR
18251443 METHODS FOR TREATMENT OF CANCER AND PHAGOCYTOSIS-DEFICIENCY RELATED DISEASES HIRAKIS, SOPHIA P
17612204 TRACELESS LINKERS AND PROTEIN-CONJUGATES THEREOF STONEBRAKER, ALYSSA RAE

Interview Candidates (8)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17978647 ANTIBIOTIC COMBINATION THERAPIES ESPINOSA, CLAUDIA EDILMA 31d overdue
18700066 NANOPARTICULATE FORMULATION GULLEDGE, BRIAN M
18580810 IL12 RECEPTOR AGONISTS AND METHODS OF USE THEREOF ALLEN, MARIANNE P
18328327 INTERLEUKIN-2 PROPROTEINS AND USES THEREOF MERTZ, PREMA MARIA
18324380 INTERLEUKIN-2 PROPROTEINS AND USES THEREOF DONOGHUE, BRITTNEY ERIN
18251443 METHODS FOR TREATMENT OF CANCER AND PHAGOCYTOSIS-DEFICIENCY RELATED DISEASES HIRAKIS, SOPHIA P
18247465 METHODS FOR TREATING EYE DISEASES USING LIPID BINDING PROTEIN-BASED COMPLEXES AUDET, MAURY A
18003279 IMMUNOTHERAPY JUEDES, AMY E

Client Portfolio (12 clients)

Top Art Units

Art UnitApps
16542
16442
16422
16991
16911
16721
16741
16751
16231
16431

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
18700066 NANOPARTICULATE FORMULATION Newimmune Ii, LLC GULLEDGE, BRIAN M 1699 §103 Final Rejection Pending Apr 10, 2024
18615334 METHODS AND COMPOUNDS FOR THE TREATMENT OR PREVENTION OF HYPERCYTOKINEMIA AND SEVERE INFLUENZA Poolbeg Pharma (Uk) Limited RAHMANI, NILOOFAR 1691 §102§112 Non-Final OA Pending Mar 25, 2024
18580810 IL12 RECEPTOR AGONISTS AND METHODS OF USE THEREOF Regeneron Pharmaceuticals, Inc. ALLEN, MARIANNE P §112 Non-Final OA Pending Jan 19, 2024
18573582 CAPSID VARIANTS AND METHODS OF USING THE SAME Dyno Therapeutics, Inc. CHESTNUT, BARRY A 1672 §102 Non-Final OA Pending Dec 22, 2023
18328327 INTERLEUKIN-2 PROPROTEINS AND USES THEREOF Regeneron Pharmaceuticals, Inc. MERTZ, PREMA MARIA 1674 §112 Non-Final OA Pending Jun 02, 2023
18324380 INTERLEUKIN-2 PROPROTEINS AND USES THEREOF Regeneron Pharmaceuticals, Inc. DONOGHUE, BRITTNEY ERIN 1675 §103 Non-Final OA Pending May 26, 2023
18251443 METHODS FOR TREATMENT OF CANCER AND PHAGOCYTOSIS-DEFICIENCY RELATED DISEASES Rdiscovery, LLC HIRAKIS, SOPHIA P 1623 §103§112 Non-Final OA Pending May 02, 2023
18247465 METHODS FOR TREATING EYE DISEASES USING LIPID BINDING PROTEIN-BASED COMPLEXES Abionyx Pharma SA AUDET, MAURY A 1654 §103 Final Rejection Pending Mar 31, 2023
18003279 IMMUNOTHERAPY Neogap Therapeutics AB JUEDES, AMY E 1644 §103DP Final Rejection Pending Dec 23, 2022
17978647 ANTIBIOTIC COMBINATION THERAPIES BIOVERSYS AG ESPINOSA, CLAUDIA EDILMA 1654 §103§112Other Final Rejection 31d overdue Pending Nov 01, 2022
17620987 DOSING REGIMEN AND COMBINATION THERAPIES FOR MULTISPECIFIC ANTIBODIES TARGETING B-CELL MATURATION ANTIGEN Novartis AG NICKOL, GARY B 1643 §102§112Other Non-Final OA 15d overdue Pending Dec 20, 2021
17620222 ANTIBODY-ALK5 INHIBITOR CONJUGATES AND THEIR USES Synthis Therapeutics, Inc. BUTTICE, AUDREY L 1647 §103DP Non-Final OA Pending Dec 17, 2021
17616246 BREAST CANCER DETECTION METHODS Cambridge Enterprise Limited SULLIVAN, DENNIS JOHN 1642 §103 Non-Final OA 5d overdue Pending Dec 03, 2021
17613898 GLUCONATE DEHYDRATASE ENZYMES AND RECOMBINANT CELLS BP CORPORATION NORTH AMERICA INC. IANNUZO, NATALIE NMN 1653 §103§112 Final Rejection 24d overdue Pending Nov 23, 2021
17612204 TRACELESS LINKERS AND PROTEIN-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. STONEBRAKER, ALYSSA RAE 1642 §103§112 Final Rejection Pending Nov 17, 2021
17417601 PHAGOCYTISABLE PARTICLE FOR USE IN THE TREATMENT OR PROPHYLAXIS OF CANCER Neogap Therapeutics AB JOHANSEN, PETER N. 1644 §103Other Final Rejection 17d overdue Pending Jun 23, 2021

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