Prosecution Insights
Last updated: October 04, 2026

Arrigo, Lee, Guttman & Mouta-Bellum LLP

Technology area: Biotechnology & Pharmaceuticals

51 pending office actions • 34 clients • 46 examiners • 30 art units • 0 of 51 (0%) have an AI response strategy ready

Analysis

ARRIGO, LEE, GUTTMAN & MOUTA-BELLUM LLP focuses on the Biotechnology & Pharmaceuticals technology area. The firm has processed 1313 career applications, resulting in a resolved allowance rate pct of 83.02. This indicates a track record in securing allowances for complex life sciences inventions. The 83.02 percent allowance rate is a key indicator of the firm's results in securing patent rights. Practitioners can use this data to evaluate the firm's historical performance across its career filings.

Currently, the firm has 48 pending office actions. The average of 4.19 office actions per allowance serves as a measure of the typical prosecution duration and effort. This 4.19 average helps in setting expectations for the number of interactions required to reach a final decision. With 1313 applications in its history, the firm has a documented record of performance. The 48 pending office actions represent the current volume of active matters the firm is pursuing.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Quality Metrics (n=1313 apps, methodology: how we score firms)

83.0%
Allowance Rate
n=1313
+0.95σ
Allowance Rate (norm)
n=1313
4.2
OAs to Allowance
n=797
-0.03σ
OAs to Allow (norm)
n=797
1120 days
Time to Allowance
n=797
+23.3pp
Interview Lift
n=1313
29.3%
RCE Rate
n=1313
1.8%
Appeal Rate
n=1313

Rejection Performance (% of received rejections ultimately overcome)

78.6%
§101 Overcome
n=145
73.9%
§102 Overcome
n=337
75.1%
§103 Overcome
n=598
79.2%
§112 Overcome
n=701

Specialization & Scale

A61K, C12N, A61P
Top CPC Subclasses
51%
Top-3 CPC Share
n=1313
4
Practitioners
n=1313
328.2
Apps / Practitioner
n=1313

Portfolio Summary

51
Total Pending OAs
29
Non-Final OAs
22
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 17 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

12
Overdue
0
Due this week
2
Due this month
1
Due in next 60 days
2
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 17 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (12)Due ≤ 30 days (2)Due ≤ 60 days (1)Due later (2)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

25
Hard (49%)
18
Medium (35%)
8
Easy (16%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other4 (8%)
§103 only9 (18%)
§102 only2 (4%)
§112 only8 (16%)
Double-patenting + other7 (14%)
Multi-statute (no §101)21 (41%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

36
Life Sciences
71% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
5
Mechanical / Eng
10% of docket
10
Business / Other
20% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

510 h
Manual time on pending OAs
102 h
Time saved (low, 20%)
178 h
Time saved (mid, 35%)
4.5 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
KIM, TAEYOON 3 51.5% +52.1%
NOLAN, JASON MICHAEL 2 66.5% -27.8%
BLUMEL, BENJAMIN P 2 70.8% +30.5%
KATAKAM, SUDHAKAR 2 74.7% +23.3%
ZHU, JIANJIAN 1 58.8% +82.4%
MOAZZAMI, NAGHMEH NINA 1 72.0% +49.3%
MARCSISIN, ELLEN JEAN 1 34.5% +49.3%
WEHBE, ANNE MARIE SABRINA 1 57.2% +43.4%
SCHMITT, BENJAMIN ALLYN 1 8.3% +40.0%
BLEDSOE, JOSHUA CALEB 1 44.4% +52.7%

Hard Cases (25)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18259979 DRUG ELUTING STENT LYNCH, ROBERT A 71d overdue
18692995 METHODS FOR PREPARING PEROVSKITE SOLAR CELLS (PSCS) AND THE RESULTING PSCS KANG, TAE-SIK 38d overdue
18264079 NOVEL PROCESS NOLAN, JASON MICHAEL 30d overdue
17422737 AAV-MEDIATED GENE THERAPY RESTORING THE OTOFERLIN GENE KIM, TAEYOON 15d overdue
18262523 DETECTING BETA-LACTAMASE ENZYME ACTIVITY REGLAS, GEORGIANA C 5d overdue
17997439 POROUS BONE SUBSTITUTION MATERIAL BLANCO, JAVIER G 4d overdue
17641787 ANTI-NUCLEOLIN AGENT-PEG-CONJUGATED NANOPARTICLES MEJIAS, SAMANTHA LEE 3d overdue
17862892 3-D BIOPRINTING COMPRISING BIOLOGICALLY-RELEVANT MATERIALS AND RELATED METHODS KIM, TAEYOON 12d

Interview Candidates (13)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17422737 AAV-MEDIATED GENE THERAPY RESTORING THE OTOFERLIN GENE KIM, TAEYOON 15d overdue
17862892 3-D BIOPRINTING COMPRISING BIOLOGICALLY-RELEVANT MATERIALS AND RELATED METHODS KIM, TAEYOON 12d
18981938 PHYSIOLOGICAL BIOMIMETIC CULTURE SYSTEM FOR HEART SLICES ZHU, JIANJIAN —
18914680 CELLULAR IMMUNOTHERAPY FOR REPETITIVE ADMINISTRATION KIM, TAEYOON —
18849851 BIOSYNTHESIS MOAZZAMI, NAGHMEH NINA —
18728027 METHOD FOR DETECTING A TAU PROTEIN IN A SALIVA SAMPLE MARCSISIN, ELLEN JEAN —
18744060 Use of a Vaccine Targeting a Cryptic Tert Epitope, for Treating Cancer in a HLA-A*0201-Positive Patient Having a Non-Immunogenic Tumor Expressing Tert WEHBE, ANNE MARIE SABRINA —
18714448 ARM-WORN ELECTROCARDIOGRAPHIC DEVICE AND METHOD FOR ELECTROCARDIOGRAPHIC SIGNAL MEASUREMENT SCHMITT, BENJAMIN ALLYN —

Client Portfolio (34 clients)

Top Art Units

Art UnitApps
16314
16413
16232
16722
37712
16822
16372
16562
16182
37961

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
18981938 PHYSIOLOGICAL BIOMIMETIC CULTURE SYSTEM FOR HEART SLICES UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. ZHU, JIANJIAN §103 Non-Final OA — Pending Dec 16, 2024
18914680 CELLULAR IMMUNOTHERAPY FOR REPETITIVE ADMINISTRATION Cellectis KIM, TAEYOON §103§112DP Non-Final OA — Pending Oct 14, 2024
18849851 BIOSYNTHESIS Plant Bioscience Limited MOAZZAMI, NAGHMEH NINA §112Other Non-Final OA — Pending Sep 23, 2024
18728027 METHOD FOR DETECTING A TAU PROTEIN IN A SALIVA SAMPLE Gtinvent Limited MARCSISIN, ELLEN JEAN §103§112DP Non-Final OA — Pending Jul 10, 2024
18744060 Use of a Vaccine Targeting a Cryptic Tert Epitope, for Treating Cancer in a HLA-A*0201-Positive Patient Having a Non-Immunogenic Tumor Expressing Tert Kriptic Pharmaceuticals Limited WEHBE, ANNE MARIE SABRINA §102§103DP Non-Final OA — Pending Jun 14, 2024
18714448 ARM-WORN ELECTROCARDIOGRAPHIC DEVICE AND METHOD FOR ELECTROCARDIOGRAPHIC SIGNAL MEASUREMENT Demedar Spolka Z Ograniczona Odpowiedzialnoscia SCHMITT, BENJAMIN ALLYN 3796 §103§112 Non-Final OA — Pending May 29, 2024
18701664 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER Artios Pharma Limited NOLAN, JASON MICHAEL 1623 §112 Non-Final OA — Pending Apr 16, 2024
18613613 Silk Packaging Applications Cambridge Crops, Inc,.D.B.A./Mori BLEDSOE, JOSHUA CALEB 1762 §103§112Other Non-Final OA — Pending Mar 22, 2024
18692995 METHODS FOR PREPARING PEROVSKITE SOLAR CELLS (PSCS) AND THE RESULTING PSCS Alliance for Energy Innovation, LLC KANG, TAE-SIK 1728 §102§112 Non-Final OA 38d overdue Pending Mar 18, 2024
18598495 BACTERIAL DELIVERY VEHICLE, PROCESS OF PRODUCTION AND USES THEREOF Eligo Bioscience KINSEY WHITE, NICOLE ERIN 1672 §112 Final Rejection — Pending Mar 07, 2024
18582939 OPTIMIZED VECTOR FOR DELIVERY IN MICROBIAL POPULATIONS Institut Pasteur BLUMEL, BENJAMIN P §102§103§112 Non-Final OA — Pending Feb 21, 2024
18424461 PRODUCTION BACTERIAL CELLS AND USE THEREOF IN PRODUCTION METHODS Eligo Bioscience WANG, RUIXUE §103§112DP Non-Final OA — Pending Jan 26, 2024
18291050 IL-10 INDUCING POLYPEPTIDES AND USES THEREOF Enterome S.A. KATAKAM, SUDHAKAR §101§112 Non-Final OA — Pending Jan 22, 2024
18571892 METHODS FOR DIAGNOSING A CANCER- OR ANTIBIOTICS-INDUCED DYSBIOSIS AND THEIR USE FOR IMPROVING CANCER TREATMENT BY IMMUNOTHERAPY INSERM BERA, HENA RAKESHKUMAR §101§103§112 Non-Final OA — Pending Dec 19, 2023
18530878 METHODS FOR ENGINEERING ALLOGENEIC AND IMMUNOSUPPRESSIVE RESISTANT T CELL FOR IMMUNOTHERAPY Cellectis NGUYEN, QUANG 1631 §102§103§112DP Non-Final OA — Pending Dec 06, 2023
18556957 NEW ANTI-MUC1 CARS AND GENE EDITED IMMUNE CELLS FOR SOLID TUMORS CANCER IMMUNOTHERAPY Cellectis S.A. WEN, SHARON X 1641 §103§112 Non-Final OA — Pending Oct 24, 2023
18551043 LEFT ATRIAL APPENDAGE CLOSURE DEVICE WITH CATHETER-BASED DELIVERY UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. KHANDKER, RAIHAN R 3771 §103 Final Rejection — Pending Sep 18, 2023
18549286 LENTIVIRAL VECTORS TARGETING ANTIGENS TO MHC-II PATHWAY AND INDUCING PROTECTIVE CD8+ AND CD4+ T-CELL IMMUNITY IN A HOST Theravectys KIM, YUNSOO 1641 §103§112DP Non-Final OA — Pending Sep 06, 2023
18547471 ANTIBODIES, FRAGMENTS OR DERIVATIVES SPECIFICALLY BINDING TO A PROTEIN ANTIGEN CAPABLE OF BINDING TO NUCLEIC ACIDS AND USES OF SAME COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES DRISCOLL, LORA E BARNHART 3991 §112 Final Rejection 25d overdue Pending Aug 22, 2023
18547256 AN ARTIFICIAL TRAP-CAGE, ITS USE AND METHOD OF PREPARING THEREOF UNIWERSYTET JAGIELLONSKI SWIFT, CANDICE LEE 1657 §112 Final Rejection 4d overdue Pending Aug 21, 2023
18450060 ULTRATHIN NANORIBBONS OF HIGHLY ANISOTROPIC LAYERED MATERIAL AND METHOD OF PRODUCTION UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. SHERMAN, ERIC SCOTT 1736 §102 Non-Final OA — Pending Aug 15, 2023
18230278 METHOD OF TREATMENT FOR HEART FAILURE USING STEM CELLS UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. SCHUBERG, LAURA J 1631 §103 Final Rejection 34d Pending Aug 04, 2023
18264079 NOVEL PROCESS Artios Pharma Limited NOLAN, JASON MICHAEL 1623 §103§112Other Non-Final OA 30d overdue Pending Aug 03, 2023
18262523 DETECTING BETA-LACTAMASE ENZYME ACTIVITY Universite Paris-Saclay REGLAS, GEORGIANA C 1651 §102§103 Final Rejection 5d overdue Pending Jul 21, 2023
18259979 DRUG ELUTING STENT Sino Medical Sciences Technology Inc. LYNCH, ROBERT A 3771 §102§112 Non-Final OA 71d overdue Pending Jun 29, 2023
18258271 BIOMARKERS SIGNATURE(S) FOR THE PREVENTION AND EARLY DETECTION OF GASTRIC CANCER Universite De Versailles Saint Quentin En Yvelines BUCHANAN, BAILEY CHEYENNE 1682 §101§103§112 Final Rejection — Pending Jun 19, 2023
17997439 POROUS BONE SUBSTITUTION MATERIAL Etat Francais Represente Par La Direction Centrale Du Service De Sante Des Armées BLANCO, JAVIER G 3774 §102§103§112 Final Rejection 4d overdue Pending Jun 09, 2023
18002229 Method for determining potency of chimeric antigen receptor expressing immune cells Cellectis S.A. HOWARD, ZACHARY C 1674 §102§112 Final Rejection 27d Pending May 23, 2023
18253977 USE OF AMINOQUINOLINE COMPOUNDS FOR HIGHER GENE INTEGRATION Cellectis SA SU-TOBON, QIWEN NMN 1636 §102§103 Non-Final OA 63d Pending May 23, 2023
18252438 PHARMACEUTICAL COMPOSITION COMPRISING A PEPTIDE AS ACTIVE INGREDIENT Intract Pharma Limited KATAKAM, SUDHAKAR 1658 §103 Non-Final OA — Pending May 10, 2023
18040945 Method for separation and/or detection and/or in vitro quantification of infectious compounds in biological material Apoh-Technologies HELLMAN, KRISTINA M 1654 §102§112 Non-Final OA — Pending Feb 07, 2023
18005284 T-CELLS EXPRESSING IMMUNE CELL ENGAGERS IN ALLOGENIC SETTINGS Cellectis S.A. NICOL, ALEXANDER W 1634 §103 Final Rejection 26d overdue Pending Jan 12, 2023
18005146 SARS-COV-2 IMMUNOGENIC COMPOSITIONS, VACCINES, AND METHODS Theravectys CHEN, STACY BROWN 1672 §102§103§112DP Non-Final OA — Pending Jan 11, 2023
17997764 BIOMIMETIC HEART TISSUE CULTURE SYSTEM UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. HENKEL, DANIELLE B 1799 §103§112 Non-Final OA — Pending Nov 02, 2022
17996733 METHODS FOR TARGETED INSERTION OF EXOGENOUS SEQUENCES IN CELLULAR GENOMES Cellectis S.A. GOMEZ RODRIGUEZ, JULIO WASHINGTON 1637 §102§103 Non-Final OA — Pending Oct 20, 2022
17907324 NEW THERAPEUTIC TARGETS WITH AN ANTI-INFLAMMATORY AND ANTI-INTERFERON EFFECT INSERM OTTON, ALICIA L 1699 §102 Final Rejection — Pending Oct 03, 2022
17862892 3-D BIOPRINTING COMPRISING BIOLOGICALLY-RELEVANT MATERIALS AND RELATED METHODS UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. KIM, TAEYOON 1631 §103§112Other Final Rejection 12d Pending Jul 12, 2022
17789749 COMPOSITION COMPRISING HYALURONIC ACID AND A POLYOL AND/OR CARBOXYMETHYL CELLULOSE Ibsa Pharma SAS CHO, DAVID H 1693 §112 Final Rejection 8d overdue Pending Jun 28, 2022
17780336 METHOD OF LYOPHILIZATION OF A CRYOGENIZED CELLULAR COMPOSITION CONTAINING DISSOLVED GAS Larena MCKNIGHT, CIARA A 1656 §103 Non-Final OA — Pending May 26, 2022
17741686 ANTI-NUCLEOLIN AGENT-CONJUGATED NANOPARTICLES UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. JONES, DAMERON LEVEST 1618 §102§112Other Final Rejection — Pending May 11, 2022
17742173 VITRO ISOLATION AND ENRICHMENT OF NUCLEIC ACIDS USING SITE-SPECIFIC NUCLEASES Depixus GRAY, JESSICA 1682 §102§103 Final Rejection 72d Pending May 11, 2022
17768002 GENETICALLY MODIFIED HUMAN STEM CELL EXPRESSING A MUTANT HUMAN CYTOCHROME P450 2B6 PROTEIN AND ITS USE THEREOF IN THE TREATMENT OF CANCER Sorbonne Universite BURKHART, MICHAEL D 1638 §112 Final Rejection — Pending Apr 11, 2022
17761767 A NOVEL COMPLEX FORMED BETWEEN THE FLAVIVIRAL NON-STRUCTURAL NS1 PROTEIN AND PLASMA LIPOPROTEINS Institut Pasteur Du Cambodge BLUMEL, BENJAMIN P 1600 §101§103§112 Non-Final OA — Pending Mar 18, 2022
17641787 ANTI-NUCLEOLIN AGENT-PEG-CONJUGATED NANOPARTICLES UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. MEJIAS, SAMANTHA LEE 1618 §102§103§112Other Final Rejection 3d overdue Pending Mar 09, 2022
17634373 METHOD FOR IN VITRO PRODUCTION OF HYALINE CARTILAGE TISSUE Vanarix SA MARTIN, PAUL C 1653 §103 Final Rejection — Pending Feb 10, 2022
17620819 ANTHRACYCLINE DERIVATIVES Almac Discovery Limited HOPKINS, SAMANTHA LAKE 1641 §103§112Other Final Rejection — Pending Dec 20, 2021
17422737 AAV-MEDIATED GENE THERAPY RESTORING THE OTOFERLIN GENE INSERM KIM, TAEYOON 1631 §102§103 Final Rejection 15d overdue Pending Jul 13, 2021
17268596 METHOD FOR CONJUGATION OF BIOMOLECULES AND NEW USE OF GOLD DONOR FOR BIOMOLECULAR COMPLEX FORMATION UNIWERSYTET JAGIELLONSKI SPANGLER, JOSEPH RANKIN 1656 §103§112Other Final Rejection — Pending Feb 16, 2021
17055061 SUBSTITUTION OF THE MESSENGER RNA CAP WITH TWO RNA SEQUENCES INTRODUCED AT THE 5-PRIME END THEREOF Messenger Biopharma VYAS, KEYUR ANILKUMAR 1637 §103 Final Rejection 81d overdue Pending Nov 12, 2020
16789572 MODULAR HARNESS FOR PATIENTS WITH POST-NEUROLOGIC INJURY UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. MILLER, CHRISTOPHER E 3785 §103 Non-Final OA — Pending Feb 13, 2020
15713347 WIDESPREAD GENE DELIVERY TO MOTOR NEURONS USING PERIPHERAL INJECTION OF AAV VECTORS Centre National De La Recherche Scientifique SINGH, ANOOP KUMAR 1632 §112 Non-Final OA — Pending Sep 22, 2017

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