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Last updated: May 29, 2026

10X Genomics, Inc.

74 pending office actions • 18 art units • 46 examiners • 0 of 74 (0%) have an AI response strategy ready • 78 patents granted in the last 365 days

Portfolio Summary

74
Total Pending OAs
53
Non-Final OAs
20
Final Rejections
1
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 72 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

45
Overdue
4
Due this week
10
Due this month
10
Due in next 60 days
3
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 72 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (45)Due ≤ 7 days (4)Due ≤ 30 days (10)Due ≤ 60 days (10)Due later (3)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

2
Hard (3%)
46
Medium (62%)
6
Easy (8%)
20
Unknown (27%)

Rejection Statute Mix

BucketCases
§101 only2 (3%)
§103 only38 (51%)
§102 only7 (9%)
§112 only6 (8%)
Double-patenting + other1 (1%)
No statute on record20 (27%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

71
Life Sciences
96% of docket
0
Information Tech
0% of docket
2
Communications
3% of docket
0
Semiconductors
0% of docket
1
Mechanical / Eng
1% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

740 h
Manual time on pending OAs
148 h
Time saved (low, 20%)
259 h
Time saved (mid, 35%)
6.5 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
SISSON, BRADLEY L 7 19.6% +21.0%
VANN-OJUEKAIYE, KENDRA RAYCHELL 4 0.0% +0.0%
BELLAH, JEFFREY LAWRENCE 3 — —
POHNERT, STEVEN C 3 12.1% +18.3%
BUNKER, AMY M 3 29.2% +46.5%
LU, FRANK WEI MIN 3 63.0% +66.3%
RAYMONDA, MATTHEW HAROLD 3 38.5% +52.8%
BORTOLI, JONATHAN 2 76.6% +38.7%
HUTSON, RICHARD G 2 65.1% +52.9%
TURPIN, ZACHARY MARK 2 0.0% +0.0%

Hard Cases (20)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18120024 CONCATEMERIC DETECTABLE PROBES AND RELATED METHODS POHNERT, STEVEN C 184d overdue
18046457 COMPOSITIONS AND METHODS FOR USE WITH FIXED SAMPLES POHNERT, STEVEN C 139d overdue
18269634 CLEAVAGE OF CAPTURE PROBES FOR SPATIAL ANALYSIS POHNERT, STEVEN C 93d overdue
17843758 METHODS TO GENERATE CIRCULARIZABLE PROBES IN SITU BUNKER, AMY M 85d overdue
17476395 SYSTEMS AND METHODS FOR BARCODE DESIGN AND DECODING BUNKER, AMY M 79d overdue
18269593 METHODS FOR ANALYTE CAPTURE DETERMINATION VANN-OJUEKAIYE, KENDRA RAYCHELL 56d overdue
17923007 SPATIAL TRANSCRIPTOMIC TRANSFER MODES VANN-OJUEKAIYE, KENDRA RAYCHELL 31d overdue
17724977 METHODS AND DEVICES FOR SPATIAL ASSESSMENT OF RNA QUALITY VANN-OJUEKAIYE, KENDRA RAYCHELL 22d overdue

Interview Candidates (23)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18120024 CONCATEMERIC DETECTABLE PROBES AND RELATED METHODS POHNERT, STEVEN C 184d overdue
17831835 METHODS FOR ENRICHING NUCLEIC ACID LIBRARIES FOR TARGET MOLECULES THAT DO NOT PRODUCE ARTEFACTUAL ANTISENSE READS RAYMONDA, MATTHEW HAROLD 147d overdue
18046457 COMPOSITIONS AND METHODS FOR USE WITH FIXED SAMPLES POHNERT, STEVEN C 139d overdue
18131159 SYSTEMS AND METHODS FOR LIQUID DEPOSITION BORTOLI, JONATHAN 111d overdue
18269634 CLEAVAGE OF CAPTURE PROBES FOR SPATIAL ANALYSIS POHNERT, STEVEN C 93d overdue
17843758 METHODS TO GENERATE CIRCULARIZABLE PROBES IN SITU BUNKER, AMY M 85d overdue
17476395 SYSTEMS AND METHODS FOR BARCODE DESIGN AND DECODING BUNKER, AMY M 79d overdue
17835796 METHODS AND SYSTEMS FOR PROCESSING POLYNUCLEOTIDES RAYMONDA, MATTHEW HAROLD 70d overdue

Top Art Units

Art UnitApps
1682 17
1683 17
1684 11
1681 7
1652 3
1797 2
1796 2
1758 2
1687 2
1685 2

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
19087021 METHODS, KITS, AND COMPOSITIONS FOR SPATIAL DETECTION OF GENETIC VARIANTS SISSON, BRADLEY L 1682 §103 Final Rejection 5d Pending Mar 21, 2025
19082018 ANALYSIS OF NUCLEIC ACID SEQUENCES PARISI, JESSICA DANIELLE 1684 Other Non-Final OA 219d overdue Pending Mar 17, 2025
19019374 METHOD OF DETECTING TARGET NUCLEIC ACID MOLECULES SISSON, BRADLEY L 1682 §112 Final Rejection 9d overdue Pending Jan 13, 2025
18940636 PROCESSES AND SYSTEMS FOR PREPARATION OF NUCLEIC ACID SEQUENCING LIBRARIES AND LIBRARIES PREPARED USING SAME GROSS, CHRISTOPHER M 1684 §103 Non-Final OA 72d overdue Pending Nov 07, 2024
18428058 SYSTEMS AND METHODS FOR PROCESSING OPTICALLY TAGGED BEADS DAUNER, JOSEPH G 1682 Other Final Rejection 52d overdue Pending Jan 31, 2024
18427317 DEVICES AND METHODS FOR GENERATING AND RECOVERING DROPLETS BORTOLI, JONATHAN 1797 §102 Non-Final OA 29d Pending Jan 30, 2024
18538539 REVERSE TRANSCRIPTASE VARIANTS FOR IMPROVED PERFORMANCE HUTSON, RICHARD G 1652 Other Non-Final OA 57d Pending Dec 13, 2023
18513046 SYSTEMS AND METHODS FOR MACHINE VISION CALIBRATION ZHAO, CHRISTINE NMN 2677 §103 Non-Final OA 2d overdue Pending Nov 17, 2023
18511481 METHODS FOR SPATIAL ANALYSIS USING ROLLING CIRCLE AMPLIFICATION AND DETECTION PROBES BENZION, GARY 1681 §102 Non-Final OA 8d overdue Pending Nov 16, 2023
18496492 METHODS, COMPOSITIONS, AND SYSTEMS FOR SPATIAL ANALYSIS OF BIOLOGICAL SAMPLES TURPIN, ZACHARY MARK 1682 Other Non-Final OA 26d Pending Oct 27, 2023
18384537 FUSION RT VARIANTS FOR IMPROVED PERFORMANCE HUTSON, RICHARD G 1652 Other Non-Final OA 34d Pending Oct 27, 2023
18478248 TARGETED SHRINKING OR EXPANSION OF BIOMOLECULES BELLAH, JEFFREY LAWRENCE 1683 §103 Non-Final OA 30d Pending Sep 29, 2023
18478392 REDUCING SPATIAL OCCUPANCY OF MOLECULES IN A SAMPLE THROUGH SAMPLE CROSSLINKING JONES, CHRISTINE MICHELLE 1682 Other Non-Final OA 73d overdue Pending Sep 29, 2023
18452127 HIGH-THROUGHPUT METHODS FOR ANALYZING AND AFFINITY-MATURING AN ANTIGEN-BINDING MOLECULE YU, DELPHINUS DOU YI 1636 §103 Non-Final OA 6d Pending Aug 18, 2023
18233606 METHODS FOR SPATIAL ANALYSIS USING RNA-TEMPLATED LIGATION MUMMERT, STEPHANIE KANE 1681 §103 Non-Final OA 84d Pending Aug 14, 2023
18365684 SYSTEMS AND METHODS FOR IMMUNOFLUORESCENCE QUANTIFICATION TURPIN, ZACHARY MARK 1682 Other Non-Final OA 13d Pending Aug 04, 2023
18362074 METHODS AND COMPOSITIONS USING SINGLE STRAND ANNEALING PROTEINS BELLAH, JEFFREY LAWRENCE 1683 §103 Non-Final OA 5d overdue Pending Jul 31, 2023
18360135 METHODS AND COMPOSITIONS FOR IN SITU ANALYSIS USING TIME-GATED DETECTION CHOUDHURY, NURA MANSURA 1683 DPOther Non-Final OA 70d Pending Jul 27, 2023
18356933 DECOY OLIGONUCLEOTIDES AND RELATED METHODS HARVEY-BUTLER, AVANDA ELEXA 1683 §103 Non-Final OA 7d Pending Jul 21, 2023
18344339 METHODS FOR DETERMINING A LOCATION OF A TARGET NUCLEIC ACID IN A BIOLOGICAL SAMPLE SISSON, BRADLEY L 1682 §101 Final Rejection 9d overdue Pending Jun 29, 2023
18342906 COMPOSITIONS AND METHODS FOR GENERATING MOLECULAR ARRAYS USING OLIGONUCLEOTIDE PRINTING AND PHOTOLITHOGRAPHY HARVEY-BUTLER, AVANDA ELEXA 1683 §103 Non-Final OA 3d overdue Pending Jun 28, 2023
18342952 COMPOSITIONS AND METHODS FOR OLIGONUCLEOTIDE INVERSION ON ARRAYS KOVACH, KARA NICOLE 1681 §103 Non-Final OA 40d Pending Jun 28, 2023
18269593 METHODS FOR ANALYTE CAPTURE DETERMINATION VANN-OJUEKAIYE, KENDRA RAYCHELL 1682 §103 Non-Final OA 56d overdue Pending Jun 26, 2023
18269634 CLEAVAGE OF CAPTURE PROBES FOR SPATIAL ANALYSIS POHNERT, STEVEN C 1683 §102 Non-Final OA 93d overdue Pending Jun 26, 2023
18213214 METHOD FOR ENZYMATIC DISSOCIATION OF HYBRIDIZED PROBES IN SITU CHOUDHURY, NURA MANSURA 1683 §103 Non-Final OA 16d overdue Pending Jun 22, 2023
18213088 METHODS, COMPOSITIONS, AND SYSTEMS FOR DETECTING EXOGENOUS NUCLEIC ACIDS PHAM, KHAI QUYNH TIEN 1684 Other Non-Final OA 24d overdue Pending Jun 22, 2023
18328200 METHODS, SYSTEMS, AND DEVICES FOR SAMPLE INTERFACE LYLE, SOPHIA YUAN 1796 §103 Non-Final OA 23d Pending Jun 02, 2023
18319864 ENGINEERED THERMOPHILIC REVERSE TRANSCRIPTASE FRONDA, CHRISTIAN L 1652 Other Non-Final OA 16d overdue Pending May 18, 2023
18313251 ANALYSIS OF ANTIGEN AND ANTIGEN RECEPTOR INTERACTIONS SISSON, BRADLEY L 1682 §102 Non-Final OA 42d Pending May 05, 2023
18301565 METHODS AND SYSTEMS FOR PROCESSING POLYNUCLEOTIDES GREENE, CAROLYN LEE 1681 §112 Final Rejection 54d Pending Apr 17, 2023
18300814 METHODS AND COMPOSITIONS FOR PROBE DETECTION AND READOUT SIGNAL GENERATION CASH, KAILEY ELIZABETH 1683 Other Final Rejection 42d Pending Apr 14, 2023
18297137 METHODS AND COMPOSITIONS FOR ANALYZING ANTIGEN BINDING MOLECULES BUNKER, AMY M 1684 §102 Non-Final OA 83d Pending Apr 07, 2023
18132298 METHODS AND COMPOSITIONS FOR LIGATION AND SAMPLE ANALYSIS LU, FRANK WEI MIN 1683 §112 Non-Final OA 5d overdue Pending Apr 07, 2023
18131159 SYSTEMS AND METHODS FOR LIQUID DEPOSITION BORTOLI, JONATHAN 1797 §103 Non-Final OA 111d overdue Pending Apr 05, 2023
18131223 BLISTER PACKS AND USES THEREOF IMPINK, MOLLIE LLEWELLYN 3799 §103 Non-Final OA 112d overdue Pending Apr 05, 2023
18044903 SAMPLE HANDLING APPARATUS AND IMAGE REGISTRATION METHODS PEARSON, AMANDA HYEONWOO 2666 §103 Final Rejection 56d overdue Pending Mar 10, 2023
18120024 CONCATEMERIC DETECTABLE PROBES AND RELATED METHODS POHNERT, STEVEN C 1683 §103 Non-Final OA 184d overdue Pending Mar 10, 2023
18177562 FLOW FOCUSING DEVICES, SYSTEMS, AND METHODS FOR HIGH THROUGHPUT DROPLET FORMATION CHIU, MAY LEUNG 1758 §102 Non-Final OA 19d overdue Pending Mar 02, 2023
18177504 DEVICES, SYSTEMS, AND METHODS FOR HIGH THROUGHPUT DROPLET FORMATION NGUYEN, HENRY H 1758 §103 Non-Final OA 4d overdue Pending Mar 02, 2023
18175885 DEVICES AND METHODS FOR FLOW CELL ASSEMBLY AND DISASSEMBLY HYUN, PAUL SANG HWA 1796 §103 Non-Final OA 26d Pending Feb 28, 2023
18023963 METHODS OF DETERMINING THE LOCATION OF AN ANALYTE IN A BIOLOGICAL SAMPLE USING A PLURALITY OF WELLS OLSON, ALEXANDRA NADINE 1684 Other Non-Final OA — Pending Feb 28, 2023
18165226 METHODS FOR DETERMINING A LOCATION OF A TARGET NUCLEIC ACID IN A BIOLOGICAL SAMPLE SISSON, BRADLEY L 1682 §103 Final Rejection 49d Pending Feb 06, 2023
18154516 DEVICES, SYSTEMS, AND METHODS FOR DIRECTING FLUID FLOW TURK, NEIL N 1798 Other Non-Final OA — Pending Jan 13, 2023
18009093 METHODS FOR SPATIAL ANALYSIS USING BLOCKER OLIGONUCLEOTIDES LU, FRANK WEI MIN 1683 §112 Non-Final OA 59d overdue Pending Dec 08, 2022
17923007 SPATIAL TRANSCRIPTOMIC TRANSFER MODES VANN-OJUEKAIYE, KENDRA RAYCHELL 1682 §103 Final Rejection 31d overdue Pending Nov 03, 2022
18046457 COMPOSITIONS AND METHODS FOR USE WITH FIXED SAMPLES POHNERT, STEVEN C 1683 §103 Non-Final OA 139d overdue Pending Oct 13, 2022
17956596 METHODS AND KITS FOR IDENTIFYING, DIAGNOSING AND TREATING PROSTATE CARCINOMAS KIM, YOUNG J 1681 Other Final Rejection 1d overdue Pending Sep 29, 2022
17898240 SYSTEMS AND METHODS FOR IDENTIFYING ADAPTIVE IMMUNE CELL CLONOTYPES LEVERETT, MARY CHANG 1687 §103 Non-Final OA 21d Pending Aug 29, 2022
17891641 METHODS FOR DETERMINING A LOCATION OF AN ANALYTE IN A BIOLOGICAL SAMPLE GUSSOW, ANNE 1683 Other Non-Final OA 5d overdue Pending Aug 19, 2022
17801078 METHODS TO COMBINE FIRST AND SECOND STRAND cDNA SYNTHESIS FOR SPATIAL ANALYSIS CASH, KAILEY ELIZABETH 1683 §103 Non-Final OA 15d overdue Pending Aug 19, 2022
17820560 METHODS FOR PROCESSING NUCLEIC ACID MOLECULES ZHANG, KAIJIANG 1684 §102 Non-Final OA 26d Pending Aug 17, 2022
17889025 DE-CROSSLINKING COMPOUNDS AND METHODS OF USE FOR SPATIAL ANALYSIS HAQ, SHAFIQUL 1678 §103 Final Rejection 16d overdue Pending Aug 16, 2022
17881086 ANALYTE CAPTURE FROM AN EMBEDDED BIOLOGICAL SAMPLE GRAY, JESSICA 1682 Other Final Rejection 99d overdue Pending Aug 04, 2022
17877664 COMPOSITIONS AND METHODS FOR ANALYSIS USING NUCLEIC ACID PROBES AND BLOCKING SEQUENCES SISSON, BRADLEY L 1682 §112 Final Rejection 21d Pending Jul 29, 2022
17877760 ONE STEP IN SITU ROLLING CIRCLE AMPLIFICATION ASSAY VANN-OJUEKAIYE, KENDRA RAYCHELL 1682 Other Final Rejection 6d Pending Jul 29, 2022
17812075 METHODS FOR SAMPLE TRANSFER FOR IN SITU ANALYSIS LU, FRANK WEI MIN 1683 §112 Final Rejection 4d overdue Pending Jul 12, 2022
17843758 METHODS TO GENERATE CIRCULARIZABLE PROBES IN SITU BUNKER, AMY M 1684 Other Non-Final OA 85d overdue Pending Jun 17, 2022
17835796 METHODS AND SYSTEMS FOR PROCESSING POLYNUCLEOTIDES RAYMONDA, MATTHEW HAROLD 1684 Other Non-Final OA 70d overdue Pending Jun 08, 2022
17831835 METHODS FOR ENRICHING NUCLEIC ACID LIBRARIES FOR TARGET MOLECULES THAT DO NOT PRODUCE ARTEFACTUAL ANTISENSE READS RAYMONDA, MATTHEW HAROLD 1684 §103 Non-Final OA 147d overdue Pending Jun 03, 2022
17829072 METHODS AND COMPOSITIONS FOR ANALYTE DETECTION AND PROBE RESOLUTION RAYMONDA, MATTHEW HAROLD 1684 §103 Non-Final OA 37d overdue Pending May 31, 2022
17752679 VISUALIZATION OF THE ANTIGEN BINDING PROFILE FOR A SET OF CLONOTYPES BEVERIDGE, CONNOR HAMMOND 1687 §103 Non-Final OA 70d overdue Pending May 24, 2022
17738538 CONTROLLED CROSSLINKING OF BIOMOLECUES IN SITU KENNEDY, SARAH JANE 1682 §103 Non-Final OA 33d Pending May 06, 2022
17724977 METHODS AND DEVICES FOR SPATIAL ASSESSMENT OF RNA QUALITY VANN-OJUEKAIYE, KENDRA RAYCHELL 1682 §103 Final Rejection 22d overdue Pending Apr 20, 2022
17685033 METHODS AND COMPOSITIONS FOR MODIFYING PRIMARY PROBES IN SITU BELLAH, JEFFREY LAWRENCE 1683 §103 Non-Final OA 32d overdue Pending Mar 02, 2022
17517287 PARTITIONING AND PROCESSING OF ANALYTES AND OTHER SPECIES GUSSOW, ANNE 1683 §103 Non-Final OA 43d overdue Pending Nov 02, 2021
17476398 METHODS AND SYSTEMS FOR BARCODE ERROR CORRECTION STRIEGEL, THEODORE CHARLES 1685 §103 Final Rejection 4d overdue Pending Sep 15, 2021
17476395 SYSTEMS AND METHODS FOR BARCODE DESIGN AND DECODING BUNKER, AMY M 1684 §103 Non-Final OA 79d overdue Pending Sep 15, 2021
17279025 HIGH THROUGHPUT EPITOPE IDENTIFICATION AND T CELL RECEPTOR SPECIFICITY DETERMINATION USING LOADABLE DETECTION MOLECULES LUSI, ELLIS FOLLETT 1677 §103 Non-Final OA 46d Pending Mar 23, 2021
17271995 INCREASING SPATIAL ARRAY RESOLUTION GIAMMONA, FRANCESCA FILIPPA 1681 §103 Final Rejection 33d Pending Feb 26, 2021
17271866 Methods for Generating Spatially Barcoded Arrays GIAMMONA, FRANCESCA FILIPPA 1681 §103 Non-Final OA 36d overdue Pending Feb 26, 2021
17165808 PROBES AND METHODS OF USING SAME SISSON, BRADLEY L 1682 Other Final Rejection 5d overdue Pending Feb 02, 2021
16951864 PIPELINE FOR SPATIAL ANALYSIS OF ANALYTES STRIEGEL, THEODORE CHARLES 1685 §103 Non-Final OA 15d overdue Pending Nov 18, 2020
17033218 METHODS AND SYSTEMS FOR ASSOCIATING PHYSICAL AND GENETIC PROPERTIES OF BIOLOGICAL PARTICLES VANNI, GEORGE STEVEN 1686 Other Non-Final OA 50d overdue Pending Sep 25, 2020
16992569 SYSTEMS AND METHODS FOR USING THE SPATIAL DISTRIBUTION OF HAPLOTYPES TO DETERMINE A BIOLOGICAL CONDITION LIU, GUOZHEN 1686 §101 Final Rejection 30d Pending Aug 13, 2020

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Data sourced from USPTO Patent File Wrapper (daily) and Office Action Archive (weekly). Analysis generated by IP Author.

Data: USPTO Patent File Wrapper (daily) • Office Action Archive (weekly) • 89M+ prosecution events

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