Prosecution Insights
Prosecution Insights
Technology area: Biotechnology & Pharmaceuticals
103 pending office actions • 40 art units • 90 examiners • 0 of 103 (0%) have an AI response strategy ready • 112 patents granted in the last 365 days
Hoffmann La-Roche Inc. maintains 1 pending office action in the Communications technology area. This matter is assigned to a distinct examiner working within 1 distinct art unit. GEBRESLASSIE, WINTA is the busiest examiner for this portfolio, currently overseeing the pending matter.
The presence of a single pending office action indicates a narrow prosecution window within the Communications sector. Because a single examiner is involved, the outcome of the current portfolio depends on the resolution of this specific action. This concentration allows for a targeted response strategy within the designated art unit.
Based on the USPTO statutory response window for each pending office action. 32 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 32 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 only | 1 (1%) |
| §101 + other | 11 (11%) |
| §103 only | 20 (19%) |
| §102 only | 5 (5%) |
| §112 only | 12 (12%) |
| Double-patenting only | 7 (7%) |
| Double-patenting + other | 16 (16%) |
| Multi-statute (no §101) | 29 (28%) |
| No statute on record | 2 (2%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| HUYNH, PHUONG N | 4 | 65.7% | +53.6% |
| REILLY, SOPHIA JANE | 3 | 60.8% | +49.2% |
| BRISTOL, LYNN ANNE | 3 | 63.4% | +39.8% |
| ALSOMAIRY, SARAH ABDOALATIF | 2 | 57.8% | +30.2% |
| NESTOR, DONNA MICHELLE | 2 | 56.6% | +44.2% |
| DEBERRY, REGINA M | 2 | 50.1% | +30.6% |
| LAU, JONATHAN S | 2 | 63.7% | -17.3% |
| COUGHLIN, MATTHEW P | 2 | 71.3% | +12.4% |
| DENT, ALANA HARRIS | 2 | 44.2% | +32.0% |
| AKANBI, ISIAKA O | 1 | 76.6% | +22.8% |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18150553 | Process for the preparation of oligonucleotides using modified oxidation protocol | LAU, JONATHAN S | 114d overdue |
| 18117966 | NOVEL HETEROCYCLIC COMPOUNDS | MCDOWELL, BRIAN E | 72d overdue |
| 18176062 | CRISPR/Cas9 MULTIPLEX KNOCKOUT OF HOST CELL PROTEINS | FLINDERS, JEREMY C | 53d overdue |
| 17186816 | METHOD FOR VERIFYING CULTIVATION DEVICE PERFORMANCE | MINCHELLA, KAITLYN L | 49d overdue |
| 18482264 | MACHINE LEARNING-BASED PREDICTION OF TREATMENT REQUIREMENTS FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION (NAMD) | SORRIN, AARON JOSEPH | 32d overdue |
| 18045037 | LARGE MOLECULE UNSPECIFIC CLEARANCE ASSAY | SVEIVEN, MICHAEL CAMERON | 23d overdue |
| 17810426 | SINGLE-USE CELL CULTURE CONTAINER WITH ONE OR MORE IN-SITU ONLINE SENSORS | BOWERS, NATHAN ANDREW | 3d overdue |
| 17764763 | MEANS AND METHODS FOR ASSESSING HUNTINGTON'S DISEASE (HD) | COVINGTON, AMANDA R | 5d |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17507029 | THERAPEUTIC MULTISPECIFIC POLYPEPTIDES ACTIVATED BY POLYPEPTIDE CHAIN EXCHANGE | HUYNH, PHUONG N | 22d overdue |
| 17507511 | ACTIVATABLE THERAPEUTIC MULTISPECIFIC POLYPEPTIDES WITH EXTENDED HALF-LIFE | HUYNH, PHUONG N | 11d overdue |
| 18455029 | PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | COUGHLIN, MATTHEW P | 2d overdue |
| 17937440 | BISPECIFIC ANTIBODIES COMPRISING A MODIFIED C-TERMINAL CROSSFAB FRAGMENT | BRISTOL, LYNN ANNE | 34d |
| 18051307 | PREDICTING RESPONSE TO PD-1 AXIS INHIBITORS | BRISTOL, LYNN ANNE | 48d |
| 19107911 | INSPECTION SYSTEM AND METHOD FOR A CLOSED MEDICAL CONTAINER | AKANBI, ISIAKA O | — |
| 18844654 | COMBINATION THERAPIES FOR BREAST CANCER | REILLY, SOPHIA JANE | — |
| 18802257 | PROCESSES FOR THE PREPARATION OF 1,2,3,5,6,7-HEXAHYDRO-S-INDACENE DERIVATAIVES | REILLY, SOPHIA JANE | — |
| Art Unit | Apps |
|---|---|
| 1643 | 6 |
| 1641 | 5 |
| 1624 | 4 |
| 1626 | 4 |
| 1678 | 4 |
| 1675 | 3 |
| 1647 | 3 |
| 1627 | 3 |
| 3791 | 3 |
| 1693 | 3 |
| App # | Title | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|
| 19107911 | INSPECTION SYSTEM AND METHOD FOR A CLOSED MEDICAL CONTAINER | AKANBI, ISIAKA O | — | §102 | Non-Final OA | — | Pending | Feb 28, 2025 |
| 19059186 | QUANTIFYING AMYLOID-RELATED IMAGING ABNORMALITIES (ARIA) IN ALZHEIMER'S PATIENTS | MALDONADO, STEVEN | 3797 | §103 | Final Rejection | 23d overdue | Pending | Feb 20, 2025 |
| 19059182 | SEGMENTING AND DETECTING AMYLOID-RELATED IMAGING ABNORMALITIES (ARIA) IN ALZHEIMER'S PATIENTS | GROSS, JASON PATRICK | 3797 | §101§103 | Final Rejection | — | Pending | Feb 20, 2025 |
| 19050991 | MACHINE LEARNING ENABLED LOCALIZATION OF FOVEAL CENTER IN SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY VOLUME SCANS | HUYNH, VAN D | — | §103 | Non-Final OA | — | Pending | Feb 11, 2025 |
| 19043123 | DIAGNOSTIC TOOL FOR REVIEW OF DIGITAL PATHOLOGY IMAGES | DESIRE, GREGORY M | — | §102 | Non-Final OA | — | Pending | Jan 31, 2025 |
| 18987316 | MACROCYCLIC INHIBITORS OF KRAS FOR THE TREATMENT OF CANCER | HERNANDEZ, JACKSON J | — | §103 | Non-Final OA | — | Pending | Dec 19, 2024 |
| 18875050 | OCT RETINAL VOLUMETRIC MEASUREMENTS BASED ON ETDRS GRID | ADEDIRAN, ABDUL -SAMAD A | — | §102§103 | Non-Final OA | — | Pending | Dec 13, 2024 |
| 18865278 | NEW INDAZOLE DERIVATIVES | OTTON, ALICIA L | — | DP | Non-Final OA | — | Pending | Nov 12, 2024 |
| 18865274 | COMBINATION OF ALLOSTERIC AND ORTHOSTERIC EGFR INHIBITORS FOR THE TREATMENT OF CANCER | SEAMAN, D MARGARET M | — | §102 | Non-Final OA | — | Pending | Nov 12, 2024 |
| 18923478 | SEGMENTATION OF OPTICAL COHERENCE TOMOGRAPHY (OCT) IMAGES | GARCIA, SANTIAGO | — | §103 | Non-Final OA | — | Pending | Oct 22, 2024 |
| 18885056 | FORMS OF PYRIDO[1,2-A]PYRIMIDIN-4-ONE DERIVATIVES, ITS FORMULATION AND ITS PROCESS OF MAKING | RAHMANI, NILOOFAR | — | DP | Non-Final OA | — | Pending | Sep 13, 2024 |
| 18844654 | COMBINATION THERAPIES FOR BREAST CANCER | REILLY, SOPHIA JANE | — | §103§112 | Non-Final OA | — | Pending | Sep 06, 2024 |
| 18844371 | PYRIDO[1,2-A]PYRIMIDIN-4-ONE DERIVATIVES | FERGUSON, JALISA HOLMES | — | §112 | Non-Final OA | — | Pending | Sep 05, 2024 |
| 18816550 | PROCESSES FOR THE PREPARATION OF PHENYLTETRAHYDROFURAN COMPOUNDS | WHITE, DAWANNA SHAR-DAY | — | §103 | Non-Final OA | — | Pending | Aug 27, 2024 |
| 18802257 | PROCESSES FOR THE PREPARATION OF 1,2,3,5,6,7-HEXAHYDRO-S-INDACENE DERIVATAIVES | REILLY, SOPHIA JANE | — | §102§103§112 | Non-Final OA | — | Pending | Aug 13, 2024 |
| 18832840 | HETEROCYCLIC COMPOUNDS | NOLAN, JASON MICHAEL | — | §112 | Non-Final OA | — | Pending | Jul 24, 2024 |
| 18743437 | PROGNOSTIC MODELS FOR PREDICTING FIBROSIS DEVELOPMENT | YENTRAPATI, AVINASH | 2672 | §103 | Non-Final OA | — | Pending | Jun 14, 2024 |
| 18672669 | QUANTIFICATION OF LOW AMOUNTS OF ANTIBODY SIDE-PRODUCTS | COUNTS, GARY W | — | §112 | Non-Final OA | — | Pending | May 23, 2024 |
| 18670375 | METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA | DONOGHUE, BRITTNEY ERIN | 1675 | §103 | Final Rejection | — | Pending | May 21, 2024 |
| 18668810 | COMBINATION THERAPY OF ANTI-TYRP1/ANTI-CD3 BISPECIFIC ANTIBODIES AND TYRP1-SPECIFIC ANTIBODIES | ALSOMAIRY, SARAH ABDOALATIF | — | §103§112DP | Non-Final OA | — | Pending | May 20, 2024 |
| 18665776 | SYNTHESIS OF 2'-(7,7-dimethyl-1'H,7H-spiro[furo[3,4-b]pyridine-5,4'-piperidin]-1'-yl)-1,3-dihydro-4'H-spiro[indene-2,5'-[1,3]oxazol]-4'-one | NESTOR, DONNA MICHELLE | — | §103§112Other | Non-Final OA | — | Pending | May 16, 2024 |
| 18665390 | HETEROCYCLIC NLRP3 INHIBITORS | WILLIS, DOUGLAS M | — | §102§112 | Non-Final OA | — | Pending | May 15, 2024 |
| 18664086 | STIRRER SYSTEM | HASSAN, LIBAN M | — | §103 | Non-Final OA | — | Pending | May 14, 2024 |
| 18659831 | PHARMACEUTICAL COMBINATIONS FOR TREATMENT OF HBV | KONOPKA, CATHERINE ANNE | — | §102§103§112 | Non-Final OA | — | Pending | May 09, 2024 |
| 18653975 | USE OF QUINAZOLINONE COMPOUND FOR THE TREATMENT OF CANCER | RICCI, CRAIG D | — | §103§112DP | Non-Final OA | — | Pending | May 03, 2024 |
| 18645245 | Method for purifying PEGylated erythropoietin | DEBERRY, REGINA M | 1647 | DP | Final Rejection | — | Pending | Apr 24, 2024 |
| 18627727 | COMBINED ADMINISTRATION | NATARAJAN, MEERA | — | §103 | Non-Final OA | — | Pending | Apr 05, 2024 |
| 18626665 | CYCLOHEPTA-THIENO-DIAZEPINE DERIVATIVES AS GABA A GAMMA1 PAM | BAUER, BRIANNA LEE | 1623 | §112 | Non-Final OA | — | Pending | Apr 04, 2024 |
| 18693273 | KIT FOR FORMING A MICROPLATE ASSEMBLY FOR ABSORBANCE MEASUREMENTS OF LIQUID SAMPLES | JARRETT, LORE RAMILLANO | — | §103§112 | Non-Final OA | — | Pending | Mar 19, 2024 |
| 18600323 | ANTI-TIM3 ANTIBODIES AND METHODS OF USE | BRISTOL, LYNN ANNE | — | §102§112Other | Non-Final OA | — | Pending | Mar 08, 2024 |
| 18581036 | METHOD FOR CLASSIFYING QUALITY OF BIOLOGICAL SENSOR DATA | DUONG, HIEN LUONGVAN | — | §101§103 | Non-Final OA | — | Pending | Feb 19, 2024 |
| 18443690 | OBJECT RECONSTRUCTION IN DIGITAL IMAGES | LANTZ, KARSTEN FOSTER | 2664 | §103 | Final Rejection | — | Pending | Feb 16, 2024 |
| 18441878 | E3 UBIQUITIN LIGASE (UBE3A) PROTEIN TARGETS | GORDON, MELENIE LEE | 1651 | §101§112 | Non-Final OA | 13d | Pending | Feb 14, 2024 |
| 18430887 | METHOD FOR DETERMINING THE AMOUNT OF A THERAPEUTIC ANTIBODY IN THE BRAIN | HUYNH, PHUONG N | 1641 | §112DP | Non-Final OA | — | Pending | Feb 02, 2024 |
| 18292865 | PARTICLE COUNTER AND METHOD FOR COUNTING PARTICLES IN A STERILIZATION TUNNEL OF A MEDICAMENT FILLING SYSTEM | CHEN, CHANGRU | 1796 | §103 | Non-Final OA | — | Pending | Jan 26, 2024 |
| 18424571 | METHOD FOR THE DETECTION OF ORGAN DERIVED EXTRACELLULAR VESICLES | MARCSISIN, ELLEN JEAN | — | §103§112 | Non-Final OA | — | Pending | Jan 26, 2024 |
| 18422786 | HALOACETHYDRAZIDES USEFUL AS AEP INHIBITORS | COLEMAN, BRENDA LIBBY | 1624 | §112 | Final Rejection | — | Pending | Jan 25, 2024 |
| 18579293 | PREDICTION OF PHARMACOKINETIC CURVES | HAYNES, DAWN TRINAH | 3627 | §101§102§103 | Non-Final OA | — | Pending | Jan 12, 2024 |
| 18542088 | SPATIAL ANALYSIS OF MITOTIC FIGURES IN HISTOPATHOLOGICAL IMAGES | AUGUSTIN, MARCELLUS | 2682 | §103 | Non-Final OA | 12d | Pending | Dec 15, 2023 |
| 18533539 | METHODS AND COMPOSITIONS COMPRISING A BRAF INHIBITOR AND A PD-1 BINDING ANTAGONIST | DRISCOLL, MAUREEN VARINA | — | §103§112DP | Non-Final OA | — | Pending | Dec 08, 2023 |
| 18533714 | BISPECIFIC ANTI-CCL2 ANTIBODIES | NICKOL, GARY B | — | DP | Non-Final OA | — | Pending | Dec 08, 2023 |
| 18533710 | SOLID FORMS OF (3R)-N-[2-CYANO-4-FLUORO-3-(3-METHYL-4-OXO-QUINAZOLIN-6-YL)OXY-PHENYL]-3-FLUORO-PYRROLIDINE-1-SULFONAMIDE | HSU, GRACE CHING | 1627 | §102§103§112 | Non-Final OA | 27d | Pending | Dec 08, 2023 |
| 18525536 | METHYLQUINAZOLINONE DERIVATIVES | MCKOY, QUINCY ANDRE | 1626 | §102 | Non-Final OA | 86d overdue | Pending | Nov 30, 2023 |
| 18506808 | LOGIC-BASED TYPING OF MULTIPLE SCLEROSIS SUBJECTS BASED ON CODED DATA | SKROBARCZYK III, ROBERT ANTHONY | 3792 | §101§103 | Final Rejection | — | Pending | Nov 10, 2023 |
| 18490967 | HETEROCYCLIC COMPOUNDS | BRAUN, MADELINE E | 1624 | §102§112DPOther | Non-Final OA | — | Pending | Oct 20, 2023 |
| 18489274 | MODIFIED MAMMALIAN CELLS | WILSON, MICHAEL C | 1656 | §112 | Non-Final OA | — | Pending | Oct 18, 2023 |
| 18482264 | MACHINE LEARNING-BASED PREDICTION OF TREATMENT REQUIREMENTS FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION (NAMD) | SORRIN, AARON JOSEPH | 2672 | §102§103§112 | Final Rejection | 32d overdue | Pending | Oct 06, 2023 |
| 18479596 | PROCESSES FOR MAKING BICYCLIC KETONE COMPOUNDS | NESTOR, DONNA MICHELLE | 1627 | §103 | Final Rejection | — | Pending | Oct 02, 2023 |
| 18282506 | COMPUTER-IMPLEMENTED METHODS AND SYSTEMS FOR QUANTITATIVELY DETERMINING A CLINICAL PARAMETER | GLOVER, NELSON ALEXANDER | 3791 | §101§102§103§112 | Non-Final OA | 9d | Pending | Sep 15, 2023 |
| 18331536 | Novel Synthesis of Phosphorodithioate Oligonucleotides | LAU, JONATHAN S | 1693 | §102§103§112 | Non-Final OA | 28d | Pending | Aug 29, 2023 |
| 18455029 | PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | COUGHLIN, MATTHEW P | 1626 | §112DP | Final Rejection | 2d overdue | Pending | Aug 24, 2023 |
| 18454131 | REGENERATION AND MULTIPLE USE OF DEPTH FILTERS | KURTZ, BENJAMIN M | 1779 | §103§112 | Non-Final OA | — | Pending | Aug 23, 2023 |
| 18454315 | BENZOTHIAZOLYL BICYCLO[1.1.1]PENTANE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | GAUGER, PAUL RANDALL | 1629 | Other | Non-Final OA | 28d | Pending | Aug 23, 2023 |
| 18451352 | METHOD FOR RESOLVING COMPLEX, MULTISTEP ANTIBODY INTERACTIONS | VOLKOV, ALEXANDER ALEXANDROVIC | 1677 | §103§112 | Final Rejection | 39d | Pending | Aug 17, 2023 |
| 18449862 | PROCESS FOR THE DE-TRITYLATION OF OLIGONUCLEOTIDES | OLSON, ANDREA STEFFEL | 1693 | §103 | Final Rejection | 31d overdue | Pending | Aug 15, 2023 |
| 18546087 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER | HABTE, KAHSAY | 1624 | §112 | Non-Final OA | 37d overdue | Pending | Aug 10, 2023 |
| 18339960 | METHODS FOR TREATING MULTIPLE SCLEROSIS WITH OCRELIZUMAB | ESSEX, LAURA ANN | 1675 | §103§112 | Non-Final OA | 83d | Pending | Jun 22, 2023 |
| 18210991 | NEW ARYL-PYRIDO-PYRIMIDIN-ONE DERIVATIVES | LEE, CHIHYI NMN | 1628 | §103 | Final Rejection | 32d overdue | Pending | Jun 16, 2023 |
| 18208024 | COMBINATION THERAPIES FOR TREATMENT OF HER2 CANCER | KUCKLA, ANNA GRACE | 1626 | §103 | Final Rejection | — | Pending | Jun 09, 2023 |
| 18255076 | NEW INDAZOLE DERIVATIVES | DAHLIN, HEATHER RAQUEL | 1629 | §103DP | Final Rejection | 150d overdue | Pending | May 30, 2023 |
| 18037071 | FAB HIGH MANNOSE GLYCOFORMS | ALSOMAIRY, SARAH ABDOALATIF | 1646 | §102§103§112 | Non-Final OA | — | Pending | May 15, 2023 |
| 18250977 | INHIBITORS OF ANGIOGENIC FACTORS | BRADLEY, CHRISTINA | 1654 | §102§103§112 | Non-Final OA | — | Pending | Apr 27, 2023 |
| 18140583 | IN SILICO PREDICTIONS OF AMYLOID-RELATED IMAGING ABNORMALITIES | THOMPSON, MILANA KAYE | — | §103 | Non-Final OA | — | Pending | Apr 27, 2023 |
| 18301187 | NON-COVALENT PROTEIN-HYALURONAN CONJUGATES FOR LONG-ACTING OCULAR DELIVERY | SAOUD, CHRISTINE J | 1645 | §102§103§112DP | Non-Final OA | — | Pending | Apr 14, 2023 |
| 18301180 | HYALURONIC ACID BINDING DERIVATIVES OF VERSICAN (VG1) FOR LONG ACTING DELIVERY OF THERAPEUTICS | DEBERRY, REGINA M | 1647 | §102§103§112DP | Non-Final OA | — | Pending | Apr 14, 2023 |
| 18188266 | MACHINE LEARNING PREDICTION OF INJECTION FREQUENCY IN PATIENTS WITH MACULAR EDEMA | FRUMKIN, JESSE P | — | §101§102§112 | Non-Final OA | — | Pending | Mar 22, 2023 |
| 18117966 | NOVEL HETEROCYCLIC COMPOUNDS | MCDOWELL, BRIAN E | 1624 | §102§112 | Final Rejection | 72d overdue | Pending | Mar 06, 2023 |
| 18176062 | CRISPR/Cas9 MULTIPLEX KNOCKOUT OF HOST CELL PROTEINS | FLINDERS, JEREMY C | 1684 | §103§112 | Final Rejection | 53d overdue | Pending | Feb 28, 2023 |
| 18153234 | ASSAYS FOR FIXED DOSE COMBINATIONS | GABEL, GAILENE | 1678 | §102§103§112 | Non-Final OA | — | Pending | Jan 11, 2023 |
| 18014729 | ANTIBODIES WHICH BIND TO CANCER CELLS AND TARGET RADIONUCLIDES TO SAID CELLS | CABRAL, ROBERT S | 1614 | Other | Non-Final OA | — | Pending | Jan 05, 2023 |
| 18150466 | ALTERNATIVE SURFACTANTS AS STABILIZERS FOR THERAPEUTIC PROTEIN FORMULATIONS | CHEONG, CHEOM-GIL | 1645 | §102§112 | Non-Final OA | 13d | Pending | Jan 05, 2023 |
| 18150553 | Process for the preparation of oligonucleotides using modified oxidation protocol | LAU, JONATHAN S | 1693 | §102§103§112 | Final Rejection | 114d overdue | Pending | Jan 05, 2023 |
| 18068407 | AMIDOPYRIMIDONE DERIVATIVES | REILLY, SOPHIA JANE | 1627 | §103§112DP | Non-Final OA | — | Pending | Dec 19, 2022 |
| 18066529 | PROTEASE-ACTIVATED T CELL BISPECIFIC ANTIBODIES | CHATTIN, AMY MARIE | 1643 | §112Other | Non-Final OA | 26d | Pending | Dec 15, 2022 |
| 18065570 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF MICRORNA RELATED DISEASES | SHIN, DANA H | 1635 | §102§103§112DP | Non-Final OA | 87d overdue | Pending | Dec 13, 2022 |
| 17928162 | METHOD OF DETERMINING A RISK OF MORTALITY OF A CANCER PATIENT, METHOD OF ASSESSING AN ANTI-CANCER THERAPY, METHOD OF SELECTING CANCER PATIENTS FOR TREATMENT | LUO, JAMMY NMN | 1686 | §101§103 | Non-Final OA | — | Pending | Nov 28, 2022 |
| 17986737 | PATHOLOGY PREDICTION BASED ON SPATIAL FEATURE ANALYSIS | ISLAM, MEHRAZUL NMN | 2662 | §103 | Final Rejection | — | Pending | Nov 14, 2022 |
| 17997905 | PREDICTING RESPONSE TO PD-1 AXIS INHIBITORS | GRAY, JESSICA | 1682 | §103DP | Final Rejection | — | Pending | Nov 03, 2022 |
| 18051307 | PREDICTING RESPONSE TO PD-1 AXIS INHIBITORS | BRISTOL, LYNN ANNE | 1643 | §112 | Non-Final OA | 48d | Pending | Oct 31, 2022 |
| 17976651 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | COUGHLIN, MATTHEW P | 1626 | §102§112 | Non-Final OA | — | Pending | Oct 28, 2022 |
| 18045037 | LARGE MOLECULE UNSPECIFIC CLEARANCE ASSAY | SVEIVEN, MICHAEL CAMERON | 1678 | §101§103 | Non-Final OA | 23d overdue | Pending | Oct 07, 2022 |
| 17937440 | BISPECIFIC ANTIBODIES COMPRISING A MODIFIED C-TERMINAL CROSSFAB FRAGMENT | BRISTOL, LYNN ANNE | 1643 | §112 | Non-Final OA | 34d | Pending | Sep 30, 2022 |
| 17810426 | SINGLE-USE CELL CULTURE CONTAINER WITH ONE OR MORE IN-SITU ONLINE SENSORS | BOWERS, NATHAN ANDREW | 1799 | §103§112 | Final Rejection | 3d overdue | Pending | Jul 01, 2022 |
| 17845960 | EXTENDED REALITY SYSTEM TO TREAT SUBJECTS ASSOCIATED WITH AUTISM SPECTRUM DISORDER | MATTHEWS, CHRISTINE HOPKINS | 3791 | §103§112 | Final Rejection | — | Pending | Jun 21, 2022 |
| 17732347 | MULTISPECIFIC ANTIBODIES | SCHWECHTER, BRANDON ROSS | 1674 | §103§112Other | Non-Final OA | — | Pending | Apr 28, 2022 |
| 17767810 | Artificial Transmembrane Proteins for Detecting Intracellular or Intravesicular Biomolecular Interactions | BUNNER, BRIDGET E | 1647 | §102§112 | Final Rejection | — | Pending | Apr 08, 2022 |
| 17764763 | MEANS AND METHODS FOR ASSESSING HUNTINGTON'S DISEASE (HD) | COVINGTON, AMANDA R | 3686 | §101 | Final Rejection | 5d | Pending | Mar 29, 2022 |
| 17655741 | REDUCTION OF APPLICATION-RELATED SIDE REACTION OF A THERAPEUTIC ANTIBODY | BALLARD, KIMBERLY | 1675 | §102§103§112DP | Non-Final OA | — | Pending | Mar 21, 2022 |
| 17760835 | Improvements in Personalized Healthcare for Patients with Movement Disorders | BALAJI, KAVYA SHOBANA | 3791 | §103§112 | Non-Final OA | — | Pending | Mar 16, 2022 |
| 17630046 | DOSAGE AND ADMINISTRATION REGIMEN FOR THE TREATMENT OR PREVENTION OF C5-RELATED DISEASES BY THE USE OF THE ANTI-C5 ANTIBODY CROVALIMAB | DENT, ALANA HARRIS | 1643 | DP | Final Rejection | — | Pending | Jan 25, 2022 |
| 17630050 | DOSAGE AND ADMINISTRATION REGIMEN FOR THE TREATMENT OR PREVENTION OF C5-RELATED DISEASES BY THE USE OF THE ANTI-C5 ANTIBODY CROVALIMAB | DENT, ALANA HARRIS | 1643 | DP | Final Rejection | — | Pending | Jan 25, 2022 |
| 17559934 | METHOD FOR THE PRODUCTION OF AN ANTIBODY | BURKHART, MICHAEL D | 1638 | §101§112 | Final Rejection | — | Pending | Dec 22, 2021 |
| 17559926 | MAMMALIAN CELL LINES WITH SIRT-1 GENE KNOCKOUT | HASAN, KHALEDA B | 1636 | §103 | Final Rejection | — | Pending | Dec 22, 2021 |
| 17542358 | PAPD5 AND PAPD7 INHIBITORS FOR TREATING A HEPATITIS B INFECTION | PERREIRA, MELISSA JEAN | 1618 | §102§112DP | Non-Final OA | — | Pending | Dec 03, 2021 |
| 17507511 | ACTIVATABLE THERAPEUTIC MULTISPECIFIC POLYPEPTIDES WITH EXTENDED HALF-LIFE | HUYNH, PHUONG N | 1641 | §102 | Non-Final OA | 11d overdue | Pending | Oct 21, 2021 |
| 17507029 | THERAPEUTIC MULTISPECIFIC POLYPEPTIDES ACTIVATED BY POLYPEPTIDE CHAIN EXCHANGE | HUYNH, PHUONG N | 1641 | §102§112DP | Non-Final OA | 22d overdue | Pending | Oct 21, 2021 |
| 17488649 | SPR-BASED BINDING ASSAY FOR THE FUNCTIONAL ANALYSIS OF MULTIVALENT MOLECULES | IVICH, FERNANDO NMN | 1678 | §112 | Non-Final OA | 35d | Pending | Sep 29, 2021 |
| 17362038 | Method for selecting cells based on CRISPR/Cas-mediated integration of a detectable tag to a target protein | RYAN, DOUGLAS CHARLES | 1635 | §103§112 | Final Rejection | — | Pending | Jun 29, 2021 |
| 17338569 | COMBINATION THERAPY OF DIFFUSE LARGE B-CELL LYMPHOMA COMPRISING AN ANTI-CD79B IMMUNOCONJUGATES, AN ALKYLATING AGENT AND AN ANTI-CD20 ANTIBODY | SKOKO III, JOHN JOSEPH | 1643 | §103DP | Non-Final OA | — | Pending | Jun 03, 2021 |
| 17335702 | AFFINITY CHROMATOGRAPHY PURIFICATION WITH LOW CONDUCTIVITY WASH BUFFER | HUYNH, PHUONG N | 1641 | DP | Non-Final OA | — | Pending | Jun 01, 2021 |
| 17335680 | Method for the reduction of host cell proteins in affinity chromatography | KIM, YUNSOO | 1641 | §112 | Non-Final OA | 8d overdue | Pending | Jun 01, 2021 |
| 17199195 | CSF-1R ANTIBODY FORMULATION | GAO, ASHLEY HARTMAN | 1678 | §103Other | Final Rejection | — | Pending | Mar 11, 2021 |
| 17186816 | METHOD FOR VERIFYING CULTIVATION DEVICE PERFORMANCE | MINCHELLA, KAITLYN L | 1685 | §101§103§112 | Non-Final OA | 49d overdue | Pending | Feb 26, 2021 |
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