Prosecution Insights
Last updated: August 06, 2026

Mcneill Pllc

48 pending office actions • 34 clients • 46 examiners • 24 art units • 0 of 48 (0%) have an AI response strategy ready

Quality Metrics (n=1943 apps, methodology: how we score firms)

71.3%
Allowance Rate
n=1943
+0.58σ
Allowance Rate (norm)
n=1943
3.6
OAs to Allowance
n=640
-0.16σ
OAs to Allow (norm)
n=640
1059 days
Time to Allowance
n=640
+30.3pp
Interview Lift
n=1943
28.4%
RCE Rate
n=1943
1.0%
Appeal Rate
n=1943

Rejection Performance (% of received rejections ultimately overcome)

71.1%
§101 Overcome
n=90
64.6%
§102 Overcome
n=297
63.4%
§103 Overcome
n=472
69.6%
§112 Overcome
n=578

Specialization & Scale

A61K, A61P, C07K
Top CPC Subclasses
61%
Top-3 CPC Share
n=1943
40
Practitioners
n=1943
48.6
Apps / Practitioner
n=1943

Portfolio Summary

48
Total Pending OAs
36
Non-Final OAs
12
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 16 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

10
Overdue
1
Due this week
3
Due this month
1
Due in next 60 days
1
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 16 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (10)Due ≤ 7 days (1)Due ≤ 30 days (3)Due ≤ 60 days (1)Due later (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

14
Hard (29%)
24
Medium (50%)
10
Easy (21%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other3 (6%)
§103 only12 (25%)
§102 only1 (2%)
§112 only8 (17%)
Double-patenting only2 (4%)
Double-patenting + other11 (23%)
Multi-statute (no §101)11 (23%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

40
Life Sciences
83% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
1
Mechanical / Eng
2% of docket
7
Business / Other
15% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

480 h
Manual time on pending OAs
96 h
Time saved (low, 20%)
168 h
Time saved (mid, 35%)
4.2 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
HIBBERT, CATHERINE S 2 59.4% +47.9%
BUNNER, BRIDGET E 2 64.4% +20.1%
HUI, SAN MING R 1 59.3% +19.9%
BLUMEL, BENJAMIN P 1 70.7% +30.6%
OLSON, ANDREA STEFFEL 1 62.2% -11.9%
KATAKAM, SUDHAKAR 1 74.7% +23.5%
SCHMITT, MICHAEL J 1 56.6% +21.7%
SWITZER, JULIET CAROLINE 1 42.3% +53.8%
TOWNSLEY, SARA ELIZABETH 1 25.1% +48.8%
MOSHER, ERIC PARKER 1

Hard Cases (14)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18248079 CD19-Directed Chimeric Antigen Receptor Constructs HAMA, JOANNE 104d overdue
18035246 METHOD FOR ENZYMATIC AND/OR MICROBIAL PROCESSING OF WASTE COMPRISING RECIRCULATION OF PROCESS WATER ZINGARELLI, SANDRA 66d overdue
18302313 Heterocyclic Compounds as RET Kinase Inhibitors HSU, GRACE CHING 46d overdue
17921128 Glucocorticoid Receptor (GR) Modulators for Treating a SARS-COV-2 Virus HAVLIN, ROBERT H 23d overdue
18282402 TMEM173 saRNA Compositions and Methods of Use HUDSON, AMY ROSE 9d overdue
17637410 BLOOD GENE BIOMARKERS TO DIAGNOSE AND PREDICT ACUTE REJECTION IN LIVER TRANSPLANT RECIPIENTS MYERS, CARLA J 2d overdue
18050333 Methods of in Vitro Cell Delivery ZHU, JIANJIAN 6d
18251523 Combination Treatment of Cancer XIAO, YAN 8d

Interview Candidates (10)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17911808 Use of Anti-IL-6 Antibody, e.g., Clazakizumab for Treatment/Prevention of ARDS Associated with Coronavirus (COVID-19) Infection BUNNER, BRIDGET E 9d
18850107 Novel Salt of GLP-1 Receptor Agonist Compound, Preparation Method Thereof and Pharmaceutical Composition Comprising Thereof HUI, SAN MING R
18739986 AAV Vectors BLUMEL, BENJAMIN P
18708367 Gap Junction Modulators and Their Use for the Treatment of Age-Related Macular Degeneration KATAKAM, SUDHAKAR
18695940 SOS1 Inhibitor With Pyrido-Fused Six-Membered Ring Structure SCHMITT, MICHAEL J
18606338 Methods of Using Donor-Derived Cell-Free DNA to Distinguish Acute Rejection and Other Conditions in Liver Transplant Recipients SWITZER, JULIET CAROLINE
18690358 Hydroxamic Acid Compound Having ENPP1 Inhibitory Activity and Use Thereof TOWNSLEY, SARA ELIZABETH
18557182 COMBINATION OF BITTER RECEPTOR AGONIST AND GUT-SIGNALING COMPOUND HIBBERT, CATHERINE S

Client Portfolio (34 clients)

Top Art Units

Art UnitApps
16544
16474
16363
16423
16712
16292
16532
16582
16312
16272

Pending Office Actions

App #TitleClientExaminerArt UnitStatutesStatusDue inAIFiled
18850107 Novel Salt of GLP-1 Receptor Agonist Compound, Preparation Method Thereof and Pharmaceutical Composition Comprising Thereof Ildong Pharmaceutical Co., Ltd. HUI, SAN MING R §103 Non-Final OA Pending Sep 24, 2024
18739986 AAV Vectors Vigeneron GmbH BLUMEL, BENJAMIN P 1671 §112 Non-Final OA Pending Jun 11, 2024
18710370 Formulations and Methods for Treating Symptoms of Menopause Kindra Corporation OLSON, ANDREA STEFFEL §102§103§112DP Non-Final OA Pending May 15, 2024
18708367 Gap Junction Modulators and Their Use for the Treatment of Age-Related Macular Degeneration Breye Therapeutics Aps KATAKAM, SUDHAKAR §112 Non-Final OA Pending May 08, 2024
18695940 SOS1 Inhibitor With Pyrido-Fused Six-Membered Ring Structure Haihe Biopharma Co., Ltd. SCHMITT, MICHAEL J 1629 §102§112 Non-Final OA Pending Mar 27, 2024
18606338 Methods of Using Donor-Derived Cell-Free DNA to Distinguish Acute Rejection and Other Conditions in Liver Transplant Recipients Northwestern University SWITZER, JULIET CAROLINE §101§102§103§112 Non-Final OA Pending Mar 15, 2024
18690358 Hydroxamic Acid Compound Having ENPP1 Inhibitory Activity and Use Thereof Haihe Biopharma Co., Ltd. TOWNSLEY, SARA ELIZABETH 1629 §102§103§112Other Non-Final OA Pending Mar 08, 2024
18434621 CONJUGATES COMPRISING COVALENT BINDERS FOR TARGETING INTRACELLULAR PROTEINS Rayzebio, Inc. MOSHER, ERIC PARKER DP Non-Final OA Pending Feb 06, 2024
18431656 CONJUGATES COMPRISING COVALENT BINDERS FOR TARGETING INTRACELLULAR PROTEINS Rayzebio, Inc. DONOHUE, SEAN R §102§103DP Non-Final OA Pending Feb 02, 2024
18415032 Compositions and Methods for Treatment of Diseases Associated with Trinucleotide Repeats in Transcription Factor Four Intellia Therapeutics, Inc. REGA, KYLE THOMAS 1636 §103 Final Rejection 50d overdue Pending Jan 17, 2024
18579943 Compositions and Methods For Reducing Immune Intolerance and Treating Autoimmune Disorders Lapix Therapeutics, Inc. PIPIC, ALMA 1617 §103 Non-Final OA 53d Pending Jan 17, 2024
18569054 Improving the Efficiency of PAL-Catalyzed Protein Ligation By A Cascade Enzymatic Scheme Nanyang Technological University KOROTCHKINA, LIOUBOV G 1653 §103§112DP Non-Final OA Pending Dec 11, 2023
18513964 Methods for Reducing Risk of Onset of Acute Graft Versus Host Disease After Hematopoeitic Cell Transplantation Csl Behring LLC BEANE, RANDALL L 1654 §103 Final Rejection 70d Pending Nov 20, 2023
18511857 USE OF ANTIBODY-DRUG CONJUGATE IN COMBINATION WITH IMMUNE CHECKPOINT INHIBITOR IN TREATMENT OF UROTHELIAL CANCER Remegen Co., Ltd. EDGINGTONGIORDANO, FRANCESCA §102§103§112DP Non-Final OA Pending Nov 16, 2023
18507778 Compositions and Methods for Targeting Cancer Stem Cells The General Hospital Corporation COOK, LISA V 1642 §103§112DP Non-Final OA Pending Nov 13, 2023
18557661 Topical Compositions Comprising (Glyco)Sphingolipids and/or (Glyco)Ceramides Carbocode S.A. KRISHNAN, GANAPATHY 1693 §103§112 Non-Final OA Pending Oct 27, 2023
18557182 COMBINATION OF BITTER RECEPTOR AGONIST AND GUT-SIGNALING COMPOUND Aardvark Therapeutics, Inc. HIBBERT, CATHERINE S 1658 §103 Non-Final OA Pending Oct 25, 2023
18374902 PREPARATION AND PURIFICATION PROCESS OF MONOMETHYL AURISTAIN E COMPOUND Remegen Co., Ltd. HA, JULIE 1654 §112 Non-Final OA Pending Sep 29, 2023
18282402 TMEM173 saRNA Compositions and Methods of Use Mina Therapeutics Limited HUDSON, AMY ROSE 1636 §102§112 Non-Final OA 9d overdue Pending Sep 15, 2023
18450966 USE OF ANTIBODY-DRUG CONJUGATE TARGETING HER2 IN TREATMENT OF SPECIFIC BREAST CANCER Remegen Co., Ltd. PUTTLITZ, KARL J 1646 §103§112DPOther Non-Final OA Pending Aug 16, 2023
18339930 Compositions and Methods for Genetically Modifying CIITA in a Cell Intellia Therapeutics, Inc. SMALL, KATHERINE R 1633 §102 Non-Final OA Pending Jun 22, 2023
18334680 Glycan-Interacting Compounds and Methods of Use Seagen Inc. BORGEEST, CHRISTINA M 1675 §112Other Non-Final OA 13d Pending Jun 14, 2023
18332390 Compositions and Methods for Reducing MHC Class II in a Cell Intellia Therapeutics, Inc. KIM, TAEYOON 1631 §103 Non-Final OA Pending Jun 09, 2023
18253485 Method for Treating Antibody-Mediated Rejection Csl Behring GmbH HIBBERT, CATHERINE S 1658 §103§112DP Final Rejection Pending May 18, 2023
18035246 METHOD FOR ENZYMATIC AND/OR MICROBIAL PROCESSING OF WASTE COMPRISING RECIRCULATION OF PROCESS WATER Renescience A/S ZINGARELLI, SANDRA 1653 §103§112 Non-Final OA 66d overdue Pending May 03, 2023
18251523 Combination Treatment of Cancer Glaxosmithkline Intellectual Property (No. 4) Ltd. XIAO, YAN 1642 §103§112 Non-Final OA 8d Pending May 02, 2023
18304993 REVERSE TRANSCRIPTION OF POLYNUCLEOTIDES COMPRISING UNNATURAL NUCLEOTIDES The Scripps Research Institute FLINDERS, JEREMY C 1684 §112 Final Rejection 10d overdue Pending Apr 21, 2023
18302313 Heterocyclic Compounds as RET Kinase Inhibitors Cancer Research Technology Limited HSU, GRACE CHING 1627 §102§112Other Non-Final OA 46d overdue Pending Apr 18, 2023
18248079 CD19-Directed Chimeric Antigen Receptor Constructs Sorrento Therapeutics, Inc. HAMA, JOANNE 1647 §103§112 Final Rejection 104d overdue Pending Apr 06, 2023
18182308 CD80 VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF Alpine Immune Sciences, Inc. MOSELEY II, NELSON B 1642 DP Non-Final OA Pending Mar 10, 2023
17792976 Cytokine Prodrugs Comprising a Cleavable Linker Trutino Biosciences Inc. STOICA, ELLY GERALD 1647 §112 Final Rejection Pending Nov 07, 2022
17923208 APRIL AND BAFF INHIBITORY IMMUNOMODULATORY PROTEINS WITH AND WITHOUT A T CELL INHIBITORY PROTEIN AND METHODS OF USE THEREOF Alpine Immune Sciences, Inc. BUNNER, BRIDGET E 1647 §102§103§112DP Non-Final OA Pending Nov 03, 2022
18050333 Methods of in Vitro Cell Delivery Intellia Therapeutics, Inc. ZHU, JIANJIAN 1631 §102§103§112Other Non-Final OA 6d Pending Oct 27, 2022
17921128 Glucocorticoid Receptor (GR) Modulators for Treating a SARS-COV-2 Virus Avm Biotechnology, LLC HAVLIN, ROBERT H 1626 §103§112Other Final Rejection 23d overdue Pending Oct 25, 2022
17911808 Use of Anti-IL-6 Antibody, e.g., Clazakizumab for Treatment/Prevention of ARDS Associated with Coronavirus (COVID-19) Infection Vitaeris Inc. BUNNER, BRIDGET E 1647 §102§103§112 Non-Final OA 9d Pending Sep 15, 2022
17910415 Fetuin A for Treatment of Renal Disorders Universitaet Bern MARTINEZ, TARA L 1654 §103 Final Rejection Pending Sep 09, 2022
17905431 Barley Plants with High Limit Dextrinase Activity Carlsberg A/S MEADOWS, CHRISTINA L 1663 §103 Non-Final OA Pending Sep 01, 2022
17817777 Composition and Methods for Selective Degradation of Engineered Proteins Celgene Corporation BOWLES, DAVID PAUL 1654 §112 Non-Final OA Pending Aug 05, 2022
17845399 Pharmaceutical Composition for Treatment or Prevention of Multiple Inflammatory disorders Aardvark Therapeutics, Inc. IVANOVA, SVETLANA M 1627 §103 Non-Final OA 60d overdue Pending Jun 21, 2022
17824450 DISTANCE DOMINANT INTRAOCULAR LENS Bausch & Lomb Incorporated RIOS, GABRIELLA GISELLE BONO 3774 §103 Non-Final OA Pending May 25, 2022
17735929 Methods and Compositions for Directed Genome Editing Intellia Therapeutics, Inc. HASAN, KHALEDA B 1636 §103§112DP Non-Final OA Pending May 03, 2022
17637410 BLOOD GENE BIOMARKERS TO DIAGNOSE AND PREDICT ACUTE REJECTION IN LIVER TRANSPLANT RECIPIENTS Northwestern University MYERS, CARLA J 1682 §101§102§103§112 Non-Final OA 2d overdue Pending Feb 22, 2022
17532363 URINE BIOMARKERS Exosome Diagnostics, Inc. POHNERT, STEVEN C 1683 §101§103§112DP Final Rejection Pending Nov 22, 2021
17469665 Compositions and Methods for Treatment of Duchenne Muscular Dystrophy Vertex Pharmaceuticals Incorporated TATGE, LEXUS MARC 1600 §103DP Non-Final OA Pending Sep 08, 2021
17056103 Adoptive T-Cell Therapy for CMV Infection and CMV-Associated Diseases The Queensland Institute of Medical Research GILL, RACHEL B 1671 §103 Final Rejection Pending Jul 01, 2021
17339425 GENE-EDITING SYSTEMS FOR EDITING A CYSTIC FIBROSIS TRANSMEMBRANE REGULATOR (CFTR) GENE Vertex Pharmaceuticals Incorporated JOHNSON, ALLISON MARIE 1638 §112 Non-Final OA Pending Jun 04, 2021
16845280 GENE-EDITING SYSTEMS FOR MODIFYING A SCN9A OR SCN10A GENE AND METHODS OF USE THEREOF Vertex Pharmaceuticals Incorporated SHIN, DANA H 1635 §103 Final Rejection 49d overdue Pending Apr 10, 2020
15550951 MATERIALS AND METHODS FOR TREATMENT OF HEMOGLOBINOPATHIES William Marsh Rice University CANDELARIA, JULIANA IRENE 1600 §103DP Final Rejection Pending Aug 14, 2017

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