Prosecution Insights
Prosecution Insights
Technology area: Biotechnology & Pharmaceuticals
120 pending office actions • 25 art units • 87 examiners • 0 of 120 (0%) have an AI response strategy ready • 131 patents granted in the last 365 days
Based on the USPTO statutory response window for each pending office action. 26 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 26 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 only | 4 (3%) |
| §101 + other | 31 (26%) |
| §103 only | 26 (22%) |
| §102 only | 7 (6%) |
| §112 only | 5 (4%) |
| Double-patenting only | 2 (2%) |
| Double-patenting + other | 8 (7%) |
| Multi-statute (no §101) | 37 (31%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| CROW, ROBERT THOMAS | 6 | 41.7% | +32.7% |
| POHNERT, STEVEN C | 5 | 12.5% | +18.3% |
| RILEY, JEZIA | 3 | 83.0% | +7.3% |
| SCHULTZHAUS, JANNA NICOLE | 3 | 34.7% | +37.4% |
| WOITACH, JOSEPH T | 3 | 49.9% | +28.2% |
| YOUNG, BRIAN ELLIS | 2 | 65.8% | +24.8% |
| GZYBOWSKI, MICHAEL STANLEY | 2 | 67.6% | +52.2% |
| WILDER, CYNTHIA B | 2 | 71.0% | +26.6% |
| CHUNDURU, SURYAPRABHA | 2 | 53.3% | +17.8% |
| MUI, CHRISTINE T | 2 | 78.3% | +19.9% |
Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 3 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18650800 | CONTROLLED POLYNUCLEOTIDE TRANSLOCATION IN NANOPORE SEQUENCING | RILEY, JEZIA | — |
| 18393291 | METHODS OF SEQUENCING USING 3' BLOCKED NUCLEOTIDES | RILEY, JEZIA | — |
| 18569532 | METHODS OF DETECTING METHYLCYTOSINE AND HYDROXYMETHYLCYTOSINE BY SEQUENCING | RILEY, JEZIA | — |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17250814 | METHODS AND SYSTEMS FOR MONITORING ORGAN HEALTH AND DISEASE | BAILEY, STEVEN WILLIAM | 45d overdue |
| 18300343 | SYSTEM AND METHOD FOR SECONDARY ANALYSIS OF NUCLEOTIDE SEQUENCING DATA | LIU, GUOZHEN | 18d overdue |
| 17839387 | QUALITY SCORE CALIBRATION OF BASECALLING SYSTEMS | DARRIGRAND, EMILY ANN | 16d overdue |
| 18129565 | MACHINE LEARNING MODELING OF PROBE INTENSITY | RODEN, DONALD THOMAS | 3d overdue |
| 17805138 | SIGNAL-TO-NOISE-RATIO METRIC FOR DETERMINING NUCLEOTIDE-BASE CALLS AND BASE-CALL QUALITY | KALLAL, ROBERT JAMES | 12d |
| 17813852 | METHODS FOR PREPARING SUBSTRATE SURFACE FOR DNA SEQUENCING | RAYMONDA, MATTHEW HAROLD | 27d |
| 18156846 | LIGHT ENERGY FLUORESCENCE EXCITATION | XU, XIAOYUN | 33d |
| 18215641 | NON-CONTACT DISPENSERS AND RELATED SYSTEMS AND METHODS | LYLE, SOPHIA YUAN | 34d |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18176761 | FUNCTIONALIZED NANOSTRUCTURES AND FLOW CELL DEPRESSIONS | CROW, ROBERT THOMAS | 24d overdue |
| 17518135 | SYSTEMS AND METHODS FOR MAKING SEQUENCING LIBRARIES | YOUNG, BRIAN ELLIS | 3d overdue |
| 18069688 | INSTRUMENTS, SYSTEMS, AND METHODS FOR MEASURING LIQUID FLOW THROUGH CHANNELS | GZYBOWSKI, MICHAEL STANLEY | 12d |
| 18885481 | METHODS OF PREPARING LOOP FORK LIBRARIES | YOUNG, BRIAN ELLIS | 15d |
| 17618836 | METHODS FOR SEQUENCING POLYNUCLEOTIDES | WILDER, CYNTHIA B | 19d |
| 18467770 | NANOPARTICLE WITH POLYNUCLEOTIDE BINDING SITE AND METHOD OF MAKING THEREOF | CROW, ROBERT THOMAS | 29d |
| 18343696 | SEQUENCING NANOPARTICLES AND METHODS OF MAKING THE SAME | CROW, ROBERT THOMAS | 34d |
| 18164341 | Microfluidic Droplet Generators | CROW, ROBERT THOMAS | 34d |
| Art Unit | Apps |
|---|---|
| 1682 | 13 |
| 1683 | 12 |
| 1684 | 9 |
| 1681 | 8 |
| 1798 | 6 |
| 1686 | 5 |
| 1685 | 5 |
| 1687 | 5 |
| 2877 | 4 |
| 1796 | 4 |
| App # | Title | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|
| 18987285 | SEQUENCE DATA PROCESSING, RETENTION, AND RECOVERY | HU, JENSEN | 2169 | §102§103 | Non-Final OA | 35d | Pending | Dec 19, 2024 |
| 18939115 | AUTOFOCUS FUNCTIONALITY IN OPTICAL SAMPLE ANALYSIS | AMARA, MOHAMED K | 2877 | §102§112 | Non-Final OA | — | Pending | Nov 06, 2024 |
| 18921425 | DYNAMIC AUTOFOCUS METHOD AND SYSTEM FOR ASSAY IMAGER | BRYANT, REBECCA CAROLE | 2877 | §103§112 | Non-Final OA | — | Pending | Oct 21, 2024 |
| 18885481 | METHODS OF PREPARING LOOP FORK LIBRARIES | YOUNG, BRIAN ELLIS | 1684 | §103 | Final Rejection | 15d | Pending | Sep 13, 2024 |
| 18818453 | ARTIFICIAL INTELLIGENCE-BASED QUALITY SCORING | BHATNAGAR, ANAND P | — | §101§102 | Non-Final OA | — | Pending | Aug 28, 2024 |
| 18795995 | VALVE ASSEMBLIES AND RELATED SYSTEMS | GZYBOWSKI, MICHAEL STANLEY | 1798 | §103 | Non-Final OA | — | Pending | Aug 06, 2024 |
| 18760831 | Anodized Metal Oxide Substrates Supporting Solid Support Feature Arrays for Patterned Flowcells | WILDER, CYNTHIA B | — | §103 | Non-Final OA | — | Pending | Jul 01, 2024 |
| 18759367 | SYSTEMS AND RELATED REAGENT CARTRIDGE QUEUING METHODS | WRIGHT, PATRICIA KATHRYN | — | §103§112 | Non-Final OA | — | Pending | Jun 28, 2024 |
| 18725694 | IMAGING SYSTEMS AND RELATED SYSTEMS AND METHODS | PEREZ-GUZMAN, CARLOS GABRIEL | 2877 | §103 | Final Rejection | 60d overdue | Pending | Jun 28, 2024 |
| 18758066 | PROTECTING FULLY FUNCTIONAL NUCLEOTIDES FROM DEGRADATION | POHNERT, STEVEN C | — | §103§112 | Non-Final OA | — | Pending | Jun 28, 2024 |
| 18736835 | CAPTURING AND AMPLIFYING POLYNUCLEOTIDES, AND REUSING FLOWCELLS, USING SILICA PARTICLES | CHUNDURU, SURYAPRABHA | — | §103§112 | Non-Final OA | — | Pending | Jun 07, 2024 |
| 18737223 | METHOD FOR POLISHING A SUBSTRATE | ISHAQ, ISHAQ MOHAMED SAID | — | §103§112 | Non-Final OA | — | Pending | Jun 07, 2024 |
| 18732450 | MULTI-VALVE FLUID CARTRIDGE | MUI, CHRISTINE T | — | §102Other | Non-Final OA | — | Pending | Jun 03, 2024 |
| 18664102 | DIGITAL MICROFLUIDIC SYSTEM FOR SINGLE-CELL ISOLATION AND CHARACTERIZATION OF ANALYTES | TSUI, YUNG-SHENG M | — | §102§112DP | Non-Final OA | — | Pending | May 14, 2024 |
| 18650800 | CONTROLLED POLYNUCLEOTIDE TRANSLOCATION IN NANOPORE SEQUENCING | RILEY, JEZIA | — | §102 | Non-Final OA | — | Pending | Apr 30, 2024 |
| 18633966 | CAPTURING AND AMPLIFYING POLYNUCLEOTIDES | CHUNDURU, SURYAPRABHA | — | §102§112 | Non-Final OA | — | Pending | Apr 12, 2024 |
| 18618263 | COMPOSITIONS AND METHODS FOR NUCLEIC ACID SEQUENCING | CROW, ROBERT THOMAS | — | §103§112 | Non-Final OA | — | Pending | Mar 27, 2024 |
| 18420482 | INFERRING MICROORGANISM OF ORIGIN FOR ANTIMICROBIAL RESISTANCE MARKERS IN TARGETED METAGENOMICS | MYERS, CARLA J | 1671 | §101§112 | Non-Final OA | — | Pending | Jan 23, 2024 |
| 18403902 | MULTI-OMIC ANALYSIS IN MONODISPERSE DROPLETS | KAPUSHOC, STEPHEN THOMAS | 1683 | §102§103DP | Non-Final OA | — | Pending | Jan 04, 2024 |
| 18575265 | DNA ORIGAMI STRUCTURE AND PROTEIN NANOPORE CONSTRUCT | STAVROU, CONSTANTINA E | 1632 | §102§103 | Non-Final OA | — | Pending | Dec 28, 2023 |
| 18575242 | ANALOG CIRCUIT TO COMPENSATE BIAS OFFSET IN AMPLIFIER ARRAY | SALMON, KATHERINE D | 1682 | §102§103§112 | Non-Final OA | — | Pending | Dec 28, 2023 |
| 18393291 | METHODS OF SEQUENCING USING 3' BLOCKED NUCLEOTIDES | RILEY, JEZIA | 1681 | DP | Non-Final OA | — | Pending | Dec 21, 2023 |
| 18392826 | DETECTION OF ANALYTES USING TARGETED EPIGENETIC ASSAYS, PROXIMITY-INDUCED TAGMENTATION, STRAND INVASION, RESTRICTION, OR LIGATION | SWITZER, JULIET CAROLINE | 1682 | §112 | Non-Final OA | — | Pending | Dec 21, 2023 |
| 18390578 | PALLADIUM CATALYST COMPOSITIONS AND METHODS FOR SEQUENCING BY SYNTHESIS | BELLAH, JEFFREY LAWRENCE | 1683 | §103 | Non-Final OA | — | Pending | Dec 20, 2023 |
| 18572189 | IMAGING SYSTEMS AND RELATED METHODS | PHILLIPS, RUFUS L | 2877 | §103 | Final Rejection | 76d | Pending | Dec 20, 2023 |
| 18389877 | MULTI-SURFACE BIOLOGICAL SAMPLE IMAGING SYSTEM AND METHOD | CROW, ROBERT THOMAS | 1683 | §103§112 | Non-Final OA | — | Pending | Dec 20, 2023 |
| 18545638 | CLOUD COMPUTING ENVIRONMENT FOR BIOLOGICAL DATA | LE, THANH T | 2495 | §103§112 | Non-Final OA | — | Pending | Dec 19, 2023 |
| 18571069 | APTAMER DYNAMIC RANGE COMPRESSION AND DETECTION TECHNIQUES | PHAM, KHAI QUYNH TIEN | 1682 | §103§112 | Non-Final OA | — | Pending | Dec 15, 2023 |
| 18542447 | FLOW CELLS | KASS, BENJAMIN JOSEPH | — | §102§103§112 | Non-Final OA | — | Pending | Dec 15, 2023 |
| 18542470 | FLOW CELLS | BOWERS, NATHAN ANDREW | — | §103§112 | Non-Final OA | — | Pending | Dec 15, 2023 |
| 18538441 | Reusable Flow Cells Having Primer Binding Sites Comprising Reactive Sulfur Moieties and Methods of Using the Same, and Reagents for Use Therewith | KOVACH, KARA NICOLE | 1681 | §103DP | Non-Final OA | — | Pending | Dec 13, 2023 |
| 18538262 | ALTERED CYTIDINE DEAMINASES AND METHODS OF USE | HUTSON, RICHARD G | 1652 | §103 | Final Rejection | 53d | Pending | Dec 13, 2023 |
| 18569532 | METHODS OF DETECTING METHYLCYTOSINE AND HYDROXYMETHYLCYTOSINE BY SEQUENCING | RILEY, JEZIA | 1681 | §102 | Non-Final OA | — | Pending | Dec 12, 2023 |
| 18535492 | AUTOMATED VOLUMETRIC REAGENT DELIVERY TESTING | WHATLEY, BENJAMIN R | — | §101§102§103§112DPOther | Non-Final OA | — | Pending | Dec 11, 2023 |
| 18534113 | FLOW CELLS AND SEQUENCING KITS | JONES, CHRISTINE MICHELLE | 1682 | §103§112DP | Final Rejection | 4d overdue | Pending | Dec 08, 2023 |
| 18568756 | PERIODATE COMPOSITIONS AND METHODS FOR CHEMICAL CLEAVAGE OF SURFACE-BOUND POLYNUCLEOTIDES | MARTIN, KEVIN STEPHEN | 1681 | §112Other | Non-Final OA | — | Pending | Dec 08, 2023 |
| 18568366 | DETECTING METHYLCYTOSINE USING A MODIFIED BASE OPPOSITE TO THE METHYLCYTOSINE | SALMON, KATHERINE D | 1682 | §102§103 | Final Rejection | — | Pending | Dec 08, 2023 |
| 18567989 | ORTHOGONAL HYBRIDIZATION | PARISI, JESSICA DANIELLE | 1682 | §102§103§112 | Non-Final OA | — | Pending | Dec 07, 2023 |
| 18530865 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' BLOCKING GROUPS AND CLEAVABLE LINKERS | CRAIGO, BAHAR ALAWI | 1699 | §112 | Non-Final OA | — | Pending | Dec 06, 2023 |
| 18530025 | ETCH-FREE PHOTORESIST PATTERNING IN MULTI-DEPTH NANOWELLS | GORDON, BRIAN R | — | §102§103§112 | Non-Final OA | — | Pending | Dec 05, 2023 |
| 18566369 | IDENTIFYING NUCLEOTIDES USING CHANGES IN IMPEDANCE BETWEEN ELECTRODES | GRAY, JESSICA | 1682 | §101§103§112 | Non-Final OA | — | Pending | Dec 01, 2023 |
| 18523636 | FLOW CELLS WITH PASSIVATION COMPONENTS | ALABI, OYELEYE A | — | §102§103 | Non-Final OA | — | Pending | Nov 29, 2023 |
| 18515013 | REVERSIBLY CROSS-LINKED HYDROGELS, AND METHODS OF USING THE SAME FOR CLUSTER AMPLIFICATION | YU, TIAN NMN | 1681 | §103 | Final Rejection | — | Pending | Nov 20, 2023 |
| 18562095 | OLIGO-MODIFIED NUCLEOTIDE ANALOGUES FOR NUCLEIC ACID PREPARATION | VANHORN, ABIGAIL LOUISE | — | §102§103§112 | Non-Final OA | — | Pending | Nov 17, 2023 |
| 18507414 | DESIGNING PROBES FOR DEPLETING ABUNDANT TRANSCRIPTS | POHNERT, STEVEN C | 1683 | §101§103§112 | Non-Final OA | — | Pending | Nov 13, 2023 |
| 18484268 | DETECTING AND CORRECTING METHYLATION VALUES FROM METHYLATION SEQUENCING ASSAYS | ZEMAN, MARY K | — | §101§103 | Non-Final OA | — | Pending | Oct 10, 2023 |
| 18477346 | COPY NUMBER VARIATION (CNV) BREAKPOINT DETECTION | BICKHAM, DAWN MARIE | — | §101§102§103§112 | Non-Final OA | — | Pending | Sep 28, 2023 |
| 18476052 | METHODS OF MODULATING CLUSTERING KINETICS | JONES, CHRISTINE MICHELLE | 1682 | §101§102§103§112DPOther | Final Rejection | — | Pending | Sep 27, 2023 |
| 18476232 | MACHINE-LEARNING MODEL FOR REFINING STRUCTURAL VARIANT CALLS | LEMMA, SAMSON B | 2498 | §103 | Final Rejection | — | Pending | Sep 27, 2023 |
| 18476031 | MESOPHILIC COMPOSITIONS FOR NUCLEIC ACID AMPLIFICATION | POHNERT, STEVEN C | 1683 | §101§102§103§112DP | Non-Final OA | — | Pending | Sep 27, 2023 |
IP Author helps IP teams respond to office actions faster with AI-generated responses, examiner analytics, and prosecution intelligence.
Start Free TrialIllumina Inc. has 120 pending office actions as of October 2026, spread across 25 art units and 87 examiners.
Robert Thomas Crow has the most, with 6 of Illumina Inc.'s pending office actions.
Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.