Prosecution Insights
Prosecution Insights
Technology area: Biotechnology & Pharmaceuticals
89 pending office actions • 37 clients • 78 examiners • 41 art units • 0 of 89 (0%) have an AI response strategy ready
HOWSON & HOWSON LLP maintains a focused practice in the Biotechnology & Pharmaceuticals technology area. With 4022 career applications, the firm has extensive experience navigating the specific legal and technical hurdles of the life sciences sector. Its resolved allowance rate pct of 78.22 provides a measure of its success in obtaining patent protection for its clients. This rate reflects the firm's capability in a field known for rigorous examination standards.
The firm is currently handling 74 pending office actions, indicating a steady flow of active prosecution work. The firm averages 3.6 avg office actions per allowance, which suggests a rigorous examination process that often requires multiple responses to the patent office. This 3.6 avg office actions per allowance, combined with the 78.22 resolved allowance rate pct, characterizes the firm's persistent approach to securing grants for its 4022 career applications. For practitioners, these metrics provide a baseline for evaluating the firm's performance and the typical prosecution timeline in Biotechnology & Pharmaceuticals.
Based on the USPTO statutory response window for each pending office action. 26 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 26 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 + other | 13 (15%) |
| §103 only | 8 (9%) |
| §112 only | 12 (13%) |
| Double-patenting only | 2 (2%) |
| Double-patenting + other | 12 (13%) |
| Multi-statute (no §101) | 42 (47%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| VIVLEMORE, TRACY ANN | 4 | 73.0% | +6.6% |
| SWITZER, JULIET CAROLINE | 3 | 42.4% | +54.0% |
| KAPUSHOC, STEPHEN THOMAS | 2 | 46.5% | +53.5% |
| BARRON, SEAN C | 2 | 52.9% | +30.9% |
| SULLIVAN, STEPHANIE LAUREN | 2 | 58.1% | +40.9% |
| KONOPKA, CATHERINE ANNE | 2 | 58.1% | +65.0% |
| MYERS, CARLA J | 2 | 49.3% | +46.1% |
| SPENCER, ANDREA LYNNE MORRIS | 2 | 22.2% | +35.7% |
| MILLER, DANIEL A | 1 | 34.3% | +57.8% |
| HELM, CARALYNNE E | 1 | 28.9% | +49.6% |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17995539 | REAWAKENING OF DORMANT TUMOR CELLS BY MODIFIED LIPIDS DERIVED FROM STRESS ACTIVATED NEUTROPHILS | KONOPKA, CATHERINE ANNE | 182d overdue |
| 17601542 | The Treatment of Protein Aggregation Diseases | JOHNSON, ALLISON MARIE | 125d overdue |
| 18863982 | Hybrid Solar Panel and Photovoltaic and Thermal Roof | CANNON, RYAN SMITH | 120d overdue |
| 18042730 | COMPOSITIONS AND METHODS FOR EARLY DETECTION OF OSTEOPOROSIS | LUSI, ELLIS FOLLETT | 79d overdue |
| 18257504 | CHEMICALLY MODIFIED CRISPR-CAS13 GUIDE RNAS | KONOPKA, CATHERINE ANNE | 38d overdue |
| 17356146 | IN VIVO DETECTION OF EGFR MUTATION IN GLIOBLASTOMA VIA MRI SIGNATURE CONSISTENT WITH DEEP PERITUMORAL INFILTRATION | SCHULTZHAUS, JANNA NICOLE | 36d overdue |
| 18250459 | METHODS AND COMPOSITIONS FOR NUTRITIONAL SUSTENANCE AND WASTE SCAVENGING IN TISSUE INJURIES AND WOUNDS | AL-AWADI, DANAH J | 26d overdue |
| 18560153 | COMPOSITIONS AND METHODS FOR DEBULKING VIRUS OR MICROORGANISM LOAD IN THE ORAL CAVITY | MOAZZAMI, NAGHMEH NINA | 4d overdue |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17995539 | REAWAKENING OF DORMANT TUMOR CELLS BY MODIFIED LIPIDS DERIVED FROM STRESS ACTIVATED NEUTROPHILS | KONOPKA, CATHERINE ANNE | 182d overdue |
| 18257504 | CHEMICALLY MODIFIED CRISPR-CAS13 GUIDE RNAS | KONOPKA, CATHERINE ANNE | 38d overdue |
| 17997110 | COMPOSITIONS AND METHODS FOR REDUCING NUCLEASE EXPRESSION AND OFF-TARGET ACTIVITY USING A PROMOTER WITH LOW TRANSCRIPTIONAL ACTIVITY | SPENCER, ANDREA LYNNE MORRIS | 6d |
| 17787433 | NOVEL DRUGGABLE TARGETS FOR THE TREATMENT OF INFLAMMATORY DISEASES SUCH AS SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) AND METHODS FOR DIAGNOSIS AND TREATMENT USING THE SAME | KAPUSHOC, STEPHEN THOMAS | 56d |
| 18306548 | COMPOSITIONS AND METHODS FOR DIAGNOSING LUNG CANCERS USING GENE EXPRESSION PROFILES | SWITZER, JULIET CAROLINE | 83d |
| 19165958 | WOUND DRESSINGS WITH ADHESIVE BORDERS | MILLER, DANIEL A | — |
| 18575738 | SOLUTION FOR DESTROYING BIOFILMS AND METHOD OF PRODUCING THEREOF | HELM, CARALYNNE E | — |
| 18833257 | PHAGE MEDIATED IMMUNO-PCR FOR THE DIAGNOSIS OF ALZHEIMER'S DISEASE | KAPUSHOC, STEPHEN THOMAS | — |
| Art Unit | Apps |
|---|---|
| 1635 | 7 |
| 1682 | 6 |
| 1631 | 6 |
| 1638 | 6 |
| 1672 | 3 |
| 1674 | 3 |
| 1633 | 2 |
| 1625 | 2 |
| 1636 | 2 |
| 1637 | 2 |
| App # | Title | Client | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|---|
| 19165958 | WOUND DRESSINGS WITH ADHESIVE BORDERS | Plastod S.p.A. | MILLER, DANIEL A | 3786 | §102§103§112 | Non-Final OA | — | Pending | Sep 16, 2025 |
| 18575738 | SOLUTION FOR DESTROYING BIOFILMS AND METHOD OF PRODUCING THEREOF | Misera Co., Ltd. | HELM, CARALYNNE E | §102§112 | Non-Final OA | — | Pending | Jan 24, 2025 | |
| 18992645 | COMPOSITIONS AND USES THEREOF | Optibiotix Limited | PAK, JOHN D | §102§103§112 | Non-Final OA | — | Pending | Jan 09, 2025 | |
| 18874238 | COMBINED USE OF A PROBIOTIC AND BUTYRIC ACID TO INCREASE THE ENTEROCYTE'S HEALTH AND CONSEQUENTLY THE WELLNESS OF PETS AND LIVESTOCK | Cerbios-Pharma SA | UNDERDAHL, THANE E | §102§103DP | Non-Final OA | — | Pending | Dec 12, 2024 | |
| 18869792 | ENERGY OPTIMIZATION OF A HEAT TRANSPORT SYSTEM | Grundfos Holding A/S | LIN, JASON | §101§103§112 | Non-Final OA | — | Pending | Nov 26, 2024 | |
| 18863982 | Hybrid Solar Panel and Photovoltaic and Thermal Roof | Sic Divisione Elettronica S.R.L.U. | CANNON, RYAN SMITH | 1726 | §102§103§112 | Non-Final OA | 120d overdue | Pending | Nov 07, 2024 |
| 18925333 | PIPELINE INSPECTION SYSTEM | Catholic Kwandong University Industry Foundation | SINGER, DAVID L | §102§103 | Non-Final OA | — | Pending | Oct 24, 2024 | |
| 18854774 | JOINT LEAKAGE DETECTION SYSTEM | Integrity Engineering Solutions Pty Ltd. | PLUMB, NIGEL H | §102§103§112 | Non-Final OA | — | Pending | Oct 07, 2024 | |
| 18853162 | BIODEGRADABLE LIPIDOIDS AND COMPOSITIONS AND METHODS OF USE THEREOF FOR LIVER TARGETED DELIVERY | The Trustees of the University of Pennsylvania | TCHERKASSKAYA, OLGA V | §103§112DP | Non-Final OA | — | Pending | Oct 01, 2024 | |
| 18820706 | FASORACETAM CRYSTALLINE FORMS | The Children's Hospital of Philadelphia | AULAKH, CHARANJIT | §102§103§112DP | Non-Final OA | — | Pending | Aug 30, 2024 | |
| 18833257 | PHAGE MEDIATED IMMUNO-PCR FOR THE DIAGNOSIS OF ALZHEIMER'S DISEASE | Universita’ Degli Studi Di Messina | KAPUSHOC, STEPHEN THOMAS | §101§102§112 | Non-Final OA | — | Pending | Jul 25, 2024 | |
| 18779936 | METHOD AND DEVICE FOR WASHING/CLEANING GRANULAR MATERIAL FROM SLAG AND WASHING/CLEANING BOTTOM/BOILER ASH FROM A THERMAL WASTE TREATMENT, AND MINERAL RESIDUE AND RECYCLING MATERIAL | H-U-R Hamburg GmbH Hamburger-Umwelt-Recyclingtechnologien | AYALEW, TINSAE B | 1711 | §103 | Final Rejection | 23d | Pending | Jul 22, 2024 |
| 18770804 | SAFETY QUICK-REFILL COMPACT PUMP FOR ADMINISTERING DRUGS | Cane' S.p.A. | BOUCHELLE, LAURA A | §103§112Other | Non-Final OA | — | Pending | Jul 12, 2024 | |
| 18727953 | COMPOSITIONS USEFUL IN TREATMENT OF METACHROMATIC LEUKODYSTROPHY | The Trustees of the University of Pennsylvania | WILSON, MICHAEL C | §102§112Other | Non-Final OA | — | Pending | Jul 10, 2024 | |
| 18737396 | SEQUENTIAL APPLICATION OF MACROPHAGES FOR WOUND HEALING | Drexel University | NICOL, ALEXANDER W | §103 | Non-Final OA | — | Pending | Jun 07, 2024 | |
| 18713342 | FLAVANOID CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF FOR THE TREATMENT OF MITOCHONDRIAL DISORDERS | The Children's Hospital of Philadelphia | OLSON, ANDREA STEFFEL | §101§102§103§112DP | Non-Final OA | — | Pending | May 24, 2024 | |
| 18712323 | COMPOSITIONS AND METHODS FOR TREATMENT OF FABRY DISEASE | The Trustees of the University of Pennsylvania | BARRON, SEAN C | §103 | Non-Final OA | — | Pending | May 22, 2024 | |
| 18709415 | GENE THERAPY FOR TREATMENT OF MUCOPOLYSACCHARIDOSIS IIIA | The Trustees of the University of Pennsylvania | ALLEN, SARAH ELIZABETH | §102§103§112Other | Non-Final OA | — | Pending | May 10, 2024 | |
| 18702258 | COMPOSITIONS USEFUL IN TREATMENT OF CDKL5 DEFICIENCY DISORDER (CDD) | The Trustees of the University of Pennsylvania | SINGH, ANOOP KUMAR | §112DP | Non-Final OA | — | Pending | Apr 17, 2024 | |
| 18700437 | METHODS FOR INCREASING FAT ABSORPTION | Structured Lipid Nutrition, LLC | SZNAIDMAN, MARCOS L | 1628 | §102§103 | Non-Final OA | — | Pending | Apr 11, 2024 |
| 18698524 | COMPOSITIONS AND METHODS OF AMELIORATING AVERSIVENESS OF AVERSIVE STIMULI BY INHIBITION OF PURINERGIC RECEPTORS | Paul Breslin | CHICKS, ASHLI ARIANA | 1626 | §103§112 | Non-Final OA | — | Pending | Apr 04, 2024 |
| 18687571 | METHODS FOR EVALUATING TREATMENTS FOR BESTROPHINOPATHIES | The Trustees of the University of Pennsylvania | BARRON, SEAN C | 1653 | §101§103 | Non-Final OA | — | Pending | Feb 28, 2024 |
| 18578997 | MODIFIED ADAPTERS FOR ENZYMATIC DNA DEAMINATION AND METHODS OF USE THEREOF FOR EPIGENETIC SEQUENCING OF FREE AND IMMOBILIZED DNA | The Trustees of the University of Pennsylvania | CASH, KAILEY ELIZABETH | 1682 | §103§112DP | Non-Final OA | — | Pending | Jan 12, 2024 |
| 18570181 | AUTOMATED SYSTEM FOR CARRYING OUT CAPPING TESTS | Arol S.p.A. | PARCO JR, RUBEN C | 2853 | §112 | Final Rejection | 56d | Pending | Dec 14, 2023 |
| 18567629 | RECOMBINANT ADENO-ASSOCIATED VIRUSES FOR LESCH-NYHAN DISORDERS AND USES THEREOF | The Trustees of the University of Pennsylvania | GOMEZ RODRIGUEZ, JULIO WASHINGTON | §103§112 | Non-Final OA | — | Pending | Dec 06, 2023 | |
| 18567168 | VESSEL PROVIDED WITH AN IMPROVED AIR CIRCULATION SYSTEM | 3J Marine S.r.l. | BURGESS, MARC R | 3615 | §102§103§112 | Non-Final OA | 22d | Pending | Dec 05, 2023 |
| 18519972 | METHODS AND COMPOSITIONS FOR TREATING METASTATIC BREAST CANCER AND OTHER CANCERS IN THE BRAIN | The Trustees of the University of Pennsylvania | ARON, KIMBERLY A | 1633 | DP | Non-Final OA | — | Pending | Nov 27, 2023 |
| 18513571 | FILTER MESH | Markert Filtration GmbH | MENDOZA, WILSON GALLARDO | 1772 | §103§112 | Non-Final OA | 46d | Pending | Nov 19, 2023 |
| 18562293 | SPUTTERING TARGET AND METHOD FOR MANUFACTURING SAME | JX Metals Corporation | OTT, PATRICK S | 1794 | §103 | Final Rejection | — | Pending | Nov 18, 2023 |
| 18560153 | COMPOSITIONS AND METHODS FOR DEBULKING VIRUS OR MICROORGANISM LOAD IN THE ORAL CAVITY | The Trustees of the University of Pennsylvania | MOAZZAMI, NAGHMEH NINA | 1652 | §103§112Other | Final Rejection | 4d overdue | Pending | Nov 10, 2023 |
| 18497386 | METHODS OF DIAGNOSING AND TREATING CONDUCT DISORDER | The Children's Hospital of Philadelphia | KOSAR, ANDREW D | 1625 | §103§112 | Non-Final OA | — | Pending | Oct 30, 2023 |
| 18557834 | COMPOSITIONS AND METHODS OF TREATING SEPSIS IN PATIENTS USING ANTI-LIGHT ANTIBODIES | The Trustees of the University of Pennsylvania | SCHWECHTER, BRANDON ROSS | 1798 | §102§112 | Non-Final OA | — | Pending | Oct 27, 2023 |
| 18556944 | COMPOSITIONS AND METHODS FOR IN VIVO NUCLEASE-MEDIATED GENE TARGETING FOR THE TREATMENT OF GENETIC DISORDERS | The Trustees of the University of Pennsylvania | SULLIVAN, STEPHANIE LAUREN | 1635 | §103§112DP | Non-Final OA | — | Pending | Oct 24, 2023 |
| 18556668 | COMPOSITIONS AND METHODS FOR PREVENTING RSV AND PIV3 INFECTIONS | UNIVERSITY OF SASKATCHEWAN | CHEN, STACY BROWN | 1672 | §112 | Non-Final OA | — | Pending | Oct 21, 2023 |
| 18287150 | COMPOSITIONS AND METHODS USEFUL FOR THE TREATMENT OF H-ABC LEUKODYSTROPHY | The Children's Hospital of Philadelphia | HUDSON, AMY ROSE | 1636 | §102§103§112 | Non-Final OA | — | Pending | Oct 16, 2023 |
| 18487647 | Foetal Monitoring System | Vitaltrace Pty Ltd. | GUERRERO ROSARIO, ANA VERUSKA | 3794 | §103§112 | Non-Final OA | — | Pending | Oct 16, 2023 |
| 18555189 | ANTI-FIBROBLAST ACTIVATION PROTEIN ANTIBODIES | Philogen S.P.A | BERHANE, SELAM | 1675 | §112 | Non-Final OA | — | Pending | Oct 12, 2023 |
| 18554748 | COMPOSITIONS USEFUL FOR TREATING SPINAL AND BULBAR MUSCULAR ATROPHY (SBMA) | The Trustees of the University of Pennsylvania | SHIBUYA, MARK LANCE | 1631 | §103§112Other | Non-Final OA | — | Pending | Oct 10, 2023 |
| 18546321 | Composition and Use Thereof | Axisbiotix Limited | DEVI, SARVAMANGALA | 1645 | §112 | Final Rejection | — | Pending | Aug 14, 2023 |
| 18264885 | COMPOSITIONS AND METHODS FOR TREATING PULMONARY ARTERIAL HYPERTENSION (PAH) AND OTHER DISORDERS | The Trustees of the University of Pennsylvania | LIPPOLIS, ALEXANDRA ROSE | 1637 | §102§103§112 | Non-Final OA | — | Pending | Aug 09, 2023 |
| 17906173 | TARGETED DELIVERY OF EXTRACELLULAR VESICLES | Evox Therapeutics Ltd. | HAMA, JOANNE | 1647 | §103§112 | Final Rejection | 71d | Pending | Jul 27, 2023 |
| 18263085 | COMPOSITIONS AND METHODS FOR TREATMENT OF NIEMANN PICK TYPE A DISEASE | The Trustees of the University of Pennsylvania | TATGE, LEXUS MARC | 1637 | §102§103§112 | Non-Final OA | — | Pending | Jul 26, 2023 |
| 18260786 | COMPOSITIONS FOR TREATING FRIEDREICH'S ATAXIA | The Trustees of the University of Pennsylvania | MIANO, JOSEPH PAUL | 1631 | §103DP | Final Rejection | 27d | Pending | Jul 09, 2023 |
| 18259964 | PHARMACEUTICAL COMPOSITION FOR INHALATION | Shanghai Huilun Jiangsu Pharmaceutical Co., Ltd. | RAMOS LEWIS, JOSMALEN MILAGROS | 1621 | §103§112 | Final Rejection | — | Pending | Jun 29, 2023 |
| 18257504 | CHEMICALLY MODIFIED CRISPR-CAS13 GUIDE RNAS | New York University | KONOPKA, CATHERINE ANNE | 1635 | §102§103§112Other | Final Rejection | 38d overdue | Pending | Jun 14, 2023 |
| 18041627 | Methods and Compositions for Inhibiting Viral Infection | New York University | OH, TAYLOR V | 1625 | §102§103§112 | Non-Final OA | — | Pending | Jun 02, 2023 |
| 18252115 | COMPOSITIONS AND METHODS FOR PREDICTING RISK OF MODERATE TO SEVERE COVID-19 DISEASE | The Wistar Institute | ALAM, DANYAL HASSAN | 1672 | §101§102§103§112 | Final Rejection | — | Pending | May 08, 2023 |
| 18250471 | VIRAL VECTORS ENCODING CANINE INSULIN FOR TREATMENT OF METABOLIC DISEASES IN DOGS | The Trustees of the University of Pennsylvania | LI, BAO Q | 1654 | §102§103§112 | Non-Final OA | — | Pending | Apr 25, 2023 |
| 18306548 | COMPOSITIONS AND METHODS FOR DIAGNOSING LUNG CANCERS USING GENE EXPRESSION PROFILES | The Wistar Institute | SWITZER, JULIET CAROLINE | 1682 | §101§102§103§112Other | Non-Final OA | 83d | Pending | Apr 25, 2023 |
| 18250459 | METHODS AND COMPOSITIONS FOR NUTRITIONAL SUSTENANCE AND WASTE SCAVENGING IN TISSUE INJURIES AND WOUNDS | New York Society for the Relief of the Ruptured and Crippled, Maintaining the Hospital for Special | AL-AWADI, DANAH J | 1615 | §102§103§112 | Non-Final OA | 26d overdue | Pending | Apr 25, 2023 |
| 18249591 | BORONIC ESTERS AND COATINGS COMPRISING THEM | Petroliam Nasional Berhad (Petronas) | BUTCHER, ROBERT T | 1764 | §103 | Non-Final OA | — | Pending | Apr 19, 2023 |
| 18246872 | COMPOSITIONS AND METHODS FOR TREATMENT OF FABRY DISEASE | The Trustees of the University of Pennsylvania | VIJAYARAGHAVAN, JAGAMYA NMN | 1633 | §103§112DP | Final Rejection | 73d overdue | Pending | Mar 28, 2023 |
| 18246604 | METHODS AND COMPOSITIONS FOR IN SITU IMMUNE PROFILING OF HEART TRANSPLANT BIOPSIES | The Trustees of the University of Pennsylvania | CARTER, SANDRA DILLAHUNT | 1674 | §101§112 | Non-Final OA | — | Pending | Mar 24, 2023 |
| 18044471 | GENETIC ALTERATIONS ASSOCIATED WITH EOSINOPHILIC ESOPHAGITIS AND METHODS OF USE THEREOF FOR THE DIAGNOSIS AND TREATMENT OF DISEASE | The Children's Hospital of Philadelphia | MYERS, CARLA J | 1682 | §112 | Non-Final OA | — | Pending | Mar 08, 2023 |
| 18042730 | COMPOSITIONS AND METHODS FOR EARLY DETECTION OF OSTEOPOROSIS | New York Society for the Relief of the Ruptured and Crippled, Maintaining the Hospital for Special | LUSI, ELLIS FOLLETT | 1677 | §101§112 | Non-Final OA | 79d overdue | Pending | Feb 23, 2023 |
| 18042726 | VIRAL VECTORS ENCODING GLP-1 RECEPTOR AGONIST FUSIONS AND USES THEREOF IN TREATING METABOLIC DISEASES | The Trustees of the University of Pennsylvania | HUMPHRIES, NICHOLAS ADAM | 1631 | §103DP | Final Rejection | — | Pending | Feb 23, 2023 |
| 18040971 | RECOMBINANT ADENO-ASSOCIATED VIRUS FOR TREATMENT OF GRN-ASSOCIATED ADULT-ONSET NEURODEGENERATION | The Trustees of the University of Pennsylvania | THUESON, HANNA MARIE | 1638 | §103 | Final Rejection | 74d overdue | Pending | Feb 07, 2023 |
| 18040648 | NOVEL AAV CAPSIDS AND COMPOSITIONS CONTAINING SAME | The Trustees of the University of Pennsylvania | SPENCER, ANDREA LYNNE MORRIS | 1631 | §102§103§112DPOther | Non-Final OA | — | Pending | Feb 05, 2023 |
| 18006975 | IN UTERO AND POSTNATAL GENE EDITING AND THERAPY FOR TREATMENT OF MONOGENIC DISEASES, INCLUDING MUCOPOLYSACCHARIDOSIS TYPE 1H AND OTHER DISORDERS | The Children's Hospital of Philadelphia | MCLEOD, AFRICA MHAIRIE | 1635 | §102§103§112 | Non-Final OA | — | Pending | Jan 26, 2023 |
| 18004618 | COMPOSITIONS COMPRISING ANTIBODIES TO HUMAN IDO-2 | Lankenau Institute For Medical Research | STONEBRAKER, ALYSSA RAE | 1642 | §112 | Final Rejection | 8d overdue | Pending | Jan 06, 2023 |
| 18061633 | GENE THERAPY FOR OCULAR DISORDERS | The Trustees of the University of Pennsylvania | VIVLEMORE, TRACY ANN | 1638 | §103§112 | Non-Final OA | — | Pending | Dec 05, 2022 |
| 18000010 | METHODS AND COMPOSITIONS FOR TREATING, PREVENTING THE ONSET AND/OR SLOWING PROGRESSION OF OSTEOARTHRITIS | New York Society for the Relief of the Ruptured and Crippled, Maintaining the Hospital for Special | LI, RUIXIANG | 1674 | §112 | Final Rejection | 7d | Pending | Nov 28, 2022 |
| 18057359 | EXOSOMES COMPRISING THERAPEUTIC POLYPEPTIDES | Oxford University Innovation Limited | HASAN, KHALEDA B | 1636 | §103§112 | Non-Final OA | — | Pending | Nov 21, 2022 |
| 17998330 | COMPOSITIONS USEFUL IN TREATMENT OF KRABBE DISEASE | The Trustees of the University of Pennsylvania | RIGA, MICHAEL ANGELO | 1634 | §103§112 | Non-Final OA | 34d | Pending | Nov 09, 2022 |
| 17922196 | Method, System and Apparatus for Investigating or Assessing Eye or Pupil Movement | Neurotologix Pty Ltd. | WESTFALL, SARAH ANN | 3791 | §101§102§103§112 | Final Rejection | — | Pending | Oct 28, 2022 |
| 17997110 | COMPOSITIONS AND METHODS FOR REDUCING NUCLEASE EXPRESSION AND OFF-TARGET ACTIVITY USING A PROMOTER WITH LOW TRANSCRIPTIONAL ACTIVITY | The Trustees of the University of Pennsylvania | SPENCER, ANDREA LYNNE MORRIS | 1631 | §103§112Other | Non-Final OA | 6d | Pending | Oct 25, 2022 |
| 17997004 | COMPOSITIONS AND USES THEREOF FOR TREATMENT OF ANGELMAN SYNDROME | The Trustees of the University of Pennsylvania | BRETZ, COREY LANE | 1635 | §103§112 | Final Rejection | — | Pending | Oct 24, 2022 |
| 17996379 | LIPOSOMAL COMPOSITION FOR PREVENTING OR EARLY TREATMENT OF PATHOGENIC INFECTION | Statens Serum Institut | BROWE, DAVID | 1617 | §112 | Non-Final OA | — | Pending | Oct 17, 2022 |
| 17995539 | REAWAKENING OF DORMANT TUMOR CELLS BY MODIFIED LIPIDS DERIVED FROM STRESS ACTIVATED NEUTROPHILS | The Wistar Institute | KONOPKA, CATHERINE ANNE | 1635 | §102§103§112 | Non-Final OA | 182d overdue | Pending | Oct 05, 2022 |
| 17904903 | TREATING AUTOSOMAL RECESSIVE BESTROPHINOPATHIES AND METHODS FOR EVALUATING SAME | The Trustees of the University of Pennsylvania | VIVLEMORE, TRACY ANN | 1638 | §102§112Other | Final Rejection | — | Pending | Aug 24, 2022 |
| 17904899 | TREATING AUTOSOMAL DOMINANT BESTROPHINOPATHIES AND METHODS FOR EVALUATING SAME | The Trustees of the University of Pennsylvania | VIVLEMORE, TRACY ANN | 1638 | §102§112DP | Final Rejection | — | Pending | Aug 24, 2022 |
| 17867335 | COMPOSITIONS AND METHODS FOR GENERATION OF RETINAL GANGLION CELLS FROM INDUCIBLE PLURIPOTENT STEM CELLS FOR THE TREATMENT OF PROGRESSIVE OPTIC NEUROPATHIES, INCLUDING GLAUCOMA | The Trustees of the University of Pennsylvania | STAVROU, CONSTANTINA E | 1632 | §102§103 | Non-Final OA | — | Pending | Jul 18, 2022 |
| 17787433 | NOVEL DRUGGABLE TARGETS FOR THE TREATMENT OF INFLAMMATORY DISEASES SUCH AS SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) AND METHODS FOR DIAGNOSIS AND TREATMENT USING THE SAME | The Children's Hospital of Philadelphia | KAPUSHOC, STEPHEN THOMAS | 1683 | §112 | Non-Final OA | 56d | Pending | Jun 20, 2022 |
| 17761027 | STABILIZED C-FMS INTRACELLULAR FRAGMENTS (FICD) PROMOTE OSTEOCLAST DIFFERENTIATION AND ARTHRITIC BONE EROSION | New York Society for the Relief of the Ruptured and Crippled, Maintaining the Hospital for Special | CHEN, PO-CHIH | 1621 | §102§112 | Non-Final OA | — | Pending | Mar 16, 2022 |
| 17641502 | COMPOSITIONS COMPRISING RARE GENETIC SEQUENCE VARIANTS ASSOCIATED WITH PULMONARY FUNCTION AND METHODS OF USE THEREOF FOR DIAGNOSIS AND TREATMENT OF ASTHMA IN AFRICAN AMERICAN PATIENTS | The Children's Hospital of Philadelphia | MYERS, CARLA J | 1682 | §112 | Non-Final OA | — | Pending | Mar 09, 2022 |
| 17641650 | NOVEL GENETIC MARKERS FOR POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (POTS) AND METHODS OF USE THEREOF FOR DIAGNOSIS AND TREATMENT OF THE SAME | The Children's Hospital of Philadelphia | SWITZER, JULIET CAROLINE | 1682 | §101§102§103§112 | Non-Final OA | — | Pending | Mar 09, 2022 |
| 17672438 | COMPOSITIONS AND METHODS FOR INHIBITING BIOFILM DEPOSITION AND PRODUCTION | The Trustees of the University of Pennsylvania | DABKOWSKI, ERINNE R | 1654 | DP | Non-Final OA | — | Pending | Feb 15, 2022 |
| 17634968 | NOVEL LOX-1 ANTIBODY COMPOSITIONS, LOX1 NEUTRALIZATION ASSAY AND METHODS OF TREATMENT USING SAME | The Wistar Institute | SHUPE, ELIZABETH A | 1643 | §112 | Non-Final OA | 162d overdue | Pending | Feb 12, 2022 |
| 17523492 | Methods and Compositions for Treatment of Disorders and Diseases Involving RDH12 | The Trustees of the University of Pennsylvania | YU, DAVID TUYANG | 1635 | §102§103§112 | Final Rejection | — | Pending | Nov 10, 2021 |
| 17601542 | The Treatment of Protein Aggregation Diseases | Pharmakure Limited | JOHNSON, ALLISON MARIE | 1638 | §101§102§112 | Non-Final OA | 125d overdue | Pending | Oct 05, 2021 |
| 17601581 | COMPOSITIONS AND METHODS FOR IN UTERO GENE EDITING FOR MONOGENIC LUNG DISEASE | The Trustees of the University of Pennsylvania | BATES, KEENAN ALEXANDER | 1631 | §103§112 | Final Rejection | 5d | Pending | Oct 05, 2021 |
| 17424363 | MICROCATHETER FOR THERAPEUTIC AND/OR DIAGNOSTIC INTERVENTIONS IN THE SUBARACHNOID SPACE | The Trustees of the University of Pennsylvania | LUU, TIMOTHY TUAN | 3795 | §103§112 | Non-Final OA | — | Pending | Jul 20, 2021 |
| 17356146 | IN VIVO DETECTION OF EGFR MUTATION IN GLIOBLASTOMA VIA MRI SIGNATURE CONSISTENT WITH DEEP PERITUMORAL INFILTRATION | The Trustees of the University of Pennsylvania | SCHULTZHAUS, JANNA NICOLE | 1685 | §101§103§112 | Non-Final OA | 36d overdue | Pending | Jun 23, 2021 |
| 17336180 | BIOMARKERS FOR PREDICTING RISK OF ACUTE ISCHEMIC STROKE AND METHODS OF USE THEREOF | The University of North Carolina at Chapel Hill | SWITZER, JULIET CAROLINE | 1682 | §101§103§112 | Final Rejection | — | Pending | Jun 01, 2021 |
| 17279542 | 2' FANA MODIFIED FOXP3 ANTISENSE OLIGONUCLEOTIDES AND METHODS OF USE THEREOF | The Children's Hospital of Philadelphia | SULLIVAN, STEPHANIE LAUREN | 1635 | §103§112 | Non-Final OA | — | Pending | Mar 24, 2021 |
| 17097997 | COMPOSITIONS FOR DRG-SPECIFIC REDUCTION OF TRANSGENE EXPRESSION | The Trustees of the University of Pennsylvania | VIVLEMORE, TRACY ANN | 1638 | §102§112DP | Non-Final OA | — | Pending | Nov 13, 2020 |
| 17044954 | Prebiotic Compositions And Methods Of Production Thereof | Optibiotix Limited | MORNHINWEG, JEFFREY P | 1793 | §103 | Final Rejection | 33d | Pending | Oct 02, 2020 |
| 16975541 | NOVEL ADENO-ASSOCIATED VIRUS (AAV) VECTORS, AAV VECTORS HAVING REDUCED CAPSID DEAMIDATION AND USES THEREFOR | The Trustees of the University of Pennsylvania | WANG, RUIXUE | 1672 | §103 | Final Rejection | — | Pending | Aug 25, 2020 |
| 16943947 | Methods for Monitoring Polymorphonuclear Myeloid Derived Suppressor Cells and Compositions and Methods of Treatment of Cancer | The Wistar Institute | FORD, VANESSA L | 1674 | §112 | Final Rejection | 6d | Pending | Jul 30, 2020 |
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