Prosecution Insights
Prosecution Insights
Technology area: Biotechnology & Pharmaceuticals
124 pending office actions • 55 art units • 113 examiners • 0 of 124 (0%) have an AI response strategy ready • 97 patents granted in the last 365 days
The Trustees of the University of Pennsylvania manage a portfolio of 126 pending office actions within the Biotechnology & Pharmaceuticals technology area. These actions are distributed among 115 distinct examiners and 56 distinct art units. TRACY ANN VIVLEMORE is the busiest examiner for the university, currently handling 4 pending actions. The 56 distinct art units reflect the diverse nature of the university's research and patenting activities in the biotech and pharmaceutical sectors.
With 115 distinct examiners involved, the university's prosecution strategy involves navigating an array of individual examiner preferences and specialized unit practices. Despite the total of 126 pending office actions, the busiest examiner only manages 4, indicating that the workload is dispersed across the USPTO. This distribution suggests that the university's patent applications are not concentrated in a single niche but span many different scientific disciplines. With 126 pending office actions, the university is an active participant in the patent acquisition process. The involvement of a large group of examiners ensures that the university's innovations are being reviewed by a wide range of technical experts.
Based on the USPTO statutory response window for each pending office action. 38 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 38 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 + other | 13 (10%) |
| §103 only | 22 (18%) |
| §102 only | 3 (2%) |
| §112 only | 7 (6%) |
| Double-patenting only | 4 (3%) |
| Double-patenting + other | 17 (14%) |
| Multi-statute (no §101) | 57 (46%) |
| No statute on record | 1 (1%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| VIVLEMORE, TRACY ANN | 4 | 73.0% | +6.6% |
| BARRON, SEAN C | 2 | 52.9% | +30.9% |
| REDDIG, PETER J | 2 | 57.9% | +40.2% |
| SULLIVAN, STEPHANIE LAUREN | 2 | 58.1% | +40.9% |
| PERSONS, JENNA L | 2 | 50.8% | +61.7% |
| CARTER, SANDRA DILLAHUNT | 2 | 56.2% | +29.0% |
| SPENCER, ANDREA LYNNE MORRIS | 2 | 22.2% | +35.7% |
| BATES, KEENAN ALEXANDER | 2 | 45.5% | +79.5% |
| CONNORS, ALEXANDRA F | 2 | 23.9% | +45.4% |
| HOANG, HAN DINH | 1 | 75.0% | +17.7% |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 16435257 | TREATMENT OF CANCER USING ANTI-CD19 CHIMERIC ANTIGEN RECEPTOR | BRISTOL, LYNN ANNE | 132d overdue |
| 17905129 | METHODS OF USING A MULTI-ANALYTE APPROACH FOR DIAGNOSIS AND STAGING A DISEASE | HANEY, AMANDA MARIE | 77d overdue |
| 17627260 | DEVICES AND METHODS FOR RAPID SCREENING OF DRUGS OF ABUSE AND OTHER ANALYTES | SVEIVEN, MICHAEL CAMERON | 51d overdue |
| 18563707 | MONITORING OF UPPER LIMB MOVEMENTS TO DETECT STROKE | TOTH, KAREN E | 38d overdue |
| 16317943 | TREATMENT AND PREVENTION OF CYTOKINE RELEASE SYNDROME USING A CHIMERIC ANTIGEN RECEPTOR IN COMBINATION WITH A KINASE INHIBITOR | LU, CHENG | 38d overdue |
| 17356146 | IN VIVO DETECTION OF EGFR MUTATION IN GLIOBLASTOMA VIA MRI SIGNATURE CONSISTENT WITH DEEP PERITUMORAL INFILTRATION | SCHULTZHAUS, JANNA NICOLE | 36d overdue |
| 18625699 | METHODS FOR USING ENRICHED EXOSOMES AS A PLATFORM FOR MONITORING ORGAN STATUS | JUEDES, AMY E | 29d overdue |
| 17786147 | COMPOSITIONS AND METHODS FOR HEMOGLOBIN PRODUCTION | PERSONS, JENNA L | 16d overdue |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17786147 | COMPOSITIONS AND METHODS FOR HEMOGLOBIN PRODUCTION | PERSONS, JENNA L | 16d overdue |
| 17601581 | COMPOSITIONS AND METHODS FOR IN UTERO GENE EDITING FOR MONOGENIC LUNG DISEASE | BATES, KEENAN ALEXANDER | 5d |
| 17997110 | COMPOSITIONS AND METHODS FOR REDUCING NUCLEASE EXPRESSION AND OFF-TARGET ACTIVITY USING A PROMOTER WITH LOW TRANSCRIPTIONAL ACTIVITY | SPENCER, ANDREA LYNNE MORRIS | 6d |
| 17607837 | MICRO-RNA SITE BLOCKING OLIGONUCLEOTIDES FOR THE TREATMENT OF EPILEPTIC ENCEPHALOPATHY AND NEURODEVELOPMENTAL DISORDERS | SULLIVAN, STEPHANIE LAUREN | 6d |
| 18339565 | CD20 THERAPIES, CD22 THERAPIES, AND COMBINATION THERAPIES WITH A CD19 CHIMERIC ANTIGEN RECEPTOR (CAR)-EXPRESSING CELL | REDDIG, PETER J | 55d |
| 19059620 | METHODS AND APPARATUS FOR DEEP LEARNING BASED ATTENUATION CORRECTION FOR IMAGE RECONSTRUCTION | HOANG, HAN DINH | — |
| 18712323 | COMPOSITIONS AND METHODS FOR TREATMENT OF FABRY DISEASE | BARRON, SEAN C | — |
| 18687571 | METHODS FOR EVALUATING TREATMENTS FOR BESTROPHINOPATHIES | BARRON, SEAN C | — |
| Art Unit | Apps |
|---|---|
| 1631 | 7 |
| 1637 | 6 |
| 1633 | 5 |
| 1638 | 5 |
| 1632 | 4 |
| 1646 | 4 |
| 1634 | 4 |
| 1635 | 4 |
| 1678 | 3 |
| 3791 | 3 |
| App # | Title | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|
| 19059620 | METHODS AND APPARATUS FOR DEEP LEARNING BASED ATTENUATION CORRECTION FOR IMAGE RECONSTRUCTION | HOANG, HAN DINH | 2661 | §103 | Non-Final OA | — | Pending | Feb 21, 2025 |
| 18949254 | INTRAVASCULAR CERVICAL SYMPATHETIC NERVE STIMULATION SYSTEM | JIAN, SHIRLEY XUEYING | — | §102§103 | Non-Final OA | — | Pending | Nov 15, 2024 |
| 18856855 | BIODEGRADABLE LIPIDOIDS AND COMPOSITIONS AND METHODS OF USE THEREOF FOR TARGETED DELIVERY | DAVIS, BRIAN J | — | §102§112 | Non-Final OA | — | Pending | Oct 14, 2024 |
| 18904575 | Compositions and Methods for Targeting Lipid Nanoparticle Therapeutics to Stem Cells | WESTERBERG, NISSA M | 1618 | §103DP | Final Rejection | 18d overdue | Pending | Oct 02, 2024 |
| 18853162 | BIODEGRADABLE LIPIDOIDS AND COMPOSITIONS AND METHODS OF USE THEREOF FOR LIVER TARGETED DELIVERY | TCHERKASSKAYA, OLGA V | — | §103§112DP | Non-Final OA | — | Pending | Oct 01, 2024 |
| 18849467 | DEEP LEARNING SUPER RESOLUTION OF MEDICAL IMAGES | RHIM, WOO CHUL | 2676 | §103 | Non-Final OA | — | Pending | Sep 20, 2024 |
| 18846153 | METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR ASSESSING VISUAL FUNCTION USING VIRTUAL MOBILITY TESTS | SRIDHAR, SAMANVITHA | — | §102§103§112 | Non-Final OA | — | Pending | Sep 11, 2024 |
| 18822614 | PUPILLOMETER | LIU, CHU CHUAN | — | §101§103§112 | Non-Final OA | — | Pending | Sep 03, 2024 |
| 18832191 | VERSATILE ADHESION-BASED GRIPPING VIA AN UNSTRUCTURED VARIABLE STIFFNESS MEMBRANE | QURESHI, REHMAN AHMED | — | §102§103 | Non-Final OA | — | Pending | Jul 23, 2024 |
| 18771929 | NATURAL AND ARTIFICIAL INTELLIGENCE FOR ROBUST AUTOMATIC ANATOMY SEGMENTATION | LEMIEUX, IAN L | 2669 | §101§102 | Non-Final OA | — | Pending | Jul 12, 2024 |
| 18727953 | COMPOSITIONS USEFUL IN TREATMENT OF METACHROMATIC LEUKODYSTROPHY | WILSON, MICHAEL C | — | §102§112Other | Non-Final OA | — | Pending | Jul 10, 2024 |
| 18750780 | ANTI-CAR COMPOSITIONS AND METHODS | BOESEN, AGNIESZKA | — | §102§103 | Non-Final OA | — | Pending | Jun 21, 2024 |
| 18721210 | METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR CAUSAL TRAINING OF PHYSICS-INFORMED NEURAL NETWORKS | GORMLEY, AARON PATRICK | — | §102§103 | Non-Final OA | — | Pending | Jun 18, 2024 |
| 18720823 | COMPUTER-IMPLEMENTED METHODS AND ASSOCIATED SYSTEMS FOR DETECTING MALIGNANCY | JACOB, OOMMEN | 3797 | §112 | Non-Final OA | 33d | Pending | Jun 17, 2024 |
| 18716088 | ANISAMIDE-CONTAINING LIPIDS AND COMPOSITIONS AND METHODS OF USE THEREOF | SONG, JIANFENG | 1613 | §112 | Final Rejection | — | Pending | Jun 03, 2024 |
| 18675268 | Scalable, Printable, Patterned Sheet Of High Mobility Graphene On Flexible Substrates | MIGGINS, MICHAEL C | 1782 | §102§103DPOther | Final Rejection | 70d | Pending | May 28, 2024 |
| 18712323 | COMPOSITIONS AND METHODS FOR TREATMENT OF FABRY DISEASE | BARRON, SEAN C | — | §103 | Non-Final OA | — | Pending | May 22, 2024 |
| 18670290 | COMPOSITIONS AND METHODS FOR TREATING B-LYMPHOID MALIGNANCIES | LEONARD, ARTHUR S | — | §102§103§112DP | Non-Final OA | — | Pending | May 21, 2024 |
| 18668785 | ROBOTIC MICROCAPSULE ASSEMBLIES WITH EMERGENT MOBILITY FOR TARGETED TREATMENT AND DRUG DELIVERY | YANG, YI-SHAN | 1616 | §103§112 | Non-Final OA | — | Pending | May 20, 2024 |
| 18661538 | COMPOSITIONS FOR AND METHODS OF TREATING AND/OR PREVENTING MALARIA | DUFFY, PATRICIA ANN | 1645 | §101§102§112 | Non-Final OA | — | Pending | May 10, 2024 |
| 18709415 | GENE THERAPY FOR TREATMENT OF MUCOPOLYSACCHARIDOSIS IIIA | ALLEN, SARAH ELIZABETH | — | §102§103§112Other | Non-Final OA | — | Pending | May 10, 2024 |
| 18705288 | NOROVIRUS VACCINE AND METHODS OF USE | CHONG, KIMBERLY | — | §102§103§112 | Non-Final OA | — | Pending | Apr 26, 2024 |
| 18640092 | COMPOSITIONS AND METHODS OF PHOSPHOLIPASE A2 RECEPTOR CHIMERIC AUTOANTIBODY RECEPTOR T CELLS | OUSPENSKI, ILIA I | — | §101§102§112DP | Non-Final OA | — | Pending | Apr 19, 2024 |
| 18702258 | COMPOSITIONS USEFUL IN TREATMENT OF CDKL5 DEFICIENCY DISORDER (CDD) | SINGH, ANOOP KUMAR | — | §112DP | Non-Final OA | — | Pending | Apr 17, 2024 |
| 18635885 | USE OF ICOS-BASED CARS TO ENHANCE ANTITUMOR ACTIVITY AND CAR PERSISTENCE | BERTOGLIO, VALARIE E | 1632 | Other | Final Rejection | — | Pending | Apr 15, 2024 |
| 18625699 | METHODS FOR USING ENRICHED EXOSOMES AS A PLATFORM FOR MONITORING ORGAN STATUS | JUEDES, AMY E | 1644 | §102§112Other | Final Rejection | 29d overdue | Pending | Apr 03, 2024 |
| 18624860 | TARGETING CYTOTOXIC CELLS WITH CHIMERIC RECEPTORS FOR ADOPTIVE IMMUNOTHERAPY | AMICK, THOMAS RUSSE | — | DP | Non-Final OA | — | Pending | Apr 02, 2024 |
| 18695487 | COMPOSITIONS AND METHODS FOR T CELL TARGETED DELIVERY OF THERAPEUTIC AGENTS | AZPURU, CARLOS A | 1611 | §102§112Other | Non-Final OA | — | Pending | Mar 26, 2024 |
| 18611505 | Substituted Bimane Compounds and Methods of Use Thereof | GONZALEZ, LUISALBERTO | 1624 | §103 | Non-Final OA | — | Pending | Mar 20, 2024 |
| 18689656 | Universal Influenza Vaccine and Methods of Use | ZOU, NIANXIANG | — | §102§103§112 | Non-Final OA | — | Pending | Mar 06, 2024 |
| 18687571 | METHODS FOR EVALUATING TREATMENTS FOR BESTROPHINOPATHIES | BARRON, SEAN C | 1653 | §101§103 | Non-Final OA | — | Pending | Feb 28, 2024 |
| 18441543 | Fibrosis Model On A Chip | GANESAN, SUBA | 3774 | §102§103Other | Non-Final OA | — | Pending | Feb 14, 2024 |
| 18293711 | DESIGNER MEMBRANELESS ORGANELLES SEQUESTER NATIVE FACTORS FOR CONTROL OF CELL BEHAVIOR | CORDAS, EMILY ANN | 1632 | §103§112 | Non-Final OA | — | Pending | Jan 30, 2024 |
| 18292522 | STABILIZED PYROPHORIC MATERIALS FOR ONBOARD HYDROGEN GENERATION BY HYDROLYSIS AND RELATED METHODS | FELTON, AILEEN BAKER | 1734 | §102§112 | Non-Final OA | — | Pending | Jan 26, 2024 |
| 18292247 | COMPOSITIONS AND METHODS FOR ENHANCING CAR T CELL EFFICACY THROUGH THE ENGINEERED SECRETION OF C. PERFRINGENS NEURAMINIDASE | METCALF, MATTHEW CURRAN | — | §102§103§112 | Non-Final OA | — | Pending | Jan 25, 2024 |
| 18420525 | TARGETING CYTOTOXIC CELLS WITH CHIMERIC RECEPTORS FOR ADOPTIVE IMMUNOTHERAPY | REDDIG, PETER J | 1646 | §102§103§112Other | Non-Final OA | — | Pending | Jan 23, 2024 |
| 18420721 | CELLULAR COMPOSITIONS FOR TREATING BACK PAIN | RAHMAN, MASUDUR | 1633 | §102§103 | Non-Final OA | — | Pending | Jan 23, 2024 |
| 18416271 | TREATMENT OF SKIN LESIONS | SCHMITT, MICHAEL J | 1629 | §103Other | Non-Final OA | — | Pending | Jan 18, 2024 |
| 18413810 | ELECTRODE AND METHOD FOR PRODUCING THE SAME | SARCENO ROBLES, CHRISTIAN MANUEL | 3794 | §102§103 | Non-Final OA | — | Pending | Jan 16, 2024 |
| 18578997 | MODIFIED ADAPTERS FOR ENZYMATIC DNA DEAMINATION AND METHODS OF USE THEREOF FOR EPIGENETIC SEQUENCING OF FREE AND IMMOBILIZED DNA | CASH, KAILEY ELIZABETH | 1682 | §103§112DP | Non-Final OA | — | Pending | Jan 12, 2024 |
| 18411654 | SYSTEMS AND METHODS FOR PRODUCING MICRO-ENGINEERED MODELS OF THE HUMAN CERVIX | KNIGHT, TERESA E | 1634 | §103DP | Non-Final OA | — | Pending | Jan 12, 2024 |
| 18404733 | Nanocrystal Superparticles Through A Source-Sink Emulsion System | GROOMS, NOA WILLIAM FRAN | 2871 | §103§112 | Non-Final OA | — | Pending | Jan 04, 2024 |
| 18542382 | METHOD FOR TESTING AND SCREENING P38 MAP KINASE MODIFIERS | EMCH, GREGORY S | 1678 | §112Other | Non-Final OA | 31d overdue | Pending | Dec 15, 2023 |
| 18570153 | MATERIAL DEPOSITION ONTO AND RECOVERY FROM SURFACES VIA CONTACTLESS, REVERSIBLE DROPLET WETTING/DE-WETTING BY DIELECTRIC CHARGE INJECTION | SUN, CAITLYN MINGYUN | 1795 | §102 | Non-Final OA | 2d overdue | Pending | Dec 14, 2023 |
| 18569403 | ULTRA-HIGH THROUGHPUT ON-CHIP SYNTHESIS OF MICROGELS WITH TUNABLE MECHANICAL PROPERTIES | NILAND, PATRICK DENNIS | — | §103 | Non-Final OA | — | Pending | Dec 12, 2023 |
| 18567629 | RECOMBINANT ADENO-ASSOCIATED VIRUSES FOR LESCH-NYHAN DISORDERS AND USES THEREOF | GOMEZ RODRIGUEZ, JULIO WASHINGTON | — | §103§112 | Non-Final OA | — | Pending | Dec 06, 2023 |
| 18519972 | METHODS AND COMPOSITIONS FOR TREATING METASTATIC BREAST CANCER AND OTHER CANCERS IN THE BRAIN | ARON, KIMBERLY A | 1633 | DP | Non-Final OA | — | Pending | Nov 27, 2023 |
| 18563707 | MONITORING OF UPPER LIMB MOVEMENTS TO DETECT STROKE | TOTH, KAREN E | 3791 | §101§102§103§112 | Final Rejection | 38d overdue | Pending | Nov 22, 2023 |
| 18560153 | COMPOSITIONS AND METHODS FOR DEBULKING VIRUS OR MICROORGANISM LOAD IN THE ORAL CAVITY | MOAZZAMI, NAGHMEH NINA | 1652 | §103§112Other | Final Rejection | 4d overdue | Pending | Nov 10, 2023 |
| 18502338 | METHODS AND APPARATUS FOR DEEP LEARNING BASED IMAGE RECONSTRUCTION | RIVERA-MARTINEZ, GUILLERMO M | 2677 | §102§103 | Non-Final OA | — | Pending | Nov 06, 2023 |
| 18501859 | Methods and Compositions for Treating, Ameliorating, and/or Preventing Chronic Kidney Disease (CKD) and Complications thereof by Regulating DPEP1, CASP9, ACSS2 and/or FASN | VYAS, KEYUR ANILKUMAR | 1637 | §102§112 | Non-Final OA | — | Pending | Nov 03, 2023 |
| 18558013 | Lipid Nanoparticle Therapeutics that Evade the Immune Response | HOWARD, ZACHARY C | 1674 | §102§112 | Non-Final OA | — | Pending | Oct 30, 2023 |
| 18557834 | COMPOSITIONS AND METHODS OF TREATING SEPSIS IN PATIENTS USING ANTI-LIGHT ANTIBODIES | SCHWECHTER, BRANDON ROSS | 1798 | §102§112 | Non-Final OA | — | Pending | Oct 27, 2023 |
| 18556944 | COMPOSITIONS AND METHODS FOR IN VIVO NUCLEASE-MEDIATED GENE TARGETING FOR THE TREATMENT OF GENETIC DISORDERS | SULLIVAN, STEPHANIE LAUREN | 1635 | §103§112DP | Non-Final OA | — | Pending | Oct 24, 2023 |
| 18556328 | MACHINE LEARNING BASED HISTOPATHOLOGICAL RECURRENCE PREDICTION MODELS FOR HPV+ HEAD / NECK SQUAMOUS CELL CARCINOMA | MINCHELLA, KAITLYN L | — | §103§112 | Non-Final OA | — | Pending | Oct 19, 2023 |
| 18555214 | METHODS TO DETERMINE TREATMENT EFFICACY WITH GAMMA-DELTA T CELLS | LANDSMAN, ROBERT S | 1647 | §103 | Non-Final OA | — | Pending | Oct 12, 2023 |
| 18483862 | Nanoparticle Ink Based Patterning Of Inorganic Materials | YOUNG, WILLIAM D | 1761 | §102§112 | Non-Final OA | — | Pending | Oct 10, 2023 |
| 18554748 | COMPOSITIONS USEFUL FOR TREATING SPINAL AND BULBAR MUSCULAR ATROPHY (SBMA) | SHIBUYA, MARK LANCE | 1631 | §103§112Other | Non-Final OA | — | Pending | Oct 10, 2023 |
| 18482096 | STIFFNESS TUNABLE BIOMIMETIC DECELLULARIZED EXTRACELLULAR MATRIX-BASED MATERIAL SYSTEMS | SCHUBERG, LAURA J | 3774 | §102§103 | Non-Final OA | — | Pending | Oct 06, 2023 |
| 18477584 | Enhancing Activity of CAR T Cells by Co-Introducing a Bispecific Antibody | SANG, HONG | 1646 | §112DP | Non-Final OA | — | Pending | Sep 29, 2023 |
| 18552086 | CAR-T DELIVERY OF SYNTHETIC PEPTIDE THERAPEUTICS | PETERS, ALEC JON | 1641 | §102§103§112Other | Non-Final OA | — | Pending | Sep 22, 2023 |
| 18549252 | COMPOSITIONS AND METHODS FOR ASSESSING AND TREATING T CELL DYSFUNCTION | PERSONS, JENNA L | 1637 | §101§102§103§112 | Non-Final OA | — | Pending | Sep 06, 2023 |
| 18264885 | COMPOSITIONS AND METHODS FOR TREATING PULMONARY ARTERIAL HYPERTENSION (PAH) AND OTHER DISORDERS | LIPPOLIS, ALEXANDRA ROSE | 1637 | §102§103§112 | Non-Final OA | — | Pending | Aug 09, 2023 |
| 18365318 | Magnetic Separation Filters And Microfluidic Devices Using Magnetic Separation Filters | GERIDO, DWAN A | 1797 | §102 | Final Rejection | 17d overdue | Pending | Aug 04, 2023 |
| 18263085 | COMPOSITIONS AND METHODS FOR TREATMENT OF NIEMANN PICK TYPE A DISEASE | TATGE, LEXUS MARC | 1637 | §102§103§112 | Non-Final OA | — | Pending | Jul 26, 2023 |
| 18260786 | COMPOSITIONS FOR TREATING FRIEDREICH'S ATAXIA | MIANO, JOSEPH PAUL | 1631 | §103DP | Final Rejection | 27d | Pending | Jul 09, 2023 |
| 18259439 | MICROFLUIDIC PLATFORMS FOR LARGE SCALE NANOPARTICLE FORMULATIONS | MUI, CHRISTINE T | 1797 | §103 | Non-Final OA | — | Pending | Jun 27, 2023 |
| 18339565 | CD20 THERAPIES, CD22 THERAPIES, AND COMBINATION THERAPIES WITH A CD19 CHIMERIC ANTIGEN RECEPTOR (CAR)-EXPRESSING CELL | REDDIG, PETER J | 1646 | §103Other | Final Rejection | 55d | Pending | Jun 22, 2023 |
| 18331331 | HIDDEN ANTIBIOTICS IN THE HUMAN PROTEOME | VARADARAJ, ARCHANA | 1658 | §102§103 | Non-Final OA | — | Pending | Jun 08, 2023 |
| 18327981 | Multimodal Proximity and Visuotactile Sensing Through Transmissive Membrane | GRAY, SUNGHEE Y | 2800 | §103§112Other | Final Rejection | — | Pending | Jun 02, 2023 |
| 18255398 | ENGINEERING OF ORGANOID CULTURE FOR ENHANCED ORGANOGENESIS IN A DISH | FISHER, BRITTANY I | 1796 | §102 | Non-Final OA | 60d overdue | Pending | Jun 01, 2023 |
| 18250764 | A HUMAN VASCULAR INJURY-ON-A-CHIP MODEL OF HEMOSTASIS | ALABI, OYELEYE A | 1797 | §101§102 | Non-Final OA | 56d | Pending | Apr 27, 2023 |
| 18250471 | VIRAL VECTORS ENCODING CANINE INSULIN FOR TREATMENT OF METABOLIC DISEASES IN DOGS | LI, BAO Q | 1654 | §102§103§112 | Non-Final OA | — | Pending | Apr 25, 2023 |
| 18246872 | COMPOSITIONS AND METHODS FOR TREATMENT OF FABRY DISEASE | VIJAYARAGHAVAN, JAGAMYA NMN | 1633 | §103§112DP | Final Rejection | 73d overdue | Pending | Mar 28, 2023 |
| 18246604 | METHODS AND COMPOSITIONS FOR IN SITU IMMUNE PROFILING OF HEART TRANSPLANT BIOPSIES | CARTER, SANDRA DILLAHUNT | 1674 | §101§112 | Non-Final OA | — | Pending | Mar 24, 2023 |
| 18187131 | Nanocomposite Films And Methods For Producing The Same | REDDY, KARUNA P | 1764 | §102§103§112 | Final Rejection | 28d | Pending | Mar 21, 2023 |
| 18042726 | VIRAL VECTORS ENCODING GLP-1 RECEPTOR AGONIST FUSIONS AND USES THEREOF IN TREATING METABOLIC DISEASES | HUMPHRIES, NICHOLAS ADAM | 1631 | §103DP | Final Rejection | — | Pending | Feb 23, 2023 |
| 18040971 | RECOMBINANT ADENO-ASSOCIATED VIRUS FOR TREATMENT OF GRN-ASSOCIATED ADULT-ONSET NEURODEGENERATION | THUESON, HANNA MARIE | 1638 | §103 | Final Rejection | 74d overdue | Pending | Feb 07, 2023 |
| 18040648 | NOVEL AAV CAPSIDS AND COMPOSITIONS CONTAINING SAME | SPENCER, ANDREA LYNNE MORRIS | 1631 | §102§103§112DPOther | Non-Final OA | — | Pending | Feb 05, 2023 |
| 18162236 | METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS | GROOMS, TIFFANY NICOLE | 1637 | §103§112DP | Final Rejection | — | Pending | Jan 31, 2023 |
| 18156442 | COMPOSITIONS AND METHODS OF CHIMERIC AUTOANTIBODY RECEPTOR T CELLS | LOCKARD, JON MCCLELLAND | 1647 | §112Other | Non-Final OA | — | Pending | Jan 19, 2023 |
| 18061633 | GENE THERAPY FOR OCULAR DISORDERS | VIVLEMORE, TRACY ANN | 1638 | §103§112 | Non-Final OA | — | Pending | Dec 05, 2022 |
| 17928170 | Compositions and Methods for Detecting Respiratory Viruses Including Coronaviruses | BAUSCH, SARAE L | 1699 | §101§102§112 | Non-Final OA | 3d overdue | Pending | Nov 28, 2022 |
| 18056562 | Polymer Blends Having Improved Ion Conductivity, Devices, and Methods | CULLEN, SEAN P | 1725 | §103§112 | Final Rejection | 26d | Pending | Nov 17, 2022 |
| 17998330 | COMPOSITIONS USEFUL IN TREATMENT OF KRABBE DISEASE | RIGA, MICHAEL ANGELO | 1634 | §103§112 | Non-Final OA | 34d | Pending | Nov 09, 2022 |
| 17997110 | COMPOSITIONS AND METHODS FOR REDUCING NUCLEASE EXPRESSION AND OFF-TARGET ACTIVITY USING A PROMOTER WITH LOW TRANSCRIPTIONAL ACTIVITY | SPENCER, ANDREA LYNNE MORRIS | 1631 | §103§112Other | Non-Final OA | 6d | Pending | Oct 25, 2022 |
| 17997004 | COMPOSITIONS AND USES THEREOF FOR TREATMENT OF ANGELMAN SYNDROME | BRETZ, COREY LANE | 1635 | §103§112 | Final Rejection | — | Pending | Oct 24, 2022 |
| 17936654 | METHOD OF TREATING OR AMELIORATING CANCERS DRIVEN BY RECEPTOR TYROSINE KINASE FUSION ONCOGENES, AND COMPOSITIONS FOR THE SAME | ROBINSON, MIKHAIL O'DONNEL | 1627 | §103 | Non-Final OA | 10d overdue | Pending | Sep 29, 2022 |
| 17951985 | ANALYSIS OF PLEURAL LINES FOR THE DIAGNOSIS OF LUNG CONDITIONS | OSINSKI, MICHAEL S | 2674 | §103 | Final Rejection | 4d overdue | Pending | Sep 23, 2022 |
| 17905129 | METHODS OF USING A MULTI-ANALYTE APPROACH FOR DIAGNOSIS AND STAGING A DISEASE | HANEY, AMANDA MARIE | 1682 | §101§112 | Non-Final OA | 77d overdue | Pending | Aug 26, 2022 |
| 17904899 | TREATING AUTOSOMAL DOMINANT BESTROPHINOPATHIES AND METHODS FOR EVALUATING SAME | VIVLEMORE, TRACY ANN | 1638 | §102§112DP | Final Rejection | — | Pending | Aug 24, 2022 |
| 17801959 | TISSUE CULTURE MEDIA FOR SURVIVAL AND ENGRAFTMENT OF HUMAN PANCREATIC ISLETS | TICHY, JENNIFER M.H. | 1653 | §103 | Final Rejection | 52d overdue | Pending | Aug 24, 2022 |
| 17904903 | TREATING AUTOSOMAL RECESSIVE BESTROPHINOPATHIES AND METHODS FOR EVALUATING SAME | VIVLEMORE, TRACY ANN | 1638 | §102§112Other | Final Rejection | — | Pending | Aug 24, 2022 |
| 17818854 | METHODS OF INCREASING RESPONSE TO CANCER RADIATION THERAPY | GUSTILO, ESTELLA M | 1646 | §103Other | Non-Final OA | 93d overdue | Pending | Aug 10, 2022 |
| 17871702 | PROGRAMMABLE ENZYME-ASSISTED SELECTIVE EXPONENTIAL AMPLIFICATION FOR SENSITIVE DETECTION OF RARE MUTANT ALLELES | LU, FRANK WEI MIN | 1683 | §112 | Non-Final OA | 22d | Pending | Jul 22, 2022 |
| 17867335 | COMPOSITIONS AND METHODS FOR GENERATION OF RETINAL GANGLION CELLS FROM INDUCIBLE PLURIPOTENT STEM CELLS FOR THE TREATMENT OF PROGRESSIVE OPTIC NEUROPATHIES, INCLUDING GLAUCOMA | STAVROU, CONSTANTINA E | 1632 | §102§103 | Non-Final OA | — | Pending | Jul 18, 2022 |
| 17842530 | ADENO-ASSOCIATED VIRUS VIRIONS WITH VARIANT CAPSID AND METHODS OF USE THEREOF | MONTANARI, DAVID A | 1632 | §112 | Final Rejection | — | Pending | Jun 16, 2022 |
| 17786147 | COMPOSITIONS AND METHODS FOR HEMOGLOBIN PRODUCTION | PERSONS, JENNA L | 1637 | §103§112 | Non-Final OA | 16d overdue | Pending | Jun 16, 2022 |
| 17738480 | Composite Energetic Material With Self-Regulated Temperature | KRCHA, MATTHEW D | 1796 | §103 | Final Rejection | — | Pending | May 06, 2022 |
| 17718922 | ENZYMATIC TARGETING CARIOGENIC BACTERIAL-FUNGAL BIOFILM INTERACTION | ROBERTS, LEZAH | 1612 | §103 | Final Rejection | 41d | Pending | Apr 12, 2022 |
| 17656660 | TERRITORY MAPPING IN PSEUDO-CONTINUOUS ARTERIAL SPIN LABELING | MERRIAM, AARON ROGERS | 3791 | §101§103§112 | Non-Final OA | 15d | Pending | Mar 28, 2022 |
| 17636950 | UROFLOW MONITORING SYSTEM AND METHOD | MUSTANSIR, ABID A | 3791 | §103 | Final Rejection | 34d | Pending | Feb 21, 2022 |
| 17672438 | COMPOSITIONS AND METHODS FOR INHIBITING BIOFILM DEPOSITION AND PRODUCTION | DABKOWSKI, ERINNE R | 1654 | DP | Non-Final OA | — | Pending | Feb 15, 2022 |
| 17627260 | DEVICES AND METHODS FOR RAPID SCREENING OF DRUGS OF ABUSE AND OTHER ANALYTES | SVEIVEN, MICHAEL CAMERON | 1678 | §102§103 | Final Rejection | 51d overdue | Pending | Jan 14, 2022 |
| 17563392 | COMPOSITIONS, COMPRISING IMPROVED IL-12 GENETIC CONSTRUCTS AND VACCINES, IMMUNOTHERAPEUTICS AND METHODS OF USING THE SAME | CARTER, SANDRA DILLAHUNT | 1674 | §112DP | Final Rejection | — | Pending | Dec 28, 2021 |
| 17523492 | Methods and Compositions for Treatment of Disorders and Diseases Involving RDH12 | YU, DAVID TUYANG | 1635 | §102§103§112 | Final Rejection | — | Pending | Nov 10, 2021 |
| 17607837 | MICRO-RNA SITE BLOCKING OLIGONUCLEOTIDES FOR THE TREATMENT OF EPILEPTIC ENCEPHALOPATHY AND NEURODEVELOPMENTAL DISORDERS | SULLIVAN, STEPHANIE LAUREN | 1635 | §103 | Final Rejection | 6d | Pending | Oct 29, 2021 |
| 17602730 | METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS | BATES, KEENAN ALEXANDER | 1631 | §102§103§112 | Non-Final OA | — | Pending | Oct 08, 2021 |
| 17602277 | METHODS AND COMPOSITIONS FOR PROGRAMMING T CELL DIFFERENTIATION AND ENHANCING T CELL PROLIFERATION | WESTON, ALYSSA G | 1633 | §102§103 | Final Rejection | — | Pending | Oct 07, 2021 |
| 17601581 | COMPOSITIONS AND METHODS FOR IN UTERO GENE EDITING FOR MONOGENIC LUNG DISEASE | BATES, KEENAN ALEXANDER | 1631 | §103§112 | Final Rejection | 5d | Pending | Oct 05, 2021 |
| 17424363 | MICROCATHETER FOR THERAPEUTIC AND/OR DIAGNOSTIC INTERVENTIONS IN THE SUBARACHNOID SPACE | LUU, TIMOTHY TUAN | 3795 | §103§112 | Non-Final OA | — | Pending | Jul 20, 2021 |
| 17356146 | IN VIVO DETECTION OF EGFR MUTATION IN GLIOBLASTOMA VIA MRI SIGNATURE CONSISTENT WITH DEEP PERITUMORAL INFILTRATION | SCHULTZHAUS, JANNA NICOLE | 1685 | §101§103§112 | Non-Final OA | 36d overdue | Pending | Jun 23, 2021 |
| 17298599 | AMPA RECEPTOR ANTAGONISTS SPECIFIC FOR CALCIUM PERMEABLE AMPA RECEPTORS AND METHODS OF TREATMENT THEREWITH | COLEMAN, BRENDA LIBBY | 1624 | §112 | Non-Final OA | — | Pending | May 31, 2021 |
| 17294401 | COMPOSITIONS AND METHODS FOR THE CYTOPLASMIC DELIVERY OF ANTIBODIES AND OTHER PROTEINS | AEDER, SEAN E | 1642 | §103§112 | Final Rejection | — | Pending | May 15, 2021 |
| 17199926 | Rapid And Ultrasensitive Analyte Detection For Screening In Community Settings | RAMADAN, OMAR | 1678 | §103 | Final Rejection | — | Pending | Mar 12, 2021 |
| 17097997 | COMPOSITIONS FOR DRG-SPECIFIC REDUCTION OF TRANSGENE EXPRESSION | VIVLEMORE, TRACY ANN | 1638 | §102§112DP | Non-Final OA | — | Pending | Nov 13, 2020 |
| 16975541 | NOVEL ADENO-ASSOCIATED VIRUS (AAV) VECTORS, AAV VECTORS HAVING REDUCED CAPSID DEAMIDATION AND USES THEREFOR | WANG, RUIXUE | 1672 | §103 | Final Rejection | — | Pending | Aug 25, 2020 |
| 16971995 | METHODS AND COMPOSITIONS COMPRISING CART AND A SMAC MIMETIC | CONNORS, ALEXANDRA F | 1634 | §103§112 | Final Rejection | — | Pending | Aug 21, 2020 |
| 16435257 | TREATMENT OF CANCER USING ANTI-CD19 CHIMERIC ANTIGEN RECEPTOR | BRISTOL, LYNN ANNE | 1643 | §103§112Other | Non-Final OA | 132d overdue | Pending | Jun 07, 2019 |
| 16317943 | TREATMENT AND PREVENTION OF CYTOKINE RELEASE SYNDROME USING A CHIMERIC ANTIGEN RECEPTOR IN COMBINATION WITH A KINASE INHIBITOR | LU, CHENG | 1642 | §103§112 | Non-Final OA | 38d overdue | Pending | Jan 15, 2019 |
| 16093758 | COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN EXPRESSION | MARTINEZ, TARA L | 1654 | DP | Final Rejection | 16d overdue | Pending | Oct 15, 2018 |
| 16081346 | THERAPY FOR FRONTOTEMPORAL DEMENTIA | CONNORS, ALEXANDRA F | 1634 | §103 | Final Rejection | — | Pending | Aug 30, 2018 |
| 15553805 | ROBUST SMART FILM: REVERSIBLY SWITCHING FROM HIGH TRANSPARENCY TO ANGLE-INDEPENDENT STRUCTURAL COLOR DISPLAY | MILLER, BETHANY MACKENZIE | 1787 | §103§112 | Non-Final OA | — | Pending | Aug 25, 2017 |
| 15327794 | SUBSET-OPTIMIZED CHIMERIC ANTIGEN RECEPTOR-CONTAINING T-CELLS | POPA, ILEANA | 1633 | §103 | Final Rejection | 5d overdue | Pending | Jan 20, 2017 |
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