Prosecution Insights
Prosecution Insights
Technology area: Biotechnology & Pharmaceuticals
126 pending office actions • 58 art units • 114 examiners • 0 of 126 (0%) have an AI response strategy ready • 99 patents granted in the last 365 days
The Trustees of the University of Pennsylvania manage a portfolio of 126 pending office actions within the Biotechnology & Pharmaceuticals technology area. These actions are distributed among 115 distinct examiners and 56 distinct art units. TRACY ANN VIVLEMORE is the busiest examiner for the university, currently handling 4 pending actions. The 56 distinct art units reflect the diverse nature of the university's research and patenting activities in the biotech and pharmaceutical sectors.
With 115 distinct examiners involved, the university's prosecution strategy involves navigating an array of individual examiner preferences and specialized unit practices. Despite the total of 126 pending office actions, the busiest examiner only manages 4, indicating that the workload is dispersed across the USPTO. This distribution suggests that the university's patent applications are not concentrated in a single niche but span many different scientific disciplines. With 126 pending office actions, the university is an active participant in the patent acquisition process. The involvement of a large group of examiners ensures that the university's innovations are being reviewed by a wide range of technical experts.
Based on the USPTO statutory response window for each pending office action. 35 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 35 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 + other | 14 (11%) |
| §103 only | 20 (16%) |
| §102 only | 3 (2%) |
| §112 only | 7 (6%) |
| Double-patenting only | 4 (3%) |
| Double-patenting + other | 21 (17%) |
| Multi-statute (no §101) | 56 (44%) |
| No statute on record | 1 (1%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| VIVLEMORE, TRACY ANN | 4 | 73.0% | +6.4% |
| LEONARD, ARTHUR S | 2 | 50.6% | +50.5% |
| BARRON, SEAN C | 2 | 52.8% | +30.7% |
| JUEDES, AMY E | 2 | 44.8% | +41.8% |
| REDDIG, PETER J | 2 | 57.9% | +40.2% |
| PERSONS, JENNA L | 2 | 50.8% | +61.7% |
| CARTER, SANDRA DILLAHUNT | 2 | 56.2% | +29.0% |
| SPENCER, ANDREA LYNNE MORRIS | 2 | 22.2% | +35.7% |
| TICHY, JENNIFER M.H. | 2 | 64.9% | +34.5% |
| BATES, KEENAN ALEXANDER | 2 | 44.9% | +79.8% |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 16435257 | TREATMENT OF CANCER USING ANTI-CD19 CHIMERIC ANTIGEN RECEPTOR | BRISTOL, LYNN ANNE | 132d overdue |
| 17905129 | METHODS OF USING A MULTI-ANALYTE APPROACH FOR DIAGNOSIS AND STAGING A DISEASE | HANEY, AMANDA MARIE | 77d overdue |
| 17627260 | DEVICES AND METHODS FOR RAPID SCREENING OF DRUGS OF ABUSE AND OTHER ANALYTES | SVEIVEN, MICHAEL CAMERON | 51d overdue |
| 18563707 | MONITORING OF UPPER LIMB MOVEMENTS TO DETECT STROKE | TOTH, KAREN E | 38d overdue |
| 16317943 | TREATMENT AND PREVENTION OF CYTOKINE RELEASE SYNDROME USING A CHIMERIC ANTIGEN RECEPTOR IN COMBINATION WITH A KINASE INHIBITOR | LU, CHENG | 38d overdue |
| 17356146 | IN VIVO DETECTION OF EGFR MUTATION IN GLIOBLASTOMA VIA MRI SIGNATURE CONSISTENT WITH DEEP PERITUMORAL INFILTRATION | SCHULTZHAUS, JANNA NICOLE | 36d overdue |
| 18625699 | METHODS FOR USING ENRICHED EXOSOMES AS A PLATFORM FOR MONITORING ORGAN STATUS | JUEDES, AMY E | 29d overdue |
| 17786147 | COMPOSITIONS AND METHODS FOR HEMOGLOBIN PRODUCTION | PERSONS, JENNA L | 16d overdue |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17801959 | TISSUE CULTURE MEDIA FOR SURVIVAL AND ENGRAFTMENT OF HUMAN PANCREATIC ISLETS | TICHY, JENNIFER M.H. | 52d overdue |
| 18625699 | METHODS FOR USING ENRICHED EXOSOMES AS A PLATFORM FOR MONITORING ORGAN STATUS | JUEDES, AMY E | 29d overdue |
| 17786147 | COMPOSITIONS AND METHODS FOR HEMOGLOBIN PRODUCTION | PERSONS, JENNA L | 16d overdue |
| 17601581 | COMPOSITIONS AND METHODS FOR IN UTERO GENE EDITING FOR MONOGENIC LUNG DISEASE | BATES, KEENAN ALEXANDER | 5d |
| 17997110 | COMPOSITIONS AND METHODS FOR REDUCING NUCLEASE EXPRESSION AND OFF-TARGET ACTIVITY USING A PROMOTER WITH LOW TRANSCRIPTIONAL ACTIVITY | SPENCER, ANDREA LYNNE MORRIS | 6d |
| 16753634 | Tissue Engineered "Axon Fusion" for Immediate Recovery Following Axon Transection | TICHY, JENNIFER M.H. | 14d |
| 18339565 | CD20 THERAPIES, CD22 THERAPIES, AND COMBINATION THERAPIES WITH A CD19 CHIMERIC ANTIGEN RECEPTOR (CAR)-EXPRESSING CELL | REDDIG, PETER J | 55d |
| 18994948 | RECOMBINANT AAV HAVING AAV CLADE D AND CLADE E CAPSIDS AND COMPOSITIONS CONTAINING SAME | LEONARD, ARTHUR S | — |
| Art Unit | Apps |
|---|---|
| 1631 | 7 |
| 1637 | 6 |
| 1638 | 5 |
| 1632 | 4 |
| 1646 | 4 |
| 1633 | 4 |
| 1674 | 4 |
| 1644 | 3 |
| 1653 | 3 |
| 1635 | 3 |
| App # | Title | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|
| 19059620 | METHODS AND APPARATUS FOR DEEP LEARNING BASED ATTENUATION CORRECTION FOR IMAGE RECONSTRUCTION | HOANG, HAN DINH | 2661 | §103 | Non-Final OA | — | Pending | Feb 21, 2025 |
| 18994948 | RECOMBINANT AAV HAVING AAV CLADE D AND CLADE E CAPSIDS AND COMPOSITIONS CONTAINING SAME | LEONARD, ARTHUR S | — | §101§103§112 | Non-Final OA | — | Pending | Jan 15, 2025 |
| 18949254 | INTRAVASCULAR CERVICAL SYMPATHETIC NERVE STIMULATION SYSTEM | JIAN, SHIRLEY XUEYING | — | §102§103 | Non-Final OA | — | Pending | Nov 15, 2024 |
| 18856855 | BIODEGRADABLE LIPIDOIDS AND COMPOSITIONS AND METHODS OF USE THEREOF FOR TARGETED DELIVERY | DAVIS, BRIAN J | — | §102§112 | Non-Final OA | — | Pending | Oct 14, 2024 |
| 18904575 | Compositions and Methods for Targeting Lipid Nanoparticle Therapeutics to Stem Cells | WESTERBERG, NISSA M | 1618 | §103DP | Final Rejection | 18d overdue | Pending | Oct 02, 2024 |
| 18853162 | BIODEGRADABLE LIPIDOIDS AND COMPOSITIONS AND METHODS OF USE THEREOF FOR LIVER TARGETED DELIVERY | TCHERKASSKAYA, OLGA V | — | §103§112DP | Non-Final OA | — | Pending | Oct 01, 2024 |
| 18849467 | DEEP LEARNING SUPER RESOLUTION OF MEDICAL IMAGES | RHIM, WOO CHUL | 2676 | §103 | Non-Final OA | — | Pending | Sep 20, 2024 |
| 18846153 | METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR ASSESSING VISUAL FUNCTION USING VIRTUAL MOBILITY TESTS | SRIDHAR, SAMANVITHA | — | §102§103§112 | Non-Final OA | — | Pending | Sep 11, 2024 |
| 18822614 | PUPILLOMETER | LIU, CHU CHUAN | — | §101§103§112 | Non-Final OA | — | Pending | Sep 03, 2024 |
| 18799659 | MODULATORS OF MYOCYTE LIPID ACCUMULATION AND INSULIN RESISTANCE AND METHODS OF USE THEREOF | VAJDA, KRISTIN ANN | 1622 | §102§112DP | Non-Final OA | — | Pending | Aug 09, 2024 |
| 18832191 | VERSATILE ADHESION-BASED GRIPPING VIA AN UNSTRUCTURED VARIABLE STIFFNESS MEMBRANE | QURESHI, REHMAN AHMED | — | §102§103 | Non-Final OA | — | Pending | Jul 23, 2024 |
| 18773968 | COMPOSITIONS AND METHODS FOR TREATMENT OF ACUTE LUNG INJURY | LIEB, JEANETTE M | — | §103DP | Non-Final OA | — | Pending | Jul 16, 2024 |
| 18771929 | NATURAL AND ARTIFICIAL INTELLIGENCE FOR ROBUST AUTOMATIC ANATOMY SEGMENTATION | LEMIEUX, IAN L | 2669 | §101§102 | Non-Final OA | — | Pending | Jul 12, 2024 |
| 18727953 | COMPOSITIONS USEFUL IN TREATMENT OF METACHROMATIC LEUKODYSTROPHY | WILSON, MICHAEL C | — | §102§112Other | Non-Final OA | — | Pending | Jul 10, 2024 |
| 18750780 | ANTI-CAR COMPOSITIONS AND METHODS | BOESEN, AGNIESZKA | — | §102§103 | Non-Final OA | — | Pending | Jun 21, 2024 |
| 18721210 | METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR CAUSAL TRAINING OF PHYSICS-INFORMED NEURAL NETWORKS | GORMLEY, AARON PATRICK | — | §102§103 | Non-Final OA | — | Pending | Jun 18, 2024 |
| 18720823 | COMPUTER-IMPLEMENTED METHODS AND ASSOCIATED SYSTEMS FOR DETECTING MALIGNANCY | JACOB, OOMMEN | 3797 | §112 | Non-Final OA | 33d | Pending | Jun 17, 2024 |
| 18717294 | COMPOSITIONS AND METHODS FOR PREVENTION OR REDUCTION OF CARPA | VOLKOV, ALEXANDER ALEXANDROVIC | 1612 | §102§103§112 | Non-Final OA | — | Pending | Jun 06, 2024 |
| 18716088 | ANISAMIDE-CONTAINING LIPIDS AND COMPOSITIONS AND METHODS OF USE THEREOF | SONG, JIANFENG | 1613 | §112 | Final Rejection | — | Pending | Jun 03, 2024 |
| 18675268 | Scalable, Printable, Patterned Sheet Of High Mobility Graphene On Flexible Substrates | MIGGINS, MICHAEL C | 1782 | §102§103DPOther | Final Rejection | 70d | Pending | May 28, 2024 |
| 18712323 | COMPOSITIONS AND METHODS FOR TREATMENT OF FABRY DISEASE | BARRON, SEAN C | — | §103 | Non-Final OA | — | Pending | May 22, 2024 |
| 18670290 | COMPOSITIONS AND METHODS FOR TREATING B-LYMPHOID MALIGNANCIES | LEONARD, ARTHUR S | — | §102§103§112DP | Non-Final OA | — | Pending | May 21, 2024 |
| 18668785 | ROBOTIC MICROCAPSULE ASSEMBLIES WITH EMERGENT MOBILITY FOR TARGETED TREATMENT AND DRUG DELIVERY | YANG, YI-SHAN | 1616 | §103§112 | Non-Final OA | — | Pending | May 20, 2024 |
| 18661538 | COMPOSITIONS FOR AND METHODS OF TREATING AND/OR PREVENTING MALARIA | DUFFY, PATRICIA ANN | 1645 | §101§102§112 | Non-Final OA | — | Pending | May 10, 2024 |
| 18709415 | GENE THERAPY FOR TREATMENT OF MUCOPOLYSACCHARIDOSIS IIIA | ALLEN, SARAH ELIZABETH | — | §102§103§112Other | Non-Final OA | — | Pending | May 10, 2024 |
| 18709324 | FUSION PROTEIN | EDGINGTONGIORDANO, FRANCESCA | — | §102§103 | Non-Final OA | — | Pending | May 10, 2024 |
| 18654958 | HUMANIZED F77 ANTIBODIES AND FRAGMENTS THEREOF | TAYLOR, LIA ELAN | — | §102§103§112 | Non-Final OA | — | Pending | May 03, 2024 |
| 18705288 | NOROVIRUS VACCINE AND METHODS OF USE | CHONG, KIMBERLY | — | §102§103§112 | Non-Final OA | — | Pending | Apr 26, 2024 |
| 18640092 | COMPOSITIONS AND METHODS OF PHOSPHOLIPASE A2 RECEPTOR CHIMERIC AUTOANTIBODY RECEPTOR T CELLS | OUSPENSKI, ILIA I | — | §101§102§112DP | Non-Final OA | — | Pending | Apr 19, 2024 |
| 18702258 | COMPOSITIONS USEFUL IN TREATMENT OF CDKL5 DEFICIENCY DISORDER (CDD) | SINGH, ANOOP KUMAR | — | §112DP | Non-Final OA | — | Pending | Apr 17, 2024 |
| 18635885 | USE OF ICOS-BASED CARS TO ENHANCE ANTITUMOR ACTIVITY AND CAR PERSISTENCE | BERTOGLIO, VALARIE E | 1632 | Other | Final Rejection | — | Pending | Apr 15, 2024 |
| 18625699 | METHODS FOR USING ENRICHED EXOSOMES AS A PLATFORM FOR MONITORING ORGAN STATUS | JUEDES, AMY E | 1644 | §102§112Other | Final Rejection | 29d overdue | Pending | Apr 03, 2024 |
| 18624860 | TARGETING CYTOTOXIC CELLS WITH CHIMERIC RECEPTORS FOR ADOPTIVE IMMUNOTHERAPY | AMICK, THOMAS RUSSE | — | DP | Non-Final OA | — | Pending | Apr 02, 2024 |
| 18695487 | COMPOSITIONS AND METHODS FOR T CELL TARGETED DELIVERY OF THERAPEUTIC AGENTS | AZPURU, CARLOS A | 1611 | §102§112Other | Non-Final OA | — | Pending | Mar 26, 2024 |
| 18611505 | Substituted Bimane Compounds and Methods of Use Thereof | GONZALEZ, LUISALBERTO | 1624 | §103 | Non-Final OA | — | Pending | Mar 20, 2024 |
| 18687571 | METHODS FOR EVALUATING TREATMENTS FOR BESTROPHINOPATHIES | BARRON, SEAN C | 1653 | §101§103 | Non-Final OA | — | Pending | Feb 28, 2024 |
| 18441543 | Fibrosis Model On A Chip | GANESAN, SUBA | 3774 | §102§103Other | Non-Final OA | — | Pending | Feb 14, 2024 |
| 18293711 | DESIGNER MEMBRANELESS ORGANELLES SEQUESTER NATIVE FACTORS FOR CONTROL OF CELL BEHAVIOR | CORDAS, EMILY ANN | 1632 | §103§112 | Non-Final OA | — | Pending | Jan 30, 2024 |
| 18292522 | STABILIZED PYROPHORIC MATERIALS FOR ONBOARD HYDROGEN GENERATION BY HYDROLYSIS AND RELATED METHODS | FELTON, AILEEN BAKER | 1734 | §102§112 | Non-Final OA | — | Pending | Jan 26, 2024 |
| 18292247 | COMPOSITIONS AND METHODS FOR ENHANCING CAR T CELL EFFICACY THROUGH THE ENGINEERED SECRETION OF C. PERFRINGENS NEURAMINIDASE | METCALF, MATTHEW CURRAN | — | §102§103§112 | Non-Final OA | — | Pending | Jan 25, 2024 |
| 18420525 | TARGETING CYTOTOXIC CELLS WITH CHIMERIC RECEPTORS FOR ADOPTIVE IMMUNOTHERAPY | REDDIG, PETER J | 1646 | §102§103§112Other | Non-Final OA | — | Pending | Jan 23, 2024 |
| 18420721 | CELLULAR COMPOSITIONS FOR TREATING BACK PAIN | RAHMAN, MASUDUR | 1633 | §102§103 | Non-Final OA | — | Pending | Jan 23, 2024 |
| 18413810 | ELECTRODE AND METHOD FOR PRODUCING THE SAME | SARCENO ROBLES, CHRISTIAN MANUEL | 3794 | §102§103 | Non-Final OA | — | Pending | Jan 16, 2024 |
| 18578997 | MODIFIED ADAPTERS FOR ENZYMATIC DNA DEAMINATION AND METHODS OF USE THEREOF FOR EPIGENETIC SEQUENCING OF FREE AND IMMOBILIZED DNA | CASH, KAILEY ELIZABETH | 1682 | §103§112DP | Non-Final OA | — | Pending | Jan 12, 2024 |
| 18411654 | SYSTEMS AND METHODS FOR PRODUCING MICRO-ENGINEERED MODELS OF THE HUMAN CERVIX | KNIGHT, TERESA E | 1634 | §103DP | Non-Final OA | — | Pending | Jan 12, 2024 |
| 18404733 | Nanocrystal Superparticles Through A Source-Sink Emulsion System | GROOMS, NOA WILLIAM FRAN | 2871 | §103§112 | Non-Final OA | — | Pending | Jan 04, 2024 |
| 18403429 | Methods and Compositions for Treating Diseases Associated with Exhausted T Cells | WOOLWINE, SAMUEL C | 1681 | §102§103§112DP | Non-Final OA | — | Pending | Jan 03, 2024 |
| 18570153 | MATERIAL DEPOSITION ONTO AND RECOVERY FROM SURFACES VIA CONTACTLESS, REVERSIBLE DROPLET WETTING/DE-WETTING BY DIELECTRIC CHARGE INJECTION | SUN, CAITLYN MINGYUN | 1795 | §102 | Non-Final OA | 2d overdue | Pending | Dec 14, 2023 |
| 18569403 | ULTRA-HIGH THROUGHPUT ON-CHIP SYNTHESIS OF MICROGELS WITH TUNABLE MECHANICAL PROPERTIES | NILAND, PATRICK DENNIS | — | §103 | Non-Final OA | — | Pending | Dec 12, 2023 |
| 18567629 | RECOMBINANT ADENO-ASSOCIATED VIRUSES FOR LESCH-NYHAN DISORDERS AND USES THEREOF | GOMEZ RODRIGUEZ, JULIO WASHINGTON | — | §103§112 | Non-Final OA | — | Pending | Dec 06, 2023 |
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Start Free TrialThe Trustees of the University of Pennsylvania has 126 pending office actions as of October 2026, spread across 58 art units and 114 examiners.
Tracy Ann Vivlemore has the most, with 4 of The Trustees of the University of Pennsylvania's pending office actions.
Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.