Prosecution Insights
Prosecution Insights
Technology area: Biotechnology & Pharmaceuticals
118 pending office actions • 95 clients • 110 examiners • 67 art units • 0 of 118 (0%) have an AI response strategy ready
ICE MILLER LLP is a patent law firm specializing in Biotechnology & Pharmaceuticals. The firm has managed 4323 career applications, achieving a resolved allowance rate of 84.13 percent. This volume of filings is supported by an average of 3.23 office actions per allowance. Currently, the firm maintains 85 pending office actions within its primary technology area.
The 84.13 percent allowance rate suggests a consistent success rate for clients in the life sciences sector. Practitioners can expect to navigate approximately 3.23 office actions for each granted patent based on the 4323 career applications handled. This data indicates that while the firm handles a large volume of work, it maintains a steady path to allowance.
With 85 pending office actions, the firm remains active in the Biotechnology & Pharmaceuticals space. This profile reflects a mature practice with significant experience in high-stakes pharmaceutical patenting. The historical performance metrics provide a clear baseline for evaluating the firm's future prosecution efforts.
Based on the USPTO statutory response window for each pending office action. 36 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 36 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 only | 3 (3%) |
| §101 + other | 22 (19%) |
| §103 only | 23 (19%) |
| §102 only | 3 (3%) |
| §112 only | 9 (8%) |
| Double-patenting only | 2 (2%) |
| Double-patenting + other | 14 (12%) |
| Multi-statute (no §101) | 42 (36%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| ZEROUAL, OMAR | 4 | 33.4% | +39.7% |
| HOFFA, ANGELA MARIE | 3 | 67.7% | +28.1% |
| WEDDINGTON, KEVIN E | 2 | 75.2% | +9.8% |
| NEAGU, IRINA | 2 | 46.8% | +57.3% |
| THOMPSON, CURTIS A | 2 | 60.8% | +52.7% |
| DO, NHAT CHIEU Q | 1 | 64.1% | +48.9% |
| NELSON, KERI JESSICA | 1 | 58.5% | +41.2% |
| GARCIA-GUERRA, DARLENE | 1 | 23.2% | +34.4% |
| JACKSON-TONGUE, LAKIA J | 1 | 69.0% | +20.8% |
| SKROBARCZYK III, ROBERT ANTHONY | 1 | 16.7% | +16.3% |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18635402 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | AULAKH, CHARANJIT | 475d overdue |
| 18793346 | SYSTEMS AND METHODS FOR AUTOMATED PREDICTION OF INSIGHTS FOR VENDOR PRODUCT ROADMAPS | ZEROUAL, OMAR | 147d overdue |
| 18729134 | STATISTICAL DATA ACQUISITION DEVICE, DEGREE OF CONTRIBUTION CALCULATION DEVICE, TREATMENT ACTION SEARCH DEVICE, TREATMENT OBJECT SEARCH DEVICE, STATISTICAL DATA ACQUISITION PROGRAM, DEGREE OF CONTRIBUTION CALCULATION PROGRAM, TREATMENT ACTION SEARCH PROGRAM, AND TREATMENT OBJECT SEARCH PROGRAM | LEE, ANDREW ELDRIDGE | 72d overdue |
| 18127221 | DIFFUSER SECURED TO CONTAINER DRAWING OIL FRAGRANCE INTO DIFFUSER ELEMENT VIA CAPILLARY ACTION | PHAM, TUONGMINH NGUYEN | 32d overdue |
| 17756379 | RETAINING DEVICE FOR A URINARY CATHETER AND ASSEMBLY COMPRISING A RETAINING DEVICE WITH A CATHETER | VARGAS, ANNA ELIZABETH | 15d overdue |
| 18494851 | Method of using a handheldable pulling and compressing device for repair of motor vehicle components | KAKARLA, BHASKAR | 9d overdue |
| 18174463 | FIBER ARRAYS | ALABI, OYELEYE A | 8d overdue |
| 19002457 | DATA RESTORE SYSTEM | GUYTON, PHILIP A | 3d overdue |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18793346 | SYSTEMS AND METHODS FOR AUTOMATED PREDICTION OF INSIGHTS FOR VENDOR PRODUCT ROADMAPS | ZEROUAL, OMAR | 147d overdue |
| 18568043 | SAFE USE OF MMP-12 INHIBITOR | NEAGU, IRINA | 9d overdue |
| 18568031 | USE OF MMP INHIBITORS FOR TREATING ACUTE RESPIRATORY DISTRESS SYNDROME | NEAGU, IRINA | 9d overdue |
| 17260000 | USE OF DROPLET SINGLE CELL EPIGENOME PROFILING FOR PATIENT STRATIFICATION | THOMPSON, CURTIS A | 5d overdue |
| 17259992 | USE OF DROPLET SINGLE CELL EPIGENOME PROFILING FOR PATIENT STRATIFICATION | THOMPSON, CURTIS A | 5d overdue |
| 18949952 | SYSTEMS AND METHODS FOR INTEGRATING REAL-TIME BUSINESS INSIGHTS | ZEROUAL, OMAR | 34d |
| 19558117 | HIGH STIFFNESS BOOSTER WITH COMPLIANT SUPPORT TABS AT NODE OR ANTINODE POSITIONS AND ULTRASONIC WELDING APPARATUS INCLUDING SAME | DO, NHAT CHIEU Q | — |
| 19533974 | Frame | NELSON, KERI JESSICA | — |
| Art Unit | Apps |
|---|---|
| 1629 | 5 |
| 3628 | 4 |
| 1621 | 4 |
| 1798 | 3 |
| 3629 | 2 |
| 1627 | 2 |
| 1651 | 2 |
| 1675 | 2 |
| 1797 | 2 |
| 3724 | 1 |
| App # | Title | Client | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|---|
| 19558117 | HIGH STIFFNESS BOOSTER WITH COMPLIANT SUPPORT TABS AT NODE OR ANTINODE POSITIONS AND ULTRASONIC WELDING APPARATUS INCLUDING SAME | Dukane Ias, LLC | DO, NHAT CHIEU Q | 3724 | §102§103§112DP | Final Rejection | — | Pending | Mar 05, 2026 |
| 19533974 | Frame | Mosaic Surgical Limited | NELSON, KERI JESSICA | 3786 | §102§103DPOther | Non-Final OA | — | Pending | Feb 09, 2026 |
| 19399360 | SYSTEMS AND METHODS FOR SUPPLY CHAIN MANAGEMENT INCLUDING ERP AGNOSTIC REALTIME DATA MESH WITH CHANGE DATA CAPTURE | Ingram Micro Inc. | ZEROUAL, OMAR | 3629 | §101§103 | Non-Final OA | — | Pending | Nov 24, 2025 |
| 19294170 | METHOD AND SYSTEM FOR PROVIDING TECHNICAL SERVICE TO AN AGRICULTURAL WORKING MACHINE | Claas Omaha Inc. | GARCIA-GUERRA, DARLENE | §101§103§112 | Non-Final OA | — | Pending | Aug 07, 2025 | |
| 19189410 | COMBINATION USES OF NITROXOLINE AND ITS ANALOGUES WITH CHEMOTHERAPIES AND IMMUNOTHERAPIES IN THE TREATMENT OF CANCERS | Jiangsu Yahong Meditech Co., Ltd. | JACKSON-TONGUE, LAKIA J | §102§103Other | Non-Final OA | — | Pending | Apr 25, 2025 | |
| 19171105 | METHODS OF ENHANCING STEM CELL PRODUCTION | All-Cells Healing, Inc. | SKROBARCZYK III, ROBERT ANTHONY | §101§112 | Non-Final OA | — | Pending | Apr 04, 2025 | |
| 19088739 | METHOD AND SYSTEM OF A COMMAND BUFFER BETWEEN A CPU AND GPU | Oxide Interactive, Inc. | HSU, JONI | §103Other | Non-Final OA | — | Pending | Mar 24, 2025 | |
| 19085265 | METHODS TO TREAT LONG-COVID AND INFLUENZA | Tesla Biohealing, LLC | HOFFA, ANGELA MARIE | §101§112 | Non-Final OA | — | Pending | Mar 20, 2025 | |
| 19043212 | METHODS TO TREAT GENE MUTATION AND MUSCULAR DEGENERATIVE DISEASE | All-Cells Healing Inc. | HOFFA, ANGELA MARIE | §101§112 | Non-Final OA | — | Pending | Jan 31, 2025 | |
| 19043248 | METHODS TO TREAT PARKINSON'S DISEASE | Brain Healing Inc. | HOFFA, ANGELA MARIE | §101§112 | Non-Final OA | — | Pending | Jan 31, 2025 | |
| 19009885 | METHODS TO MITIGATE SIDE EFFECTS OF CANCER TREATMENTS | All-Cells Healing Inc. | SISON, CHRISTINE ANDREA PAN | §101§112 | Non-Final OA | — | Pending | Jan 03, 2025 | |
| 18880475 | COMBINATION THERAPIES INVOLVING L-ASPARAGINASE | Jazz Pharmaceuticals Ireland Limited | PAK, YONG D | §102§103§112 | Non-Final OA | — | Pending | Dec 31, 2024 | |
| 19005365 | AUTOMATED MULTI-PARTY DOCUMENT MANAGEMENT PLATFORM AND USER INTERACTIVE TOOL | Citizens Financial Group, Inc. | WALTON, CHESIREE A | 3624 | §101§103 | Non-Final OA | — | Pending | Dec 30, 2024 |
| 19003616 | SYSTEM AND METHOD FOR PAYROLL RECONCILIATION AND PAYMENT | Salus Finance, LLC | NOVAK, REBECCA R | 3629 | §101§103 | Final Rejection | — | Pending | Dec 27, 2024 |
| 19002457 | DATA RESTORE SYSTEM | Druva Inc. | GUYTON, PHILIP A | 2113 | §101 | Non-Final OA | 3d overdue | Pending | Dec 26, 2024 |
| 19000016 | METHOD, A COMPUTER PROGRAM AND A SYSTEM FOR SPERM QUALITY DETERMINATION | Fundació Institut De Ciències Fotòniques | THOMAS, MIA M | §103 | Non-Final OA | — | Pending | Dec 23, 2024 | |
| 18985291 | ANTI-THEFT DEVICE FOR A TRANSPORT RAILCAR GRATING | Holden America Il, LLC | MCCARRY JR, ROBERT J | §102 | Non-Final OA | — | Pending | Dec 18, 2024 | |
| 18971858 | LOW PROFILE HOLLOW RETROREFLECTOR ASSEMBLY AND THEIR MOUNTING STRUCTURES AND MOUNTING METHODS | Plx, Inc. | RAKOWSKI, CARA E | §102§103§112 | Non-Final OA | — | Pending | Dec 06, 2024 | |
| 18949952 | SYSTEMS AND METHODS FOR INTEGRATING REAL-TIME BUSINESS INSIGHTS | Ingram Micro Inc. | ZEROUAL, OMAR | 3628 | §101§103§112 | Final Rejection | 34d | Pending | Nov 15, 2024 |
| 18938440 | GUANIDINOACETIC ACID, ITS DERIVATES, COMPOSITIONS AND METHODS OF USE THEREOF | Christopher Stahley | ARCORIA, PAUL JOSEPH | §103§112 | Non-Final OA | — | Pending | Nov 06, 2024 | |
| 18936975 | LAYERED, OBJECT SPACE, PROGRAMMABLE AND ASYNCHRONOUS SURFACE PROPERTY GENERATION SYSTEM | Oxide Interactive, Inc. | CRAWFORD, JACINTA M | DP | Non-Final OA | — | Pending | Nov 04, 2024 | |
| 18905686 | BRAKE PAD WEAR SENSOR | Sadeca Systems, S.L.U. | AUNG, SAN M | §103 | Non-Final OA | — | Pending | Oct 03, 2024 | |
| 18853244 | IMMUNE ENHANCEMENT OF CANCER TREATMENT | Institut D'Investigacions Biomédiques August Pi I Sunyer (Idibaps) | ABBAS, ABDULRAHMAN MUSTAFA | §103§112 | Non-Final OA | — | Pending | Oct 01, 2024 | |
| 18895049 | THORACOSTOMY DEVICE | Ohiohealth Corporation | MARCETICH, ADAM M | §112DP | Non-Final OA | — | Pending | Sep 24, 2024 | |
| 18828450 | MULTI-MODAL DEVELOPMENT INTERFACE FOR LARGE LANGUAGE MODEL APPLICATIONS | Gopal Datt Joshi | O'CONNOR-EMANUEL, LAWRENCE SCOTT | §101§102§103§112 | Non-Final OA | — | Pending | Sep 09, 2024 | |
| 18844879 | METHOD AND SYSTEM FOR LEAKAGE DETECTION IN A FLUID SYSTEM | Grundfos Holding A/S | BOLDUC, DAVID J | §101§102§103 | Non-Final OA | — | Pending | Sep 06, 2024 | |
| 18843180 | SYSTEM AND METHOD FOR TREATMENT BY ELECTROPHYSIOLOGICAL STIMULATION | TrueRelief, LLC | ALTER MORSCHAUSER, ALYSSA MARGO | §103Other | Non-Final OA | — | Pending | Aug 30, 2024 | |
| 18817538 | SYSTEMS AND METHODS FOR STANDARDIZING DEFINITION OF SOFTWARE ARCHITECTURES | Facets Cloud Inc. | MITCHELL, JASON D | §101§102§103§112 | Non-Final OA | — | Pending | Aug 28, 2024 | |
| 18810352 | LIPID COMPOUND, LIPID NANOPARTICLE COMPRISING SAME AND USE THEREOF | Themedium Therapeutics Co., Ltd. | ARNOLD, ERNST V | §102§103§112DP | Non-Final OA | — | Pending | Aug 20, 2024 | |
| 18794654 | KINETIC CARRIER DEVICE | Degrees Of Freedom LLC | CASTELLANO, STEPHEN J | 3733 | §102§112 | Final Rejection | 62d | Pending | Aug 05, 2024 |
| 18793346 | SYSTEMS AND METHODS FOR AUTOMATED PREDICTION OF INSIGHTS FOR VENDOR PRODUCT ROADMAPS | Ingram Micro Inc. | ZEROUAL, OMAR | 3628 | §101§112 | Final Rejection | 147d overdue | Pending | Aug 02, 2024 |
| 18775244 | ADJUSTABLE FLOW URINARY CATHETER | Rethink Medical, S.L. | LEVY, BRANDON WILLIAM | §102§103§112 | Non-Final OA | — | Pending | Jul 17, 2024 | |
| 18729134 | STATISTICAL DATA ACQUISITION DEVICE, DEGREE OF CONTRIBUTION CALCULATION DEVICE, TREATMENT ACTION SEARCH DEVICE, TREATMENT OBJECT SEARCH DEVICE, STATISTICAL DATA ACQUISITION PROGRAM, DEGREE OF CONTRIBUTION CALCULATION PROGRAM, TREATMENT ACTION SEARCH PROGRAM, AND TREATMENT OBJECT SEARCH PROGRAM | Aizoth Inc. | LEE, ANDREW ELDRIDGE | 3684 | §101§102§103 | Final Rejection | 72d overdue | Pending | Jul 15, 2024 |
| 18768971 | SYSTEMS AND METHODS FOR DISTRIBUTION MANAGEMENT INCLUDING SPECIAL PRICING DETERMINATION | Ingram Micro Inc. | NELSON, FREDA ANN | 3628 | §101§112 | Final Rejection | 60d | Pending | Jul 10, 2024 |
| 18727456 | SILICONE GEL COMPOSITION OF WALNUT EXTRACT | Hartington Business, S. L. | MOEHLMAN, ANDREW TERRY | 1655 | §103§112 | Non-Final OA | — | Pending | Jul 09, 2024 |
| 18752705 | HAND-HELD PULLING AND COMPRESSION DEVICE AND MECHANICAL FORCE AMPLIFIER | Tkr Spezialwerkzeuge GmbH | LONG, ROBERT FRANKLIN | 3731 | §112 | Non-Final OA | — | Pending | Jun 24, 2024 |
| 18752716 | HAND-HELD PULLING AND COMPRESSION DEVICE AND MODULAR SYSTEM | Tkr Spezialwerkzeuge GmbH | SONG, HIMCHAN | §112 | Non-Final OA | — | Pending | Jun 24, 2024 | |
| 18723323 | METHOD AND KIT FOR TREATING A DAMAGED CONNECTIVE TISSUE | Reddress Ltd. | PEEBLES, KATHERINE | 1617 | §103§112DP | Non-Final OA | — | Pending | Jun 21, 2024 |
| 18722532 | RELIABLE OPTICAL TRANSIT TIME METHOD FOR DETERMINING DISTANCE VALUES | K.A. Schmersal Holding GmbH & Co. Kg | WOLDEMARYAM, ASSRES H | §102§103§112 | Non-Final OA | — | Pending | Jun 20, 2024 | |
| 18577053 | SMALL MOLECULE COMPOUND TARGETING BCL9/BETA-CATENIN INTERACTION | Nantong Jutai Biotech Co., Ltd. | KOSTURKO, GEORGE W | §102§103§112 | Non-Final OA | — | Pending | Jun 06, 2024 | |
| 18735463 | BIOENERGY (BIOPHOTON) GENERATOR AND ITS USE | Tesla Biohealing, Inc. | TRUONG, QUANGLONG N | 1615 | §103 | Non-Final OA | — | Pending | Jun 06, 2024 |
| 18716469 | METHOD AND APPARATUS FOR DETECTING HYDRAULIC SHOCK | Grundfos Holding A/S | TIMILSINA, SHARAD | 2853 | §103§112 | Non-Final OA | — | Pending | Jun 04, 2024 |
| 18714054 | HANDHELD PULLING AND COMPRESSING DEVICE | Tkr Spezialwerkzeuge GmbH | WILSON, LEE D | 3723 | §102 | Final Rejection | — | Pending | May 28, 2024 |
| 18712989 | DAROLUTAMIDE PHARMACEUTICAL COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF | Sinotherapeutics Inc. | PARK, HAEJIN S | 1614 | §102§103§112 | Non-Final OA | — | Pending | May 23, 2024 |
| 18711807 | COMPOUNDS AS BCL-2 INHIBITORS | Fochon Biosciences, Ltd. | WILLIS, DOUGLAS M | §102§112DPOther | Final Rejection | — | Pending | May 20, 2024 | |
| 18635402 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | Medic Life Sciences Inc. | AULAKH, CHARANJIT | 1621 | §102§112Other | Non-Final OA | 475d overdue | Pending | Apr 15, 2024 |
| 18701612 | MULTI-LAYERED MATERIAL, IN PARTICULAR FOR HYGIENE/SANITARY PRODUCTS, AND MANUFACTURING METHOD FOR MAKING SUCH A MULTI-LAYERED MATERIAL | Fitesa Sulmona S.r.l. | PHAM, KATHERINE-PH MINH | 3781 | §103§112 | Non-Final OA | — | Pending | Apr 15, 2024 |
| 18697846 | One-Step Method for Synthesis of Circular RNA | Suzhou Abogen Biosciences Co., Ltd. | GROOMS, TIFFANY NICOLE | §102§103§112 | Non-Final OA | — | Pending | Apr 02, 2024 | |
| 18692278 | METHODS OF TREATING CANCER WITH ANTI-HER2 BIPARATOPIC ANTIBODIES | Zymeworks, Inc. | EDGINGTONGIORDANO, FRANCESCA | §103§112Other | Non-Final OA | — | Pending | Mar 14, 2024 | |
| 18599752 | ENHANCED NO-CODE ETL SYSTEM FOR AUTOMATED BIG DATA TRANSFORMATION AND SHARING | Cloudblue LLC | CHOI, YUK TING | 2164 | §103§112 | Non-Final OA | — | Pending | Mar 08, 2024 |
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Start Free Trial84.1% of resolved applications prosecuted by Ice Miller LLP were allowed, across 4,323 applications in USPTO records.
3.23 office actions per allowed application on average.
118 pending office actions as of October 2026, for 95 clients, before 110 examiners in 67 art units.