Prosecution Insights
Last updated: April 19, 2026

Chalker Flores, LLP

87 pending office actions • 57 clients

Portfolio Summary

87
Total Pending OAs
22
Final Rejections
65
Non-Final OAs

Client Portfolio (57 clients)

Client (Assignee)Pending OAs
Texas Tech University System 9
Texas Scottish Rite Hospital For Children 4
Nacuity Pharmaceuticals, Inc. 4
BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 3
La Jolla Institute For Immunology 3
Nacuity Pharmaceuticals, Inc. 2
La Jolla Institute For Immunology 2
Southern Methodist University 2
National University Corporation Tokyo Medical And Dental University 2
Textron Innovations Inc. 2
The Board Of Regents Of The University Of Oklahoma 2
Mayo Foundation for Medical Education and Research 2
AyuVis Research, Inc. 2
University Of North Texas Health Science Center AT Fort Worth 2
Elate Medical, Inc. 1
Vektor Pharma Tf GmbH 1
Iph LLC 1
Korea Advanced Institute Of Science And Technology 1
Evolution Spine, LLC 1
Mata Edu, Inc. 1
Crscube, Inc. 1
The Board Of Regents Of Universtity Of Oklahoma 1
Nanocomposix, Inc. 1
Ross Teggatz 1
University Of Vermont And State Agricultural College 1
Whispergenics. Inc. 1
Innaworks Development Limited 1
Dbp Communications, Inc. 1
Tohoku University 1
Australian Droid & Robot Pty Ltd. 1
China Resources Sanjiu Medical & Pharmaceutical Co., Ltd. 1
Haitang (Jiangsu) Biotechnology Company, Ltd. 1
Npic 1
Vaxdome Inc. 1
Kansas State University Research Foundation 1
Osaka University 1
Natural Polymer International Corporation 1
Evonik Corporation 1
Atems Co., Ltd. 1
University of North Carolina - Chapel Hill 1
UNIVERSITY OF ROCHESTER 1
The Regents of the University of California 1
Toagosei Co., Ltd. 1
Anyon Computing Inc. 1
Arog Pharmaceuticals, Inc. 1
Oklahoma Medical Research Foundation 1
Arcedi Biotech ApS 1
Tianjin Institute Of Pharmaceutical Research Co., Ltd. 1
Ilumi Solutions, Inc. 1
Canbas Co., Ltd. 1
Applied Medical Enzyme Research Institute Corporation 1
University of North Carolina - Chapel Hill 1
Ilumi Solutions, Inc. 1
Your Command, LLC 1
Garmor Inc. 1
TruConsent 1
Coronado Aesthetics, LLC 1

Pending Office Actions

App #TitleClientExaminerArt UnitStatusFiled
18706643 Untitled Elate Medical, Inc. BARRY, DAPHNE MARIE 3753 Non-Final OA
19307513 Sublingual Formulation of Anticancer Compound for Use in the Treatment of Autoimmune Neurodegenerative Diseases Vektor Pharma Tf GmbH GOTFREDSON, GAREN 1619 Final Rejection Aug 22, 2025
19281151 METHOD AND APPARATUS TO PROVIDE AN INTEGRATED UNIFIED HEAT SOURCE FOR CHAFING DISHES Iph LLC KIRKWOOD, SPENCER HAMMETT 3761 Final Rejection Jul 25, 2025
19174635 Externally Magnetically Operated Suture Anchor Texas Scottish Rite Hospital For Children MCGINNITY, JAMES RYAN 3771 Non-Final OA Apr 09, 2025
18985413 Culture conditions for high production of antibiotic compound aureothin from Streptomyces thioluteus Korea Advanced Institute Of Science And Technology SPANGLER, JOSEPH RANKIN 1656 Non-Final OA Dec 18, 2024
18927151 CERVICAL INTERBODY Evolution Spine, LLC LANE, HOLLY JOANNA 3773 Non-Final OA Oct 25, 2024
18887482 Method and System for Generating Solution Explanations for Learning Problems Mata Edu, Inc. UTAMA, ROBERT J 3715 Non-Final OA Sep 17, 2024
18776848 Method and System for Recording Clinical Trial Data Using Generative AI Model Crscube, Inc. ERICKSON, BENNETT S 3683 Final Rejection Jul 18, 2024
18770850 METHOD FOR PREPARATION OF N-ACETYL CYSTEINE AMIDE OR DI- N-ACETYL CYSTEINE AMIDE AND DERIVATIVES Nacuity Pharmaceuticals, Inc. BONAPARTE, AMY C 1692 Final Rejection Jul 12, 2024
18719116 REVERSAL OF SENESCENCE BY ULTRASOUND IRRADIATION BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM CWERN, JONATHAN 3797 Final Rejection Jun 12, 2024
18678550 METHOD FOR PREPARATION OF N-ACETYL CYSTEINE AMIDE OR DI- N-ACETYL CYSTEINE AMIDE AND DERIVATIVES Nacuity Pharmaceuticals, Inc. BONAPARTE, AMY C 1692 Final Rejection May 30, 2024
18670885 Treatment for Skeletal Diseases Caused by Intracellular Protein Trafficking Defects The Board Of Regents Of Universtity Of Oklahoma COPPINS, JANET L 1628 Non-Final OA May 22, 2024
18661787 SILVER NANOPLATE COMPOSITIONS AND METHODS Nanocomposix, Inc. PAK, HANNAH J 1764 Non-Final OA May 13, 2024
18707899 Copper Hydrogel Beads as a Diet Supplement Texas Tech University System JOSEPH, JANET 1611 Non-Final OA May 07, 2024
18628192 Bone Reshaping Tool and Method Texas Scottish Rite Hospital For Children SIPP, AMY R. 3775 Non-Final OA Apr 05, 2024
18628448 Power Converters Using Precise Timing Control Ross Teggatz COX, CASSANDRA F 2849 Non-Final OA Apr 05, 2024
18614071 Fetal Microchimeric Cells and EVs for Regenerative Medicine in Women's Health University Of Vermont And State Agricultural College CLARKE, TRENT R 1651 Non-Final OA Mar 22, 2024
18693693 Triple Drug Combination (Metformin, Simvastatin, Digoxin) for Targeted Treatment of Colorectal Cancer Whispergenics. Inc. GALSTER, SAMUEL LEONARD 1693 Non-Final OA Mar 20, 2024
18692964 In-Situ Hydrogen Generation and Production From Petroleum Reservoirs Texas Tech University System LEMBO, AARON LLOYD 3672 Non-Final OA Mar 18, 2024
18690013 Ergonomic Thumb-Actuable Keyboard Innaworks Development Limited NADKARNI, SARVESH J 2629 Non-Final OA Mar 07, 2024
18597021 Methods of Making Deuterium-Enriched N-Acetylcysteine Amide (D-NACA) and (2R,2R)-3,3-Disulfanediyl BIS(2-Acetamidopropanamide) (DINACA) and Using D-NACA and DINACA to Treat Diseases Involving Oxidative Stress Nacuity Pharmaceuticals, Inc. ROBINSON, MIKHAIL O'DONNEL 1627 Final Rejection Mar 06, 2024
18427115 System and Method for Securing a Document with a Printed Geometric Security Background Dbp Communications, Inc. LEWIS, JUSTIN V 3637 Final Rejection Jan 30, 2024
18539931 AGENT FOR ANTI-AGING OR FOR CELLULAR REJUVENATION Tohoku University BORALSKY, LUKE ALAN 1624 Non-Final OA Dec 14, 2023
18568393 REMOTELY CONTROLLABLE RESCUE VESSEL Australian Droid & Robot Pty Ltd. BURGESS, MARC R 3615 Non-Final OA Dec 08, 2023
18561963 TRADITIONAL CHINESE MEDICINE COMPOSITION FOR INFECTIOUS DISEASE RECOVERY AND USE THEREOF China Resources Sanjiu Medical & Pharmaceutical Co., Ltd. BOECKELMAN, JACOB A 1655 Non-Final OA Nov 17, 2023
18560456 APPLICATION OF ALGINATE OLIGOSACCHARIDES Haitang (Jiangsu) Biotechnology Company, Ltd. BRANDSEN, BENJAMIN MICHAEL 1693 Non-Final OA Nov 13, 2023
18482147 Use of Black Solider Fly Larvae as Palatant / Palatability Enhancer for use in edible pet products Npic KOHLER, STEPHANIE A 1791 Non-Final OA Oct 06, 2023
18470999 Neuraminidase-Inhibited Influenza Virus Vaxdome Inc. FOLEY, SHANON A 1671 Non-Final OA Sep 20, 2023
18468020 Fluorescence Detection of Circulating Cell Free DNA Including Within Extracellular Vesicles in Biospecimens and Liquid Biopsies Kansas State University Research Foundation ALABI, OYELEYE A 1797 Non-Final OA Sep 15, 2023
18550488 SARS-CoV-2 inhibitors - artificial compounds Unknown WHITE, DAWANNA SHAR-DAY 1627 Non-Final OA Sep 14, 2023
18548359 Layered Manganese Oxide, and Preparation Method Thereof Osaka University ROLDAN RAMOS, CHRISTIAN 1723 Non-Final OA Aug 30, 2023
18354164 Hinge-Link Spinal Correction Device and Method Texas Scottish Rite Hospital For Children COMSTOCK, DAVID C 3773 Non-Final OA Jul 18, 2023
18222541 PALATABILITY ENHANCER (PALATANT) COMPOSITION FOR USE IN EDIBLE PET PRODUCTS Natural Polymer International Corporation MCNEIL, JENNIFER C 1793 Final Rejection Jul 17, 2023
18272030 CHIMERIC ANTI-CORONAVIRUS SPIKE PROTEIN ANTIBODIES La Jolla Institute For Immunology GRIZER, CASSANDRA SENN 1672 Non-Final OA Jul 12, 2023
18348811 Ophthalmic Implant Evonik Corporation SCHLIENTZ, LEAH H 1618 Non-Final OA Jul 07, 2023
18347896 Methods of Making Deuterium-Enriched N-Acetylcysteine Amide (D-NACA) and (2R,2R)-3,3-Disulfanediyl BIS(2-Acetamidopropanamide) (DINACA) and Using D-NACA and DINACA to Treat Diseases Involving Oxidative Stress Nacuity Pharmaceuticals, Inc. ROBINSON, MIKHAIL O'DONNEL 1627 Final Rejection Jul 06, 2023
18342881 NONINVASIVE WATER CONTENT SENSOR Southern Methodist University FERDOUS, ZANNATUL 2858 Final Rejection Jun 28, 2023
18333812 METHOD FOR PREPARING INJECTABLE INJECTION COMPOSITION DERIVED FROM ANIMAL CARTILAGE, AND USE THEREOF Atems Co., Ltd. FIEBIG, RUSSELL G 1655 Final Rejection Jun 13, 2023
18256449 BCAA-Lowering Compounds for Prevention and/or Treatment of Alzheimer's Disease and Related Disorders Texas Tech University System LADD, CAROLYN LOUISE 1622 Non-Final OA Jun 08, 2023
18256222 Agent for Preventing or Treating Frontotemporal Lobar Degeneration National University Corporation Tokyo Medical And Dental University AEDER, SEAN E 1642 Non-Final OA Jun 07, 2023
18322942 ANALYSIS OF PROTEIN KINASES IN LIVE CELLS University of North Carolina - Chapel Hill WHITE, ASHLEY TAYLOR 1653 Non-Final OA May 24, 2023
18322187 Method of Treating Cancer With Atpenin A5 Derviatives UNIVERSITY OF ROCHESTER ANDERSON, REBECCA L 1626 Non-Final OA May 23, 2023
18035160 HLA CLASS II-RESTRICTED TCRS AGAINST THE KRAS G12>V ACTIVATING MUTATION The Regents of the University of California GODDARD, LAURA B 1642 Non-Final OA May 03, 2023
18307343 TILTED PROPELLERS FOR ENHANCED DISTRIBUTED PROPULSION CONTROL AUTHORITY Textron Innovations Inc. GREEN, RICHARD R 3647 Non-Final OA Apr 26, 2023
18249988 CARRIER PEPTIDE FRAGMENT AND USE THEREOF Toagosei Co., Ltd. NOAKES, SUZANNE MARIE 1656 Non-Final OA Apr 21, 2023
18137016 DISTRIBUTED MICROWAVE QUANTUM COMPUTING SYSTEM Anyon Computing Inc. HOSSAIN, MOAZZAM 2898 Non-Final OA Apr 20, 2023
18249523 CHIMERIC ANTI-SARS-COV2 NUCLEOPROTEIN ANTIBODIES La Jolla Institute For Immunology BARRERA, IMMACULADA 1671 Non-Final OA Apr 18, 2023
18031800 Coronavirus Spike Glycoprotein With Improved Expression and Stability La Jolla Institute For Immunology JADHAO, SAMADHAN JAISING 1672 Non-Final OA Apr 13, 2023
18296755 EXOSOME ENCODED IL-10 AS A TREATMENT FOR INFLAMMATION ASSOCIATED ADVERSE PREGNANCY CONDITION BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM ABBAS, SYED JARAR 1674 Non-Final OA Apr 06, 2023
18192346 METHOD OF INHIBITING MUTANT C-KIT Arog Pharmaceuticals, Inc. DAHLIN, HEATHER RAQUEL 1629 Non-Final OA Mar 29, 2023
18185780 Method for Synchronous Communication to Procure, Schedule, Coordinate, and Deliver Materials to a Plurality of Construction Projects Automatically Using a Calendar Model Unknown OBAID, HAMZEH M 3624 Non-Final OA Mar 17, 2023
18044149 Inhibition of Endothelial ETS Family Transcription Factors Promotes Flow-Dependent Ocular Vessel Regression Oklahoma Medical Research Foundation HUANG, GIGI GEORGIANA 1613 Non-Final OA Mar 06, 2023
18006300 Flexible Intramedullary Device Tether Texas Scottish Rite Hospital For Children LANE, HOLLY JOANNA 3773 Non-Final OA Jan 20, 2023
18006097 Coronavirus Vaccine Texas Tech University System HILL, MYRON G 1671 Non-Final OA Jan 19, 2023
18004479 Biomarkers for Identifying Relapses in Multiple Sclerosis The Board Of Regents Of The University Of Oklahoma FONTAINHAS, AURORA M 1675 Non-Final OA Jan 06, 2023
18009576 Method for Determining Risk of Pre-Term Birth Arcedi Biotech ApS BORGEEST, CHRISTINA M 1675 Non-Final OA Dec 09, 2022
17923936 Polypeptide Derivative Having Dual Receptor Agonistic Action and Use Thereof Tianjin Institute Of Pharmaceutical Research Co., Ltd. HELLMAN, KRISTINA M 1654 Non-Final OA Nov 08, 2022
17923325 Immune Cell Biomarkers of Cardiovascular Disease La Jolla Institute For Immunology PAULUS, ERIN VIRGINIA 1631 Non-Final OA Nov 04, 2022
17921238 Method for Exchanging and Storing Electronic Keys Ilumi Solutions, Inc. REYNOLDS, DEBORAH J 2400 Non-Final OA Oct 25, 2022
17971072 MICROBIOME TRANSPLANTATION FOR OSTEOARTHRITIS THERAPY The Board Of Regents Of The University Of Oklahoma CRUM, MARY ABOU NADER 1657 Final Rejection Oct 21, 2022
17908999 MODIFIED TETRACYCLINES FOR TREATMENT OF ALCOHOL USE DISORDER, PAIN AND OTHER DISORDERS INVOLVING POTENTIAL INFLAMMATORY PROCESSES Texas Tech University System HOWELL, THEODORE R 1628 Non-Final OA Sep 02, 2022
17861673 IDO/TDO Inhibitor Canbas Co., Ltd. BARSKY, JARED 1628 Final Rejection Jul 11, 2022
17838421 Multimodal Device for Transdermal Treatments Unknown GETZOW, SCOTT M 3792 Non-Final OA Jun 13, 2022
17631934 AGENT FOR PREVENTING OR TREATING MILD COGNITIVE IMPAIRMENT National University Corporation Tokyo Medical And Dental University D' AMBROSIO, THEA 1654 Non-Final OA Jun 07, 2022
17782768 METHOD AND COMPOSITIONS FOR ENGINEERING GRAPEVINE RED BLOTCH VIRUS-RESISTANT GRAPEVINE Texas Tech University System RADOSAVLJEVIC, ALEKSANDAR 1662 Non-Final OA Jun 06, 2022
17777183 Method for Collecting Data for Predicting Occurrence of Anaphylaxis Applied Medical Enzyme Research Institute Corporation FONSECA LOPEZ, FRANCINI ALVARENGA 1685 Non-Final OA May 16, 2022
17776417 Stem Cell Memory T Cells, Methods and Uses for Modulating Inflammatory Responses, and Diagnosing and Treating Adverse Cardiovascular Events and Disease La Jolla Institute For Immunology MONTGOMERY, ANN Y 1678 Non-Final OA May 12, 2022
17741518 ANALYSIS OF PROTEIN KINASES IN LIVE CELLS University of North Carolina - Chapel Hill WHITE, ASHLEY TAYLOR 1653 Non-Final OA May 11, 2022
17768537 Bi-Peptide with Affinity to Extracellular Matrix Proteins or Cells and to Growth Factors for Tissue Healing and Regeneration Mayo Foundation for Medical Education and Research STEELE, AMBER D 1658 Non-Final OA Apr 13, 2022
17591280 CHITIN ANALOGS FOR THE TREATMENT OF KIDNEY DISEASES AyuVis Research, Inc. CRAIGO, BAHAR ALAWI 1699 Final Rejection Feb 02, 2022
17585286 Inhibitors of Multidrug Resistance Transporter P-Glycoprotein Southern Methodist University BAUER, NICOLA MARIA 1621 Non-Final OA Jan 26, 2022
17567400 Wireless Communication Methods Ilumi Solutions, Inc. RENNER, BRANDON M 2411 Non-Final OA Jan 03, 2022
17554782 tRNA-Derived Fragments as Disease Biomarkers and Neuropathological Regulators in Alzheimer's Disease BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM MYERS, CARLA J 1682 Non-Final OA Dec 17, 2021
17525060 COMPOSITIONS AND THERAPEUTIC METHODS AyuVis Research, Inc. BAKSHI, PANCHAM 1623 Non-Final OA Nov 12, 2021
17441990 DIGITAL SUPPLY CHAIN MANAGEMENT SYSTEM Mayo Foundation for Medical Education and Research YU, ARIEL J 3627 Final Rejection Sep 22, 2021
17462414 ROTORCRAFT FALL RESTRAINT PROTECTION ATTACH POINTS AND MECHANISM SYSTEMS Textron Innovations Inc. EDWARDS, LOREN C 3746 Final Rejection Aug 31, 2021
17461812 System, Method and Apparatus for Increasing Website Relevance While Protecting Privacy Your Command, LLC POPHAM, JEFFREY D 2432 Non-Final OA Aug 30, 2021
17361763 Personalized Medicine Approach for Treating Cognitive Loss University Of North Texas Health Science Center AT Fort Worth AKOGYERAM II, NICHOLAS A 3686 Final Rejection Jun 29, 2021
17339652 TREATMENT OF CYSTINOSIS Nacuity Pharmaceuticals, Inc. KWON, JOHN SEUNGJAI 1615 Non-Final OA Jun 04, 2021
17284525 Method to Express, Purify, and Biotinylate Eukaryotic Cell-Derived Major Histocompatibility Complexes Texas Tech University System YAO, LEI 1642 Final Rejection Apr 12, 2021
17275398 Industrial Scale Processes Form a Covalent Bonded Monomer and Graphene Oxide Structures Garmor Inc. FOSS, DAVID ROGER 1764 Final Rejection Mar 11, 2021
17156560 PRODRUG FOR THE TREATMENT OF DISEASE AND INJURY OF OXIDATIVE STRESS Nacuity Pharmaceuticals, Inc. KWON, JOHN SEUNGJAI 1615 Non-Final OA Jan 23, 2021
16307298 Method and Composition For Reducing Pathogens in Pet Food Using Lactic Acid Bacteria Texas Tech University System DAVIS, RUTH A 1699 Final Rejection Apr 13, 2020
16312346 Blood Test for Screening Out Amyloid and Alzheimers Disease Presence University Of North Texas Health Science Center AT Fort Worth CHERNYSHEV, OLGA N 1675 Final Rejection Dec 21, 2018
16310981 Method and Composition for Reducing Pathogens in Rendered Food Products Using Lactic Acid Bacteria Texas Tech University System GOUGH, TIFFANY MAUREEN 1651 Non-Final OA Dec 18, 2018
16035632 SYSTEM AND METHOD FOR CREATING AN ELECTRONIC CONSENT-BASED MEDICAL RECORD TruConsent HOLCOMB, MARK 3685 Non-Final OA Jul 14, 2018
15775712 METHODS OF TREATING SKIN CONDITIONS USING PLASMONIC NANOPARTICLES Coronado Aesthetics, LLC BLAISE, BRADFORD CHRISTOPHER 3794 Non-Final OA May 11, 2018

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