Prosecution Insights
Prosecution Insights
Technology area: Biotechnology & Pharmaceuticals
146 pending office actions • 92 clients • 134 examiners • 69 art units • 0 of 146 (0%) have an AI response strategy ready
Lathrop GPM LLP maintains a practice in the Biotechnology & Pharmaceuticals technology area, with a history of 6785 career applications. The firm achieves a resolved allowance rate of 83.27 percent, indicating the proportion of its cases that successfully reach a grant. This volume of 6785 career applications provides a historical basis for the firm's experience in navigating the requirements of the patent office within the life sciences sector.
The firm's prosecution process involves an average of 3.48 office actions per allowance. This figure represents the typical number of interactions with patent examiners required to reach a grant. Currently, the firm is managing 107 pending office actions, which represents the current volume of its active prosecution docket in the Biotechnology & Pharmaceuticals sector. These 107 pending office actions are fewer than the 6785 career applications on record.
The 83.27 percent allowance rate and the 3.48 office actions per allowance offer specific metrics for evaluating prosecution timelines. The 107 pending office actions show the firm's current focus, while the 6785 career applications document its historical involvement in the field. These figures provide a data-grounded view of the firm's activity and results.
Based on the USPTO statutory response window for each pending office action. 37 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 37 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 only | 3 (2%) |
| §101 + other | 24 (16%) |
| §103 only | 27 (18%) |
| §102 only | 12 (8%) |
| §112 only | 4 (3%) |
| Double-patenting only | 2 (1%) |
| Double-patenting + other | 23 (16%) |
| Multi-statute (no §101) | 50 (34%) |
| No statute on record | 1 (1%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| RAHMANI, NILOOFAR | 4 | 77.5% | -2.9% |
| GUSTILO, ESTELLA M | 3 | 53.6% | +34.5% |
| VANHORN, ABIGAIL LOUISE | 2 | 46.8% | +22.4% |
| POLIAKOVA-GEORGAN, EKATERINA | 2 | 64.0% | +18.0% |
| ZARA, JANE J | 2 | 71.0% | +16.1% |
| MUI, CHRISTINE T | 2 | 78.3% | +19.9% |
| SCHLIENTZ, LEAH H | 2 | 41.9% | +38.5% |
| CRAIG, KAILA ANGELIQUE | 2 | 33.8% | +25.2% |
| HOPPE, EMMA RUTH | 2 | 42.1% | +56.8% |
| NGUYEN, NGHI V | 1 | 53.6% | +50.8% |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17262400 | METHOD FOR PRODUCING FOREIGN ANTIGEN RECEPTOR GENE-INTRODUCED CELL | MIANO, JOSEPH PAUL | 87d overdue |
| 18049724 | COMPLEXES FOR GENE DELETION AND EDITING | LEONARD, ARTHUR S | 11d overdue |
| 18439838 | FUNTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS | STEELE, AMBER D | 9d overdue |
| 18684682 | COMPOSITION COMPRISING PASTEURIZED AKKERMANSIA FOR THE TREATMENT OR PREVENTION OF IBS-RELATED ANXIETY | MOREAU, NASHARA LOUISE | 8d overdue |
| 18252896 | METHOD FOR DETECTING AND/OR QUANTIFYING A METAL ELEMENT IN A BIOLOGICAL LIQUID | GAMBLE JR, RANDALL LEE | 14d |
| 18271112 | MEDIUM FOR CULTURING AND EXPANDING NEPHRON PROGENITOR CELLS, METHOD FOR CULTURING AND EXPANDING NEPHRON PROGENITOR CELLS, AND METHOD FOR PRODUCING RENAL ORGANOIDS | O'NEILL, MARISOL ANN | 21d |
| 18094695 | OLIGONUCLEOTIDES FOR MECP2 MODULATION | DACE DENITO, ALEXANDRA GERALDINE | 22d |
| 18041918 | TRANSFORMABLE PNEUMATIC SOFT STRUCTURES | LEDERER, SARAH B | 30d |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 16998587 | TARGETED FLUORESCENT MARKERS IN COMBINATION WITH A FLEXIBLE PROBE | SCHLIENTZ, LEAH H | 162d overdue |
| 18299304 | THERAPEUTIC RADIOLABELLED CONJUGATES AND THEIR USE IN THERAPY | CRAIG, KAILA ANGELIQUE | 23d overdue |
| 18269668 | CLINICAL LABORATORY AUTOMATION SYSTEM WITH SINGLE CALIBRATOR | MUI, CHRISTINE T | 53d |
| 19568680 | YEAST CELL WALL PARTICLE ENCAPSULATION OF BIODEGRADABLE PRO-PAYLOADS | VANHORN, ABIGAIL LOUISE | — |
| 19395349 | USE OF PASTEURIZED AKKERMANSIA FOR TREATING METABOLIC DISORDERS | NGUYEN, NGHI V | — |
| 18705038 | USE OF A MODIFIED B-CAROTENE KETOLASE (BKT) OR A CORRESPONDING NUCLEIC ACID FOR IMPROVING RESISTANCE TO OXIDATIVE STRESS AND/OR PHOTOINHIBITION OF HOST ORGANISMS, IMPROVING BIOMASS PRODUCTIVITY OF HOST ORGANISMS AND/OR PREVAILING OVER OTHER COMPETING ORGANISMS UPON CULTIVATION IN HIGH LIGHT CONDITIONS | POLIAKOVA-GEORGAN, EKATERINA | — |
| 18639584 | METHODS FOR PRODUCING ANTIBODY-LINKER CONJUGATES | GUSTILO, ESTELLA M | — |
| 18696689 | MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION THERAPY | GUSTILO, ESTELLA M | — |
| Art Unit | Apps |
|---|---|
| 1618 | 6 |
| 1636 | 5 |
| 1654 | 4 |
| 1633 | 4 |
| 1651 | 3 |
| 3685 | 3 |
| 1621 | 3 |
| 1625 | 3 |
| 1635 | 3 |
| 1683 | 3 |
| App # | Title | Client | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|---|
| 19568680 | YEAST CELL WALL PARTICLE ENCAPSULATION OF BIODEGRADABLE PRO-PAYLOADS | UNIVERSITY OF MASSACHUSETTS | VANHORN, ABIGAIL LOUISE | 1636 | §103§112DP | Non-Final OA | — | Pending | Mar 16, 2026 |
| 19395349 | USE OF PASTEURIZED AKKERMANSIA FOR TREATING METABOLIC DISORDERS | Compagnie Gervais Danone | NGUYEN, NGHI V | 1653 | §102Other | Final Rejection | — | Pending | Nov 20, 2025 |
| 19378987 | PORTABLE CONTAINER WITH SIMULTANEOUS COLLAPSIBLE SUPPORT FEET | Packfire, Inc. | CASTELLANO, STEPHEN J | 3733 | §102§103§112 | Final Rejection | — | Pending | Nov 04, 2025 |
| 19355164 | EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITORS | Filamon Ltd. | ESPINOSA, CLAUDIA EDILMA | 1654 | §102 | Non-Final OA | 22d | Pending | Oct 10, 2025 |
| 19354420 | METHODS AND SYSTEMS TO INDUCE REFLECTION BASED ON EMOTIONAL VALENCE | Sequelae, Inc. | O'SHEA, BRENDAN S | 3626 | §101§102§103 | Non-Final OA | — | Pending | Oct 09, 2025 |
| 19325002 | SYSTEM AND DEVICE FOR MAXILLOMANDIBULAR FIXATION | Invisian Medical, LLC | RUIZ MARTIN, LUIS MIGUEL | 3772 | §103 | Final Rejection | — | Pending | Sep 10, 2025 |
| 19321862 | METHODS AND SYSTEMS FOR IMPROVING AN EFFECTIVENESS OF REFLECTION BY AN INDIVIDUAL MEMBER | Sequelae, Inc. | COBANOGLU, DILEK B | 3687 | §101§102§112 | Non-Final OA | — | Pending | Sep 08, 2025 |
| 19301806 | TRAJECTORY VALUE LEARNING FOR AUTONOMOUS SYSTEMS | Waabi Innovation Inc. | NGUYEN, TAN QUANG | DP | Non-Final OA | — | Pending | Aug 15, 2025 | |
| 19287736 | ADAPTIVE AUTO-DRILLING FOR DRILLING APPLICATIONS | Flanders Electric Motor Service, LLC | WLODARSKI, NICHOLAS NMN | 3672 | §101 | Final Rejection | — | Pending | Jul 31, 2025 |
| 19271284 | PHARMACEUTICAL FORMULATIONS FOR SUBCUTANEOUS ADMINISTRATION OF FUROSEMIDE | Scpharmaceuticals Inc. | HUANG, GIGI GEORGIANA | 1613 | §103DP | Non-Final OA | 7d | Pending | Jul 16, 2025 |
| 19269487 | ANTIBODY-DRUG CONJUGATES USING TWO DIFFERENT TYPES OF TOPOISOMERASE I INHIBITORS | Araris Biotech AG | VISHNYAKOVA, ELENA VLADIMIROVNA | 1691 | §103§112DP | Non-Final OA | — | Pending | Jul 15, 2025 |
| 19224021 | USE OF AKKERMANSIA FOR TREATING METABOLIC DISORDERS | Wageningen Universiteit | GOUGH, TIFFANY MAUREEN | 1651 | §101DP | Final Rejection | — | Pending | May 30, 2025 |
| 19222001 | SYSTEMS AND METHODS FOR QUANTIFYING NETWORK QUALITY USING A SCORING MODEL | Cable Television Laboratories, Inc. | HUSSAIN, TAUQIR | §101§103 | Non-Final OA | — | Pending | May 29, 2025 | |
| 19210707 | SYSTEMS AND METHODS FOR AUTOMATICALLY GENERATING A RECORD IN A DIGITAL COMMUNICATION NETWORK | Sequelae, Inc. | LAGOY, KYRA RAND | 3685 | §101§103 | Final Rejection | — | Pending | May 16, 2025 |
| 19174814 | ARTIFICIAL INTELLIGENCE POWERED CHIEF OF STAFF BOT | TransforML Platforms Inc. | FILIPCZYK, MARCIN R | 2153 | §103 | Final Rejection | 23d overdue | Pending | Apr 09, 2025 |
| 19083908 | SYSTEMS AND METHODS FOR SUPPORTING HEALTH-BASED COMMUNICATIONS | Sequelae, Inc. | SIOZOPOULOS, CONSTANTINE B | §101§102 | Non-Final OA | — | Pending | Mar 19, 2025 | |
| 19073684 | SYSTEMS AND METHODS FOR INCENTIVIZING HEALTH-BASED INTERVENTIONS BASED ON INFLUENCE IN A DIGITAL COMMUNICATION NETWORK | Sequelae, Inc. | RASNIC, HUNTER J | 3684 | §101§103§112 | Final Rejection | — | Pending | Mar 07, 2025 |
| 19072084 | METHODS AND SYSTEMS FOR DETERMINING AN INTERVENTION BASED TREATMENT FOR CHRONIC MEDICAL CONDITIONS | Sequelae, Inc. | GARTLAND, SCOTT D | 3685 | §101 | Final Rejection | — | Pending | Mar 06, 2025 |
| 19065033 | METHODS AND SYSTEMS FOR DETERMINING STRESS RESILIENCY | Sequelae, Inc. | SAINT-VIL, EDDY | §101§103 | Non-Final OA | — | Pending | Feb 27, 2025 | |
| 19042537 | SYSTEM AND METHOD FOR A BOOM CRANE WITH AN EXTENSIBLE POWER SOURCE ANCHORED ONLY TO THE FIRST SECTION | Custom Truck One Source, Inc. | CAMPOS JR, JUAN J | §101§112 | Non-Final OA | — | Pending | Jan 31, 2025 | |
| 18980424 | BICYCLOOCTANE KRAS INHIBITORS | Incyte Corporation | RAHMANI, NILOOFAR | §102§112 | Non-Final OA | — | Pending | Dec 13, 2024 | |
| 18949302 | ROAD MAPPING FRAMEWORK | Waabi Innovation Inc. | LIN, JESSICA YIFANG | §102§103 | Non-Final OA | — | Pending | Nov 15, 2024 | |
| 18948416 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHOLOGICAL DISORDERS | Alkermes Pharma Ireland Limited | WARD, PAUL V | §112DP | Non-Final OA | — | Pending | Nov 14, 2024 | |
| 18936436 | SYSTEM AND METHOD FOR PLANK PROCESSING | Shaw Industries Group, Inc. | MUDD, HENRY HOOPER | §102 | Non-Final OA | — | Pending | Nov 04, 2024 | |
| 18925317 | SYSTEMS AND METHODS FOR RECONFIGURABLE COHERENT PON | Cable Television Laboratories, Inc. | PHAN, HANH | §103 | Non-Final OA | — | Pending | Oct 24, 2024 | |
| 18900771 | SYNTHESIS AND COMPOSITION OF PHOTODYNAMIC THERAPEUTIC AGENTS FOR THE TARGETED TREATMENT OF CANCER | On Target Laboratories, Inc. | DICKINSON, PAUL W | 1618 | §101§112 | Non-Final OA | — | Pending | Sep 29, 2024 |
| 18896259 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | BIOAGE LABS, INC. | RAHMANI, NILOOFAR | §112DP | Non-Final OA | — | Pending | Sep 25, 2024 | |
| 18886490 | BALLOON INFLATION SYSTEM AND METHODS | Anagram International, LLC | KASENGE, CHARLES R | 2116 | §102 | Non-Final OA | — | Pending | Sep 16, 2024 |
| 18841615 | SYSTEMS AND METHODS FOR CAPILLARY ISOELECTRIC FOCUSING-MASS SPECTROMETRY (CIEF-MS) ISOELECTRIC POINT (pI) CALIBRATION | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. | WANG, JING | §101§103§112 | Non-Final OA | — | Pending | Aug 26, 2024 | |
| 18839971 | METHOD FOR CHECK MEASUREMENT OF A LOG PROCESSED WITH TREE-HANDLING DEVICE, CORRESPONDING MEASUREMENT SYSTEM, FOREST MACHINE AND HARDWARE | Ponsse Oyj | QUINN, DANIEL MICHAEL | §101§102§103§112 | Non-Final OA | — | Pending | Aug 20, 2024 | |
| 18835285 | AUTONOMOUS SYSTEM TRAINING AND TESTING | Waabi Innovation Inc. | TSWEI, YU-JANG | 2614 | §103 | Final Rejection | 9d | Pending | Aug 01, 2024 |
| 18832725 | LIQUID FORMULATION COMPRISING A FUSION PROTEIN INCLUDING a-GALACTOSIDASE A | Hanmi Pharm. Co., Ltd. | CRAIGO, WILLIAM A | §103§112DP | Non-Final OA | — | Pending | Jul 24, 2024 | |
| 18729403 | HETEROCYCLIC COMPOUNDS AS UBIQUITIN SPECIFIC PROTEASE 7 INHIBITORS | Almac Discovery Limited | HEITMEIER, KENDALL NICOLE | §103§112DP | Non-Final OA | — | Pending | Jul 16, 2024 | |
| 18722680 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SGLT-2 INHIBITOR AND GOSSYPOL | Haim Bio., Ltd. | GALSTER, SAMUEL LEONARD | §103§112 | Non-Final OA | — | Pending | Jun 21, 2024 | |
| 18717580 | VISCERAL SURFACE COVERING SIMULATOR AND METHOD OF USE | Katelyn Marianetti | ANDERSON, BRODERICK C | 2178 | §102§103 | Non-Final OA | — | Pending | Jun 07, 2024 |
| 18717119 | DECORATIVE ARTICLE DELIVERY DEVICE | Shaw Industries Group, Inc. | STABLEY, MICHAEL R | §102§103§112 | Non-Final OA | — | Pending | Jun 06, 2024 | |
| 18715638 | CAPILLARY ELECTROPHORESIS METHODS FOR CHARACTERIZING GENOME INTEGRITY | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. | CHEN, STACY BROWN | §103 | Non-Final OA | — | Pending | May 31, 2024 | |
| 18678931 | TRICYCLIC COMPOUNDS AS INHIBITORS OF KRAS | Incyte Corporation | AULAKH, CHARANJIT | 1621 | §112DP | Final Rejection | — | Pending | May 30, 2024 |
| 18675743 | PYRAZOLOQUINOLINE KRAS INHIBITORS | Incyte Corporation | RAHMANI, NILOOFAR | §102 | Non-Final OA | — | Pending | May 28, 2024 | |
| 18705038 | USE OF A MODIFIED B-CAROTENE KETOLASE (BKT) OR A CORRESPONDING NUCLEIC ACID FOR IMPROVING RESISTANCE TO OXIDATIVE STRESS AND/OR PHOTOINHIBITION OF HOST ORGANISMS, IMPROVING BIOMASS PRODUCTIVITY OF HOST ORGANISMS AND/OR PREVAILING OVER OTHER COMPETING ORGANISMS UPON CULTIVATION IN HIGH LIGHT CONDITIONS | Universita' Degli Studi Di Verona | POLIAKOVA-GEORGAN, EKATERINA | 1651 | §103§112 | Non-Final OA | — | Pending | Apr 26, 2024 |
| 18639584 | METHODS FOR PRODUCING ANTIBODY-LINKER CONJUGATES | Araris Biotech AG | GUSTILO, ESTELLA M | §102Other | Non-Final OA | — | Pending | Apr 18, 2024 | |
| 18638034 | CYCLIC UREA KRAS INHIBITORS | Incyte Corporation | KIFLE, BRUCK | 1624 | §112 | Final Rejection | — | Pending | Apr 17, 2024 |
| 18699825 | TRICYCLIC GPR65 MODULATORS | Pathios Therapeutics Limited | KENYON, JOHN S | 1625 | §112DP | Non-Final OA | — | Pending | Apr 09, 2024 |
| 18698595 | Wound Management Systems | Arthrex, Inc. | STEPHENS, JACQUELINE F | 3781 | §103 | Final Rejection | 12d | Pending | Apr 04, 2024 |
| 18698440 | SOFTWARE FOR MICROFLUIDIC SYSTEMS INTERFACING WITH MASS SPECTROMETRY | Intabio, LLC | NIMOX, RAYMOND LONDALE | §101§103 | Non-Final OA | — | Pending | Apr 04, 2024 | |
| 18696689 | MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION THERAPY | BIONTECH SE | GUSTILO, ESTELLA M | 1646 | §102§103§112Other | Non-Final OA | — | Pending | Mar 28, 2024 |
| 18694663 | MEDICAMENT COMPRISING A P2X4 RECEPTOR ANTAGONIST FOR PREVENTING OR TREATING NOCICEPTIVE PAIN AND/OR VISCERAL PAIN | Nippon Chemiphar Co., Ltd. | RAHMANI, NILOOFAR | 1691 | §102§112 | Non-Final OA | — | Pending | Mar 22, 2024 |
| 18694631 | REGENERATIVE AGENT FOR BONE TISSUE AND LUNG TISSUE, AND PHARMACEUTICAL COMPOSITION FOR REGENERATING BONE TISSUE AND LUNG TISSUE | Niigata University | BERRY, LAYLA D | §102 | Non-Final OA | — | Pending | Mar 22, 2024 | |
| 18611933 | ORAL ROOM-TEMPERATURE STABLE YEAST PARTICLES (YP) AND METHODS OF USE | UNIVERSITY OF MASSACHUSETTS | COHEN, MICHAEL P | 1612 | §103§112 | Non-Final OA | — | Pending | Mar 21, 2024 |
| 18604709 | TRANSGLUTAMINASE CONJUGATION METHOD AND LINKER | Paul Scherrer Institut | XIAO, YAN | §102§112Other | Non-Final OA | — | Pending | Mar 14, 2024 | |
| 18598279 | ANTI-PINCH FOLDABLE TROLLEY | Zhejiang Beihuan Outdoor Products Co., Ltd. | OLSZEWSKI, JOHN | 3617 | §103 | Final Rejection | 17d overdue | Pending | Mar 07, 2024 |
| 18598958 | LIDAR MEMORY BASED SEGMENTATION | Waabi Innovation Inc. | KUAN, JOHN CHUNYANG | §101§112 | Non-Final OA | — | Pending | Mar 07, 2024 | |
| 18688485 | METHODS AND SYSTEMS FOR ASSESSING A QUALITY OF MASS ANALYSIS DATA GENERATED BY A MASS SPECTROMETER | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. | KORANG-BEHESHTI, YOSSEF | §101§102§103§112 | Non-Final OA | — | Pending | Mar 01, 2024 | |
| 18684682 | COMPOSITION COMPRISING PASTEURIZED AKKERMANSIA FOR THE TREATMENT OR PREVENTION OF IBS-RELATED ANXIETY | The Akkermansia Company | MOREAU, NASHARA LOUISE | 1655 | §101§102§103§112 | Non-Final OA | 8d overdue | Pending | Feb 18, 2024 |
| 18684454 | COMBINATION OF A NURR1 AGONIST WITH AT LEAST ONE OF AN ALDOSTERONE ANTAGONIST, AN INSULIN MODULATOR AND A SULFONYLUREA | Genesis Pharma SA | BEANE, RANDALL L | §102§103§112 | Non-Final OA | — | Pending | Feb 16, 2024 | |
| 18439838 | FUNTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS | Ratio Therapeutics, Inc. | STEELE, AMBER D | 1658 | §102§103 | Final Rejection | 9d overdue | Pending | Feb 13, 2024 |
| 18439034 | STABILIZATION OF OLIGONUCLEOTIDE AND OLIGONUCLEOTIDE-PROTEIN COMPLEX USING ALKYLATED PHOSPHATE | UNIVERSITY OF MASSACHUSETTS | MCINTOSH III, TRAVISS C | §102§112 | Non-Final OA | — | Pending | Feb 12, 2024 | |
| 18439235 | Biological Fluid Concentration Devices and Methods of Use | Arthrex, Inc. | BERA, HENA RAKESHKUMAR | 1779 | §103 | Final Rejection | — | Pending | Feb 12, 2024 |
| 18682626 | LIPIDATED POLYMYXIN ANALOGUES | Auckland UniServices Limited | KATAKAM, SUDHAKAR | §103§112 | Non-Final OA | — | Pending | Feb 09, 2024 | |
| 18291808 | LIPID NANOPARTICLE FORMULATIONS | Monash University | WERTZ, ASHLEE ELIZABETH | 1612 | §102§103§112 | Non-Final OA | — | Pending | Jan 24, 2024 |
| 18421647 | MODIFIED OLIGONUCLEOTIDES TARGETING SNPs | UNIVERSITY OF MASSACHUSETTS | WHITEMAN, BRIAN A | 1636 | §102§103§112DP | Non-Final OA | — | Pending | Jan 24, 2024 |
| 18396613 | BRANCHED OLIGONUCLEOTIDES | UNIVERSITY OF MASSACHUSETTS | ZARA, JANE J | 1635 | §103§112DP | Non-Final OA | — | Pending | Dec 26, 2023 |
| 18572622 | IRRADIATION OF GRAIN OR SEEDS | Animal Control Technologies (Australia) Pty Ltd. | BECKER, DREW E | 1792 | §103§112 | Final Rejection | 56d | Pending | Dec 20, 2023 |
| 18571782 | MULTIRESIDUAL METHOD FOR DETECTING AND/OR QUANTIFYING AMINO ACIDS, ORGANIC ACIDS AND/OR MODIFIED NUCLEOTIDES BY MEANS OF HILIC CHROMATOGRAPHIC SEPARATION AND MS/MS | Crescendo Care S.r.l. | MUI, CHRISTINE T | 2855 | §112 | Non-Final OA | — | Pending | Dec 19, 2023 |
| 18570745 | CRISPR CASCADE | The Board Of Trustees Of The University Of Illinois | BAUSCH, SARAE L | 1683 | §102§103§112 | Non-Final OA | — | Pending | Dec 15, 2023 |
| 18570201 | MARKER FOR DNA DAMAGE IN PROXIMITY OF TRANSCRIBED GENOMIC LOCI AND METHODS FOR IDENTIFYING AND/OR QUANTIFYING THESE DNA DAMAGES | Fondazione Istituto Italiano Di Tecnologia | HANEY, AMANDA MARIE | 1682 | §101§112 | Final Rejection | — | Pending | Dec 14, 2023 |
| 18570257 | COMBINATION DOSAGE REGIME OF CD137 AND PD-L1 BINDING AGENTS | BIONTECH SE | METCALF, MATTHEW CURRAN | §103§112DP | Non-Final OA | — | Pending | Dec 14, 2023 | |
| 18569859 | COMPOSITION COMPRISING DRY EXTRACT OF LYOPHILISED INTESTINAL CONTENT OF ADULT CHICKEN, RELATIVE USE AS FOOD SUPPLEMENT AND USE FOR STIMULATING THE IMMUNE SYSTEM | Orbiotek Sàrl | TURNER, FELICIA C | 1793 | §103 | Final Rejection | — | Pending | Dec 13, 2023 |
| 18568418 | METHOD AND APPARATUS FOR FORMING A MICROFLUIDIC GEL STRUCTURE | Mimetas B.V. | ALABI, OYELEYE A | 1633 | §103§112 | Non-Final OA | — | Pending | Dec 08, 2023 |
| 18568747 | METHOD AND COMPOSITIONS FOR NEURONAL REPROGRAMMING | The Governing Council of the University of Toronto | BERTOGLIO, VALARIE E | 1632 | §102§103 | Non-Final OA | — | Pending | Dec 08, 2023 |
| 18568398 | Bioanalysis Workflow with Direct Ejection from Phase-Separated Samples | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. | SINES, BRIAN J | §103§112 | Final Rejection | — | Pending | Dec 08, 2023 | |
| 18568410 | Direct Sampling from Phase-Separated Sample for Hydrophobicity Assessment | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. | MASKELL, MICHAEL P | 2881 | §102§103§112 | Non-Final OA | — | Pending | Dec 08, 2023 |
| 18566868 | INFORMATION PROCESSING DEVICE, INFORMATION PROCESSING METHOD, AND STORAGE MEDIUM | Riken | LI, SUN M | §101§112 | Non-Final OA | — | Pending | Dec 04, 2023 | |
| 18565575 | GENE EDITING SYSTEMS COMPRISING AN RNA GUIDE TARGETING HYDROXYACID OXIDASE 1 (HAO1) AND USES THEREOF | Arbor Biotechnologies, Inc. | ZARA, JANE J | §112 | Non-Final OA | — | Pending | Nov 30, 2023 | |
| 18522928 | MODULAR PORTABLE POWER SYSTEM FOR SMALL APPLIANCE APPLICATIONS | Bollinger Industries, Inc. | MIKELS, MATTHEW | §102 | Non-Final OA | — | Pending | Nov 29, 2023 | |
| 18562090 | ENZYME-CONJUGATED MAGNETIC BEADS SUSPENDED IN INTERNAL STANDARD BUFFER | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. | MONTGOMERY, ANN Y | §103 | Non-Final OA | — | Pending | Nov 17, 2023 | |
| 18561645 | COATING SYSTEM FOR PROTECTING A SUBSTRATE | BEDIMENSIONAL S.P.A. | AHMED, SHEEBA | 1787 | §103 | Final Rejection | 34d | Pending | Nov 16, 2023 |
| 18507340 | NEGATIVE PRESSURE DRAINAGE SYSTEM | Shenzhen Bao'An People'S Hospital | YANG, CHENG FONG | 3781 | §102 | Non-Final OA | — | Pending | Nov 13, 2023 |
| 18503353 | SYSTEM AND METHODS FOR GENOMICS-EHR INTEGRATION | Leap Of Faith Technologies, Inc. | PATEL, SHERYL GOPAL | 3685 | §103 | Final Rejection | — | Pending | Nov 07, 2023 |
| 18501729 | COMBINATION THERAPY COMPRISING A MAT2A INHIBITOR AND A TYPE II PRMT INHIBITOR | Ideaya Biosciences, Inc. | HUTTER, GILLIAN A | 1625 | §103DP | Non-Final OA | 8d overdue | Pending | Nov 03, 2023 |
| 18492635 | PROBABILISTIC MULTI-PARTY AUDIO TRANSLATION | Mass Luminosity, Inc. | MEIS, JON CHRISTOPHER | 2654 | §103 | Non-Final OA | 27d | Pending | Oct 23, 2023 |
| 18556577 | RADIOACTIVE ANTITUMOR AGENT | Nihon Medi-Physics Co., Ltd. | SCHLIENTZ, LEAH H | 1618 | §103 | Non-Final OA | — | Pending | Oct 20, 2023 |
| 18556260 | COMPOUNDS | Pathios Therapeutics Limited | OTTON, ALICIA L | 1699 | §102§112 | Non-Final OA | — | Pending | Oct 19, 2023 |
| 18489682 | W/O/W MICROEMULSIONS FOR OCULAR ADMINISTRATION | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | VANHORN, ABIGAIL LOUISE | §101§103§112DP | Non-Final OA | — | Pending | Oct 18, 2023 | |
| 18380871 | CONJUGATES OF SIRNA AND ANTISENSE OLIGONUCLEOTIDES (SIRNASO) AND METHODS OF USE IN GENE SILENCING | UNIVERSITY OF MASSACHUSETTS | POLIAKOVA-GEORGAN, EKATERINA | 1637 | §102§103§112 | Non-Final OA | — | Pending | Oct 17, 2023 |
| 18555058 | COMBINATION THERAPY COMPRISING A PKC INHIBITOR AND A MEK INHIBITOR | Pfizer, Inc. | O DELL, DAVID K | 1621 | §103 | Non-Final OA | 5d | Pending | Oct 12, 2023 |
| 18286072 | NOVEL FAMILY OF DNA POLYMERASES ACCEPTING 2-AMINOADENINE AND REJECTING ADENINE IN THEIR SUBSTRATES | COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES | REGA, KYLE THOMAS | 1636 | §112Other | Non-Final OA | — | Pending | Oct 06, 2023 |
| 18283367 | SYSTEMS AND METHODS FOR HUMIDITY AND/OR TEMPERATURE CONTROL IN A SAMPLE ANALYSIS SYSTEM | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. | NGUYEN, HENRY H | 1758 | §103 | Final Rejection | — | Pending | Sep 21, 2023 |
| 18368488 | MOTION FORECASTING FOR AUTONOMOUS SYSTEMS | Waabi Innovation Inc. | ANYIKIRE, CHIKAODILI E | §102§103 | Non-Final OA | — | Pending | Sep 14, 2023 | |
| 18281722 | System and Method for Variable FFT Analysis Windows in Mass Spectrometry | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. | CHOI, JAMES J | 2878 | §103 | Non-Final OA | — | Pending | Sep 12, 2023 |
| 18463837 | DE NOVO ENGINEERING OF A BACTERIAL LIFESTYLE PROGRAM | The Board Of Trustees Of The University Of Illinois | WARD, AARON DUREL | 1636 | §103 | Non-Final OA | — | Pending | Sep 08, 2023 |
| 18549454 | SYSTEMS AND METHODS FOR THE PREPARATION OF ENRICHED SERUM | Arthrex, Inc. | LYLE, SOPHIA YUAN | 1796 | §103§112 | Non-Final OA | — | Pending | Sep 07, 2023 |
| 18453098 | FCRN BINDING POLYPEPTIDES | The Board Of Trustees Of The University Of Illinois | GUSTILO, ESTELLA M | 1646 | §102§103§112 | Non-Final OA | — | Pending | Aug 21, 2023 |
| 18277211 | ROBOTIC SYSTEM MODELLING | United Kingdom Atomic Energy Authority | HOANG, SON T | §101§102§112 | Non-Final OA | — | Pending | Aug 14, 2023 | |
| 18276762 | BODY TEMPERATURE LOWERING AGENT, BODY TEMPERATURE ELEVATION SUPPRESSOR, FOOD COMPOSITION FOR LOWERING BODY TEMPERATURE,AND FOOD COMPOSITION FOR SUPPRESSING BODY TEMPERATURE ELEVATION | UNIVERSITY OF TSUKUBA | ROZOF, TIMOTHY R | 1625 | §102 | Final Rejection | 56d | Pending | Aug 10, 2023 |
| 18361156 | MODULAR MULTI-PANEL SOLAR CELL | 4D Vision Corp. | CANNON, RYAN SMITH | 1726 | §102 | Non-Final OA | 114d overdue | Pending | Jul 28, 2023 |
| 18274624 | METHOD AND MEANS FOR MODULATING B-CELL MEDIATED IMMUNE RESPONSES | UNIVERSITAET ULM | NICKOL, GARY B | 1643 | §101§102§112DP | Non-Final OA | — | Pending | Jul 27, 2023 |
| 18226834 | YEAST PARTICLES FOR DELIVERY OF WATER-ACTIVATED SELF-EMULSIFYING CANNABINOID FORMULATIONS | UNIVERSITY OF MASSACHUSETTS | SCOTLAND, REBECCA LYNN | 1791 | §102§103§112DP | Non-Final OA | — | Pending | Jul 27, 2023 |
| 18274605 | METHOD AND MEANS FOR MODULATING B-CELL MEDIATED IMMUNE RESPONSES | UNIVERSITAET ULM | CHANDRA, GYAN | 1674 | §102§103§112 | Non-Final OA | — | Pending | Jul 27, 2023 |
| 18271660 | MARKER FOR ASSISTING IN DIAGNOSIS OF NEPHROTIC SYNDROME AND USE THEREOF | Niigata University | NGUYEN, NAM P | 1678 | §101§103§112 | Final Rejection | — | Pending | Jul 10, 2023 |
| 18349606 | FUSED TRICYCLIC COMPOUNDS AS INHIBITORS OF KRAS G12V MUTANTS | Incyte Corporation | DEKARSKE, MADELINE MCGUIRE | 1622 | §103Other | Final Rejection | 46d | Pending | Jul 10, 2023 |
| 18271112 | MEDIUM FOR CULTURING AND EXPANDING NEPHRON PROGENITOR CELLS, METHOD FOR CULTURING AND EXPANDING NEPHRON PROGENITOR CELLS, AND METHOD FOR PRODUCING RENAL ORGANOIDS | Rege Nephro Co., Ltd. | O'NEILL, MARISOL ANN | 1633 | §102§103§112 | Final Rejection | 21d | Pending | Jul 06, 2023 |
| 18341210 | BOYSENBERRY COMPOSITIONS AND METHODS OF PREPARATION AND USE THEREOF | The New Zealand Institute for Plant and Food Research Limited | VISONE, THOMAS J | 1672 | DPOther | Non-Final OA | 70d | Pending | Jun 26, 2023 |
| 18269668 | CLINICAL LABORATORY AUTOMATION SYSTEM WITH SINGLE CALIBRATOR | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. | MUI, CHRISTINE T | 1797 | §102§103 | Final Rejection | 53d | Pending | Jun 26, 2023 |
| 18213505 | MODIFIED GUIDE RNAS FOR CRISPR GENOME EDITING | UNIVERSITY OF MASSACHUSETTS | KONOPKA, CATHERINE ANNE | 1635 | §103§112 | Non-Final OA | — | Pending | Jun 23, 2023 |
| 18255420 | PRODUCTION OF FUNGAL BIOMASS | Mushlabs GmbH | ARIANI, KADE | 1651 | — | Final Rejection | 17d overdue | Pending | Jun 01, 2023 |
| 18038653 | BIOMOLECULE STRUCTURE DETECTION PROBE, BIOMOLECULE STRUCTURE DETECTION KIT, AND METHOD FOR DETECTING BIOMOLECULE STRUCTURE | Kyushu University, National University Corporation | LUSI, ELLIS FOLLETT | 1677 | §102 | Final Rejection | — | Pending | May 24, 2023 |
| 18197670 | USE OF LEUKEMIA-DERIVED CELLS FOR ENHANCING NATURAL KILLER (NK) CELL THERAPY | Mendus B.V. | LARA, CAROLINE MONSERRAT | 1633 | §103 | Non-Final OA | 92d overdue | Pending | May 15, 2023 |
| 18252896 | METHOD FOR DETECTING AND/OR QUANTIFYING A METAL ELEMENT IN A BIOLOGICAL LIQUID | Cardiovascular Lab S.r.l. | GAMBLE JR, RANDALL LEE | 1795 | §103§112 | Final Rejection | 14d | Pending | May 15, 2023 |
| 18036144 | FUSION PROTEIN TARGETING BOTH CD3 AND CD137, PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING IMMUNOAH PHARMATECH CO., LTD. | MOSELEY II, NELSON B | 1642 | §103§112 | Non-Final OA | — | Pending | May 09, 2023 |
| 18035766 | COMPOSITION COMPRISING AKKERMANSIA MUCINIPHILA AND GREEN TEA EXTRACT | The Akkermansia Company | DEVI, SARVAMANGALA | 1645 | §103§112 | Final Rejection | — | Pending | May 08, 2023 |
| 18251493 | A PROCESS FOR PRODUCING EGF | Chemical & Biopharmaceutical Laboratories Of Patras S.A. | DABKOWSKI, ERINNE R | 1654 | §103§112 | Non-Final OA | — | Pending | May 02, 2023 |
| 18140908 | SELECTIVE RNA-MODULATING AGENTS | UNIVERSITY OF MASSACHUSETTS | GROOMS, TIFFANY NICOLE | 1637 | §103§112DP | Non-Final OA | — | Pending | Apr 28, 2023 |
| 18303346 | COPPER COMPLEXES FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | Als Therapy Development Institute | SABILA, MERCY HELLEN | 1654 | §103§112DP | Non-Final OA | 60d overdue | Pending | Apr 19, 2023 |
| 18299344 | ARTIFICIAL INTELLIGENCE HEALTH DIAGNOSTIC SYSTEM AND METHOD | Evan Greebel | AKOGYERAM II, NICHOLAS A | 3686 | §101 | Final Rejection | 70d | Pending | Apr 12, 2023 |
| 18299304 | THERAPEUTIC RADIOLABELLED CONJUGATES AND THEIR USE IN THERAPY | University Of Sydney | CRAIG, KAILA ANGELIQUE | 1618 | §103DP | Final Rejection | 23d overdue | Pending | Apr 12, 2023 |
| 18193958 | METHODS OF TREATING ENHANCING BRAIN TUMORS USING COMBINATION THERAPY | Servier Pharmaceuticals Llc. | HAMA, JOANNE | 1647 | §103Other | Non-Final OA | 23d overdue | Pending | Mar 31, 2023 |
| 18027306 | METHOD FOR PREPARING EFFECTOR CELLS WITH DESIRED SPECIFICITY | National University Corporation Shiga University Of Medical Science | ZHU, JIANJIAN | 1631 | §103§112DP | Final Rejection | 2d overdue | Pending | Mar 20, 2023 |
| 18043075 | SYSTEMS FOR CAPTURING CELLS | Arthrex, Inc. | TOWA, RENE T | 3791 | §102§103 | Final Rejection | — | Pending | Feb 27, 2023 |
| 18041918 | TRANSFORMABLE PNEUMATIC SOFT STRUCTURES | Massachusetts Institute Of Technology | LEDERER, SARAH B | 3785 | §103§112 | Final Rejection | 30d | Pending | Feb 16, 2023 |
| 18107292 | MULTISPECIFIC BINDING PROTEINS TARGETING CEA | Dragonfly Therapeutics, Inc. | HUYNH, PHUONG N | 1641 | §103§112 | Non-Final OA | — | Pending | Feb 08, 2023 |
| 18094695 | OLIGONUCLEOTIDES FOR MECP2 MODULATION | UNIVERSITY OF MASSACHUSETTS | DACE DENITO, ALEXANDRA GERALDINE | 1636 | §103§112 | Final Rejection | 22d | Pending | Jan 09, 2023 |
| 18091651 | DEVICES AND METHODS FOR SAMPLE CHARACTERIZATION | Intabio, LLC | CHIU, TAK LIANG | 1777 | §103 | Non-Final OA | 23d overdue | Pending | Dec 30, 2022 |
| 18010197 | MEANS AND METHODS FOR CLASSIFYING MICROBES | Université De Lausanne | ELKINS, BLAKE HARRISON | 1687 | §101§102§103§112 | Non-Final OA | — | Pending | Dec 13, 2022 |
| 18009142 | ISOTHERMAL REAL-TIME PCR METHOD FOR DETERMINING PRESENCE OF A PRE-DETERMINED NUCLEIC ACID SEQUENCE IN HUMAN SAMPLES | Certus Molecular Diagnostics AG | HOPPE, EMMA RUTH | 1683 | §102§103§112Other | Final Rejection | — | Pending | Dec 08, 2022 |
| 18008809 | ISOTHERMAL REAL-TIME PCR METHOD FOR DETERMINING PRESENCE OF A PRE-DETERMINED NUCLEIC ACID SEQUENCE OF A BACTERIUM OF THE MOLLICUTES CLASS IN A SAMPLE | Certus Molecular Diagnostics AG | HOPPE, EMMA RUTH | 1683 | §103§112Other | Final Rejection | — | Pending | Dec 07, 2022 |
| 18071590 | THERMODYNAMIC MEASURES ON PROTEIN-PROTEIN INTERACTION NETWORKS FOR CANCER THERAPY | Csts Health Care Inc. | ROSSI, VY BUI | §101§103§112DP | Non-Final OA | — | Pending | Nov 29, 2022 | |
| 18058059 | ANTI-VIRAL DRY CLEANING PROCESS | Greenearth Cleaning, LLC | YOO, REGINA M | 1758 | §103§112 | Final Rejection | — | Pending | Nov 22, 2022 |
| 17999001 | N-(PHENYLAMINOCARBONYL) TETRAHYDRO-ISOQUINOLINES AND RELATED COMPOUNDS AS MODULATORS OF GPR65 | Pathios Therapeutics Limited | BAUER, NICOLA MARIA | 1621 | §103DPOther | Final Rejection | 36d overdue | Pending | Nov 16, 2022 |
| 17999013 | METHODS OF TREATING OR PREVENTING ORGANOPHOSPHORUS POISONING | Lachesis Biosciences Limited | HIRAKIS, SOPHIA P | 1623 | §103DP | Final Rejection | — | Pending | Nov 16, 2022 |
| 17998574 | POLYNUCLEOTIDES COMPRISING AN ANTIGENIC PAYLOAD | Nutcracker Therapeutics, Inc. | DENT, ALANA HARRIS | 1643 | §102§103§112 | Non-Final OA | — | Pending | Nov 11, 2022 |
| 18049724 | COMPLEXES FOR GENE DELETION AND EDITING | UNIVERSITY OF MASSACHUSETTS | LEONARD, ARTHUR S | 1631 | §103§112 | Final Rejection | 11d overdue | Pending | Oct 26, 2022 |
| 17920881 | MICROFLUIDIC DEVICES WITH GAS CHANNELS FOR SAMPLE NEBULIZATION | Intabio, LLC | GOURLIE, LAURA ELOISE | 2881 | §103§112 | Non-Final OA | — | Pending | Oct 24, 2022 |
| 17940636 | VIRAL GUIDE RNA DELIVERY | BEAM THERAPEUTICS INC. | DHAR, MATASHA | 1632 | §103 | Final Rejection | — | Pending | Sep 08, 2022 |
| 17760329 | USP7 INHIBITOR FOR USE IN THE TREATMENT OF CANCER | Almac Discovery Limited | REILLY, SOPHIA JANE | 1627 | §103 | Final Rejection | 22d | Pending | Aug 08, 2022 |
| 17769657 | METHOD FOR PRODUCING RADIOACTIVE METAL-LABELED ANTIBODY | Nihon Medi-Physics Co., Ltd. | JONES, DAMERON LEVEST | 1618 | §103§112Other | Non-Final OA | — | Pending | Apr 15, 2022 |
| 17624690 | COMBINATION | Genesis Pharma SA | D' AMBROSIO, THEA | 1654 | §102§112Other | Non-Final OA | 55d | Pending | Jan 04, 2022 |
| 17599282 | XYLOGLUCAN-CONTAINING PRODRUGS AND METHODS OF MANUFACTURE AND USE THEREOF | The Governors of the University of Alberta | HIBSHMAN, SARAH GRACE | 1693 | §103 | Non-Final OA | — | Pending | Sep 28, 2021 |
| 17262400 | METHOD FOR PRODUCING FOREIGN ANTIGEN RECEPTOR GENE-INTRODUCED CELL | National University Corporation Shiga University Of Medical Science | MIANO, JOSEPH PAUL | 1631 | §102§103§112Other | Non-Final OA | 87d overdue | Pending | Aug 27, 2021 |
| 17429754 | PLASMA POLYMER NANOPARTICLES CARRYING AGENTS | The Heart Research Institute Ltd. | PATTERSON, SARAH COOPER | 1675 | DP | Final Rejection | — | Pending | Aug 10, 2021 |
| 17415842 | ULTRASOUND CONTRAST AGENT AND METHODS FOR USE THEREOF | GE Healthcare AS | CRAIG, KAILA ANGELIQUE | 1618 | §103§112 | Non-Final OA | — | Pending | Jun 18, 2021 |
| 17285356 | INTEIN PROTEINS AND USES THEREOF | Fondazione Telethon | GU, QINHUA | 1633 | §103§112 | Final Rejection | — | Pending | Apr 14, 2021 |
| 16999759 | O-METHYL RICH FULLY STABILIZED OLIGONUCLEOTIDES | UNIVERSITY OF MASSACHUSETTS | ARIETI, RUTH SOPHIA | 1635 | §103DPOther | Non-Final OA | — | Pending | Aug 21, 2020 |
| 16998587 | TARGETED FLUORESCENT MARKERS IN COMBINATION WITH A FLEXIBLE PROBE | On Target Laboratories, LLC | SCHLIENTZ, LEAH H | 1618 | §103 | Final Rejection | 162d overdue | Pending | Aug 20, 2020 |
| 15555811 | MICROPARTICLES | Spheritech Ltd. | LOVE, TREVOR M | 1611 | §102DP | Final Rejection | 11d overdue | Pending | Sep 05, 2017 |
| 14390495 | KETONE BODIES AND KETONE BODY ESTERS FOR MAINTAINING OR IMPROVING MUSCLE POWER OUTPUT | Tdeltas Limited | LEE, WILLIAM Y | 1623 | §103Other | Non-Final OA | — | Pending | Oct 03, 2014 |
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