Prosecution Insights
Prosecution Insights
Technology area: Biotechnology & Pharmaceuticals
177 pending office actions • 100 clients • 174 examiners • 132 art units • 0 of 177 (0%) have an AI response strategy ready
HAMILTON, BROOK, SMITH & REYNOLDS, P.C. manages 12553 career applications, primarily in Biotechnology & Pharmaceuticals. The firm has a resolved allowance rate_pct of 77.6. Prosecution requires an avg_office_actions_per_allowance of 3.85, suggesting a persistent prosecution style necessary for complex biotech patents.
The firm currently has 146 pending office actions. With a large portfolio of 12553 career applications, the 77.6 allowance rate is a significant indicator of their performance in the life sciences. The 3.85 office actions per allowance reflects the iterative nature of examination in the Biotechnology & Pharmaceuticals sector. For practitioners, these metrics highlight a firm with extensive experience and a consistent ability to navigate the challenges of biotech patent prosecution over a very large number of cases.
Based on the USPTO statutory response window for each pending office action. 55 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 55 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 only | 6 (3%) |
| §101 + other | 20 (11%) |
| §103 only | 57 (32%) |
| §102 only | 10 (6%) |
| §112 only | 8 (5%) |
| Double-patenting only | 1 (1%) |
| Double-patenting + other | 9 (5%) |
| Multi-statute (no §101) | 63 (36%) |
| No statute on record | 3 (2%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| SANG, HONG | 3 | 55.0% | +62.6% |
| WOZNICKI, JACQUELINE | 2 | 49.8% | +26.1% |
| HRANEK, KAREN AMANDA | 1 | 34.4% | +39.9% |
| TOLEDO-DURAN, EDWIN J | 1 | 70.2% | +32.0% |
| BECK, LERON | 1 | 80.3% | +10.8% |
| JEAN GILLES, JUDE | 1 | 92.8% | +2.5% |
| HOLLOMAN, NANNETTE | 1 | 60.7% | +23.2% |
| HOSSAIN, KAMAL M | 1 | 81.4% | +26.6% |
| WOOD, KIMBERLY T | 1 | 54.8% | +27.6% |
| VASISTH, VISHAL V | 1 | 72.5% | +33.5% |
Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 2 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 19182761 | Automatic Discovery and Reporting of Streaming Content of Interest and Connection of User to Same | JEAN GILLES, JUDE | — |
| 19073801 | Scalable Offloading of Computer Vision Processing Tasks | HOSSAIN, KAMAL M | — |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17730897 | Performing A Deformation-Based Physics Simulation | HAO, YI | 190d overdue |
| 18328682 | ADJUNCTIVE THERAPY FOR DEPRESSION | CHONG, YONG SOO | 121d overdue |
| 17758847 | Inhibitors of Glucose-6-phosphate Dehydrogenase and Uses Thereof | ANDERSON, REBECCA L | 107d overdue |
| 17780961 | BIOMASS-BASED SOLID COMPOSITE ELECTROLYTES FOR BATTERIES | NGUYEN, KEVIN NMN | 56d overdue |
| 18753908 | Method And Apparatus For Wireless Communications | ARMSTRONG, JONATHAN D | 36d overdue |
| 17594150 | System and Method for Improving a Processing System using Learning Systems | KNIGHT, PAUL M | 24d overdue |
| 18608851 | Sensor, System and Method for Detecting or Sensing Moisture or Wetness of an Article | FERDOUS, ZANNATUL | 19d overdue |
| 17820662 | SOLID-STATE ELECTROLYTE, CATHODE ELECTRODE, AND METHODS OF MAKING SAME FOR SULFIDE-BASED ALL-SOLID-STATE-BATTERIES | VAN KIRK, DUSTIN KENWOOD | 18d overdue |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18175345 | Methods of Treating High Risk Multiple Myeloma | SANG, HONG | 10d overdue |
| 16797301 | Methods of Treating Newly Diagnosed Multiple Myeloma with a Combination of An Antibody that Specifically Binds CD38, Lenalidomide and Dexamethasone | SANG, HONG | 4d overdue |
| 19418900 | METHODS OF TREATING HIGH RISK MULTIPLE MYELOMA | SANG, HONG | — |
| 19331792 | Methods And Systems For Assessing Cumulative Ergonomic Risk | HRANEK, KAREN AMANDA | — |
| 19281549 | Dam with Contaminants Entombing Cap | TOLEDO-DURAN, EDWIN J | — |
| 19126030 | CALIBRATION OF A CAMERA COORDINATE SYSTEM | BECK, LERON | — |
| 19088128 | Pharmaceutical Formulation | HOLLOMAN, NANNETTE | — |
| 19073801 | Scalable Offloading of Computer Vision Processing Tasks | HOSSAIN, KAMAL M | — |
| Art Unit | Apps |
|---|---|
| 1646 | 4 |
| 3774 | 3 |
| 1625 | 3 |
| 3791 | 3 |
| 1653 | 3 |
| 1632 | 3 |
| 1654 | 3 |
| 3684 | 2 |
| 3678 | 2 |
| 2444 | 2 |
| App # | Title | Client | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|---|
| 19418900 | METHODS OF TREATING HIGH RISK MULTIPLE MYELOMA | Janssen Biotech, Inc. | SANG, HONG | 1646 | §102§103§112 | Final Rejection | — | Pending | Dec 12, 2025 |
| 19331792 | Methods And Systems For Assessing Cumulative Ergonomic Risk | Dassault Systems Americas Corp. | HRANEK, KAREN AMANDA | 3684 | §101§103 | Non-Final OA | — | Pending | Sep 17, 2025 |
| 19281549 | Dam with Contaminants Entombing Cap | W.L. French Hydropower Holdings LLC | TOLEDO-DURAN, EDWIN J | 3678 | §102§103§112 | Final Rejection | — | Pending | Jul 25, 2025 |
| 19126030 | CALIBRATION OF A CAMERA COORDINATE SYSTEM | Smart Eye AB | BECK, LERON | 2487 | §103§112 | Non-Final OA | — | Pending | Apr 30, 2025 |
| 19182761 | Automatic Discovery and Reporting of Streaming Content of Interest and Connection of User to Same | Openexchange, Inc. | JEAN GILLES, JUDE | 2459 | §112DP | Non-Final OA | — | Pending | Apr 18, 2025 |
| 19088128 | Pharmaceutical Formulation | Klaria Pharma Holding AB | HOLLOMAN, NANNETTE | 1612 | §102§103§112DP | Non-Final OA | — | Pending | Mar 24, 2025 |
| 19073801 | Scalable Offloading of Computer Vision Processing Tasks | Politecnico Di Torino | HOSSAIN, KAMAL M | 2444 | §102 | Non-Final OA | — | Pending | Mar 07, 2025 |
| 19073852 | Cupholder and Phone Mounting System for a Golf Bag | Gramse Engineering LLC | WOOD, KIMBERLY T | 3631 | §103 | Non-Final OA | — | Pending | Mar 07, 2025 |
| 19108603 | MWW-STRUCTURED MOLECULAR SIEVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Petrochina Company Limited | VASISTH, VISHAL V | 1771 | §103§112DP | Non-Final OA | — | Pending | Mar 04, 2025 |
| 19106975 | IMAGE PROCESSING DEVICE AND METHOD USING ARTIFICIAL NEURAL NETWORK MODEL | Korea Advanced Institute Of Science And Technology | MAUPIN, HUGH H | 2884 | §102 | Non-Final OA | — | Pending | Feb 26, 2025 |
| 19061060 | Systems and Methods for Determining Properties of a Wellbore | DASSAULT SYSTEMES | N'DURE, AMIE MERCEDES | 3645 | §103 | Non-Final OA | — | Pending | Feb 24, 2025 |
| 19043414 | MODULAR HYDROPOWER SYSTEMS AND METHODS WITH PUMPED STORAGE | W.L. French Hydropower Holdings LLC | NGUYEN, VIET P | 2834 | §103 | Final Rejection | 87d overdue | Pending | Feb 01, 2025 |
| 19016629 | Series Enabled Multi-Material Extrusion Technology | Mosaic Manufacturing Ltd. | KIM, YUNJU | 1742 | §102§103 | Final Rejection | — | Pending | Jan 10, 2025 |
| 18986503 | RNA Synthesis-Phosphoramidites for Synthetic RNA in the Reverse Direction, and Application in Convenient Introduction of Ligands, Chromophores and Modifications of Synthetic RNA at the 3'-End | Chemgenes Corporation | DIAMOND, ALAN D | 3991 | §112Other | Non-Final OA | — | Pending | Dec 18, 2024 |
| 18983952 | Medication Adherence Device And Coordinated Care Platform | Watchrx, Inc. | BLANCHETTE, JOSHUA B | 3684 | §101§103 | Non-Final OA | 40d | Pending | Dec 17, 2024 |
| 18961377 | MODULAR PRECAST PUMPED STORAGE HYDRO SYSTEM FOR POWER GENERATION | W.L. French Hydropower Holdings LLC | FIORELLO, BENJAMIN F | 3678 | §102§103 | Non-Final OA | — | Pending | Nov 26, 2024 |
| 18869143 | Systems and Methods for Endoluminal Tracking with Therapeutic Delivery Sensing | Frond Medical Inc. | KIM, KAITLYN EUNJI | 3797 | §102§103 | Non-Final OA | — | Pending | Nov 25, 2024 |
| 18869129 | METHODS AND SYSTEMS FOR IMAGING INTERACTIONS BETWEEN PARTICLES AND FRAGMENTS | UNIVERSITY OF MASSACHUSETTS | NAH, JONGBONG | 2674 | §103 | Non-Final OA | — | Pending | Nov 25, 2024 |
| 18933478 | System and Method for Manipulating Deformable Objects | Northeastern University | OH, HARRY Y | 3657 | §103§112 | Final Rejection | 22d | Pending | Oct 31, 2024 |
| 18932157 | Generating, interpreting and adapting a 3D learning environment using ANNs | Labster Aps | SAINT-VIL, EDDY | 3715 | §101§103 | Non-Final OA | — | Pending | Oct 30, 2024 |
| 18923237 | SYSTEMS AND METHODS FOR NETWORK CONTROL | Granite Telecommunications, LLC | ALRIYASHI, ABDULKADER MOHAMED | 2447 | §103Other | Non-Final OA | 37d overdue | Pending | Oct 22, 2024 |
| 18856983 | PROCESS AND DEVICE FOR ASSEMBLY OF VAN DER WAALS HETEROSTRUCTURES | The University of Manchester | SWIER, WAYNE K. | 1748 | §102§103 | Non-Final OA | — | Pending | Oct 15, 2024 |
| 18909800 | Excitation source system and first device for managing backscatter interference | Koninklijke Kpn N.V. | KUNTZ, CURTIS A | 2646 | §103§112 | Non-Final OA | — | Pending | Oct 08, 2024 |
| 18908040 | METHOD AND SYSTEM FOR PERCEIVING TRAFFIC ROAD ENVIRONMENT BASED ON GRAPH REPRESENTATION FOR AUTONOMOUS DRIVING | Korea Advanced Institute Of Science And Technology | PARK, EDWARD | 2675 | §102§103 | Non-Final OA | — | Pending | Oct 07, 2024 |
| 18905753 | DELIVERY SYSTEM FOR PLACEMENT OF ENDOLUMINAL DEVICES | Frond Medical Inc. | COCHRAN, KARI LEE | 3774 | §102§103 | Non-Final OA | — | Pending | Oct 03, 2024 |
| 18851207 | Wearable Holding Device for Neural Implant Headpiece | Wyss Center For Bio And Neuro Engineering | CIRULNICK, EMILY NICOLE | 3792 | §103 | Final Rejection | — | Pending | Sep 26, 2024 |
| 18898619 | System And Method For Joint Dynamic Forwarding And Caching In Content Distribution Networks | California Institute Of Technology | DOAN, HIEN VAN | 2449 | §103 | Final Rejection | — | Pending | Sep 26, 2024 |
| 18844869 | Vehicular Edge Intelligence in Unlicensed Spectrum Bands | Politecnico Di Torino | AFRIN, NAZIA | 3666 | §103 | Non-Final OA | — | Pending | Sep 06, 2024 |
| 18842756 | Fast Well Plate Differential Scanning Micro-Calorimeter Using Photonic Sensors | The Charles Stark Draper Laboratory, Inc. | LIN, ERICA S Y | 2853 | §102§103 | Non-Final OA | — | Pending | Aug 29, 2024 |
| 18841813 | Expeditionary Shelter Systems | Northeastern University | HIJAZ, OMAR F | 3635 | §103 | Non-Final OA | — | Pending | Aug 27, 2024 |
| 18837581 | Method and Apparatus for Mineral Extraction | The University of Manchester | MENON, KRISHNAN S | 1771 | §102§103§112 | Non-Final OA | — | Pending | Aug 09, 2024 |
| 18782621 | CDK9 Inhibitors and Polymorphs Thereof For Use As Agents For Treatment of Cancer | Sumitomo Pharma Co., Ltd. | ROZOF, TIMOTHY R | 1625 | §102DP | Non-Final OA | — | Pending | Jul 24, 2024 |
| 18778572 | Distributed System with Fault Tolerance and Self-Maintenance | Hyannis Port Research, Inc. | BEYEN, ZEWDU A | 2461 | §103 | Non-Final OA | — | Pending | Jul 19, 2024 |
| 18773960 | Droplet Assembly Method | Oxford University Innovation Limited | KASS, BENJAMIN JOSEPH | 1798 | §103§112 | Non-Final OA | — | Pending | Jul 16, 2024 |
| 18772083 | Two stage plating for reduced Ni and NiO layer formation | Menlo Microsystems, Inc. | DUMBRIS, SETH M | 1787 | §102§103 | Final Rejection | — | Pending | Jul 12, 2024 |
| 18771839 | Combination Therapies with Anti-CD38 Antibodies | Janssen Biotech, Inc. | ALSOMAIRY, SARAH ABDOALATIF | 1646 | §103DP | Non-Final OA | — | Pending | Jul 12, 2024 |
| 18770438 | Smart Eyewear Vision Correction and Adjustment Method and System | Plenoptika, Inc. | STANFORD, CHRISTOPHER J | 2872 | §102§103§112 | Final Rejection | — | Pending | Jul 11, 2024 |
| 18758924 | Compositions And Methods Targeting G12 Signaling For Bronchodilator Therapy | Rutgers, The State University Of New Jersey | COUGHLIN, MATTHEW P | 1626 | §103Other | Final Rejection | 13d | Pending | Jun 28, 2024 |
| 18759313 | ENGINEERED ACID ALPHA-GLUCOSIDASE VARIANTS | Crosswalk Therapeutics, Inc. | CHOWDHURY, IQBAL HOSSAIN | 1656 | §102§112 | Non-Final OA | — | Pending | Jun 28, 2024 |
| 18724306 | ZERO DWELL TIME PROCESS MONITORING | Virsec Systems, Inc. | SHAUGHNESSY, AIDAN EDWARD | 2432 | §102 | Non-Final OA | — | Pending | Jun 26, 2024 |
| 18753908 | Method And Apparatus For Wireless Communications | Northeastern University | ARMSTRONG, JONATHAN D | 3645 | §102§103 | Final Rejection | 36d overdue | Pending | Jun 25, 2024 |
| 18720067 | Zero Trust File Integrity Protection | Virsec Systems, Inc. | KANAAN, SIMON P | 2407 | §102 | Final Rejection | — | Pending | Jun 14, 2024 |
| 18719359 | Memory Hybrid-Dynamic Vulnerability Assessment | Virsec Systems, Inc. | MUNGUIA, DUILIO | 2497 | §103 | Final Rejection | 100d overdue | Pending | Jun 13, 2024 |
| 18738572 | SYSTEMS AND METHODS FOR STORING A DATAFILE | Dassault Systèmes Americas Corp. | VUONG, CAO DANG | 2153 | §102§103 | Non-Final OA | — | Pending | Jun 10, 2024 |
| 18717878 | SALT OF 3,4-DIHYDROISOQUINOLINE COMPOUND AND USE THEREOF | Cspc Zhongqi Pharmaceutical Technology(Shijiazhuang) Co., Ltd. | VISHNYAKOVA, ELENA VLADIMIROVNA | 1691 | §103DP | Non-Final OA | — | Pending | Jun 07, 2024 |
| 18715474 | JOINT USE OF MULTIPLE WIRELESS RECEIVERS TO SUPPORT MORE DEMANDING DOWNLINK QUALITY-OF-SERVICE REQUIREMENTS | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | RAHMAN, SHAH M | 2413 | §102§103 | Final Rejection | — | Pending | May 31, 2024 |
| 18714985 | ESTABLISHING LOCAL CONNECTIVITY BETWEEN DEVICES AND APPLICATIONS IN PRIVATE CLOUD ENVIRONMENT | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | CHANG, JUNGWON | 2472 | §112 | Non-Final OA | — | Pending | May 30, 2024 |
| 18714827 | SYSTEM AND METHOD FOR TELEMETRY DATA BASED EVENT OCCURRENCE ANALYSIS WITH ADAPTIVE RULE FILTER | Virsec Systems, Inc. | CHRISTENSEN, SCOTT B | 2444 | §103§112 | Final Rejection | — | Pending | May 30, 2024 |
| 18714839 | USE OF BIFIDOBACTERIUM LACTIS BL-99 IN PREVENTION AND/OR AMELIORATION OF GASTRITIS | Inner Mongolia Dairy Tech Res Institute Co. Ltd. | CRUM, MARY ABOU NADER | 1651 | §103§112DP | Final Rejection | 16d overdue | Pending | May 30, 2024 |
| 18711862 | A SOLAR CELL MODULE AND A SOLAR CELL PANEL | Epishine AB | TRAN, UYEN M | 1726 | §103 | Non-Final OA | — | Pending | May 20, 2024 |
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Start Free Trial77.6% of resolved applications prosecuted by Hamilton, Brook, Smith & Reynolds, P.C. were allowed, across 12,555 applications in USPTO records.
3.85 office actions per allowed application on average.
177 pending office actions as of October 2026, for 100 clients, before 174 examiners in 132 art units.