Prosecution Insights
Prosecution Insights
378 pending office actions • 253 clients • 313 examiners • 132 art units • 0 of 378 (0%) have an AI response strategy ready • 373 patents granted in the last 365 days
Based on the USPTO statutory response window for each pending office action. 191 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 191 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 only | 7 (2%) |
| §101 + other | 54 (14%) |
| §103 only | 107 (28%) |
| §102 only | 7 (2%) |
| §112 only | 32 (8%) |
| Double-patenting only | 18 (5%) |
| Double-patenting + other | 33 (9%) |
| Multi-statute (no §101) | 114 (30%) |
| No statute on record | 6 (2%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| LEE, WILLIAM Y | 9 | 48.2% | +34.0% |
| GIAMMONA, FRANCESCA FILIPPA | 4 | 37.0% | +55.9% |
| NOLAN, JASON MICHAEL | 4 | 66.3% | -28.0% |
| HUANG, GIGI GEORGIANA | 4 | 31.7% | +30.6% |
| GONZALEZ, LUISALBERTO | 3 | 60.7% | +45.5% |
| CASH, KAILEY ELIZABETH | 3 | 29.4% | +57.6% |
| SCHLOOP, ALLISON ELIZABETH | 3 | 60.0% | +59.3% |
| MISIASZEK, AMBER ALTSCHUL | 2 | 47.0% | +24.5% |
| SISSON, BRADLEY L | 2 | 19.7% | +20.6% |
| FRITH, SEAN A | 2 | 62.3% | +26.7% |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17497373 | TISSUE GRASPING DEVICES AND RELATED METHODS | PRONE, CHRISTOPHER D | 169d overdue |
| 17841267 | COMBINATIONS OF FLAVIVIRUS PROTEINS, PEPTIDE SEQUENCES, EPITOPES, AND METHODS AND USES THEREOF | CHEN, STACY BROWN | 154d overdue |
| 18254433 | METHODS FOR CLASSIFICATION OF LIVER DISEASE | HOPPE, EMMA RUTH | 146d overdue |
| 18188315 | COMPOSITIONS AND METHODS FOR GENETIC MODIFICATION AND TARGETING | WILSON, MICHAEL C | 133d overdue |
| 17963651 | SYSTEMS AND METHODS FOR ACCESS MANAGEMENT AND CLUSTERING OF GENOMIC, PHENOTYPE, AND DIAGNOSTIC DATA | MISIASZEK, AMBER ALTSCHUL | 111d overdue |
| 18251817 | SPECIFIC SUBSTRATES AND PRODUCTS OF HSD17B13 AS MARKERS OF LIVER DISEASE AND BIOMARKERS FOR LIVER DISEASE TREATMENT | MISHRA, DEEPA | 81d overdue |
| 17291580 | TWO-GENE VECTORS FOR GENERATING CAR-T CELLS AND USES THEREOF | AEDER, SEAN E | 80d overdue |
| 18483933 | AEROSOL SAMPLE COLLECTION DEVICE | BALAJI, KAVYA SHOBANA | 79d overdue |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17963651 | SYSTEMS AND METHODS FOR ACCESS MANAGEMENT AND CLUSTERING OF GENOMIC, PHENOTYPE, AND DIAGNOSTIC DATA | MISIASZEK, AMBER ALTSCHUL | 111d overdue |
| 17739526 | GENE EXPRESSION SIGNATURE OF ENDOMETRIAL SAMPLES FROM WOMEN WITH AND WITHOUT ENDOMETRIOSIS | CASH, KAILEY ELIZABETH | 32d overdue |
| 18313146 | METHODS FOR DETECTION OF NUCLEOTIDE MODIFICATION | GIAMMONA, FRANCESCA FILIPPA | 30d overdue |
| 18784718 | OPHTHALMIC COMPOSITION | LEE, WILLIAM Y | 10d overdue |
| 18114469 | ORAL PHARMACEUTICAL COMPOSITION COMPRISING ZONISAMIDE AND PROCESS OF PREPARATION THEREOF | HUANG, GIGI GEORGIANA | 10d overdue |
| 17554181 | SYSTEMS FOR SAMPLE ANALYSIS | GIAMMONA, FRANCESCA FILIPPA | 3d overdue |
| 18125474 | COMPOSITIONS AND METHODS FOR REDUCING GREENHOUSE GAS | LEE, WILLIAM Y | 8d |
| 19205483 | SYSTEMS AND METHODS FOR ENDOSCOPE LOCALIZATION | FRITH, SEAN A | 28d |
| Art Unit | Apps |
|---|---|
| 1623 | 16 |
| 3791 | 12 |
| 1683 | 10 |
| 1682 | 9 |
| 1626 | 9 |
| 1627 | 8 |
| 3783 | 8 |
| 1681 | 7 |
| 1631 | 7 |
| 1798 | 7 |
| App # | Title | Client | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|---|
| 19552942 | USE OF 5-HYDROXYMETHYCYTOSINE OR 5-METHYLCYTOSINE FOR DISEASE DETECTION | Biomodal Limited | WILDER, CYNTHIA B | 1681 | §101§103§112 | Non-Final OA | — | Pending | Feb 27, 2026 |
| 19370240 | COMPOSITIONS AND METHODS FOR TREATING ACUTE RESPIRATORY DISTRESS SYNDROME | Direct Biologics, LLC | NIEBAUER, RONALD T | 1658 | §102§103§112DP | Non-Final OA | — | Pending | Oct 27, 2025 |
| 19330712 | SENSOR-BASED MACHINE LEARNING IN A HEALTH PREDICTION ENVIRONMENT | Evidation Health, Inc. | MISIASZEK, AMBER ALTSCHUL | 3682 | §101§103 | Final Rejection | 71d | Pending | Sep 16, 2025 |
| 19305279 | AUGMENTED LEARNING MODEL FOR AUTONOMOUS EARTH-MOVING VEHICLES | Aim Intelligent Machines, Inc. | CHEUNG, CALVIN K | 3669 | DP | Non-Final OA | — | Pending | Aug 20, 2025 |
| 19303223 | PERSONALIZED WELLNESS SYSTEMS AND METHODS OF USE | Onikoroshi, LLC | KRIANGCHAIVECH, KETTIP | 1686 | §101§103Other | Non-Final OA | 30d overdue | Pending | Aug 18, 2025 |
| 19303233 | PERSONALIZED WELLNESS SYSTEMS AND METHODS OF USE | Onikoroshi, LLC | WHALEY, PABLO S | 3619 | §101§103§112Other | Final Rejection | 22d | Pending | Aug 18, 2025 |
| 19292383 | SENSORY GAMMA STIMULATION THERAPY IMPROVES SLEEP QUALITY AND MAINTAINS FUNCTIONAL ABILITY IN ALZHEIMERS DISEASE PATIENTS | Cognito Therapeutics, Inc. | MATTHEWS, CHRISTINE HOPKINS | 3791 | §103§112 | Final Rejection | 46d | Pending | Aug 06, 2025 |
| 19236732 | METHODS, COMPOSITONS AND SYSTEMS FOR ANALYTE DETECTION | Stellaromics, Inc. | SISSON, BRADLEY L | 1682 | §103§112Other | Final Rejection | 40d | Pending | Jun 12, 2025 |
| 19236720 | METHODS, COMPOSITONS AND SYSTEMS FOR ANALYTE DETECTION | Stellaromics, Inc. | SISSON, BRADLEY L | 1682 | §103 | Final Rejection | — | Pending | Jun 12, 2025 |
| 19232420 | DOUBLE BLIND WINE TASTING | Cliink LLC | EL-HAGE HASSAN, ABDALLAH A | §101 | Non-Final OA | — | Pending | Jun 09, 2025 | |
| 19214187 | MAGNETIC CAPTURE DEVICE | Lo Biosciences, Inc. | MIANO, JOSEPH PAUL | 1631 | §103DP | Non-Final OA | — | Pending | May 21, 2025 |
| 19211711 | MULTISPACE PARKING PAY STATIONS INCLUDING PAYMENT IMPROVEMENTS | Ips Group Inc. | VANDERHORST, MARIA VICTORIA | §101§103 | Non-Final OA | — | Pending | May 19, 2025 | |
| 19210753 | METHODS FOR TREATING PROSTATE CANCER WITH RADIOPHARMACEUTICALS | Artbio, Inc. | PERREIRA, MELISSA JEAN | 1618 | §103 | Final Rejection | 2d overdue | Pending | May 16, 2025 |
| 19205483 | SYSTEMS AND METHODS FOR ENDOSCOPE LOCALIZATION | Noah Medical Corporation | FRITH, SEAN A | 3798 | §102§103§112 | Non-Final OA | 28d | Pending | May 12, 2025 |
| 19199682 | Methods and Systems for Evaluation of Lupus Based on Ancestry-Associated Molecular Pathways | Ampel Biosolutions, LLC | PAULSON, SHEETAL R. | 3615 | §101§102 | Final Rejection | — | Pending | May 06, 2025 |
| 19196360 | SYSTEMS AND METHODS FOR MEDICAL IMAGING GATEWAYS | Alara Imaging Inc. | HUANG, KAYLEE J | §101§102§103§112Other | Non-Final OA | — | Pending | May 01, 2025 | |
| 19187780 | METHODS AND SYSTEMS FOR VERIFYING ANTI-TAMPERING OF DATA | Fin3 Technologies, Inc. | ZHANG, DUAN | 3699 | §103 | Non-Final OA | 3d overdue | Pending | Apr 23, 2025 |
| 19184633 | SYSTEMS, METHODS, SOFTWARE, AND PLATFORMS FOR CLINICAL DECISION SUPPORT | Triaj, Inc. | EDOUARD, PATRICIA KELLY | 3683 | §101§103§112 | Non-Final OA | — | Pending | Apr 21, 2025 |
| 19183502 | Fully Automatic Instrument System for Biochemical Assays | Alamar Biosciences, Inc. | THOMPSON, CURTIS A | 1798 | §103 | Final Rejection | 1d overdue | Pending | Apr 18, 2025 |
| 19082681 | SYSTEMS AND METHODS FOR ROBOTIC ENDOSCOPE SYSTEM UTILIZING TOMOSYNTHESIS AND AUGMENTED FLUOROSCOPY | Noah Medical Corporation | LUU, TIMOTHY TUAN | §103 | Non-Final OA | — | Pending | Mar 18, 2025 | |
| 19067593 | TEMPORARY VASCULAR SCAFFOLD AND SCORING DEVICE | Nfinium Vascular Technologies, LLC | RWEGO, KANKINDI | 3771 | §112Other | Non-Final OA | — | Pending | Feb 28, 2025 |
| 19061677 | METHODS AND SYSTEMS FOR GENERATIVE QUESTION ANSWERING FOR CONSTRUCTION PROJECT DATA | Trunk Tools, Inc. | GALVIN-SIEBENALER, PAUL MICHAEL | 2147 | §101§103 | Non-Final OA | — | Pending | Feb 24, 2025 |
| 19056045 | COMPOSITIONS AND METHODS FOR NUCLEIC ACID MODIFICATIONS | Acrigen Biosciences | RYAN, DOUGLAS CHARLES | 1635 | §103Other | Final Rejection | 8d overdue | Pending | Feb 18, 2025 |
| 19054472 | SYSTEMS AND METHODS FOR WASTEWATER HEAT RECOVERY | Epic Cleantec Inc. | ARANT, HARRY E | 3763 | §103 | Non-Final OA | 82d | Pending | Feb 14, 2025 |
| 19053053 | SYSTEMS AND METHODS FOR NUTRIGENOMICS AND NUTRIGENETIC ANALYSIS | Cipher Genetics, Inc. | VANNI, GEORGE STEVEN | 1686 | §101§103§112Other | Final Rejection | 17d overdue | Pending | Feb 13, 2025 |
| 19051350 | INTEGRATED SECURITY FOR CLOUD APPLICATIONS | Slashnext, Inc. | DO, KHANG D | DP | Non-Final OA | — | Pending | Feb 12, 2025 | |
| 19038117 | METHODS AND SYSTEMS FOR REMOTE OPERATION OF VEHICLE | Rotor Technologies, Inc. | HOLWERDA, STEPHEN | 3656 | §101§102§112 | Non-Final OA | — | Pending | Jan 27, 2025 |
| 19030518 | AMORPHOUS (A-POLYMORPHIC) PSILOCYBIN | Diamond Therapeutics Inc. | GONZALEZ, LUISALBERTO | 1624 | §103 | Final Rejection | — | Pending | Jan 17, 2025 |
| 19030061 | COMPOSITIONS AND METHODS FOR PRODUCING FOOD PRODUCTS WITH RECOMBINANT ANIMAL PROTEIN | Bond Pet Foods, Inc. | ROBINSON, HOPE A | 1652 | §112 | Non-Final OA | — | Pending | Jan 17, 2025 |
| 19025546 | SYSTEMS AND METHODS FOR DETERMINING DATABASE PERMISSIONS | Datawalk Spólka Akcyjna | SKHOUN, HICHAM | 2164 | §102§103Other | Final Rejection | 52d overdue | Pending | Jan 16, 2025 |
| 19025976 | METHODS OF USE FOR AZA-QUINAZOLINE COMPOUNDS | Iambic Therapeutics, Inc. | FETTEROLF, BRANDON J | 1626 | §112Other | Non-Final OA | 43d overdue | Pending | Jan 16, 2025 |
| 18992908 | WASTEWATER PROCESSING SYSTEMS AND METHODS | Eniswaterpure, LLC | VARMA, AKASH K | 1773 | §103 | Final Rejection | — | Pending | Jan 09, 2025 |
| 19005188 | FOLDABLE CONNECTING STRUCTURE FOR BED FRAME | Zinus Inc. | ADEBOYEJO, IFEOLU A | 3679 | §103 | Non-Final OA | 18d overdue | Pending | Dec 30, 2024 |
| 19003243 | EARLY DETECTION TOOLS FOR MENTAL HEALTH | Pandora Bio, Inc. | ROBINSON, KYLE G | 3685 | §101§103 | Non-Final OA | — | Pending | Dec 27, 2024 |
| 18973571 | SURFACE STRUCTURE FOR FLUID MANIPULATION | Volta Labs, Inc. | FLETCHER III, WILLIAM P | 1759 | §103§112 | Non-Final OA | 26d overdue | Pending | Dec 09, 2024 |
| 18971494 | SYSTEMS AND METHODS FOR ROBOTIC BRONCHOSCOPY NAVIGATION | Noah Medical Corporation | WOO, JAE KYUN | 3795 | §102§103 | Non-Final OA | — | Pending | Dec 06, 2024 |
| 18970393 | MULTI-CATHETER SYSTEMS FOR TREATING HEART FAILURE | Pulnovo Medical Inc. | KHANDKER, RAIHAN R | 3771 | §103§112 | Non-Final OA | — | Pending | Dec 05, 2024 |
| 18951439 | SECURE ELECTRIC VEHICLE CHARGER AND SYSTEM INCORPORATING THEREOF | Eve Energy Ventures Inc. | WRIGHT, BRYAN F | 2497 | §103 | Non-Final OA | — | Pending | Nov 18, 2024 |
| 18951298 | METHODS AND APPARATUS FOR EVALUATING DEVELOPMENTAL CONDITIONS AND PROVIDING CONTROL OVER COVERAGE AND RELIABILITY | Cognoa, Inc. | WILLIAMS, TERESA S | §101§102§103 | Non-Final OA | — | Pending | Nov 18, 2024 | |
| 18941418 | DEVICES FOR BIOLOGICAL ANALYSIS | Cellsbin, Inc. | UNDERWOOD, JARREAS C | 2877 | §103 | Final Rejection | — | Pending | Nov 08, 2024 |
| 18935201 | METHODS AND DEVICES FOR MEMBRANE CHARACTERIZATION WITH ULTRASOUND AND OPTICAL ILLUMINATION | Otonexus Medical Technologies, Inc. | IP, JASON M | 3797 | §103 | Final Rejection | 46d | Pending | Nov 01, 2024 |
| 18931558 | CHOLIX TOXIN-DERIVED FUSION MOLECULES FOR ORAL DELIVERY OF BIOLOGICALLY ACTIVE CARGO | Thornhill Therapeutics, Inc. | ZEMAN, ROBERT A | §102§103Other | Non-Final OA | — | Pending | Oct 30, 2024 | |
| 18928814 | BETA-LACTAM DERIVATIVES FOR THE TREATMENT OF DISEASES | Insilico Medicine Ip Limited | DAVIS, BRIAN J | DP | Non-Final OA | — | Pending | Oct 28, 2024 | |
| 18924896 | COMPLEX IMAGE DATA ANALYSIS USING ARTIFICIAL INTELLIGENCE AND MACHINE LEARNING ALGORITHMS | Sirona Medical, Inc. | BAKER, CHARLOTTE M | §102 | Non-Final OA | — | Pending | Oct 23, 2024 | |
| 18903693 | SYSTEMS AND METHODS FOR ANOMALY DETECTION USING EXPLAINABLE MACHINE LEARNING ALGORITHMS | Hawk AI GmbH | MAGUIRE, LINDSAY M | 3619 | §101 | Final Rejection | 9d | Pending | Oct 01, 2024 |
| 18894460 | APPARATUS FOR MANIPULATION OF EAR DEVICES | Earplace Inc. | SHAH, JAY B | §102§103§112 | Non-Final OA | — | Pending | Sep 24, 2024 | |
| 18891790 | PHENOTYPE MEASUREMENT SYSTEMS AND METHODS | Fenologica Biosciences, Inc. | GILLIARD, DELOMIA L | §103DP | Non-Final OA | — | Pending | Sep 20, 2024 | |
| 18890248 | INHIBITORS OF MEK KINASE | Mosaica Medicines, Inc. | STOCKTON, LAURA LYNNE | DP | Non-Final OA | — | Pending | Sep 19, 2024 | |
| 18890562 | INTEGRATED PLATFORM FOR DIGITAL ASSET REGISTRATION, TRACKING AND VALIDATION | Figure Lending Corporation | SHARON, AYAL I | 3695 | §101§103 | Final Rejection | — | Pending | Sep 19, 2024 |
| 18883711 | ARTIFICIAL INTELLIGENCE PHYSICS-BASED MODELING OF CARDIAC PARAMETERS | Delbeat, Inc. | HAKALA, ALAN GREGORY | 2617 | §102§103 | Non-Final OA | 14d | Pending | Sep 12, 2024 |
| 18821111 | SYSTEM FOR DIAGNOSING, TRACKING, AND PREDICTING RECOVERY PATTERNS IN PATIENTS WITH TRAUMATIC BRAIN INJURY | Mayo Foundation for Medical Education and Research | BODENDORF, ANDREW | 3715 | §101§102§103 | Non-Final OA | — | Pending | Aug 30, 2024 |
| 18841639 | DIACYLGLYCEROL KINASE (DGK) ALPHA INHIBITORS AND USES THEREOF | Insilico Medicine Ip Limited | SHTERENGARTS, SAMANTHA L | §102DP | Non-Final OA | — | Pending | Aug 26, 2024 | |
| 18813959 | COMPOSITIONS AND METHODS FOR IMPROVING COGNITIVE FUNCTION | Diamond Therapeutics Inc. | COPPINS, JANET L | 1628 | §103 | Final Rejection | — | Pending | Aug 23, 2024 |
| 18814218 | EFFICIENT STORAGE AND RETRIEVAL OF SMALL OBJECTS | Tigris Data, Inc. | UDDIN, MD I | 2169 | §103 | Non-Final OA | — | Pending | Aug 23, 2024 |
| 18806109 | Unsupervised Machine Learning Methods | Ampel Biosolutions, LLC | DAUNER, JOSEPH G | 1682 | §102§103§112 | Final Rejection | 28d | Pending | Aug 15, 2024 |
| 18837847 | MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE (PKMYT1) INHIBITORS AND USES THEREOF | Insilico Medicine Ip Limited | WHITE, DAWANNA SHAR-DAY | §103DP | Non-Final OA | — | Pending | Aug 12, 2024 | |
| 18837846 | MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE (PKMYT1) INHIBITORS AND USES THEREOF | Insilico Medicine Ip Limited | ROBINSON, MIKHAIL O'DONNEL | §103 | Non-Final OA | — | Pending | Aug 12, 2024 | |
| 18800872 | INTEGRATED FINANCIAL SERVICES PLATFORMS AND METHODS OF USE | Figure Technologies, Inc. | EKECHUKWU, CHINEDU U | 3695 | §103 | Non-Final OA | 12d | Pending | Aug 12, 2024 |
| 18797817 | BIOCERAMIC COMPOSITIONS AND BIOMODULATORY USES THEREOF | Multiple Energy Technologies LLC | PAK, JOHN D | §103§112 | Non-Final OA | — | Pending | Aug 08, 2024 | |
| 18794589 | CRYSTAL FORMS OF A POL1 INHIBITOR | Pimera, Inc. | KUCHARCZK, JED A | DP | Non-Final OA | — | Pending | Aug 05, 2024 | |
| 18835167 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Mrja Therapeutics, Inc. | PECKHAM, RICHARD GRANT | §112 | Non-Final OA | — | Pending | Aug 01, 2024 | |
| 18785556 | METHODS AND COMPOSITIONS FOR TREATING POLYCYSTIC OVARY SYNDROME | Spruce Biosciences, Inc. | RAHMANI, NILOOFAR | §112DP | Non-Final OA | — | Pending | Jul 26, 2024 | |
| 18784718 | OPHTHALMIC COMPOSITION | Sydnexis, Inc. | LEE, WILLIAM Y | 1623 | §103Other | Non-Final OA | 10d overdue | Pending | Jul 25, 2024 |
| 18776022 | SYSTEMS AND METHODS FOR PROMOTING CORAL GROWTH, HEALTH, OR RESILIENCY | Coral Vita Inc. | BITOR, RENAE ALLYN | 2663 | §102§103§112 | Non-Final OA | — | Pending | Jul 17, 2024 |
| 18767896 | APPARATUS AND METHOD FOR SPEECH PROCESSING USING A DENSELY CONNECTED HYBRID NEURAL NETWORK | Reflex Technologies, Inc. | ARMSTRONG, ANGELA A | 2659 | §103 | Non-Final OA | 126d overdue | Pending | Jul 09, 2024 |
| 18765066 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PRESBYOPIA | Lenz Therapeutics Operations, Inc. | DIAMOND, ALAN D | 3991 | §112 | Non-Final OA | 5d overdue | Pending | Jul 05, 2024 |
| 18765156 | CONTACT LENS COMPOSITIONS AND METHODS FOR THE TREATMENT OF PRESBYOPIA | Lenz Therapeutics Operations, Inc. | DIAMOND, ALAN D | 3991 | §103Other | Non-Final OA | 5d overdue | Pending | Jul 05, 2024 |
| 18763381 | OPHTHALMIC COMPOSITION AND DELIVERY DEVICE THEREOF | Sydnexis, Inc. | KALIHER, HANS CHRISTIAN | 3781 | §103§112 | Final Rejection | — | Pending | Jul 03, 2024 |
| 18762386 | RELAXATION-BASED MAGNETIC RESONANCE THERMOMETRY WITH A LOW-FIELD SINGLE-SIDED MRI SCANNER | Promaxo, Inc. | JASANI, ASHISH SHIRISH | 3798 | §103 | Non-Final OA | 63d | Pending | Jul 02, 2024 |
| 18725070 | PREPARATION OF A COMPOUND FOR THE TREATMENT OF GOUT OR HYPERURICEMIA | Arthrosi Therapeutics, Inc. | HERNANDEZ, JACKSON J | §102§103§112 | Non-Final OA | — | Pending | Jun 27, 2024 | |
| 18753922 | Secure Electric Vehicle Charger and System Incorporating Thereof | Eve Energy Ventures Inc. | WRIGHT, BRYAN F | 2497 | §103§112 | Final Rejection | 52d overdue | Pending | Jun 25, 2024 |
| 18752362 | Unsupervised Machine Learning Methods | Ampel Biosolutions, LLC | CLOW, LORI A | 1687 | §101§102§112 | Non-Final OA | — | Pending | Jun 24, 2024 |
| 18722528 | METHODS AND COMPOSITIONS FOR IMPROVED MOLECULAR THERAPIES OF MULTIGENIC DISEASES | Land Medicine Inc. | CANDELARIA, JULIANA IRENE | §103§112 | Non-Final OA | — | Pending | Jun 20, 2024 | |
| 18743649 | SINGLE-MOLECULE PEPTIDE SEQUENCING THROUGH MOLECULAR BARCODING AND EX-SITU ANALYSIS | Glyphic Biotechnologies, Inc. | PRIEST, AARON A | §103§112 | Non-Final OA | — | Pending | Jun 14, 2024 | |
| 18738282 | SYSTEMS AND METHODS FOR POSE ESTIMATION OF IMAGING SYSTEM | Noah Medical Corporation | SHENG, CHAO | 3797 | §103§112 | Final Rejection | — | Pending | Jun 10, 2024 |
| 18738838 | EPITOPE FOCUSING BY VARIABLE EFFECTIVE ANTIGEN SURFACE CONCENTRATION | Centivax, Inc. | CHESTNUT, BARRY A | DP | Non-Final OA | — | Pending | Jun 10, 2024 | |
| 18732126 | SYSTEMS AND METHODS FOR ANALYZING A TARGET MOLECULE | Axbio Inc. | GIAMMONA, FRANCESCA FILIPPA | 1681 | §103 | Final Rejection | — | Pending | Jun 03, 2024 |
| 18678320 | SYSTEM AND METHOD FOR CORRECTING PATIENT INDEX | Cytovale Inc. | KWAK, DEAN P | 1798 | §102§103§112 | Non-Final OA | 2d overdue | Pending | May 30, 2024 |
| 18714015 | CRYSTALLINE FORMS OF A COMPOUND FOR TREATING OR PREVENTING GOUT OR HYPERURICEMIA | Arthrosi Therapeutics, Inc. | GONZALEZ, LUISALBERTO | §102§112 | Non-Final OA | — | Pending | May 28, 2024 | |
| 18669880 | FOLDABLE DENTAL SCOPE | Get-Grin Inc. | TEITELBAUM, MICHAEL E | 2422 | §102§103 | Non-Final OA | 30d | Pending | May 21, 2024 |
| 18668242 | Aortic Heart Valve Devices | Raghuveer Basude | PRESTON, REBECCA STRASZHEIM | §103§112 | Non-Final OA | — | Pending | May 19, 2024 | |
| 18711434 | TABLET FORMULATIONS OF RBP4 INHIBITORS AND METHODS OF USE | Belite Bio, Inc. | JANOSKO, CHASITY PAIGE | 1613 | §103 | Non-Final OA | — | Pending | May 17, 2024 |
| 18666047 | SHELF-STABLE FORMULATIONS OF BENZOYL PEROXIDE AND METHODS OF PRODUCING SAME | BLUE HILL TECHNOLOGIES LLC | DONOHUE, SEAN R | 1618 | §103 | Final Rejection | 105d overdue | Pending | May 16, 2024 |
| 18662754 | METHODS AND SYSTEMS FOR AUDIO SAMPLE QUALITY CONTROL | Clearspeed Inc. | SHAH, ANTIM G | 2693 | §103 | Non-Final OA | 38d overdue | Pending | May 13, 2024 |
| 18708947 | THIOPHENE ULK1/2 INHIBITORS AND THEIR USE THEREOF | Erasca, Inc. | ROMERO, KRISTEN WANG | §102§112 | Non-Final OA | — | Pending | May 09, 2024 | |
| 18656278 | SYSTEMS AND METHODS FOR STOOL CHARACTERIZATION AS NON-INVASIVE MEASURES OF DISEASE ACTIVITY | Cylinder Health, Inc. | RUIZ, JOSHUA DAMIAN | 3684 | §101 | Non-Final OA | 30d overdue | Pending | May 06, 2024 |
| 18705742 | SARS-COV-2 INHIBITORS FOR TREATING CORONAVIRUS INFECTIONS | Insilico Medicine Ip Limited | HASTINGS, ALISON AZAR | 1629 | §103§112DP | Non-Final OA | — | Pending | Apr 29, 2024 |
| 18649700 | ANALYZING PHENOTYPES OF CELLS | Deepcell, Inc. | LANTZ, KARSTEN FOSTER | 2664 | §103§112 | Non-Final OA | — | Pending | Apr 29, 2024 |
| 18704366 | PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS AND USES THEREOF | Insilico Medicine Ip Limited | O DELL, DAVID K | DP | Non-Final OA | — | Pending | Apr 24, 2024 | |
| 18704395 | IFENPRODIL SALTS AND THERAPEUTIC USES THEREOF | Algernon Pharmaceuticals Inc. | LADD, CAROLYN LOUISE | 1622 | §103 | Non-Final OA | — | Pending | Apr 24, 2024 |
| 18702772 | METHIONINE ADENOSYLTRANSFERASE 2a (MAT2A) INHIBITORS AND USES THEREOF | Insilico Medicine Ip Limited | WILLIS, DOUGLAS M | §112DP | Non-Final OA | — | Pending | Apr 18, 2024 | |
| 18702652 | (S)-1-(1-ACRYLOYLPIPERIDIN-3-YL)-2-FLUORO-5,6,7,8,9,10-HEXAHYDROCYCLO HEPTA[B]INDOLE-4-CARBOXAMIDE, AND RELATED CRYSTALLINE FORMS, COMPOSITIONS, AND METHODS THEREOF | Vidya Therapeutics, Inc. | LEE, WILLIAM Y | 1623 | §102§103 | Non-Final OA | — | Pending | Apr 18, 2024 |
| 18634598 | ACTIVE LEARNING FOR WEARABLE HEALTH SENSOR | Evidation Health, Inc. | SZUMNY, JONATHON A | 3686 | §112 | Non-Final OA | 4d overdue | Pending | Apr 12, 2024 |
| 18700232 | METHOD OF TREATING ADDICTION | Anebulo Pharmaceuticals, Inc. | IVANOVA, SVETLANA M | 1627 | §102§103 | Non-Final OA | — | Pending | Apr 10, 2024 |
| 18628411 | TIDAL VOLUME, PRESSURE, INSPIRATORY TIME, AND VENTILATION RATE MEASUREMENT DEVICE DURING MANUAL VENTILATION | Safebvm Corp. | SIPPEL, RACHEL T | §103§112 | Non-Final OA | — | Pending | Apr 05, 2024 | |
| 18626751 | TREATMENT OF HYPERTENSION BY RENAL VASCULAR DELIVERY OF GUANETHIDINE | Mercator Medsystems, Inc. | GRAY, PHILLIP A | §103 | Non-Final OA | — | Pending | Apr 04, 2024 | |
| 18614506 | COMPOSITIONS, METHODS AND SYSTEMS FOR PROTEIN CORONA ANALYSIS AND USES THEREOF | Seer, Inc. | RAMADAN, OMAR | 1678 | §103 | Final Rejection | 23d overdue | Pending | Mar 22, 2024 |
| 18694836 | PYRROLE[2,3-B]PYRIDINE DERIVATIVES AS TYRO3 INHIBITORS | Halia Therapeutics, Inc. | OTTON, ALICIA L | 1699 | §112 | Final Rejection | — | Pending | Mar 22, 2024 |
| 18612795 | SYSTEMS AND METHODS FOR SAMPLE COLLECTION | Drawbridge Health, Inc. | TOMBERS, JOSEPH A | 3791 | §102§103§112 | Non-Final OA | 7d | Pending | Mar 21, 2024 |
| 18612081 | METHODS AND SYSTEMS FOR DETERMINING SOURCES OF ANOMALIES IN MANUFACTURING PROCESSES | Gauss Labs Inc. | PATEL, JIGNESHKUMAR C | 2116 | §101§102§103 | Non-Final OA | — | Pending | Mar 21, 2024 |
| 18607804 | ULTRA-HIGH RESOLUTION CT RECONSTRUCTION USING GRADIENT GUIDANCE | Subtle Medical, Inc. | ALFONSO, DENISE G | 2662 | §103 | Non-Final OA | 26d overdue | Pending | Mar 18, 2024 |
| 18607814 | SYSTEMS AND METHODS FOR CONTRAST DOSE REDUCTION | Subtle Medical, Inc. | ALFONSO, DENISE G | 2662 | §102§103 | Non-Final OA | 26d overdue | Pending | Mar 18, 2024 |
| 18605099 | COMPOSITIONS AND FORMULATIONS FOR TOPICAL USE OF AN AKT INHIBITOR FOR THE PREVENTION, TREATMENT, AND IMPROVEMENT OF SKIN DISEASES, CONDITIONS, AND DISORDERS | Dermbiont, Inc. | DROUIN, STEVE HOANG | 1627 | §102§103 | Non-Final OA | — | Pending | Mar 14, 2024 |
| 18691648 | METHOD FOR PREPARING STRUCTURALLY COLOURED FILMS AND PIGMENTS | Sparxell UK Limited | WIECZOREK, MICHAEL P | §102§103§112 | Non-Final OA | — | Pending | Mar 13, 2024 | |
| 18603041 | SYSTEMS AND METHODS FOR COMBINING DATA ANALYSES | Datawalk Spólka Akcyjna | OBISESAN, AUGUSTINE KUNLE | 2156 | §103 | Final Rejection | 12d | Pending | Mar 12, 2024 |
| 18602468 | SYSTEMS AND METHODS FOR NOISE-AWARE SELF-SUPERVISED ENHANCEMENT OF IMAGES USING DEEP LEARNING | Subtle Medical, Inc. | FUJITA, KATRINA R | 2672 | §103 | Non-Final OA | 3d overdue | Pending | Mar 12, 2024 |
| 18603124 | POLYNUCLEOTIDE CONSTRUCTS | Sirius Therapeutics, Inc. | BRETZ, COREY LANE | 1600 | §103DP | Non-Final OA | — | Pending | Mar 12, 2024 |
| 18599002 | STROMAL STEM CELLS | Orbsen Therapeutics Limited | KNIGHT, TERESA E | DP | Non-Final OA | — | Pending | Mar 07, 2024 | |
| 18594287 | SYSTEMS AND METHODS FOR SELF-ALIGNMENT AND ADJUSTMENT OF ROBOTIC ENDOSCOPE | Noah Medical Corporation | JOS, BASIL T | 3658 | §103 | Non-Final OA | 4d overdue | Pending | Mar 04, 2024 |
| 18594625 | A SYSTEM AND METHOD OF MERGING A CO-OPERATIVE MR-COMPATIBLE ROBOT AND A LOW-FIELD PORTABLE MRI SYSTEM | Neuro42 Inc. | ALDARRAJI, ZAINAB MOHAMMED | 3797 | §103 | Final Rejection | 23d | Pending | Mar 04, 2024 |
| 18590521 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | MEAH, MOHAMMAD Y | 1652 | §112 | Non-Final OA | — | Pending | Feb 28, 2024 |
| 18589357 | MONITORING OF HEALTH CONDITIONS USING A REAL-TIME AND CONTINUOUS BLOOD PRESSURE MEASURING SYSTEM | Esperto Medical, Inc. | HEALY, NOAH MICHAEL | 3791 | §102§103§112 | Non-Final OA | 18d overdue | Pending | Feb 27, 2024 |
| 18685798 | QUINAZOLINE COMPOUNDS FOR TREATMENT OF DISEASE | Arthrosi Therapeutics, Inc. | ENGLISH, CONNOR KENNEDY | 1625 | §103 | Non-Final OA | — | Pending | Feb 22, 2024 |
| 18441446 | SMALL MOLECULE MODULATORS OF FERROPTOSIS | Arpeggio Biosciences, Inc. | SHIAO, REI TSANG | 1691 | §112 | Non-Final OA | — | Pending | Feb 14, 2024 |
| 18438060 | METHODS OF TREATING CONGENITAL ADRENAL HYPERPLASIA | Spruce Biosciences, Inc. | LEE, WILLIAM Y | 1623 | §103§112DP | Final Rejection | — | Pending | Feb 09, 2024 |
| 18681811 | METHOD FOR DETECTING MEDICAL CONDITIONS USING ANALYSIS OF VERY SMALL EMBRYONIC-LIKE STEM CELLS | 23Ikigai Pte. Ltd. | CHUNDURU, SURYAPRABHA | 1681 | §101§102§103Other | Non-Final OA | — | Pending | Feb 06, 2024 |
| 18681207 | GROWTH HORMONE-RELEASING HORMONE PEPTIDES AND FORMULATIONS THEREOF | Rebalance Health, Inc. | VARADARAJ, ARCHANA | §103 | Non-Final OA | — | Pending | Feb 05, 2024 | |
| 18681163 | ANTI-CORTICOTROPIN-RELEASING HORMONE ANTIBODIES AND USE IN CONGENITAL ADRENAL HYPERPLASIA | Hbm Alpha Therapeutics, Inc. | VAN DRUFF, SYDNEY | §112 | Non-Final OA | — | Pending | Feb 05, 2024 | |
| 18681021 | METHODS AND SYSTEMS FOR PRODUCING COMPOSITE MATERIALS | Applied Bioplastics Corp. | WOODWARD, ANA LUCRECIA | §102§103§112 | Non-Final OA | — | Pending | Feb 02, 2024 | |
| 18431347 | SYSTEMS AND METHODS FOR INDUCING MUSCLE CONTRACTION | Asayena, Inc. | KUO, JONATHAN T | 3792 | §103 | Final Rejection | 60d overdue | Pending | Feb 02, 2024 |
| 18428899 | BED FRAME SUPPORT STRUCTURE, BED FRAME AND BED | Zinus Inc. | LABARGE, ALISON N | 3673 | §102§103§112 | Non-Final OA | 22d overdue | Pending | Jan 31, 2024 |
| 18425997 | SDC-2 EXOSOME COMPOSITIONS AND METHODS OF ISOLATION AND USE | Orbsen Therapeutics Limited | SPENCE, JENNIFER SUZANNE | 1633 | §101§103Other | Non-Final OA | 7d | Pending | Jan 29, 2024 |
| 18292856 | PYRROLO[2,3-b]PYRIDINE PGDH INHIBITORS AND METHODS OF MAKING AND USING | Epirium Bio Inc. | LEE, WILLIAM Y | 1623 | §112 | Non-Final OA | — | Pending | Jan 26, 2024 |
| 18424564 | METHODS AND SYSTEMS FOR PHASE GATES IN QUANTUM COMPUTERS | Universal Quantum Ltd | STOFFA, WYATT A | 2881 | §112 | Non-Final OA | 19d overdue | Pending | Jan 26, 2024 |
| 18424237 | METHOD AND SYSTEM FOR PRESENTING DENTAL SCAN | Get-Grin Inc. | BHATNAGAR, ANAND P | 2668 | §102§112 | Non-Final OA | 19d overdue | Pending | Jan 26, 2024 |
| 18424169 | MODELING DENTAL STRUCTURES FROM DENTAL SCAN | Get-Grin Inc. | ROSARIO, DENNIS | 2676 | §102§103 | Non-Final OA | — | Pending | Jan 26, 2024 |
| 18292890 | BICYCLIC PGDH INHIBITORS AND METHODS OF MAKING AND USING | Epirium Bio Inc. | CHENG, KAREN | 1623 | DP | Non-Final OA | — | Pending | Jan 26, 2024 |
| 18422976 | SALIVA PAIRED IMAGING TEST APPARATUS AND METHOD | Oral Genome Corp. | COLENA, TRACY CHING-TIAN | §103 | Non-Final OA | — | Pending | Jan 25, 2024 | |
| 18420123 | READING METHOD OF A LATERAL FLOW TEST | P4Q Health, S.L. | COLE, HOUSTON DAVID | §101§103 | Non-Final OA | — | Pending | Jan 23, 2024 | |
| 18419926 | METHODS OF ADMINISTERING MONOMETHYL FUMARATE AND PRODRUGS THEREOF HAVING REDUCED SIDE EFFECTS | Arbor Pharmaceuticals, LLC | TOWNSLEY, SARA ELIZABETH | 1629 | §103§112 | Non-Final OA | — | Pending | Jan 23, 2024 |
| 18409116 | SYSTEMS AND METHODS FOR GENETICS-BASED ANALYTICS OF HEALTH, FITNESS AND SPORTS PERFORMANCE | Cipher Genetics, Inc. | HRANEK, KAREN AMANDA | 3684 | §101§103§112 | Final Rejection | 5d | Pending | Jan 10, 2024 |
| 18405952 | RECYCLING OF BATTERIES WITH A VACUUM CRUSHING-VAPORIZATION-COLLECTION SYSTEM | Evolve Renewable Materials, Inc. | VAN OUDENAREN, MATTHEW W | §103§112 | Non-Final OA | — | Pending | Jan 05, 2024 | |
| 18405378 | SYSTEMS AND METHODS FOR COOLING | Ferveret Inc. | CAI, CHARLES J | 2115 | §102§103§112 | Non-Final OA | — | Pending | Jan 05, 2024 |
| 18574148 | REDUCTION OF ENDOTOXINS IN BACTERIAL PROTEIN PREPARATIONS | Kiverdi, Inc. | MORENO, LARK JULIA | 1793 | §102§103 | Non-Final OA | — | Pending | Dec 26, 2023 |
| 18394833 | ARTIFICIAL NANOPORES AND USES AND METHODS RELATING THERETO | Rijksuniversiteit Groningen | GERIDO, DWAN A | 1797 | §103§112 | Final Rejection | 14d | Pending | Dec 22, 2023 |
| 18395124 | PARTICLE-BASED BIOSEPARATION ASSAYS | Seer, Inc. | COLENA, TRACY CHING-TIAN | §102§103 | Non-Final OA | — | Pending | Dec 22, 2023 | |
| 18393292 | METHODS AND SYSTEMS FOR SOLVING AN INTEGER PROGRAMMING PROBLEM OR A MIXED-INTEGER PROGRAMMING PROBLEM USING A CIRCUIT-BASED CONTINUOUS-VARIABLE QUANTUM OPTICAL DEVICE | 1QB Information Technologies Inc. | KWON, JUN | §101§103 | Non-Final OA | — | Pending | Dec 21, 2023 | |
| 18573298 | COMPOSITIONS OF BETA-HEXOSAMINIDASE VARIANTS AND USES THEREOF | BIOMARIN PHARMACEUTICAL INC. | SWIFT, CANDICE LEE | 1657 | §103§112 | Non-Final OA | 4d overdue | Pending | Dec 21, 2023 |
| 18392546 | SYSTEMS AND METHODS FOR PREPARING IMAGING AND ANALYZING CYTOLOGIC SAMPLES | Invenio Imaging, Inc. | YENTRAPATI, AVINASH | 2672 | §103 | Final Rejection | — | Pending | Dec 21, 2023 |
| 18572412 | SHP2 AND CDK4/6 INHIBITORS COMBINATION THERAPIES FOR THE TREATMENT OF CANCER | Erasca, Inc. | KUCKLA, ANNA GRACE | 1626 | §103Other | Non-Final OA | 19d overdue | Pending | Dec 20, 2023 |
| 18390285 | COMPUTER-IMPLEMENTED METHOD FOR IMPROVING QUERY EXECUTION IN RELATIONAL DATABASES NORMALIZED AT LEVEL 4 AND ABOVE | Datawalk Spólka Akcyjna | MARI VALCARCEL, FERNANDO MARIANO | 2159 | §103 | Final Rejection | 74d overdue | Pending | Dec 20, 2023 |
| 18572399 | ERK1/2 AND KRAS G12C INHIBITORS COMBINATION THERAPY | Erasca, Inc. | ANDERSON, REBECCA L | 1626 | §103§112Other | Non-Final OA | 4d overdue | Pending | Dec 20, 2023 |
| 18572148 | System and Method for Determining a Stool Condition | Dieta Inc. | MAHROUKA, WASSIM | 2665 | §101§103 | Final Rejection | 66d overdue | Pending | Dec 19, 2023 |
| 18538944 | SEQUENTIAL ADAPTOR FOR COMBINED ULTRASOUND AND OPTOACOUSTIC DIAGNOSTIC INTERROGATION OF THE LEFT INNOMINATE VEIN | Noninvasix, Inc. | MORONESO, JONATHAN DREW | 3791 | §103§112 | Non-Final OA | 19d | Pending | Dec 13, 2023 |
| 18534106 | METHODS FOR DETECTING MODIFIED NUCLEOTIDES | Cambridge Enterprise Limited | KIM, YOUNG J | 1681 | §102§103§112 | Non-Final OA | — | Pending | Dec 08, 2023 |
| 18529530 | PLATFORMS FOR CONDUCTING VIRTUAL TRIALS | Cancer Commons | KANAAN, LIZA TONY | 3683 | §101§103 | Non-Final OA | 28d | Pending | Dec 05, 2023 |
| 18520811 | Portable Devices and Methods for Analyzing Samples | Biomeme, Inc. | MCGUIRK, JOHN SCHUYLER | 1798 | §103§112 | Final Rejection | 4d overdue | Pending | Nov 28, 2023 |
| 18563292 | PENICILLIN-BINDING PROTEIN INHIBITORS | Venatorx Pharmaceuticals, Inc. | WARD, PAUL V | 1622 | §112 | Non-Final OA | — | Pending | Nov 21, 2023 |
| 18562768 | BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION | BELITE BIO, LLC | RAHMANI, NILOOFAR | 1691 | §102§112 | Non-Final OA | 30d overdue | Pending | Nov 20, 2023 |
| 18511328 | SYSTEMS AND METHODS FOR REAL-TIME SYSTEMATIC HEALTH CARE | Tad Health Inc. | EGLOFF, PETER RICHARD | 3715 | §101 | Non-Final OA | 34d | Pending | Nov 16, 2023 |
| 18508585 | SCALABLE NEUTRAL ATOM BASED QUANTUM COMPUTING | Atom Computing Inc. | SMITH, DAVID E | 2881 | §102§103§112 | Non-Final OA | 12d | Pending | Nov 14, 2023 |
| 18507807 | METHODS AND SYSTEMS FOR NUCLEIC ACID ISOLATION | Seek Labs, Inc. | BORTOLI, JONATHAN | 1797 | §102§103§112 | Non-Final OA | — | Pending | Nov 13, 2023 |
| 18506287 | N6-ADENOSINE-METHYLTRANSFERASE INHIBITORS IN CANCER TREATMENT | UNIVERSITY OF ZURICH | SHIAO, REI TSANG | 1691 | §102§103 | Non-Final OA | — | Pending | Nov 10, 2023 |
| 18502595 | PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Siolta Therapeutics, Inc. | ARIANI, KADE | 1651 | — | Non-Final OA | — | Pending | Nov 06, 2023 |
| 18501238 | 5-HT2A AND/OR 5-HT2C RECEPTOR AGONISTS | Diamond Therapeutics Inc. | HABTE, KAHSAY | 1624 | §102§112 | Non-Final OA | — | Pending | Nov 03, 2023 |
| 18386765 | METHODS AND SYSTEMS FOR SHAPING MAGNETICS FIELDS TO ALIGN FORCES ON MAGNETIC PARTICLES FOR PATIENT ANATOMY AND MOTION | Otomagnetics, Inc. | DECASTRO, ARIANA JOY LACAY | §101§103§112 | Non-Final OA | — | Pending | Nov 03, 2023 | |
| 18501724 | METHODS AND COMPOSITIONS USING AN ENGINEERED RELEASE FACTOR | Opentrons Labworks Inc. | MULDER, SCOTT EVAN | 1656 | §102§103§112 | Non-Final OA | 26d | Pending | Nov 03, 2023 |
| 18500846 | SYSTEMS AND METHODS FOR AN AUTONOMOUS RIPPER | Aim Intelligent Machines, Inc. | JONES, JODI MARIE | 3666 | §103 | Final Rejection | — | Pending | Nov 02, 2023 |
| 18497531 | CRYSTALLINE CARBAZOLE DERIVATIVE | Raziel Therapeutics Ltd. | NOLAN, JASON MICHAEL | 1623 | §103§112 | Non-Final OA | — | Pending | Oct 30, 2023 |
| 18556300 | NEK7 INHIBITORS | Halia Therapeutics, Inc. | GONZALEZ, LUISALBERTO | 1624 | §112 | Final Rejection | — | Pending | Oct 19, 2023 |
| 18486374 | DIACYLGLYCEROL KINASE (DGK) ALPHA INHIBITORS AND USES THEREOF | Insilico Medicine Ip Limited | MOORE, SUSANNA | 1624 | §112DPOther | Final Rejection | — | Pending | Oct 13, 2023 |
| 18555450 | NANOSCALE REACTION CHAMBERS AND METHODS OF USING THE SAME | Partillion Bioscience Corporation | GORDON, BRIAN R | 1798 | §101§112 | Non-Final OA | — | Pending | Oct 13, 2023 |
| 18379142 | METHODS FOR THE TREATMENT OF DIABETIC RETINOPATHY AND OTHER OPHTHALMIC DISEASES | Acucela Inc. | JAVANMARD, SAHAR | 1622 | §103Other | Non-Final OA | 56d | Pending | Oct 11, 2023 |
| 18483933 | AEROSOL SAMPLE COLLECTION DEVICE | Proveris Scientific Corporation | BALAJI, KAVYA SHOBANA | 3791 | §101§102§103§112 | Non-Final OA | 79d overdue | Pending | Oct 10, 2023 |
| 18554283 | TREATMENT OF CANCER WITH KDM4 INHIBITORS | Tachyon Therapeutics, Inc. | RZECZYCKI, PHILLIP MATTHEW | 1624 | §102§103§112DP | Non-Final OA | — | Pending | Oct 06, 2023 |
| 18482789 | Functionalized Surfaces for Conversion of Carbon Dioxide | Prometheus Fuels, Inc. | WONG, EDNA | 1795 | §103§112 | Non-Final OA | — | Pending | Oct 06, 2023 |
| 18285812 | GPR119 AGONISTS | Kallyope, Inc. | REILLY, SOPHIA JANE | 1627 | §112 | Non-Final OA | 30d | Pending | Oct 05, 2023 |
| 18554174 | METHODS AND SYSTEMS FOR ANALYZING COMPLEX GENOMIC REGIONS | Rprd Diagnostics, LLC | CASH, KAILEY ELIZABETH | 1683 | §103§112DP | Non-Final OA | 82d | Pending | Oct 05, 2023 |
| 18481129 | ANTI-VENOM ANTIBODIES AND USES THEREOF | Centivax, Inc. | DONOGHUE, BRITTNEY ERIN | 1675 | §101§102§112 | Non-Final OA | — | Pending | Oct 04, 2023 |
| 18479335 | INTRANASAL DHE FOR THE TREATMENT OF HEADACHE | Satsuma Pharmaceuticals, Inc. | HAGHIGHATIAN, MINA | 1616 | DP | Non-Final OA | — | Pending | Oct 02, 2023 |
| 17998252 | METHODS FOR IDENTIFYING A MEDICAL CONDITION IN A HUMAN SUBJECT | 23 Ikigai Pte. Ltd. | GIAMMONA, FRANCESCA FILIPPA | 1681 | §101§112Other | Non-Final OA | — | Pending | Sep 29, 2023 |
| 18476928 | SYSTEMS AND METHODS FOR ARTIFICIAL INTELLIGENCE-ASSISTED IMAGE ANALYSIS | Sirona Medical, Inc. | BARTLEY, KENNETH | 3684 | §101§103 | Final Rejection | 18d overdue | Pending | Sep 28, 2023 |
| 18476263 | SYSTEMS AND METHODS FOR OPTICAL ILLUMINATION IN A SPECULUM TIP | Otonexus Medical Technologies, Inc. | TAYLOR, APRIL ALICIA | 2876 | §102§103 | Non-Final OA | — | Pending | Sep 27, 2023 |
| 18473089 | THREE-DIMENSIONAL ORTHOSES HAVING MULTIPLE ADJUSTMENT FEATURES AND METHODS FOR THEIR MANUFACTURE AND USE | Osteoid Saglik Teknolojileri A.S. | NELSON, KERI JESSICA | 3786 | §103 | Non-Final OA | — | Pending | Sep 22, 2023 |
| 18369788 | SYSTEMS AND METHODS FOR ENGINEERING PROTEIN ACTIVITY | Aether Biomachines, Inc. | MINCHELLA, KAITLYN L | 1685 | §101§103§112 | Final Rejection | 19d | Pending | Sep 18, 2023 |
| 18467037 | TRANS-SPLICING METHODS AND COMPOSITIONS FOR GENERATION OF SINGLE SEX OFFSPRING | Jfl Capital Management, LLC | NGUYEN, QUANG | 1631 | §112Other | Non-Final OA | 18d overdue | Pending | Sep 14, 2023 |
| 18550428 | BIOCERAMIC COMPOSITIONS FOR CANCER RECOVERY | Multiple Energy Technologies LLC | COLLINS, SEAN W | 3794 | §103§112 | Non-Final OA | 2d overdue | Pending | Sep 13, 2023 |
| 18461368 | ENGINEERED IMMUNE CELL THERAPIES | Factor Bioscience Inc. | VANHORN, ABIGAIL LOUISE | 1636 | §103§112DP | Final Rejection | 9d overdue | Pending | Sep 05, 2023 |
| 18241733 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PRESBYOPIA | Lenz Therapeutics Operations, Inc. | WRIGHT, SARAH C | 1619 | Other | Final Rejection | 15d overdue | Pending | Sep 01, 2023 |
| 18548538 | DIRECTED LASER ENERGY TO REDUCE METAL OXIDES | Limelight Steel Inc. | SMOOT, MORIAH SIMONE MCMIL | 1733 | §103§112 | Non-Final OA | 21d | Pending | Aug 31, 2023 |
| 18458397 | SITE SPECIFIC ANTIBODY-DRUG CONJUGATES WITH PEPTIDE-CONTAINING LINKERS | Mersana Therapeutics, Inc. | PUTTLITZ, KARL J | 1642 | §102DPOther | Non-Final OA | — | Pending | Aug 30, 2023 |
| 18453798 | COMPOUNDS AND METHODS FOR MODULATING HER2 | Iambic Therapeutics, Inc. | PATEL, SAGAR S | 1626 | DP | Final Rejection | 17d overdue | Pending | Aug 22, 2023 |
| 18547190 | ANALOGS FOR THE TREATMENT OF DISEASE | Insilico Medicine Ip Limited | LADD, CAROLYN LOUISE | 1622 | §102 | Non-Final OA | — | Pending | Aug 21, 2023 |
| 17914004 | RESPIRATOR FACE MASKS FOR PROTECTION FROM AIRBORNE PARTICLES | Encellin, Inc. | EZELUOMBA, MIRIAM NCHEKWUBECHU | 1776 | §102§103§112 | Non-Final OA | 16d overdue | Pending | Aug 18, 2023 |
| 18450638 | COMBINATION OF RAF INHIBITOR AND MEK INHIBITOR | Day One Biopharmaceuticals, Inc. | HUI, SAN MING R | 1627 | §103Other | Non-Final OA | 11d overdue | Pending | Aug 16, 2023 |
| 18450775 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | SAEED, KAMAL A | 1626 | §103 | Non-Final OA | — | Pending | Aug 16, 2023 |
| 18546560 | TRPM8 AGONISTS AS COOLING AGENTS AND FOR THE TREATMENT OF DISEASE | Concentric Analgesics, Inc. | NOLAN, JASON MICHAEL | 1623 | §102 | Non-Final OA | 8d | Pending | Aug 15, 2023 |
| 17759944 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | HAVLIN, ROBERT H | 1626 | §102 | Non-Final OA | 71d | Pending | Aug 10, 2023 |
| 18276588 | ANTIBACTERIAL COMPOUNDS | Blacksmith Medicines, Inc. | JACKSON, SHAWQUIA | 1626 | — | Non-Final OA | 31d overdue | Pending | Aug 09, 2023 |
| 18446625 | SYSTEMS AND METHODS FOR HARDWARE DEVICE FINGERPRINTING | Callsign, Inc. | POUDEL, SAMIKSHYA NMN | 2436 | §103 | Final Rejection | 10d overdue | Pending | Aug 09, 2023 |
| 18362622 | RETRACTABLE NEEDLE CATHETER DELIVERY APPARATUS | Skydance Vascular, Inc. | ALLEN, ROBERT F | 3783 | §112DP | Final Rejection | 19d overdue | Pending | Jul 31, 2023 |
| 18275199 | SYSTEMS AND METHODS FOR MEASURING CELL SIGNALING PROTEIN ACTIVITY | Octant, Inc. | PAK, MICHAEL D | 1644 | §101§102§112Other | Non-Final OA | — | Pending | Jul 31, 2023 |
| 18361357 | IL-2 PROCYTOKINE ANTIBODY FUSION PROTEINS | Proviva Therapeutics (Hong Kong) Limited | TAYLOR, LIA ELAN | 1641 | §103§112DP | Non-Final OA | — | Pending | Jul 28, 2023 |
| 18227071 | PUMP-CONNECTABLE ANALYTE SENSING CANNULA | Pacific Diabetes Technologies Inc. | NICHOLS, CHARLES W | 3783 | §103 | Non-Final OA | — | Pending | Jul 27, 2023 |
| 18262787 | NEK7 INHIBITORS | Halia Therapeutics, Inc. | VAJDA, KRISTIN ANN | 1622 | §112 | Non-Final OA | — | Pending | Jul 25, 2023 |
| 18358762 | METHODS AND SYSTEMS FOR AUTOMATED PNEUMATIC OTOSCOPY | Otonexus Medical Technologies, Inc. | YOON, CHANEL J | 3791 | §103 | Non-Final OA | — | Pending | Jul 25, 2023 |
| 18358886 | USE OF AN EMULSIFIER DERIVED FROM RICINOLEIC ACID TO INCREASE THE ABSORPTION OF CALCIUM AND PHOSPHORUS IN THE DIGESTIVE TRACT OF FARM ANIMALS | Gfsa Industria De Alimentação Animal Ltda | HUANG, GIGI GEORGIANA | 1613 | §102§103§112DP | Non-Final OA | — | Pending | Jul 25, 2023 |
| 18356688 | PLATELET ALPHA-GRANULES FOR DELIVERY OF MULTIPLE PROTEINS | Csts Health Care Inc. | BOWLES, DAVID PAUL | 1654 | §103§112 | Non-Final OA | 30d | Pending | Jul 21, 2023 |
| 18354506 | SYSTEMS AND METHODS FOR REAL-TIME SEARCH BASED GENERATIVE ARTIFICIAL INTELLIGENCE | SuSea, Inc. | RAMIREZ BRAVO, BEATRIZ A | 2146 | §103 | Non-Final OA | 73d overdue | Pending | Jul 18, 2023 |
| 18000099 | METHOD FOR PREPARING GLP-1 RECEPTOR AGONIST | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | YOO, SUN JAE | 1621 | §102§112 | Non-Final OA | — | Pending | Jul 17, 2023 |
| 18000108 | METHOD FOR PREPARING GLP-1 RECEPTOR AGONIST FREE BASE | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | ANDERSON, REBECCA L | 1626 | §112 | Non-Final OA | — | Pending | Jul 17, 2023 |
| 18340765 | ORAL DELIVERY OF THERAPEUTIC MAMMALIAN CELLS | Direct Biologics, LLC | MCCORMICK, CATHERINE LYNN | 1638 | Other | Non-Final OA | 54d | Pending | Jun 23, 2023 |
| 18258714 | SYSTEMS AND METHODS FOR PRESERVATION OF A CERVICOVAGINAL FLUID SAMPLE | NextGen Jane, Inc. | MCCORMACK, ERIN KATHLEEN | 3791 | §103§112 | Non-Final OA | 10d overdue | Pending | Jun 21, 2023 |
| 18336201 | SYSTEMS AND METHODS FOR IDENTIFYING AND DISTINGUISHING GENETIC SAMPLES | Revere Biosensors, LLC | CROW, ROBERT THOMAS | 1683 | DP | Final Rejection | 14d | Pending | Jun 16, 2023 |
| 18267644 | Substituted Cyclohexanecarboxamides, Their Preparation and Their Therapeutic Application | Sanofi | CHENG, KAREN | 1623 | §103 | Non-Final OA | — | Pending | Jun 15, 2023 |
| 18334975 | MEDICAL CART FOR MAGNETIC TREATMENT OF MIDDLE EAR CONDITIONS | Otomagnetics, Inc. | REDDY, SUNITA | 3791 | §112 | Non-Final OA | 5d overdue | Pending | Jun 14, 2023 |
| 18257273 | PHARMACEUTICAL FORMULATIONS OF A PHENOLIC TRPV1 AGONIST PRODRUG | Concentric Analgesics, Inc. | BARSKY, JARED | 1628 | §103DPOther | Final Rejection | — | Pending | Jun 13, 2023 |
| 18257272 | CRYSTALLINE FORM OF A PHENOLIC TRPV1 AGONIST PRODRUG | Concentric Analgesics, Inc. | RICCI, CRAIG D | 1611 | §102 | Non-Final OA | — | Pending | Jun 13, 2023 |
| 18266970 | OLIGONUCLEOTIDE ANALOGUE THERAPEUTICS FOR TREATMENT OF NEUROMUSCULAR DISEASE | Neubase Therapeutics, Inc. | HASTINGS, ALISON AZAR | 1627 | §102§103§112Other | Non-Final OA | 4d overdue | Pending | Jun 13, 2023 |
| 18266793 | KINASE INHIBITORS AND USES THEREOF | Mosaica Medicines, Inc. | ENGLISH, CONNOR KENNEDY | 1625 | §112 | Non-Final OA | — | Pending | Jun 12, 2023 |
| 18332403 | SPLIT-FRAME CARDIAC VALVES | Open Stent Solution SAS | MATHEW, SEEMA | 3774 | §102§103 | Non-Final OA | 32d overdue | Pending | Jun 09, 2023 |
| 18256276 | HALF-LIFE EXTENDING COMPOSITIONS AND METHODS | Janux Therapeutics, Inc. | SAOUD, CHRISTINE J | 1645 | DP | Final Rejection | 37d overdue | Pending | Jun 07, 2023 |
| 18328429 | SYSTEMS AND METHODS FOR PROCESSING STOOL SAMPLES | Biomesense, Inc. | NGUYEN, HENRY H | 1758 | §102§103 | Non-Final OA | 19d | Pending | Jun 02, 2023 |
| 18327740 | METHOD OF TREATING SCHIZOPHRENIA OR SCHIZOPHRENIFORM DISORDER | Curemark, LLC | BROWE, DAVID | 1617 | §103Other | Non-Final OA | 62d | Pending | Jun 01, 2023 |
| 18255227 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Neupharma, Inc. | LEE, CHIHYI NMN | 1628 | §102§112DP | Non-Final OA | — | Pending | May 31, 2023 |
| 18323674 | LASOFOXIFENE COMBINATION TREATMENT OF ER+ BREAST CANCER THAT HAS PROGRESSED ON A CDK4/6 INHIBITOR | Eli Lilly And Company | NOTTINGHAM, KYLE GREGORY | 1621 | §102§103§112 | Non-Final OA | 22d overdue | Pending | May 25, 2023 |
| 18254433 | METHODS FOR CLASSIFICATION OF LIVER DISEASE | Tensor Biosciences, Inc. | HOPPE, EMMA RUTH | 1683 | §101§102§103§112Other | Non-Final OA | 146d overdue | Pending | May 25, 2023 |
| 18038542 | MODULAR TEXTILE RECYCLING SYSTEM AND PROCESS | Ravel Holdings, Inc. | ROSEBACH, CHRISTINA H.W. | 1766 | §103§112 | Final Rejection | 49d overdue | Pending | May 24, 2023 |
| 18200121 | BIOREACTOR SYSTEMS AND METHODS FOR CULTURING CELLS | TurtleTree Labs Pte. Ltd. | BRAZIN, JACQUELINE | 1798 | §102§103 | Non-Final OA | 27d | Pending | May 22, 2023 |
| 18252611 | MAGL INHIBITORS | H. Lundbeck A/S | NOLAN, JASON MICHAEL | 1623 | Other | Final Rejection | — | Pending | May 11, 2023 |
| 18315025 | METHODS AND SYSTEMS FOR SAMPLE NORMALIZATION | Accuragen Holdings Limited | SCHLOOP, ALLISON ELIZABETH | 1682 | §101§112 | Non-Final OA | — | Pending | May 10, 2023 |
| 18314090 | TUMOR ACTIVATED MULTISPECIFIC ANTIBODIES FOR TARGETING CD28 AND PD-L1 AND METHODS OF USE THEREOF | Janux Therapeutics, Inc. | LEE, YIE CHIA | 1642 | §112Other | Non-Final OA | — | Pending | May 08, 2023 |
| 18313146 | METHODS FOR DETECTION OF NUCLEOTIDE MODIFICATION | BLUECAT IP LIMITED | GIAMMONA, FRANCESCA FILIPPA | 1681 | §103§112Other | Non-Final OA | 30d overdue | Pending | May 05, 2023 |
| 18251817 | SPECIFIC SUBSTRATES AND PRODUCTS OF HSD17B13 AS MARKERS OF LIVER DISEASE AND BIOMARKERS FOR LIVER DISEASE TREATMENT | Inipharm, Inc. | MISHRA, DEEPA | 1657 | §101§102§103§112 | Non-Final OA | 81d overdue | Pending | May 04, 2023 |
| 18308318 | METHODS AND COMPOSITIONS RELATING TO BIOMARKERS FOR NEURODEGENERATIVE DISEASES | Anacalypsis Therapeutics, Ike | BORGEEST, CHRISTINA M | 1675 | §101§102§103§112 | Non-Final OA | — | Pending | Apr 27, 2023 |
| 18033280 | SHUTTLE AGENT PEPTIDES OF MINIMAL LENGTH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS | Feldan Bio Inc. | LIPPOLIS, ALEXANDRA ROSE | 1637 | §102 | Non-Final OA | 20d | Pending | Apr 21, 2023 |
| 18305234 | PORTABLE ATMOSPHERIC WATER GENERATOR | Spout Ventures Inc. | KURTZ, BENJAMIN M | 1779 | §102§103§112 | Non-Final OA | 21d | Pending | Apr 21, 2023 |
| 18249944 | TREATMENT OF HEMATOLOGICAL MALIGNANCIES WITH INHIBITORS OF MENIN | Kura Oncology, Inc. | SHOWALTER, ALEXANDER KEITH | 1629 | §103Other | Final Rejection | — | Pending | Apr 20, 2023 |
| 18249886 | MULTISPECIFIC ANTIBODIES FOR TARGETING CD28 AND PD-L1 AND METHODS OF USE THEREOF | Janux Therapeutics, Inc. | TAYLOR, LIA ELAN | 1641 | §103§112 | Non-Final OA | 33d | Pending | Apr 20, 2023 |
| 18249879 | ANTIBODIES TARGETING HER2 AND CD3 AND USES THEREOF | Janux Therapeutics, Inc. | FAUST, AMBER KATHLEEN | 1643 | §103DPOther | Final Rejection | 61d | Pending | Apr 20, 2023 |
| 18302721 | POLYPEPTIDES | Sorriso Pharmaceuticals, Inc. | SANG, HONG | 1646 | DP | Non-Final OA | — | Pending | Apr 18, 2023 |
| 18135484 | VIRAL AND HOST BIOMARKERS FOR DETECTION, THERAPEUTIC EFFECTIVENESS, AND MONITORING OF CANCER LINKED TO SARS-CoV-2 AND HUMAN PAPILLOMA VIRUS | Lifegene-Biomarks, Inc. | PENNINGTON, HALLIE NICOLE | 1671 | §103§112 | Non-Final OA | 60d overdue | Pending | Apr 17, 2023 |
| 18032329 | PEPTIDE-BASED TRANSDUCTION OF NON-ANIONIC POLYNUCLEOTIDE ANALOGS FOR GENE EXPRESSION MODULATION | Feldan Bio Inc. | VANHORN, ABIGAIL LOUISE | 1636 | DP | Final Rejection | 7d | Pending | Apr 17, 2023 |
| 18134854 | COMPOSITIONS AND METHODS FOR THE PREVENTION OF TYPE I HYPERSENSITIVITY REACTIONS | Iggenix, Inc. | TRAN HO, LAM THUY VI | 1647 | §103 | Non-Final OA | 25d overdue | Pending | Apr 14, 2023 |
| 18249168 | INHALED FORMULATIONS OF PGDH INHIBITORS AND METHODS OF USE THEREOF | Myoforte Therapeutics, Inc. | WHITE, DAWANNA SHAR-DAY | 1627 | DP | Non-Final OA | 18d overdue | Pending | Apr 14, 2023 |
| 18297574 | METHOD AND SYSTEM FOR OPERATING A ROBOTIC DEVICE | Tombot, Inc. | LANDEEN, BROGAN RANE | 3791 | §102§103 | Final Rejection | — | Pending | Apr 07, 2023 |
| 18192593 | RNA COMPRISING SECRETOMES AND METHODS OF THEIR USE | Direct Biologics, LLC | PERSONS, JENNA L | 1637 | §102§103§112 | Non-Final OA | — | Pending | Mar 29, 2023 |
| 18192212 | SYSTEMS AND METHODS FOR TRACKING EMISSIONS | Nzero, Inc. | RUSS, COREY V | 3629 | §101§103 | Non-Final OA | 29d overdue | Pending | Mar 29, 2023 |
| 18191792 | COMPOSITIONS AND METHODS FOR DETECTING RARE SEQUENCE VARIANTS | Accuragen Holdings Limited | FLINDERS, JEREMY C | 1684 | §102§103DP | Non-Final OA | — | Pending | Mar 28, 2023 |
| 18028651 | PHARMACEUTICAL COMPOSITIONS OF AMORPHOUS SOLID DISPERSIONS AND METHODS OF PREPARATION THEREOF | Shenzhen Pharmacin Co., Ltd. | HEITMEIER, KENDALL NICOLE | 1621 | §103Other | Non-Final OA | 15d | Pending | Mar 27, 2023 |
| 18125474 | COMPOSITIONS AND METHODS FOR REDUCING GREENHOUSE GAS | Rumin8 Pty Ltd. | LEE, WILLIAM Y | 1623 | §103Other | Final Rejection | 8d | Pending | Mar 23, 2023 |
| 18188315 | COMPOSITIONS AND METHODS FOR GENETIC MODIFICATION AND TARGETING | Qihan-Egenesis Hong Kong Limited | WILSON, MICHAEL C | 1638 | §102§103§112 | Non-Final OA | 133d overdue | Pending | Mar 22, 2023 |
| 18185662 | SYSTEMS AND METHODS FOR NUCLEAR FUSION | Aquarius Energy, Inc. | GARNER, LILY CRABTREE | 3646 | §101§102§112 | Non-Final OA | 50d | Pending | Mar 17, 2023 |
| 18186146 | BIOPSY SYSTEM FOR ENHANCED TISSUE HARVESTING | Data Driven Diagnostic Sciences, Inc., Dba D3Sciences | DOUGHERTY, SEAN PATRICK | 3791 | §102§103§112 | Non-Final OA | 62d | Pending | Mar 17, 2023 |
| 18245132 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIPID-RELATED DISORDERS | Raziel Therapeutics Ltd. | CORNET, JEAN P | 1628 | §102§103 | Final Rejection | — | Pending | Mar 13, 2023 |
| 18119706 | METHODS, COMPOSITIONS, AND SYSTEMS FOR MAPPING LOCATIONS OF SINGLE MOLECULES IN MULTI-DIMENSIONAL SPACE | 13.8, Inc. | FLINDERS, JEREMY C | 1684 | §103DP | Non-Final OA | — | Pending | Mar 09, 2023 |
| 18116566 | SYSTEMS AND METHODS FOR QUERYING DATA | Mondoo, Inc. | MARI VALCARCEL, FERNANDO MARIANO | 2159 | §103 | Final Rejection | 53d | Pending | Mar 02, 2023 |
| 18024159 | STAT INIHIBITORY COMPOUNDS AND COMPOSITIONS | Centessa Pharmaceuticals (Uk) Limited | SHOWALTER, ALEXANDER KEITH | 1629 | §103§112Other | Non-Final OA | 72d overdue | Pending | Mar 01, 2023 |
| 18114410 | ORAL PHARMACEUTICAL COMPOSITION COMPRISING ZONISAMIDE AND PROCESS OF PREPARATION THEREOF | Azurity Pharmaceuticals, Inc. | HUANG, GIGI GEORGIANA | 1613 | §103 | Final Rejection | — | Pending | Feb 27, 2023 |
| 18114469 | ORAL PHARMACEUTICAL COMPOSITION COMPRISING ZONISAMIDE AND PROCESS OF PREPARATION THEREOF | Azurity Pharmaceuticals, Inc. | HUANG, GIGI GEORGIANA | 1613 | §103§112 | Final Rejection | 10d overdue | Pending | Feb 27, 2023 |
| 18043142 | COMBINATION THERAPY OF A RAF INHIBITOR AND A MEK INHIBITOR FOR THE TREATMENT OF SARCOMA | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | PURDY, KYLE A | 1611 | §102§103 | Final Rejection | 31d overdue | Pending | Feb 27, 2023 |
| 18113409 | MODIFIED IL-18 POLYPEPTIDES | Bright Peak Therapeutics AG | GURLEY, JAMI MICHELLE | 1647 | §103Other | Final Rejection | 22d | Pending | Feb 23, 2023 |
| 18113399 | ACTIVATABLE IL-18 POLYPEPTIDES | Bright Peak Therapeutics AG | CHATTIN, AMY MARIE | 1643 | §102§103 | Final Rejection | 5d overdue | Pending | Feb 23, 2023 |
| 18172928 | ANTIBODY MOLECULES THAT BIND TO NKP30 AND USES THEREOF | Marengo Therapeutics, Inc. | SUNSHINE, HANNAH LOUISE | 1647 | §112Other | Non-Final OA | 22d overdue | Pending | Feb 22, 2023 |
| 18164542 | SYSTEMS AND METHODS FOR CREATING BIOMOLECULE EMBEDDINGS | Seer, Inc. | THOMPSON, MILANA KAYE | §103§112 | Non-Final OA | — | Pending | Feb 03, 2023 | |
| 18105113 | SYSTEMS AND METHODS FOR MONITORING OF CANCER USING MINIMAL RESIDUAL DISEASE ANALYSIS | Predicine, Inc. | SCHLOOP, ALLISON ELIZABETH | 1683 | §101§103§112DP | Non-Final OA | — | Pending | Feb 02, 2023 |
| 18040310 | COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE | Fortem Neurosciences, Inc. | RICCI, CRAIG D | 1611 | §103 | Non-Final OA | — | Pending | Feb 02, 2023 |
| 18007369 | USES OF GLUCOCORTICOID RECEPTOR (GR) ANTAGONIST AND ANDROGEN RECEPTOR (AR) DEGRADER COMBINATIONS | Oric Pharmaceuticals, Inc. | ISMAIL, REHANA | 1625 | §103 | Non-Final OA | 9d overdue | Pending | Jan 30, 2023 |
| 18102268 | EXTENDED RELEASE 5-HT RECEPTOR AGONISTS FOR NEUROLOGICAL CONDITIONS | Diamond Therapeutics Inc. | SZNAIDMAN, MARCOS L | 1628 | §102§103§112 | Non-Final OA | 8d | Pending | Jan 27, 2023 |
| 18102296 | ADMINISTRATION OF MODULATORS OF 5-HT AND / OR AMPA RECEPTORS FOR TREATING NEUROLOGICAL CONDITIONS | The Royal Institution for the Advancement of Learning/McGill University | HUI, SAN MING R | 1627 | §103 | Final Rejection | 21d | Pending | Jan 27, 2023 |
| 18007032 | SYSTEMS AND METHODS FOR ASSAYING A PLURALITY OF POLYPEPTIDES | Protillion Biosciences, Inc. | BUCHANAN, BAILEY CHEYENNE | 1682 | §103§112 | Non-Final OA | — | Pending | Jan 26, 2023 |
| 18157224 | MTORC1 MODULATORS AND USES THEREOF | Aeovian Pharmaceuticals, Inc. | HIRAKIS, SOPHIA P | 1623 | §103DP | Final Rejection | 49d overdue | Pending | Jan 20, 2023 |
| 18099240 | ULTRASOUND ABLATION APPARATUS AND METHODS OF USE | Current Surgical, Inc. | ASGHAR, AMINAH | 3797 | §103 | Non-Final OA | — | Pending | Jan 19, 2023 |
| 18006142 | PARTICLES AND METHODS OF ASSAYING | Seer, Inc. | FRITCHMAN, REBECCA M | 1758 | §103§112Other | Final Rejection | — | Pending | Jan 19, 2023 |
| 18150988 | CELL PRESERVATION REAGENTS AND METHODS OF USE | Truckee Applied Genomics, LLC | ORWIG, KEVIN S | 3991 | §103Other | Non-Final OA | 189d overdue | Pending | Jan 06, 2023 |
| 18014568 | FETAL TROPHOBLAST COMPOSITIONS AND METHODS | NextGen Jane, Inc. | SCHUBERG, LAURA J | 1631 | §102§103 | Final Rejection | — | Pending | Jan 05, 2023 |
| 18148991 | SYSTEMS AND METHODS FOR PREDICTING, DETECTING, AND MONITORING OF ACUTE ILLNESS | Evidation Health, Inc. | EVANS, ASHLEY ELIZABETH | 3687 | §103 | Non-Final OA | 16d overdue | Pending | Dec 30, 2022 |
| 18148227 | PROCESS FOR MANUFACTURING AN ELECTRICALLY CONDUCTING DEVICE FROM LIGNOCELLULOSIC MATERIAL | SAS Woodoo | SHEWAREGED, BETELHEM | 1785 | §103§112 | Non-Final OA | 11d overdue | Pending | Dec 29, 2022 |
| 18003835 | COMPOSITIONS FOR GENOME EDITING AND METHODS OF USE THEREOF | Cibus Biotechnologies, Inc. | TAKENAKA, RISA | 1632 | §112 | Non-Final OA | 27d | Pending | Dec 29, 2022 |
| 18147556 | DEEP LEARNING SUPER-RESOLUTION TRAINING FOR ULTRA LOW-FIELD MAGNETIC RESONANCE IMAGING | Neuro42 Inc. | FRITH, SEAN A | 3798 | §102§103 | Final Rejection | — | Pending | Dec 28, 2022 |
| 18069585 | RECOMBINANT MODIFIED FIBROBLAST GROWTH FACTORS AND THERAPEUTIC USES THEREOF | Trefoil Therapeutics, Inc. | DEBERRY, REGINA M | 1647 | §103 | Final Rejection | 33d | Pending | Dec 21, 2022 |
| 18001898 | PARALLEL ANALYSIS OF INDIVIDUAL CELLS FOR RNA EXPRESSION AND DNA FROM TARGETED TAGMENTATION BY SEQUENCING | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD | PHAM, KHAI QUYNH TIEN | 1684 | §103 | Non-Final OA | — | Pending | Dec 15, 2022 |
| 18065103 | OTOSCOPE SEAL DEVICES AND METHODS | Otonexus Medical Technologies, Inc. | MELHUS, BENJAMIN S | 3791 | §103 | Final Rejection | — | Pending | Dec 13, 2022 |
| 18009612 | SYSTEMS AND DEVICES FOR CONTROLLED DRUG DELIVERY | BEXSON BIOMEDICAL, INC. | PONTON, JAMES D | 3783 | §102§103§112 | Non-Final OA | 35d | Pending | Dec 09, 2022 |
| 18064181 | CELLULAR GLYCOSAMINOGLYCAN COMPOSITIONS AND METHODS OF MAKING AND USING | Tega Therapeutics, Inc. | FRONDA, CHRISTIAN L | 1652 | §103§112Other | Final Rejection | 45d overdue | Pending | Dec 09, 2022 |
| 18061333 | METHODS AND SYSTEMS FOR DROPLET MANIPULATION | Volta Labs, Inc. | PARISI, JESSICA DANIELLE | 1684 | §103 | Final Rejection | 91d overdue | Pending | Dec 02, 2022 |
| 18061310 | METHODS AND SYSTEMS FOR IMPROVING AN ESTIMATION OF A PROPERTY OF A QUANTUM STATE | 1QB Information Technologies Inc. | VASQUEZ, MARKUS A | 2121 | §103§112 | Final Rejection | — | Pending | Dec 02, 2022 |
| 18059370 | METHODS OF CAPTURING CELL-FREE METHYLATED DNA AND USES OF SAME | Sinai Health System | LU, FRANK WEI MIN | 1683 | §102§103§112DP | Non-Final OA | — | Pending | Nov 28, 2022 |
| 17999358 | ENHANCEMENT OF PRODUCTIVITY IN C3 PLANTS | Oxford University Innovation Limited | STOCKDALE, JESSICA NICOLE | 1663 | §101§102§103§112 | Non-Final OA | — | Pending | Nov 18, 2022 |
| 18054810 | SYSTEMS AND METHODS FOR ROBOTIC ENDOSCOPIC SUBMUCOSAL DISSECTION | Noah Medical Corporation | BOICE, JAMES EDWARD | 3795 | §103 | Final Rejection | 87d overdue | Pending | Nov 11, 2022 |
| 17998135 | TARGETED NEK7 INHIBITION FOR MODULATION OF THE NLRP3 INFLAMMASOME | Halia Therapeutics, Inc. | NOLAN, JASON MICHAEL | 1623 | §112 | Final Rejection | — | Pending | Nov 07, 2022 |
| 17997688 | COMPOSITIONS COMPRISING ANTI-VEGF AND NANOPARTICLES AND METHODS OF USING THE SAME FOR THE TREATMENT OF ABNORMAL OR EXCESSIVE ANGIOGENESIS | Cellviva, Inc. | LOCKARD, JON MCCLELLAND | 1647 | §102§103§112 | Non-Final OA | — | Pending | Nov 01, 2022 |
| 17969052 | METHODS AND SYSTEMS FOR REMOTE CONTROLLED VEHICLE | Rotor Technologies, Inc. | REDA, MATTHEW J | 3665 | §103 | Non-Final OA | 27d | Pending | Oct 19, 2022 |
| 18046787 | MESENCHYMAL STEM CELL THERAPIES | Factor Bioscience Inc. | FOX, ALLISON M | 1633 | §102§103§112 | Non-Final OA | — | Pending | Oct 14, 2022 |
| 18046125 | COMPOSITIONS AND METHODS FOR TREATMENT OF SKIN CONDITIONS | Epitop, Inc. | LEE, WILLIAM Y | 1623 | DP | Non-Final OA | — | Pending | Oct 12, 2022 |
| 17964399 | MORTAL PLURIPOTENT STEM CELLS | Accelerated Biosciences Corp. | NOBLE, MARCIA STEPHENS | 1632 | §101 | Non-Final OA | 28d | Pending | Oct 12, 2022 |
| 17963651 | SYSTEMS AND METHODS FOR ACCESS MANAGEMENT AND CLUSTERING OF GENOMIC, PHENOTYPE, AND DIAGNOSTIC DATA | Ix Layer Inc. | MISIASZEK, AMBER ALTSCHUL | 3682 | §101 | Final Rejection | 111d overdue | Pending | Oct 11, 2022 |
| 17938570 | METHOD, KIT AND SYSTEM FOR SYNCHRONOUS PRENATAL DETECTION OF CHROMOSOMAL ANEUPLOIDY AND MONOGENIC DISEASE | Beijing Biobiggen Technology Co., Ltd. | KAPUSHOC, STEPHEN THOMAS | 1683 | §103 | Non-Final OA | — | Pending | Oct 06, 2022 |
| 17917472 | NUCLEIC ACID CONSTRUCTS COMPRISING GENE EDITING MULTI-SITES | Io Biosciences, Inc. | ALLEN, SARAH ELIZABETH | 1637 | §101§102§103§112Other | Non-Final OA | 30d overdue | Pending | Oct 06, 2022 |
| 17934945 | PHARMACOLOGY OF VISUAL CYCLE MODULATORS | Acucela Inc. | HUANG, GIGI GEORGIANA | 1613 | Other | Final Rejection | 55d | Pending | Sep 23, 2022 |
| 17932244 | SYSTEMS AND METHODS OF DETECTING A RISK OF ALZHEIMER'S DISEASE USING A CIRCULATING-FREE MRNA PROFILING ASSAY | Superfluid Dx, Inc. | HOPPE, EMMA RUTH | 1683 | §101§103§112 | Non-Final OA | — | Pending | Sep 14, 2022 |
| 17930840 | STEM CELL STIMULATING COMPOSITIONS AND METHODS | Medicell Technologies, LLC | YU, HONG | 1614 | §103Other | Non-Final OA | 32d overdue | Pending | Sep 09, 2022 |
| 17930842 | STEM CELL STIMULATING COMPOSITIONS AND METHODS | Medicell Technologies, LLC | YU, HONG | 1614 | §103 | Final Rejection | — | Pending | Sep 09, 2022 |
| 17905911 | Engineered PlyAB Nanopores and Uses Thereof | Rijksuniversiteit Groningen | LEE, JAE W | 1656 | §102§112 | Non-Final OA | 33d | Pending | Sep 08, 2022 |
| 17901573 | SCALABLE BIOREACTOR SYSTEMS AND RELATED METHODS OF USE | Mission Barns, Inc. | HURST, JONATHAN M | 1799 | §102§103 | Non-Final OA | 14d | Pending | Sep 01, 2022 |
| 17896355 | METHODS AND SYSTEMS FOR DETERMINING ANCESTRAL RELATEDNESS | Embark Veterinary, Inc. | AUGER, NOAH ANDREW | 1687 | §101§112Other | Non-Final OA | 34d | Pending | Aug 26, 2022 |
| 17822206 | METHODS AND SYSTEMS FOR MACHINE LEARNING-POWERED IDENTIFICATION OF CANCER DIAGNOSES AND DIAGNOSIS DATES FROM ELECTRONIC HEALTH RECORDS | Sema4 Opco, Inc. | SHELDEN, BION A | 3685 | §101§103 | Final Rejection | — | Pending | Aug 25, 2022 |
| 17894885 | OPHTHALMIC COMPOSITION | Sydnexis, Inc. | LEE, WILLIAM Y | 1623 | §103DP | Final Rejection | — | Pending | Aug 24, 2022 |
| 17894884 | OPHTHALMIC COMPOSITION | Sydnexis, Inc. | LEE, WILLIAM Y | 1623 | §103Other | Final Rejection | 55d | Pending | Aug 24, 2022 |
| 17882009 | MICRORNA COMPOSITIONS AND METHODS OF USE | New York R&D Center For Translational Medicine And Therapeutics, Inc. | VYAS, KEYUR ANILKUMAR | 1637 | §103§112 | Non-Final OA | 5d overdue | Pending | Aug 05, 2022 |
| 17760298 | THERAPEUTIC COMBINATIONS COMPRISING A RAF INHIBITOR FOR USE IN TREATING BRAF MUTANT NSCLC | Novartis AG | ROBINSON, MIKHAIL O'DONNEL | 1627 | §103 | Final Rejection | 58d overdue | Pending | Aug 05, 2022 |
| 17880013 | ACOUSTIC OTOSCOPE | Otonexus Medical Technologies, Inc. | DOUGHERTY, SEAN PATRICK | 3791 | §102§103 | Final Rejection | 56d | Pending | Aug 03, 2022 |
| 17759681 | COMBINATIONS OF EGFR INHIBITORS AND ROR1 INHIBITORS FOR THE TREATMENT OF CANCER | Ho'Ola Therapeutics Inc. | CHASE, CAROL ANN | 1646 | §103 | Non-Final OA | — | Pending | Jul 28, 2022 |
| 17795204 | COMPOSITIONS FOR THE TREATMENT OF ANGIOLIPOMA | Raziel Therapeutics Ltd. | CHICKS, ASHLI ARIANA | 1626 | §103Other | Non-Final OA | — | Pending | Jul 25, 2022 |
| 17871274 | LOW MOLECULAR WEIGHT PROTEIN COMPOSITIONS | Advance International Inc. | ZILBERING, ASSAF | 1792 | §103§112 | Non-Final OA | 52d overdue | Pending | Jul 22, 2022 |
| 17813889 | LONG-ACTING VEGF INHIBITORS FOR INTRAOCULAR NEOVASCULARIZATION | The Regents of the University of California | FONTAINHAS, AURORA M | 1675 | §103 | Non-Final OA | — | Pending | Jul 20, 2022 |
| 17866522 | Microbial Conversion of CO2 and Other C1 Substrates to Vegan Nutrients, Fertilizers, Biostimulants, and Systems for Accelerated Soil Carbon Sequestration | Kiverdi, Inc. | UNDERDAHL, THANE E | 1699 | §102§103Other | Final Rejection | 1d overdue | Pending | Jul 17, 2022 |
| 17864285 | ENZYME DELIVERY SYSTEMS AND METHODS OF PREPARATION AND USE | Curemark, LLC | DUTT, ADITI | 1675 | §103DP | Final Rejection | — | Pending | Jul 13, 2022 |
| 17790797 | METHODS AND COMPOSITIONS FOR PRODUCTION OF XENOGENEIC ISLET CELLS AND TREATMENT OF INSULIN-RESISTANT OR -DEFICIENT CONDITIONS WITH THE SAME | Hangzhou Qihan Biotechnology Co., Ltd. | NOBLE, MARCIA STEPHENS | 1632 | §112 | Final Rejection | 9d | Pending | Jul 05, 2022 |
| 17846288 | Compositions and Methods for Simultaneously Modulating Expression of Genes | Versameb AG | WHITEMAN, BRIAN A | 1636 | §102Other | Non-Final OA | 29d | Pending | Jun 22, 2022 |
| 17841267 | COMBINATIONS OF FLAVIVIRUS PROTEINS, PEPTIDE SEQUENCES, EPITOPES, AND METHODS AND USES THEREOF | La Jolla Institute For Immunology | CHEN, STACY BROWN | 1672 | §101§102§103§112 | Non-Final OA | 154d overdue | Pending | Jun 15, 2022 |
| 17784841 | OPHTHALMIC COMPOSITIONS COMPRISING D2O | Sydnexis, Inc. | KENYON, JOHN S | 1625 | §103Other | Non-Final OA | 1d overdue | Pending | Jun 13, 2022 |
| 17782560 | GLP2 RECEPTOR AGONISTS AND METHODS OF USE | The Scripps Research Institute | HA, JULIE | 1654 | §112 | Non-Final OA | — | Pending | Jun 03, 2022 |
| 17782010 | CELL INJECTION PRINTING WITH A COAXIAL NEEDLE | Scripps Health | CARPENTER, WILLIAM R | 3783 | §102§103 | Non-Final OA | 42d overdue | Pending | Jun 02, 2022 |
| 17780227 | SYSTEMS AND DEVICES FOR SAMPLE PREPARATION AND ANALYTE DETECTION | Nucleix Ltd. | BRAZIN, JACQUELINE | 1798 | §103 | Final Rejection | 55d | Pending | May 26, 2022 |
| 17752807 | METHODS OF CAPTURING IMAGES AND MAKING GARMENTS | Bit Body, Inc. | THIRUGNANAM, GANDHI | 2672 | §112Other | Final Rejection | — | Pending | May 24, 2022 |
| 17751106 | TISSUE ARRAY PRINTING | Scripps Health | CHIDIAC, NICHOLAS J | 1744 | §103 | Non-Final OA | — | Pending | May 23, 2022 |
| 17777757 | Artificial nanopores and uses and methods relating thereto | Rijksuniversiteit Groningen | GERIDO, DWAN A | 1797 | §102§103 | Final Rejection | 23d | Pending | May 18, 2022 |
| 17745456 | ANTI-TCR ANTIBODY MOLECULES AND USES THEREOF | Marengo Therapeutics, Inc. | PETERS, ALEC JON | 1641 | §112 | Final Rejection | — | Pending | May 16, 2022 |
| 17739526 | GENE EXPRESSION SIGNATURE OF ENDOMETRIAL SAMPLES FROM WOMEN WITH AND WITHOUT ENDOMETRIOSIS | Endometrics Ltd. | CASH, KAILEY ELIZABETH | 1683 | §101§112 | Final Rejection | 32d overdue | Pending | May 09, 2022 |
| 17772832 | METHODS FOR THE CHARACTERIZATION OF FLUID | NextGen Jane, Inc. | BICKHAM, DAWN MARIE | 1685 | §101§102§112 | Non-Final OA | 61d | Pending | Apr 28, 2022 |
| 17770807 | SAMPLE PREPARATION AND SEQUENCING ANALYSIS FOR REPEAT EXPANSION DISORDERS AND SHORT READ DEFICIENT TARGETS | Jumpcode Genomics, Inc. | BUCHANAN, BAILEY CHEYENNE | 1682 | §101§102§103§112 | Final Rejection | 49d overdue | Pending | Apr 21, 2022 |
| 17770803 | DE-NOVO K-MER ASSOCIATIONS BETWEEN MOLECULAR STATES | Jumpcode Genomics, Inc. | VANN-OJUEKAIYE, KENDRA RAYCHELL | 1682 | §103 | Final Rejection | 5d overdue | Pending | Apr 21, 2022 |
| 17721831 | OPHTHALMIC COMPOSITION | Sydnexis, Inc. | TRAN, ERIC | 1629 | §103 | Non-Final OA | 8d overdue | Pending | Apr 15, 2022 |
| 17719042 | INHALABLE IMATINIB FORMULATION | Inaya Therapeutics, Inc. | LANDAU, SHARMILA GOLLAMUDI | 1653 | §103 | Final Rejection | 107d overdue | Pending | Apr 12, 2022 |
| 17715772 | INTERACTIVE MEDIA | Ta-Da! Language Productions, Inc. | POLLOCK, ZACHARY JOSEPH | 3715 | §102§103 | Final Rejection | 43d overdue | Pending | Apr 07, 2022 |
| 17766946 | METHODS AND SYSTEMS FOR ANALYZING COMPLEX GENOMIC REGIONS | Rprd Diagnostics, LLC | CASH, KAILEY ELIZABETH | 1683 | §103Other | Non-Final OA | — | Pending | Apr 06, 2022 |
| 17706163 | SYSTEMS AND METHODS OF USING SELF-ATTENTION DEEP LEARNING FOR IMAGE ENHANCEMENT | Subtle Medical, Inc. | GEBRESLASSIE, WINTA | 2677 | §103 | Final Rejection | — | Pending | Mar 28, 2022 |
| 17761696 | COMPOSITIONS AND METHODS FOR TEMPLATE-FREE DOUBLE STRANDED GEOMETRIC ENZYMATIC NUCLEIC ACID SYNTHESIS | Derek Stemple | PARISI, JESSICA DANIELLE | 1684 | §103§112 | Final Rejection | 13d | Pending | Mar 18, 2022 |
| 17761866 | METHOD AND SYSTEM FOR TARGETED NUCLEIC ACID SEQUENCING | Jumpcode Genomics, Inc. | GUSSOW, ANNE | 1600 | §102§103§112 | Final Rejection | — | Pending | Mar 18, 2022 |
| 17681560 | OPHTHALMIC COMPOSITION | Sydnexis, Inc. | SIMMONS, CHRIS E | 1622 | §103Other | Final Rejection | 23d overdue | Pending | Feb 25, 2022 |
| 17638760 | HEPARIN AND HEPARAN SULFATE FROM MODIFIED MAST CELLS AND METHODS OF MAKING AND USING | Tega Therapeutics, Inc. | SABILA, MERCY HELLEN | 1654 | DP | Non-Final OA | 60d overdue | Pending | Feb 25, 2022 |
| 17637737 | COMPOSITIONS FOR MONOCYTE AND MACROPHAGE POLARIZATION AND METHODS OF USE | Orbsen Therapeutics Limited | ABBOTT, KODYE LEE | 1634 | §103 | Final Rejection | 6d | Pending | Feb 23, 2022 |
| 17587643 | SYSTEMS AND METHODS FOR ASSESSING A TARGET MOLECULE | Axbio Inc. | LEE, JAE W | 1656 | §103 | Non-Final OA | 21d | Pending | Jan 28, 2022 |
| 17584892 | MULTISPECIFIC AND MULTIFUNCTIONAL MOLECULES AND USES THEREOF | Marengo Therapeutics, Inc. | CANELLA, KAREN A | 1643 | §112DP | Non-Final OA | 16d | Pending | Jan 26, 2022 |
| 17629744 | IL-2 CYTOKINE PRODRUGS COMPRISING A CLEAVABLE LINKER | Trutino Biosciences Inc. | PATTERSON, SARAH COOPER | 1675 | §103§112 | Final Rejection | — | Pending | Jan 24, 2022 |
| 17578149 | METHODS OF TREATING CONGENITAL ADRENAL HYPERPLASIA | Spruce Biosciences, Inc. | LEE, WILLIAM Y | 1623 | §103DP | Final Rejection | — | Pending | Jan 18, 2022 |
| 17558865 | Systems and Methods for Inferring Taxonomies in Manufacturing Processes | Oden Technologies Ltd. | ROBINSON, GRETA LEE | 2163 | §101§102§103§112 | Non-Final OA | 11d overdue | Pending | Dec 22, 2021 |
| 17556068 | METHODS AND SYSTEMS FOR IDENTIFYING TARGET GENES | Algen Biotechnologies, Inc. | MINCHELLA, KAITLYN L | 1685 | §112Other | Final Rejection | 2d overdue | Pending | Dec 20, 2021 |
| 17554181 | SYSTEMS FOR SAMPLE ANALYSIS | Biomeme, Inc. | GIAMMONA, FRANCESCA FILIPPA | 1681 | §103§112Other | Non-Final OA | 3d overdue | Pending | Dec 17, 2021 |
| 17620650 | METHODS OF PROMOTING VASCULOGENESIS | BIOTISSUE HOLDINGS INC. | JOHNSON, ALLISON MARIE | 1638 | §112 | Non-Final OA | — | Pending | Dec 17, 2021 |
| 17552702 | SYSTEMS AND METHODS FOR PROCESSING STOOL SAMPLES | Biomesense, Inc. | SIMMONS, VALERIE MICHELLE | 1758 | §103 | Final Rejection | — | Pending | Dec 16, 2021 |
| 17549232 | INFUSION DEVICE FOR CONTINUOUS GLUCOSE MONITORING | Pacific Diabetes Technologies Inc. | RITCHIE, HADEN MATTHEW | 3783 | §103 | Non-Final OA | — | Pending | Dec 13, 2021 |
| 17616278 | TUMOR ACTIVATED T CELL ENGAGERS AND METHODS OF USE THEREOF | Janux Therapeutics, Inc. | SHUPE, ELIZABETH A | 1643 | §103Other | Non-Final OA | — | Pending | Dec 03, 2021 |
| 17616244 | SYSTEMS AND METHODS FOR DETERMINING SEQUENCE | Xgenomes Corp. | ANDERSON-FEARS, KEENAN NEIL | 1687 | §101§102§103 | Non-Final OA | 77d overdue | Pending | Dec 03, 2021 |
| 17611838 | CELLS, TISSUES, ORGANS, AND/OR ANIMALS HAVING ONE OR MORE MODIFIED GENES FOR ENHANCED XENOGRAFT SURVIVAL AND/OR TOLERANCE | Hangzhou Qihan Biotechnology Co., Ltd. | BATES, KEENAN ALEXANDER | 1631 | §103Other | Final Rejection | 27d | Pending | Nov 16, 2021 |
| 17518016 | BIOMARKERS FOR DIAGNOSING ALZHEIMER'S DISEASE | Seer, Inc. | TRAN, CHAU NGUYEN BICH | 1677 | §103§112 | Final Rejection | 5d overdue | Pending | Nov 03, 2021 |
| 17606514 | METHOD FOR THE TREATMENT OF PERIODONTAL DISEASE USING CHARACTERIZED MESENCHYMAL STEM CELL GROWTH FACTORS AND EXOSOMES | Direct Biologics, LLC | KIM, TAEYOON | 1631 | §103 | Non-Final OA | — | Pending | Oct 26, 2021 |
| 17497373 | TISSUE GRASPING DEVICES AND RELATED METHODS | Medfree, Inc. | PRONE, CHRISTOPHER D | 3774 | §102§103§112 | Non-Final OA | 169d overdue | Pending | Oct 08, 2021 |
| 17490160 | METHOD OF DETERMINING PERCENTAGE OF IMMUNE CELL TYPES IN A SALIVA SPECIMEN | Tru Diagnostics, Inc. | JOHANSEN, PETER N. | 1644 | §101§102§103§112 | Non-Final OA | 70d | Pending | Sep 30, 2021 |
| 17491036 | PERIVASCULAR ANTI-INFLAMMATORY THERAPY FOR VENOUS THROMBOSIS | Mercator Medsystems, Inc. | KOO, BENJAMIN K | 3783 | §103 | Non-Final OA | — | Pending | Sep 30, 2021 |
| 17478571 | SYSTEMS, METHODS AND DEVICES FOR MONITORING, EVALUATING AND PRESENTING HEALTH RELATED INFORMATION, INCLUDING RECOMMENDATIONS | January, Inc. | HRANEK, KAREN AMANDA | 3684 | §101§103 | Final Rejection | 15d overdue | Pending | Sep 17, 2021 |
| 17406847 | MODIFIED IL-18 POLYPEPTIDES AND USES THEREOF | Bright Peak Therapeutics AG | FORD, VANESSA L | 1674 | §103§112 | Final Rejection | 73d overdue | Pending | Aug 19, 2021 |
| 17402318 | MULTIFUNCTIONAL MOLECULES THAT BIND TO T CELLS AND USES THEREOF TO TREAT AUTOIMMUNE DISORDERS | Marengo Therapeutics, Inc. | SHUPE, ELIZABETH A | 1643 | §112DP | Non-Final OA | — | Pending | Aug 13, 2021 |
| 17402365 | INTEGRATED SLEW DRIVES FOR ACTUATION OF TELECOMMUNICATION SYSTEMS AND OTHERS | Kinematics, LLC | RUSHING, JR, BOBBY | 3618 | §103 | Final Rejection | 28d overdue | Pending | Aug 13, 2021 |
| 17399041 | OPTIMIZED VACCINE COMPOSITIONS AND METHODS FOR MAKING THE SAME | Centivax, Inc. | FOLEY, SHANON A | 1671 | §103 | Final Rejection | — | Pending | Aug 10, 2021 |
| 17427192 | METHODS AND COMPOSITIONS FOR DEVELOPING TARGET SPECIFIC EXOSOME AND GROWTH FACTOR PRODUCTS | Direct Biologics, LLC | GOLDBERG, JEANINE ANNE | 1682 | §103§112DP | Non-Final OA | 126d overdue | Pending | Jul 30, 2021 |
| 17427046 | COMPOSITIONS AND METHODS FOR PRODUCING FOOD PRODUCTS WITH RECOMBINANT ANIMAL PROTEIN | Bond Pet Foods, Inc. | ROBINSON, HOPE A | 1652 | §112DP | Non-Final OA | — | Pending | Jul 29, 2021 |
| 17380563 | SYSTEMS AND METHODS FOR ACCESS MANAGEMENT AND CLUSTERING OF GENOMIC OR PHENOTYPE DATA | Ix Layer Inc. | VANNI, GEORGE STEVEN | 1686 | §101§103§112DP | Non-Final OA | — | Pending | Jul 20, 2021 |
| 17369499 | SYSTEMS AND METHODS FOR CLASSIFYING, PRIORITIZING AND INTERPRETING GENETIC VARIANTS AND THERAPIES USING A DEEP NEURAL NETWORK | Deep Genomics Incorporated | ANDERSON-FEARS, KEENAN NEIL | 1687 | §101§103Other | Non-Final OA | 60d overdue | Pending | Jul 07, 2021 |
| 17420500 | ISOLATION AND USE OF AUTOGENOUS PLATELET DERIVED EXOSOMES | Direct Biologics, LLC | SCHUBERG, LAURA J | 1631 | §103 | Non-Final OA | — | Pending | Jul 02, 2021 |
| 17418342 | METHODS AND COMPOSITIONS FOR TREATING SKIN AND HAIR DISORDERS | Direct Biologics LLC | ROGERS, ERIC JASON | 1638 | §102§103§112DP | Non-Final OA | — | Pending | Jun 25, 2021 |
| 17291580 | TWO-GENE VECTORS FOR GENERATING CAR-T CELLS AND USES THEREOF | Iaso Biotherapeutics Usa Limited | AEDER, SEAN E | 1642 | §103§112 | Non-Final OA | 80d overdue | Pending | May 05, 2021 |
| 17291070 | METHODS OF CELLULAR REPROGRAMMING | BIOTISSUE HOLDINGS INC. | BATES, KEENAN ALEXANDER | 1631 | §103§112 | Non-Final OA | — | Pending | May 04, 2021 |
| 17289992 | CYSTEINE ENGINEERED ANTIBODY-DRUG CONJUGATES WITH PEPTIDE-CONTAINING LINKERS | Mersana Therapeutics, Inc. | BUNNER, BRIDGET E | 1647 | §103§112Other | Non-Final OA | 22d | Pending | Apr 29, 2021 |
| 17243452 | CELL-FREE RNA LIBRARY PREPARATIONS | Superfluid Dx, Inc. | TSAY, MARSHA M | 1656 | §103 | Final Rejection | 18d overdue | Pending | Apr 28, 2021 |
| 17222419 | COMPOSITIONS AND METHODS FOR POST-OPERATIVE OCULAR CARE | Ocular Science, Inc. | RODRIGUEZ, RAYNA B | 1628 | §103 | Final Rejection | 66d overdue | Pending | Apr 05, 2021 |
| 17196825 | METHOD AND SYSTEM FOR ESTIMATING PHYSICAL QUANTITIES OF A PLURALITY OF MODELS USING A SAMPLING DEVICE | 1QB Information Technologies Inc. | FIGUEROA, KEVIN W | 2124 | §101 | Non-Final OA | 72d overdue | Pending | Mar 09, 2021 |
| 17167949 | MICROFLUIDIC DEVICES AND USES THEREOF | Signal Biosystems, Inc. | GORDON, BRIAN R | 1798 | §103§112 | Non-Final OA | 2d overdue | Pending | Feb 04, 2021 |
| 17059994 | LOW-PROFILE MULTI-AGENT INJECTION SYSTEM AND METHODS | Presage Biosciences, Inc. | VARGAS, ANNA ELIZABETH | 3783 | §103 | Final Rejection | 8d overdue | Pending | Nov 30, 2020 |
| 17055513 | CRYSTALLINE FORMS OF 1-(ACYLOXY)-ALKYL CARBAMATE DRUG CONJUGATES OF NAPROXEN AND PREGABALIN | Xgene Pharmaceutical Inc. | MOU, LIYUAN | 1628 | §103 | Final Rejection | 72d overdue | Pending | Nov 13, 2020 |
| 17031584 | MICROELECTRODE ARRAY AND METHODS OF FABRICATING SAME | Paradromics Inc. | LEE, DAVINA EN-YIN | 3794 | §103 | Final Rejection | — | Pending | Sep 24, 2020 |
| 16939921 | MOLECULAR DETECTION USING LIGATION AMPLIFICATION | Aratome, LLC | SCHLOOP, ALLISON ELIZABETH | 1683 | §112 | Non-Final OA | — | Pending | Jul 27, 2020 |
| 16960543 | HETERODUPLEX NUCLEIC ACID MOLECULES AND USES THEREOF | Atrium Therapeutics, Inc. | VIVLEMORE, TRACY ANN | 1638 | §112Other | Non-Final OA | 21d | Pending | Jul 07, 2020 |
| 16874533 | COMPOSITIONS AND METHODS FOR INCREASING THE POLLINATION PERFORMANCE OF BEES | CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS | NEAGU, IRINA | 1629 | §103 | Non-Final OA | — | Pending | May 14, 2020 |
| 16763933 | SYSTEMS, DEVICES, FORMULATIONS AND METHODS FOR CONTROLLED DRUG DELIVERY | BEXSON BIOMEDICAL, INC. | SCHMIDT, EMILY LOUISE | 3783 | §103 | Non-Final OA | 44d overdue | Pending | May 13, 2020 |
| 16760522 | CANCER DETECTION, CLASSIFICATION, PROGNOSTICATION, THERAPY PREDICTION AND THERAPY MONITORING USING METHYLOME ANALYSIS | Sinai Health System | SITTON, JEHANNE SOUAYA | 1682 | §103 | Final Rejection | 34d | Pending | Apr 30, 2020 |
| 16718092 | NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF | Atrium Therapeutics, Inc. | CANELLA, KAREN A | 1643 | §103 | Final Rejection | 118d overdue | Pending | Dec 17, 2019 |
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