Prosecution Insights
Prosecution Insights
Technology areas: Biotechnology & Pharmaceuticals • Medical Devices & Mechanical Engineering
381 pending office actions • 185 clients • 319 examiners • 116 art units • 0 of 381 (0%) have an AI response strategy ready
GOODWIN PROCTER LLP has a history in the Biotechnology & Pharmaceuticals technology area, having handled 12315 career applications. This volume of 12315 applications establishes the firm as a participant in this sector. Currently, the firm is managing a docket of 322 pending office actions, reflecting its large-scale operations.
The firm maintains a resolved allowance rate of 74.52 percent. This outcome is reached with an average of 3.51 office actions per allowance. This 3.51 average indicates a prosecution process that typically requires multiple rounds of interaction with the patent office to secure a grant in the Biotechnology & Pharmaceuticals field. The 74.52 percent allowance rate across 12315 career applications provides a benchmark for their success in this technical area.
With 322 pending office actions, the firm continues to be active in patent prosecution. The 12315 career applications provide a dataset for evaluating their long-term performance. Practitioners can use the 74.52 percent resolved allowance rate and the 3.51 average office actions per allowance to evaluate the firm's typical prosecution path and success rate for biotech and pharmaceutical patents.
Based on the USPTO statutory response window for each pending office action. 124 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.
Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 124 of the docket's apps have a known mailing date.
Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.
| Bucket | Cases |
|---|---|
| §101 only | 2 (1%) |
| §101 + other | 49 (13%) |
| §103 only | 78 (20%) |
| §102 only | 12 (3%) |
| §112 only | 25 (7%) |
| Double-patenting only | 16 (4%) |
| Double-patenting + other | 54 (14%) |
| Multi-statute (no §101) | 138 (36%) |
| No statute on record | 7 (2%) |
How the docket's pending cases split across USPTO tech-center bands.
Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.
| Examiner | Apps on this docket | Allow rate | Interview lift |
|---|---|---|---|
| WANG, JING | 4 | 100.0% | +0.0% |
| GOLLAMUDI, NEERAJA | 4 | 72.7% | +39.9% |
| HASAN, KHALEDA B | 4 | 59.4% | +49.5% |
| GODDARD, LAURA B | 3 | 50.9% | +13.5% |
| KALISZEWSKI, ALINA ROSE | 3 | 84.4% | +23.8% |
| SMALE, AVERY E | 3 | 74.2% | +21.2% |
| SWANSON, LEAH JENNINGS | 3 | 65.5% | +38.3% |
| BAHENA, CHRISTIE L. | 3 | 68.2% | +23.5% |
| PONTON, JAMES D | 3 | 79.9% | +32.7% |
| JAVANMARD, SAHAR | 3 | 64.8% | +34.1% |
Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 2 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18568165 | VACUUM SYSTEM FOR A MASS SPECTROMETER | WANG, JING | 38d overdue |
| 17998012 | AN ATMOSPHERIC PRESSURE IONISATION SOURCE | KALISZEWSKI, ALINA ROSE | — |
Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 18612960 | Bispecific Asymmetric Heterodimers Comprising Anti-CD3 Constructs | HUYNH, PHUONG N | 238d overdue |
| 18145772 | SARS-COV-2 SERUM ANTIBODY PROFILING | ZOU, NIANXIANG | 162d overdue |
| 17800958 | METHODS AND COMPOSITIONS FOR MODULATING ARGININE LEVELS IN IMMUNE CELLS | DHAR, MATASHA | 147d overdue |
| 17879923 | 6-MEMBERED AZA-HETEROCYCLIC CONTAINING DELTA-OPIOID RECEPTOR MODULATING COMPOUNDS, METHODS OF USING AND MAKING THE SAME | JAVANMARD, SAHAR | 147d overdue |
| 17157043 | Dynamically Changing Promotions Displayed on a Mobile Device and Measuring The Benefit Thereof | OSMAN BILAL AHMED, AFAF | 147d overdue |
| 18085792 | THERAPEUTIC COMPOSITIONS, COMBINATIONS, AND METHODS OF USE | JAVANMARD, SAHAR | 142d overdue |
| 18042375 | NEBULIZER DEVICE OPTIMIZATION FOR IMPROVED AEROSOL PARAMETERS AND USES THEREOF | PINDERSKI, JACQUELINE M | 104d overdue |
| 17552935 | METHODS, MEDIUMS, AND SYSTEMS FOR BUILDING AND EXECUTING A CHROMATOGRAPHY WORKFLOW | GAVIN, KRISTIN ELIZABETH | 99d overdue |
Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.
| App # | Title | Examiner | Due in |
|---|---|---|---|
| 17879923 | 6-MEMBERED AZA-HETEROCYCLIC CONTAINING DELTA-OPIOID RECEPTOR MODULATING COMPOUNDS, METHODS OF USING AND MAKING THE SAME | JAVANMARD, SAHAR | 147d overdue |
| 18085792 | THERAPEUTIC COMPOSITIONS, COMBINATIONS, AND METHODS OF USE | JAVANMARD, SAHAR | 142d overdue |
| 18016838 | METHOD FOR CONTROLLING A PROSTHESIS OR ORTHOSIS | BAHENA, CHRISTIE L. | 35d overdue |
| 18246783 | METHOD FOR CONTROLLING A PROSTHETIC FOOT | BAHENA, CHRISTIE L. | 28d overdue |
| 16859544 | FILLING ASSIST MECHANISMS AND KEYED INTERFACES FOR DRUG DELIVERY DEVICES | SWANSON, LEAH JENNINGS | 3d overdue |
| 18386647 | PROGRAMMATIC MEDICAMENT TITRATION WITH A MEDICAMENT DELIVERY DEVICE | SWANSON, LEAH JENNINGS | 14d |
| 16995527 | RATCHET DRIVE FOR ON BODY DELIVERY SYSTEM | SWANSON, LEAH JENNINGS | 14d |
| 18016827 | ORTHOPAEDIC JOINT DEVICE | BAHENA, CHRISTIE L. | 21d |
| Art Unit | Apps |
|---|---|
| 3783 | 38 |
| 1642 | 9 |
| 1618 | 9 |
| 2881 | 9 |
| 1625 | 7 |
| 1635 | 7 |
| 1636 | 7 |
| 1623 | 7 |
| 1626 | 6 |
| 3774 | 6 |
| App # | Title | Client | Examiner | Art Unit | Statutes | Status | Due in | AI | Filed |
|---|---|---|---|---|---|---|---|---|---|
| 19569819 | TRISPECIFIC COMPOSITIONS COMPRISING IL-2, VEGF BINDING DOMAINS, AND PD-1 BINDING DOMAINS | Bright Peak Therapeutics AG | GODDARD, LAURA B | 1642 | §103§112DP | Non-Final OA | — | Pending | Mar 17, 2026 |
| 19548526 | HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF | University of Basel | PERREIRA, MELISSA JEAN | 1618 | §102§103DP | Non-Final OA | — | Pending | Feb 24, 2026 |
| 19545401 | FORMULATIONS OF VIMSELTINIB | Deciphera Pharmaceuticals, LLC | PAK, JOHN D | 1699 | §103§112DP | Final Rejection | — | Pending | Feb 20, 2026 |
| 19544595 | FORMULATIONS OF VIMSELTINIB | Deciphera Pharmaceuticals, LLC | LEE, SIN J | 1613 | §102§103§112 | Final Rejection | — | Pending | Feb 19, 2026 |
| 19434846 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF RADIATION INDUCED TOXICITY | Zydus Lifesciences Limited | OH, TAYLOR V | 1625 | §103 | Final Rejection | — | Pending | Dec 29, 2025 |
| 19432924 | AN IMPROVED PROCESS OF PURIFICATION OF PROTEIN | Kashiv Biosciences, LLC | REGLAS, GEORGIANA C | 1651 | §102 | Final Rejection | — | Pending | Dec 24, 2025 |
| 19432904 | AN IMPROVED PROCESS OF PURIFICATION OF PROTEIN | Kashiv Biosciences, LLC | MCDERMOTT, JEANNIE | 1776 | §103§112Other | Non-Final OA | — | Pending | Dec 24, 2025 |
| 19412192 | HALOBETASOL PROPIONATE-LIDOCAINE FORMULATIONS | Citius Pharmaceuticals, Inc. | HEITMEIER, KENDALL NICOLE | 1621 | §101§103§112 | Non-Final OA | — | Pending | Dec 08, 2025 |
| 19397828 | TREATMENT OF DIABETIC RETINOPATHY USING ENDOTHELIN RECEPTOR ANTAGONISTS | Perfuse Therapeutics, Inc. | BASQUILL, SEAN M | 1614 | §103 | Final Rejection | — | Pending | Nov 21, 2025 |
| 19353469 | COMPOSITIONS, DEVICES, AND METHODS RELATING TO USE OF AN AMNIOTIC MEMBRANE FETAL TISSUE PRODUCT | BIOTISSUE HOLDINGS INC. | WESTON, ALYSSA G | 1633 | §102§103 | Final Rejection | — | Pending | Oct 08, 2025 |
| 19348728 | ORAL MUCOSAL FORMULATIONS OF ASPIRIN | Aspire Biopharma Holdings, Inc. | SONG, JIANFENG | 1613 | §103DP | Final Rejection | — | Pending | Oct 02, 2025 |
| 19344208 | CRYOGENIC COOLING SYSTEM WITH A RESONANT EXPANDER | R7 Instruments, Inc. | LARGI, MATTHEW THOMAS | 3746 | §102§112 | Final Rejection | — | Pending | Sep 29, 2025 |
| 19338730 | TRANSDERMAL DEXMEDETOMIDINE FOR TREATING AGITATION | Teikoku Pharma Usa, Inc. | HAVLIN, ROBERT H | 1626 | §103DP | Final Rejection | — | Pending | Sep 24, 2025 |
| 19288411 | MULTI-TIERED TESTING FOR TRACKING DISEASE HETEROGENEITY | Flagship Pioneering Innovations Vi, LLC | SKIBINSKY, ANNA | 1635 | §101§103 | Non-Final OA | 50d overdue | Pending | Aug 01, 2025 |
| 19284259 | SYSTEMS AND METHODS FOR DENTAL TREATMENT WITH EKF | T33 Dental, Inc. | GONZALEZ, LEI NMN | 3783 | §103 | Final Rejection | 14d | Pending | Jul 29, 2025 |
| 19220387 | SYSTEMS AND METHODS FOR DETERMINING ASSET IMPORTANCE IN SECURITY RISK MANAGEMENT | Bitsight Technologies, Inc. | MANIWANG, JOSEPH R | DP | Non-Final OA | — | Pending | May 28, 2025 | |
| 19213573 | TRANSDERMAL DELIVERY PATCH FOR TREATING PAIN | Teikoku Pharma Usa, Inc. | GHALI, ISIS A D | 1611 | §103Other | Final Rejection | — | Pending | May 20, 2025 |
| 19211805 | ON-BODY INTERLOCK FOR DRUG DELIVERY DEVICE | Insulet Corporation | STIGELL, THEODORE J | 3783 | §103§112DP | Non-Final OA | — | Pending | May 19, 2025 |
| 19197571 | SYSTEMS AND METHODS FOR DATA STRUCTURE ANALYSIS | Gestalt Tech Corp. | SAMARA, HUSAM TURKI | 2161 | §103 | Final Rejection | 36d overdue | Pending | May 02, 2025 |
| 19196457 | IgE PROTEASES AND USES THEREOF | Seismic Therapeutic, Inc. | DESAI, ANAND U | 1655 | §102§103§112 | Non-Final OA | — | Pending | May 01, 2025 |
| 19180988 | EARLY MEAL DETECTION AND CALORIE INTAKE DETECTION | Insulet Corporation | NGUYEN, HIEP VAN | 3686 | §101§103 | Non-Final OA | — | Pending | Apr 16, 2025 |
| 19171119 | SYSTEM TO CREATE CELLULAR LYSIS AND DELIVER FLUIDS INTRATUMORALLY | Syncromune, Inc. | SHOULDERS, ANNIE LEE | §102§103 | Non-Final OA | — | Pending | Apr 04, 2025 | |
| 19087070 | POLY-DONOR CD4+ T CELLS EXPRESSING IL-10 AND USES THEREOF | Tr1X, Inc. | NGUYEN, QUANG | 1631 | §103§112Other | Non-Final OA | — | Pending | Mar 21, 2025 |
| 19079820 | IMAGE-GUIDED ROBOTIC SYSTEM WITH REMOTE GUIDANCE, IMAGE STEERING, MULTI-PLANE IMAGING, NEEDLE VISUALIZATION ENHANCEMENT, AND CONSTRAINED BACKDRIVING | Mendaera, Inc. | BRUTUS, JOEL F | 3797 | §103 | Final Rejection | 30d overdue | Pending | Mar 14, 2025 |
| 19073748 | SYSTEMS AND METHODS FOR CUSTOMIZING ONLINE GAMING | Magnetic Games AB | ADAMS, CARL | §102§103 | Non-Final OA | — | Pending | Mar 07, 2025 | |
| 19039593 | FABRICATION OF POLYCRYSTALLINE SILICON NITRIDE FIBERS | Bluehalo, LLC | DAIGLER, CHRISTOPHER PAUL | §101§103 | Non-Final OA | — | Pending | Jan 28, 2025 | |
| 19035537 | APPARATUS FOR GLYCEMIC CONTROL | Insulet Corporation | KOLOSOWSKI-GAGER, KATHERINE | 3687 | §101§103 | Final Rejection | 42d overdue | Pending | Jan 23, 2025 |
| 19022962 | METHOD AND SYSTEM FOR ASSET ROUTING | Lob.Com, Inc. | WALLACE, JOHN R | §103Other | Non-Final OA | — | Pending | Jan 15, 2025 | |
| 19013936 | SYSTEMS AND METHODS FOR UNDERGROUND STORAGE OF STORM AND OTHER WATER SOURCES | Underground Industries LLC | TOLEDO-DURAN, EDWIN J | §102§103§112Other | Non-Final OA | — | Pending | Jan 08, 2025 | |
| 19012213 | SYSTEM AND METHOD FOR TREATMENT OF MEDICAL CONDITIONS USING MULTIPLE BLOOD PRESSURE SENSORS | Aktiia SA | YOON, CHANEL J | 3791 | §101§103§112 | Non-Final OA | — | Pending | Jan 07, 2025 |
| 19004969 | LOGGING AND ANALYZING ROBOTIC PICKING DATA | Oxipital AI Inc. | NELESKI, ELIZABETH ROSE | 3658 | §103 | Final Rejection | 14d | Pending | Dec 30, 2024 |
| 18974588 | NINTEDANIB AND NINTEDANIB COMBINATION DRY POWDER COMPOSITIONS AND USES | Avalyn Pharma Inc. | ZHANG SPIERING, DONGXIU | §103§112DP | Non-Final OA | — | Pending | Dec 09, 2024 | |
| 18870188 | SYSTEM AND METHODS FOR PREDICTING GLAUCOMA INCIDENCE AND PROGRESSION USING RETINAL PHOTOGRAPHS | Antinous Technology Company Limited | FUJITA, KATRINA R | §102§103 | Non-Final OA | — | Pending | Nov 27, 2024 | |
| 18958722 | COMPOSITE BUILDING MATERIALS AND METHODS OF MANUFACTURE | Rise Building Products LLC | CHOI, PETER Y | 1786 | §103 | Final Rejection | — | Pending | Nov 25, 2024 |
| 18952889 | NOVEL ANTI-PD-L1 ANTIBODIES | Wuxi Biologics Ireland Limited | ROONEY, NORA MAUREEN | §112Other | Non-Final OA | — | Pending | Nov 19, 2024 | |
| 18945759 | SYSTEMS AND METHODS FOR PATIENT TARGETED THERAPY DEVELOPMENT | Flagship Pioneering Innovations Vi, LLC | PAULS, JOHN A | 3683 | §101§103DP | Final Rejection | 23d overdue | Pending | Nov 13, 2024 |
| 18941986 | 3-(SUBSTITUTED-4-OXOQUINAZOLIN-3(4H)-YL)-3-DEUTERO-PIPERIDINE-2,6-DIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | Deuterx, LLC | WARD, PAUL V | DP | Non-Final OA | — | Pending | Nov 08, 2024 | |
| 18938818 | COMPACT LIQUID CHROMATOGRAPHY SYSTEM PROVIDING THERMAL MANAGEMENT AND DETECTION | Waters Technologies Corporation | SINGER, DAVID L | §103Other | Non-Final OA | — | Pending | Nov 06, 2024 | |
| 18936787 | DOSING REGIMENS FOR THE MOBILIZATION OF HEMATOPOIETIC STEM CELLS | Ensoma, Inc. | PAGUIO FRISING, MICHELLE F | §103§112DP | Non-Final OA | — | Pending | Nov 04, 2024 | |
| 18862402 | METHOD FOR SETTING UP AN ORTHOPAEDIC DEVICE | Ottobock SE & Co. Kgaa | WAGGLE, JR, LARRY E | §102§112 | Non-Final OA | — | Pending | Nov 01, 2024 | |
| 18932353 | MANUALLY OPERATED PUMP ASSEMBLY | Kickstart International, Inc. | PEKARSKAYA, LILYA | 3746 | §102§103 | Final Rejection | — | Pending | Oct 30, 2024 |
| 18860528 | PROLONGED AIR LEAK PERCEPTION | Texas Medical Center | MONTICELLO, WILLIAM THOMAS | 3682 | §101§102 | Non-Final OA | 35d | Pending | Oct 25, 2024 |
| 18925636 | WEARABLE SENSOR HAVING AN ADHESIVE, AND A MANUFACTURING METHOD | Occam Bci, Inc. | XU, JUSTIN | §103 | Non-Final OA | — | Pending | Oct 24, 2024 | |
| 18920112 | ADAPTIVE INTRINSIC LOCK MASS CORRECTION | Micromass UK Limited | GUNBERG, EDWIN C | 2884 | — | Non-Final OA | — | Pending | Oct 18, 2024 |
| 18916566 | PHARMACEUTICAL COMPOSITIONS COMPRISING ANTI-HUMAN TSLP RECEPTOR ANTIBODIES AND METHODS OF USING THE SAME | Upstream Bio, Inc. | DUFFY, PATRICIA ANN | DP | Non-Final OA | — | Pending | Oct 15, 2024 | |
| 18913635 | SYSTEM FOR PURIFICATION OF BIOACTIVE PROTEINS, AND RELATED METHODS | HP Bioengineering, LLC | NGUYEN, BOI-LIEN THI | §102§103§112 | Non-Final OA | — | Pending | Oct 11, 2024 | |
| 18909461 | WEARABLE COMPUTER POINTING APPARATUS | 6Degrees Ltd. | LEIBY, CHRISTOPHER E | 2621 | §103 | Non-Final OA | 11d overdue | Pending | Oct 08, 2024 |
| 18907930 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | Parcus Medical, LLC | BONAPARTE, AMY C | 1692 | §102§103§112Other | Non-Final OA | — | Pending | Oct 07, 2024 |
| 18854263 | TYROSINE KINASE INHIBITORS | University Court Of The University Of Edinburgh | CHAO, ALLEN | 1629 | §103DP | Non-Final OA | — | Pending | Oct 04, 2024 |
| 18853369 | METHOD TO MANUFACTURE BIOFUEL | Sixring Inc. | ROBINSON, RENEE E | §103§112 | Non-Final OA | — | Pending | Oct 01, 2024 | |
| 18852039 | TYK2 INHIBITORS AND USES THEREOF | Alumis Inc. | ROCHELLE, CIERRA MARIE | §103§112DP | Non-Final OA | — | Pending | Sep 27, 2024 | |
| 18850007 | MASS SPECTROMETER HAVING HIGH DUTY CYCLE | Micromass UK Limited | KALISZEWSKI, ALINA ROSE | §103§112 | Non-Final OA | — | Pending | Sep 23, 2024 | |
| 18850020 | MASS SPECTROMETER HAVING HIGH DUTY CYCLE | Micromass UK Limited | WANG, JING | §103§112 | Non-Final OA | — | Pending | Sep 23, 2024 | |
| 18887514 | SPECIALLY FORMULATED COMPOSITIONS OF INHALED NINTEDANIB AND NINTEDANIB SALTS | Avalyn Pharma Inc. | RONEY, CELESTE A | §103§112DP | Non-Final OA | — | Pending | Sep 17, 2024 | |
| 18883710 | ADHESIVE PATCH AND SYSTEM FOR WEARABLE MEDICAL DEVICE | Insulet Corporation | VOKES, KATHLEEN PAIGE | §102§103 | Non-Final OA | — | Pending | Sep 12, 2024 | |
| 18829953 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | The Board Of Regents Of The University Of Texas System | SEAMAN, D MARGARET M | DP | Non-Final OA | — | Pending | Sep 10, 2024 | |
| 18825624 | OBSERVATION AND/OR INSPECTION OF A MATERIAL WEB | Texmag GmbH Vertriebsgesellschaft | HAIDER, SYED | §103§112 | Non-Final OA | — | Pending | Sep 05, 2024 | |
| 18841749 | TRIPLE UPTAKE INHIBITOR FOR THE TREATMENT OF ATYPICAL DEPRESSION | Noema Pharma AG | ARCORIA, PAUL JOSEPH | §102§103 | Non-Final OA | — | Pending | Aug 27, 2024 | |
| 18841235 | MEASURING IONS WITH CHARGE REDUCTION | Micromass UK Limited | WANG, JING | §101§103§112 | Non-Final OA | — | Pending | Aug 23, 2024 | |
| 18804372 | SAFETY CONSTRAINTS FOR A CONTROL ALGORITHM BASED DRUG DELIVERY SYSTEM | Insulet Corporation | GOLLAMUDI, NEERAJA | 3783 | §103§112 | Non-Final OA | — | Pending | Aug 14, 2024 |
| 18799908 | SYSTEMS AND METHODS FOR DETERMINING EVENT SCHEDULES | Recentive Analytics, Inc. | KNIGHT, LETORIA G | 3623 | §101§103 | Final Rejection | — | Pending | Aug 09, 2024 |
| 18793396 | METHOD FOR NUCLEAR GENOME EDITING USING PLASTID SELECTABLE MARKERS | Phykion Inc. | ORDAZ, CHRISTIAN JOSE | 1663 | §103§112 | Non-Final OA | — | Pending | Aug 02, 2024 |
| 18793315 | SEPARATING IONS IN AN ION TRAP | Micromass UK Limited | MCCORMACK, JASON L | §102§103Other | Non-Final OA | — | Pending | Aug 02, 2024 | |
| 18789272 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | Pfizer, Inc. | VAJDA, KRISTIN ANN | 1624 | DP | Non-Final OA | — | Pending | Jul 30, 2024 |
| 18833468 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. | LADD, CAROLYN LOUISE | 1629 | §112 | Non-Final OA | — | Pending | Jul 26, 2024 |
| 18833849 | NTSR1-TARGETED RADIOPHARMACEUTICALS AND DNA DAMAGE RESPONSE INHIBITOR COMBINATION THERAPY | Fusion Pharmaceuticals Inc. | MOSHER, ERIC PARKER | §103§112DP | Non-Final OA | — | Pending | Jul 26, 2024 | |
| 18833315 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. | LADD, CAROLYN LOUISE | §112 | Non-Final OA | — | Pending | Jul 25, 2024 | |
| 18833319 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. | ROZOF, TIMOTHY R | §112DP | Non-Final OA | — | Pending | Jul 25, 2024 | |
| 18783250 | MACROCYCLIC AZOLOPYRIDINE DERIVATIVES AS EED AND PRC2 MODULATORS | Fulcrum Therapeutics, Inc. | SEAMAN, D MARGARET M | §112 | Non-Final OA | — | Pending | Jul 24, 2024 | |
| 18772865 | METHOD FOR PREPARING BENZOFURAN DERIVATIVE | Shanghai Hengrui Pharmaceutical Co., Ltd. | SANDERSON, LEE E | 3991 | Other | Non-Final OA | — | Pending | Jul 15, 2024 |
| 18770318 | PHENYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF | Deciphera Pharmaceuticals, LLC | KIFLE, BRUCK | DP | Non-Final OA | — | Pending | Jul 11, 2024 | |
| 18768886 | WEARABLE DEVICE FOR TARGETED PERIPHERAL STIMULATION | Encora, Inc. | MILLER, CHRISTOPHER E | §101§103§112 | Non-Final OA | — | Pending | Jul 10, 2024 | |
| 18764647 | METHOD FOR TREATMENT OF PARKINSON'S DISEASE | Neuroderm, Ltd. | SHIAO, REI TSANG | §103§112DP | Non-Final OA | — | Pending | Jul 05, 2024 | |
| 18760242 | METHODS OF CYTOTOXIC GENE THERAPY TO TREAT TUMORS | Candel Therapeutics, Inc. | WILSON, MICHAEL C | 1638 | §102§112DP | Non-Final OA | — | Pending | Jul 01, 2024 |
| 18725665 | CD4+ T CELLS EXPRESSING IL-10 AND CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF | Tr1X, Inc. | HOLTZMAN, KATHERINE ANN | 1646 | §103§112Other | Non-Final OA | — | Pending | Jun 28, 2024 |
| 18753253 | BONE AUGMENTATION UTILIZING MUSCLE-DERIVED PROGENITOR COMPOSITIONS, AND TREATMENTS THEREOF | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | FOX, ALLISON M | §102§103§112DP | Non-Final OA | — | Pending | Jun 25, 2024 | |
| 18741564 | DEVICES AND METHODS FOR CORONARY SINUS PRESSURE RELIEF | Corvia Medical, Inc. | PRESTON, REBECCA STRASZHEIM | §103§112 | Non-Final OA | — | Pending | Jun 12, 2024 | |
| 18740064 | HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | Tango Therapeutics, Inc. | ANDERSON, REBECCA L | DP | Non-Final OA | — | Pending | Jun 11, 2024 | |
| 18717390 | SOLID STATE FORMS OF AN FGFR INHIBITOR | Khora Spv 1. LLC | FETTEROLF, BRANDON J | §102DP | Non-Final OA | — | Pending | Jun 06, 2024 | |
| 18678378 | SYSTEMS AND METHODS FOR PREDICTING CYBERSECURITY RISK BASED ON ENTITY FIRMOGRAPHICS | Bitsight Technologies, Inc. | NAHAR, SAYEDA S | 2435 | §103 | Final Rejection | — | Pending | May 30, 2024 |
| 18675900 | PREDICTION OF MEAL AND/OR EXERCISE EVENTS BASED ON PERSISTENT RESIDUALS | Insulet Corporation | SMALE, AVERY E | §102§103§112 | Non-Final OA | — | Pending | May 28, 2024 | |
| 18675875 | 4,4-DISUBSTITUTED CYCLOHEXYL BRIDGED HEPTAMETHINE CYANINE DYES AND USES THEREOF | Visen Medical, Inc. | JONES, DAMERON LEVEST | 1618 | DP | Non-Final OA | — | Pending | May 28, 2024 |
| 18675958 | CD71 BINDING FIBRONECTIN TYPE III DOMAINS | Aro Biotherapeutics | DABKOWSKI, ERINNE R | 1654 | §112 | Final Rejection | 22d | Pending | May 28, 2024 |
| 18711986 | HETEROCYCLIC SUBSTITUTED 1,3,4-THIADIAZOLE AND PYRIDAZINE COMPOUNDS AND METHODS OF USING THE SAME | Rgenta Therapeutics, Inc. | RAHMANI, NILOOFAR | §112 | Non-Final OA | — | Pending | May 21, 2024 | |
| 18711434 | TABLET FORMULATIONS OF RBP4 INHIBITORS AND METHODS OF USE | Belite Bio, Inc. | JANOSKO, CHASITY PAIGE | 1613 | §103§112 | Non-Final OA | — | Pending | May 17, 2024 |
| 18667893 | SYSTEM AND METHOD FOR PREVENTION OF DEEP-VEIN THROMBOSIS (DVT) EDEMA OR MUSCLE ATROPHY | Restorative Therapies, Inc. | SUL, DOUGLAS YOUNG | §103§112 | Non-Final OA | — | Pending | May 17, 2024 | |
| 18667441 | 1H-BENZO[B]AZEPIN-2(3H)-ONE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | Chengdu Anticancer Bioscience, Ltd. | NESTOR, DONNA MICHELLE | §103§112 | Non-Final OA | — | Pending | May 17, 2024 | |
| 18711470 | A METHOD OF CONFIGURING A STRING OF PULSES | Waters Technologies Ireland Limited | SMYTH, ANDREW P | §101 | Non-Final OA | — | Pending | May 17, 2024 | |
| 18710715 | CDK2 INHIBITORS AND METHODS OF MAKING AND USING SAME | BLUEPRINT MEDICINES CORPORATION | MARTIN, KEVIN STEPHEN | §102§103§112 | Non-Final OA | — | Pending | May 16, 2024 | |
| 18664718 | AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF | Avalyn Pharma Inc. | TRUONG, QUANGLONG N | 1615 | DP | Non-Final OA | — | Pending | May 15, 2024 |
| 18710558 | METHODS AND SYSTEMS FOR AUTOMATED SAMPLE PROCESSING | Erisyon Inc. | WRIGHT, PATRICIA KATHRYN | §102§103 | Non-Final OA | — | Pending | May 15, 2024 | |
| 18661020 | METHODS TO DEMONSTRATE PROGRESS TOWARDS FULL ADAPTATION AND TO PRESENT POTENTIAL IMPROVEMENTS THROUGH BEHAVIORAL CHANGES | Insulet Corporation | MENDEZ, MANUEL A | §103 | Non-Final OA | — | Pending | May 10, 2024 | |
| 18659379 | SYSTEM AND METHOD FOR TREATMENT OF PERIODONTIC POCKETS USING DISPOSABLE INSERTS | Convergent Dental, Inc. | MORAN, EDWARD JOHN | 3772 | §103§112Other | Non-Final OA | 16d | Pending | May 09, 2024 |
| 18708545 | METHODS AND COMPOSITIONS FOR TREATING MICROGLIAL DYSFUNCTION AND IMPROVING METABOLIC DYSFUNCTION | Albert-Ludwigs-Universität Freiburg | FAN, LYNN Y | 1759 | §103 | Non-Final OA | — | Pending | May 08, 2024 |
| 18658604 | SELF-AMPLIFYING RNA COMPOSITIONS AND METHODS OF USE THEREOF | Gritstone Bio, Inc. | CHESTNUT, BARRY A | §103§112 | Non-Final OA | — | Pending | May 08, 2024 | |
| 18708028 | METHOD FOR MANUFACTURING GATE-ALL-AROUND TFET DEVICE | Institute Of Microelectronics, Chinese Academy Of Sciences | DAS, PINAKI | §103§112 | Non-Final OA | — | Pending | May 07, 2024 | |
| 18655166 | Systems and Methods for Monitoring Operations of an Infusion Delivery Device Using a Pressure Sensor | Insulet Corporation | RITCHIE, HADEN MATTHEW | §102§103 | Non-Final OA | — | Pending | May 03, 2024 | |
| 18707117 | PRIMED UTERINE-DERIVED REGENERATIVE CELL COMPOSITIONS AND USES THEREOF | Gallant Pet, Inc. | RAHMAN, MASUDUR | §103§112 | Non-Final OA | — | Pending | May 02, 2024 | |
| 18706441 | Monoclonal Antibodies Against Carcinoembryonic Antigens, and Their Uses | Mab Biotec, Inc. | NICKOL, GARY B | 1642 | DP | Non-Final OA | — | Pending | May 01, 2024 |
| 18251079 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | AbbVie Inc. | RAO, PADMAJA S | 1627 | §102§103§112 | Non-Final OA | — | Pending | Apr 28, 2024 |
| 18648288 | METHODS AND SYSTEMS FOR ASSESSING HEMORRHOIDS AND TREATMENT EFFECTIVENESS THEREOF | Citius Pharmaceuticals, Inc. | LEE, ANDREW ELDRIDGE | 3684 | §101§102§103 | Final Rejection | — | Pending | Apr 26, 2024 |
| 18704678 | JUP BIOMARKER FOR THE DIAGNOSIS OF DISEASES OR DISORDERS OF THE FEMALE REPRODUCTIVE TRACT | UNIVERSITÄT BERN | KIM, YOUNG J | §101§102§103§112 | Non-Final OA | — | Pending | Apr 25, 2024 | |
| 18704267 | METHODS OF TREATING ABNORMAL CELL GROWTH | Verastem, Inc. | ARCORIA, PAUL JOSEPH | §103§112 | Non-Final OA | — | Pending | Apr 24, 2024 | |
| 18642140 | METHOD AND SYSTEM FOR CONSISTENT, REPEATABLE, AND SAFE CRYOSPRAY TREATMENT OF AIRWAY TISSUE | Csa Medical, Inc. | PEFFLEY, MICHAEL F | 3794 | §102§103 | Final Rejection | 36d overdue | Pending | Apr 22, 2024 |
| 18640987 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | Monte Rosa Therapeutics AG | KOSTURKO, GEORGE W | §102DP | Non-Final OA | — | Pending | Apr 19, 2024 | |
| 18637946 | STERILE DISPOSABLE INTERFACES FOR PERCUTANEOUS INSTRUMENTS | Mendaera, Inc. | WALKER, OLIVIA | 3796 | §102§103 | Final Rejection | 12d | Pending | Apr 17, 2024 |
| 18634339 | CHARGED AEROSOL DETECTORS | Waters Technologies Corporation | OLAMIT, JUSTIN N | 2853 | §102§103§112 | Final Rejection | — | Pending | Apr 12, 2024 |
| 18632667 | DOPA DECARBOXYLASE INHIBITOR COMPOSITIONS | Neuroderm, Ltd. | HUI, SAN MING R | §101DP | Non-Final OA | — | Pending | Apr 11, 2024 | |
| 18699523 | Compositions and Methods for Treating Cag Repeat Diseases | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY | RYAN, DOUGLAS CHARLES | §102§103§112 | Non-Final OA | — | Pending | Apr 08, 2024 | |
| 18698443 | ION DETECTORS | Micromass UK Limited | OSENBAUGH-STEWART, ELIZA W | 2881 | §102§103§112 | Final Rejection | — | Pending | Apr 04, 2024 |
| 18620441 | PROCESS FOR PURIFICATION OF PROTEIN | Kashiv Biosciences, LLC | HAQ, SHAFIQUL | 1678 | §103Other | Non-Final OA | 36d | Pending | Mar 28, 2024 |
| 18620649 | PROCESS FOR PURIFICATION OF PROTEIN | Kashiv Biosciences, LLC | HAQ, SHAFIQUL | 1678 | §103 | Final Rejection | — | Pending | Mar 28, 2024 |
| 18694103 | GLUCOSE MONITOR INJECTION PORT | Insulet Corporation | STIGELL, THEODORE J | §102§103 | Final Rejection | — | Pending | Mar 21, 2024 | |
| 18612960 | Bispecific Asymmetric Heterodimers Comprising Anti-CD3 Constructs | Zymeworks, Inc. | HUYNH, PHUONG N | 1641 | §102§112 | Final Rejection | 238d overdue | Pending | Mar 21, 2024 |
| 18693796 | ION SOURCE ASSEMBLY | Micromass UK Limited | EINHORN, MICA JILLIAN | 2881 | §103§112 | Final Rejection | — | Pending | Mar 20, 2024 |
| 18601141 | WIRELESS COMMUNICATION TAGS TO ENHANCE AID SYSTEM PERFORMANCE | Insulet Corporation | GARTLAND, SCOTT D | 3685 | §101§102 | Final Rejection | 14d | Pending | Mar 11, 2024 |
| 18600407 | DOSING REGIMENS FOR THE MOBILIZATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | Ensoma, Inc. | SABILA, MERCY HELLEN | §102§103DP | Non-Final OA | — | Pending | Mar 08, 2024 | |
| 18598289 | PRODUCTION OF HEPATOCYTES | Cambridge Enterprise Limited (Gb/Gb) | GU, QINHUA | 1633 | §103§112 | Non-Final OA | — | Pending | Mar 07, 2024 |
| 18593643 | INDOLE COMPOUNDS AND METHODS OF USE | Genzyme Corporation | HEASLEY, MEGHAN CHRISTINE | 1626 | §112 | Non-Final OA | — | Pending | Mar 01, 2024 |
| 18591704 | CHROMAN DERIVATIVES HAVING ESTROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | Accutar Biotechnology Inc. | KOSACK, JOSEPH R | 3991 | Other | Non-Final OA | — | Pending | Feb 29, 2024 |
| 18687692 | ISOQUINOLINONES AND QUINOLINONES AS MODULATORS OF POLRMT | Pretzel Therapeutics, Inc. | SHAMEEM, GOLAM M | 1621 | §102 | Non-Final OA | — | Pending | Feb 28, 2024 |
| 18686595 | NEBULISER OUTLET ASSEMBLY | Micromass UK Limited | WANG, JING | 2881 | §102§103 | Non-Final OA | — | Pending | Feb 26, 2024 |
| 18686737 | SYSTEMS AND METHODS FOR INTEGRATING FIRE SAFETY FEATURES WITHIN ROBOTIC FURNITURE AND INTERIOR ARCHITECTURAL ELEMENTS | Ori Inc. | CAMERON, ATTICUS A | 3658 | §103 | Final Rejection | — | Pending | Feb 26, 2024 |
| 18584998 | PEPTIDES AND PEPTIDE CONJUGATES FOR TREATING MENTAL DISORDERS | Kazusa Dna Research Institute | LEE, JIA-HAI | 1658 | §102§112DP | Non-Final OA | — | Pending | Feb 22, 2024 |
| 18685018 | JAK2 INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. | OTTON, ALICIA L | 1629 | §102§112 | Non-Final OA | — | Pending | Feb 20, 2024 |
| 18444227 | COMPOSITIONS AND METHODS FOR MAKING AND USING AN IMMORTALIZED LIBRARY | Flagship Pioneering Innovations Vi, LLC | DAUNER, JOSEPH G | 1682 | §103§112 | Final Rejection | 2d overdue | Pending | Feb 16, 2024 |
| 18683423 | METHODS AND COMPOSITIONS FOR TREATING HYPERGLYCEMIA AND DIABETES | Anagram Therapeutics, Inc. | EIX, EMILY FAY | 1653 | §101§102§103§112DP | Non-Final OA | — | Pending | Feb 13, 2024 |
| 18683078 | COMBINATION THERAPY USING VPS34 INHIBITORS | Deciphera Pharmaceuticals, LLC | PECKHAM, RICHARD GRANT | 1627 | §102§103DP | Non-Final OA | — | Pending | Feb 12, 2024 |
| 18437595 | SYSTEM AND METHOD FOR REDUCING CGM WARM-UP TIME BY APPLICATION OF OPTICAL ENERGY | Insulet Corporation | LIU, CHU CHUAN | 3791 | §103 | Final Rejection | 30d | Pending | Feb 09, 2024 |
| 18437804 | MEDICAL DEVICE | Arsenal Medical, Inc. | GABR, MOHAMED GAMIL | 3771 | §102 | Non-Final OA | — | Pending | Feb 09, 2024 |
| 18681014 | ANALYTIC METHOD AND DEVICE FOR QUANTITATIVELY CALCULATING LINE EDGE ROUGHNESS IN PLASMA ULTRA-DIFFRACTION PHOTOETCHING PROCESS | Institute Of Microelectronics, Chinese Academy Of Sciences | WHITESELL, STEVEN H | 1759 | §102§112 | Final Rejection | — | Pending | Feb 02, 2024 |
| 18294893 | PHRENIC NERVE PACING DEVICE | Texas Heart Institute | SAHAND, SANA | 3796 | §103 | Final Rejection | — | Pending | Feb 02, 2024 |
| 18429539 | SYSTEMS AND METHODS FOR INFERRING ENTITY RELATIONSHIPS VIA NETWORK COMMUNICATIONS OF USERS OR USER DEVICES | Bitsight Technologies, Inc. | RANDHAWA, MANDISH K | 2477 | DP | Final Rejection | 71d overdue | Pending | Feb 01, 2024 |
| 18294510 | A PHARMACEUTICAL COMBINATION AND USE THEREOF | Ascentage Pharma Group Corp Limited | OH, TAYLOR V | 1625 | §102§112 | Non-Final OA | — | Pending | Feb 01, 2024 |
| 18425439 | MULTI-MATERIAL FIBERS AND METHODS OF MANUFACTURING THE SAME | Massachusetts Institute Of Technology | LEE, SEUNG H | 2876 | §102 | Non-Final OA | 9d overdue | Pending | Jan 29, 2024 |
| 18421551 | DERIVATIZED CHITOSAN POLYMERS AND METHODS OF TREATING VASCULAR DISORDERS | Synedgen, Inc. | LAU, JONATHAN S | 1693 | §103DP | Non-Final OA | 60d overdue | Pending | Jan 24, 2024 |
| 18416440 | DEVICES AND METHODS FOR TREATING HEART FAILURE | Corvia Medical, Inc. | YANG, CHENG FONG | 3781 | §103 | Final Rejection | — | Pending | Jan 18, 2024 |
| 18404740 | CHROMAN DERIVATIVES HAVING ESTROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | Accutar Biotechnology Inc. | SANDERSON, LEE E | 3991 | DP | Non-Final OA | — | Pending | Jan 04, 2024 |
| 18396017 | PURINONE DERIVATIVE HYDROCHLORIDE | Ono Pharmaceutical Co., Ltd. | KOSAR, ANDREW D | 1625 | §101§112DP | Non-Final OA | — | Pending | Dec 26, 2023 |
| 18390450 | CONTAINMENT, ACTIVATION, DEPLOYMENT, AND INTEGRATED FUNCTIONS OF FLEXIBLE, SLENDER ELEMENTS | Insulet Corporation | SMALE, AVERY E | 3783 | §102§103 | Final Rejection | — | Pending | Dec 20, 2023 |
| 18389888 | METHODS OF TREATING GASTROINTESTINAL STROMAL TUMORS | Deciphera Pharmaceuticals, LLC | SZNAIDMAN, MARCOS L | 1628 | §103 | Non-Final OA | — | Pending | Dec 20, 2023 |
| 18571091 | ANTIBODIES WHICH BIND HUMAN FIBRIN OR FIBRINOGEN yC DOMAIN AND METHODS OF USE | Therini Bio, Inc. | DARPOLOR, JOSEPHINE KEBBEH | §102§103§112DP | Non-Final OA | — | Pending | Dec 15, 2023 | |
| 18571170 | SYSTEMS AND METHODS FOR INTERRUPTING NERVE ACTIVITY TO TREAT A MEDICAL CONDITION | Texas Medical Center | FLANAGAN, BEVERLY MEINDL | 3794 | §102 | Final Rejection | 33d | Pending | Dec 15, 2023 |
| 18541618 | COMBINATION COMPRISING A NEUROTENSIN RECEPTOR BINDING COMPOUND AND NAPOX | Fusion Pharmaceuticals Inc. | DICKINSON, PAUL W | §101§103DP | Non-Final OA | — | Pending | Dec 15, 2023 | |
| 18541584 | COMBINATION COMPRISING A NEUROTENSIN RECEPTOR BINDING COMPOUND AND FOLFIRINOX | Fusion Pharmaceuticals Inc. | BAEK, JONGHWAN NMN | 1618 | §103Other | Non-Final OA | — | Pending | Dec 15, 2023 |
| 18570579 | Self-Assembling Nanoparticles Based On Amphiphilic Peptides for Drug Delivery Applications | The United States Department of Health and Human Services | DAVIS, BRIAN J | 1614 | §102§112 | Non-Final OA | — | Pending | Dec 14, 2023 |
| 18535441 | METHOD, SYSTEM, AND APPARATUS FOR ANALYZING AN ANALYTE OF A SINGLE CELL | Mission Bio, Inc. | SALMON, KATHERINE D | 1682 | §102§103§112DP | Non-Final OA | — | Pending | Dec 11, 2023 |
| 18569180 | METHOD FOR PREPARING AN [18F] RADIOLABELLED COMPOUND WITH LOW WATER CONTENT DURING LABELLING STEP | GE Healthcare Limited | SCHLIENTZ, LEAH H | 1618 | §102§103§112 | Non-Final OA | — | Pending | Dec 11, 2023 |
| 18569113 | TREATMENT OF DKK2 RELATED DISEASES AND DISORDERS | Empirico Inc. | VANHORN, ABIGAIL LOUISE | §102§103§112 | Non-Final OA | — | Pending | Dec 11, 2023 | |
| 18535291 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | Sagimet Biosciences Inc. | BORALSKY, LUKE ALAN | 1624 | §103DP | Non-Final OA | — | Pending | Dec 11, 2023 |
| 18568440 | SUBCUTANEOUS FORMULATION AND METHODS FOR TREATING EDEMA REFRACTORY TO ORAL DIURETICS | Resq Pharmaceuticals LLC | SAEED, ALI S | 1616 | §103DP | Non-Final OA | — | Pending | Dec 08, 2023 |
| 18568694 | NON-NANOPARTICULATE APPLICATION FORMS OF MACROLIDES | Nucleus Medical GmbH | MERCIER, MELISSA S | 1615 | §102§103§112 | Final Rejection | 14d | Pending | Dec 08, 2023 |
| 18568165 | VACUUM SYSTEM FOR A MASS SPECTROMETER | Micromass UK Limited | WANG, JING | 2881 | §103 | Non-Final OA | 38d overdue | Pending | Dec 07, 2023 |
| 18532424 | Papain-like protease (PLpro) inhibitors | Pfizer, Inc. | BELL, SARA ELIZABETH | 1625 | §102§112 | Non-Final OA | — | Pending | Dec 07, 2023 |
| 18567011 | TREATMENT OF ANGPTL4 RELATED DISEASES | Empirico Inc. | ARIETI, RUTH SOPHIA | 1635 | §102§103§112Other | Non-Final OA | — | Pending | Dec 04, 2023 |
| 18565630 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | Captor Therapeutics S.A. | MOORE, SUSANNA | 1624 | §103§112 | Non-Final OA | — | Pending | Nov 30, 2023 |
| 18523044 | LEAD SCREW WITHIN RESERVOIR | Insulet Corporation | ZAMORY, JUSTIN L | 3783 | §102§112 | Non-Final OA | — | Pending | Nov 29, 2023 |
| 18519589 | SOLID PHASE NEGATIVE ENRICHMENT | Harbinger Health, Inc. | HASAN, KHALEDA B | §103§112DP | Non-Final OA | — | Pending | Nov 27, 2023 | |
| 18514724 | CUTTING SUBASSEMBLY AND CONDITIONING ASSEMBLY FOR AN ENVIRONMENT | Rapid Micro Biosystems, Inc. | BOWERS, NATHAN ANDREW | 1799 | §102§103§112 | Final Rejection | 69d | Pending | Nov 20, 2023 |
| 18562768 | BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION | BELITE BIO, LLC | RAHMANI, NILOOFAR | 1691 | §102§112 | Non-Final OA | 30d overdue | Pending | Nov 20, 2023 |
| 18508634 | SOLAR THERMAL AEROGEL RECEIVER AND MATERIALS THEREFOR | Massachusetts Institute Of Technology | BASICHAS, ALFRED | 3762 | §103 | Non-Final OA | 57d | Pending | Nov 14, 2023 |
| 18508933 | PRESSED AND MIXED THIN FILM ENZYMATIC REACTOR AND METHODS OF MAKING THE SAME | Waters Technologies Corporation | JONES-FOSTER, ERICA NICOLE | 1656 | §103§112 | Final Rejection | 22d | Pending | Nov 14, 2023 |
| 18504790 | METHODS AND SYSTEMS FOR NON-BLOCKING TRANSACTIONS | Cockroach Labs, Inc. | FILIPCZYK, MARCIN R | 2153 | §102Other | Non-Final OA | 367d overdue | Pending | Nov 08, 2023 |
| 18504497 | REDUCING JUNCTION EPITOPE PRESENTATION FOR NEOANTIGENS | Gritstone Bio, Inc. | GODDARD, LAURA B | 1642 | §101§103§112DP | Non-Final OA | — | Pending | Nov 08, 2023 |
| 18503723 | Microfluidic Devices for High Throughput Screening of Cell-Cell Interactions | Shennon Biotechnologies Inc. | CORDAS, EMILY ANN | 1632 | §102§103§112DP | Non-Final OA | — | Pending | Nov 07, 2023 |
| 18386647 | PROGRAMMATIC MEDICAMENT TITRATION WITH A MEDICAMENT DELIVERY DEVICE | Insulet Corporation | SWANSON, LEAH JENNINGS | 3783 | §103 | Final Rejection | 14d | Pending | Nov 03, 2023 |
| 18386502 | RECOMBINANT ALGAE HAVING HIGH BIOMASS AND LIPID PRODUCTIVITY | Phykion Inc. | JONES-FOSTER, ERICA NICOLE | 1656 | §112 | Final Rejection | 53d | Pending | Nov 02, 2023 |
| 18499346 | CHEMICAL MONITORING UNIT AND METHODS | General Galactic Systems, Inc. | MERCADO, ALEXANDER A | 2855 | §103§112 | Final Rejection | 34d | Pending | Nov 01, 2023 |
| 18498275 | USE OF NON-INVASIVE GLUCOSE SENSORS AND GLUCOSE RATE OF CHANGE DATA IN AN INSULIN DELIVERY SYSTEM | Insulet Corporation | GOLLAMUDI, NEERAJA | 3783 | §102§103§112 | Non-Final OA | — | Pending | Oct 31, 2023 |
| 18385649 | BODILY FLUID TARGET ENRICHMENT | Harbinger Health, Inc. | HASAN, KHALEDA B | 1636 | §103§112DP | Non-Final OA | — | Pending | Oct 31, 2023 |
| 18558139 | PYRIDINO-OR PYRIMIDO-CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Zhejiang Genfleet Therapeutics Co., Ltd. | SHTERENGARTS, SAMANTHA L | 1623 | §102§112 | Non-Final OA | — | Pending | Oct 30, 2023 |
| 18557528 | ANALYTICAL HPLC | GE Healthcare Limited | BRAZIN, JACQUELINE | 1798 | §102§103 | Non-Final OA | — | Pending | Oct 26, 2023 |
| 18494491 | Self-Assembling Nanoparticles | The United States Of America, AS Represented By The Secretary, Department Of Health | VARADARAJ, ARCHANA | 1675 | §112DP | Non-Final OA | — | Pending | Oct 25, 2023 |
| 18494545 | TREATMENT OF OCULAR DISEASES USING ENDOTHELIN RECEPTOR ANTAGONISTS | Perfuse Therapeutics, Inc. | HUANG, GIGI GEORGIANA | 1613 | §102§103DPOther | Non-Final OA | 70d | Pending | Oct 25, 2023 |
| 18490413 | COMPACT RATCHET MECHANISM | Insulet Corporation | KASHYAP, ESHA PRAKASH | 3783 | §102§103 | Non-Final OA | — | Pending | Oct 19, 2023 |
| 18486830 | MULTI-LEVEL INVERTER FOR WIRELESS POWER TRANSMISSION | Witricity Corporation | FINCH III, FRED E | §102§103§112 | Non-Final OA | — | Pending | Oct 13, 2023 | |
| 18379912 | NON-VIRAL HOMOLOGY MEDIATED END JOINING | Arsenal Biosciences, Inc. | YU, DELPHINUS DOU YI | 1636 | §103 | Non-Final OA | — | Pending | Oct 13, 2023 |
| 18555277 | POMACE LEACHATE HERBICIDE COMPOSITION AND METHODS | Jackson Family Wines, Inc. | PEEBLES, KATHERINE | 1617 | §101§102§103 | Final Rejection | 4d overdue | Pending | Oct 13, 2023 |
| 18286966 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | Hotspot Therapeutics, Inc. | SEITZ, ANTHONY JOSEPH | 1629 | Other | Non-Final OA | — | Pending | Oct 13, 2023 |
| 18485766 | ISOINDOLINONE COMPOUNDS | Monte Rosa Therapeutics AG | BARSKY, JARED | 1628 | §112DP | Non-Final OA | — | Pending | Oct 12, 2023 |
| 18480274 | ROBOTIC SYSTEM FOR DELIVERING ENERGY TO AN ANATOMICAL ELEMENT | Csa Medical, Inc. | LANCASTER, LINDSAY REGAN | 3794 | §103 | Non-Final OA | — | Pending | Oct 03, 2023 |
| 18553352 | POLYMORPHIC FORMS OF (S)-12-FLUORO-4-(1-METHYL-1H-PYRAZOL-5-YL)-7A,8,13,14-TETRAHYDRO-7H-[1,2,4]TRIAZOLO[4',3':1,6]PYRIDO[3,2-B]BENZOFURO[4,3-FG][1,4]OXAZONINE | Fulcrum Therapeutics, Inc. | HAVLIN, ROBERT H | 1626 | §102§103Other | Final Rejection | 71d overdue | Pending | Sep 29, 2023 |
| 18553317 | MACROCYCLIC AZOLOPYRIDINES | Fulcrum Therapeutics, Inc. | KENYON, JOHN S | 1625 | §103§112 | Non-Final OA | — | Pending | Sep 29, 2023 |
| 18477504 | HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF | University of Basel | PERREIRA, MELISSA JEAN | 1618 | §103 | Final Rejection | 30d overdue | Pending | Sep 28, 2023 |
| 18474060 | COMPOSITIONS AND METHODS FOR MAKING AND USING AN IMMORTALIZED LIBRARY | Flagship Pioneering Innovations Vi, LLC | DAUNER, JOSEPH G | 1682 | §103§112DPOther | Non-Final OA | 70d | Pending | Sep 25, 2023 |
| 18474211 | SOLID TARGET SYSTEMS FOR THE PRODUCTION OF HIGH-PURITY RADIONUCLIDE COMPOSITIONS | Nuclidium AG | CRAIG, KAILA ANGELIQUE | 1618 | §103 | Final Rejection | — | Pending | Sep 25, 2023 |
| 18471563 | PHARMACEUTICAL COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF A DISEASE OR DISORDER CAUSED BY OR ASSOCIATED WITH ONE OR MORE PREMATURE TERMINATION CODONS | Monte Rosa Therapeutics AG | HASTINGS, ALISON AZAR | 1627 | §103 | Final Rejection | 6d | Pending | Sep 21, 2023 |
| 18551143 | GENE THERAPIES FOR 21-HYDROXYLASE DEFICIENCY | Adrenas Therapeutics, Inc. | AMICK, THOMAS RUSSE | 1638 | §102§112Other | Non-Final OA | 49d | Pending | Sep 18, 2023 |
| 18550920 | NOVEL FORMULATION OF FUSION PROTEIN | Kashiv Biosciences, LLC | CHANDRA, GYAN | 1674 | §103§112 | Non-Final OA | — | Pending | Sep 15, 2023 |
| 18368931 | METHODS, SYSTEMS, AND ARRAYS FOR BIOMOLECULAR ANALYSIS | Vibrant Holdings, LLC | BROWN, MINDY G | 1634 | §112DP | Final Rejection | — | Pending | Sep 15, 2023 |
| 18282254 | PYRIMIDINE-FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Zhejiang Genfleet Therapeutics Co., Ltd. | HEASLEY, MEGHAN CHRISTINE | 1626 | §102 | Non-Final OA | 56d | Pending | Sep 15, 2023 |
| 18468355 | MULTI-LAYERED BIOMIMETIC OSTEOCHONDRAL IMPLANTS AND METHODS OF USING THEREOF | Hyalex Orthopaedics, Inc. | HOBAN, MELISSA A | §102§103§112 | Non-Final OA | — | Pending | Sep 15, 2023 | |
| 18466217 | MECHANISM PROVIDING VARIABLE FILL CAPABILITY FOR A LIQUID RESERVOIR AND PUMP | Insulet Corporation | LAZO, THOMAS E | 3745 | §102§112 | Non-Final OA | — | Pending | Sep 13, 2023 |
| 18466639 | SYSTEMS AND METHODS FOR USING MICROBIAL MEASUREMENTS TO DERIVE FINANCIAL PRODUCTS | Ancera Inc. | KALLAL, ROBERT JAMES | §101§103§112 | Non-Final OA | — | Pending | Sep 13, 2023 | |
| 18464519 | METHODS OF TREATING GASTROINTESTINAL STROMAL TUMORS | Deciphera Pharmaceuticals, LLC | VALENROD, YEVGENY | 1628 | §103 | Final Rejection | 24d overdue | Pending | Sep 11, 2023 |
| 18281388 | SYNTHETIC PRE-PROTEIN SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN BACILLUS BACTERIA | Tenza, Inc. | GROOMS, TIFFANY NICOLE | 1658 | §112 | Non-Final OA | — | Pending | Sep 11, 2023 |
| 18464035 | MULTIPLE-TIERED SCREENING AND SECOND ANALYSIS | Flagship Pioneering Innovations Vi, LLC | LIN, JERRY | 1671 | §101§103§112DP | Non-Final OA | — | Pending | Sep 08, 2023 |
| 18027275 | ELECTROCHEMICAL SYSTEMS AND METHODS | Massachusetts Institute Of Technology | RUFO, LOUIS J | 1759 | §112 | Non-Final OA | — | Pending | Sep 08, 2023 |
| 18463880 | COMPUTING ARCHITECTURE FOR TRANSACTION AUTHORIZATION AND MEDIUMS AND METHODS FOR THE SAME | Perpay Inc. | JUNG, HENRY H | 3695 | §101§102§103 | Final Rejection | — | Pending | Sep 08, 2023 |
| 18463183 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | AbbVie Inc. | O DELL, DAVID K | 1621 | §103DP | Non-Final OA | — | Pending | Sep 07, 2023 |
| 18549452 | STABILIZED LIQUID COMPOSITIONS COMPRISING A LEVODOPA-TYROSINE CONJUGATE AND USES THEREOF | Neuroderm, Ltd. | CHO, DAVID H | 1693 | §102§103§112Other | Non-Final OA | 22d | Pending | Sep 07, 2023 |
| 18462918 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | AbbVie Inc. | NOLAN, JASON MICHAEL | 1623 | Other | Final Rejection | 118d overdue | Pending | Sep 07, 2023 |
| 18461179 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | MCDOWELL, BRIAN E | 1624 | — | Non-Final OA | 71d overdue | Pending | Sep 05, 2023 |
| 18279938 | ENHANCED TARGETING USING ANTIBODY-OLIGONUCLEOTIDE CONJUGATES | UNIVERSITY OF MARYLAND, BALTIMORE | NICKOL, GARY B | 1643 | §112 | Final Rejection | 7d | Pending | Sep 01, 2023 |
| 18240823 | DEVICES FOR COLLECTING CAPILLARY BLOOD AND METHODS FOR SAME | Paulus Holdings Limited | PORTILLO, JAIRO H | 3791 | §103DP | Final Rejection | 45d overdue | Pending | Aug 31, 2023 |
| 18457825 | METHODS OF TREATING DISORDERS WITH ULK INHIBITORS | Deciphera Pharmaceuticals, LLC | KUCKLA, ANNA GRACE | 1626 | §103 | Final Rejection | 42d | Pending | Aug 29, 2023 |
| 18547207 | REVERSIBLE TERMINATORS | Ansa Biotechnologies, Inc. | RILEY, JEZIA | 1681 | §102§112 | Non-Final OA | — | Pending | Aug 21, 2023 |
| 18451530 | USE OF LOGARITHMIC TRANSFORM/FILTER TO IMPROVE OPERATION OF MEDICAMENT DELIVERY DEVICE | Insulet Corporation | NEWTON, CHAD A | 3681 | §102 | Non-Final OA | — | Pending | Aug 17, 2023 |
| 18546528 | ION SOURCE NEBULISER | Micromass UK Limited | KALISZEWSKI, ALINA ROSE | 2881 | §101§103 | Non-Final OA | — | Pending | Aug 15, 2023 |
| 18450238 | SAFETY AND ACCURACY MEASURES FOR MEDICAMENT BOLUS DELIVERY | Insulet Corporation | PATEL, SHEFALI DILIP | 3783 | §102§103§112 | Final Rejection | — | Pending | Aug 15, 2023 |
| 18450081 | ADHESIVE LAYER WITH MULTIPLE STRENGTHS OF ADHESIVES FOR SECURING AN ON-BODY MEDICAL DEVICE TO A USER | Insulet Corporation | STIMPERT, PHILIP EARL | 3783 | §102§103 | Final Rejection | — | Pending | Aug 15, 2023 |
| 18277220 | Self-Assembling Nanoparticles Based On Amphiphilic Peptides | The United States Department of Health and Human Services | VARADARAJ, ARCHANA | 1658 | §103§112DP | Non-Final OA | — | Pending | Aug 14, 2023 |
| 18546312 | PYRROLO[3,2-D]PYRIMIDINE COMPOUNDS AND METHODS OF USE IN THE TREATMENT OF CANCER | Tango Therapeutics, Inc. | NOLAN, JASON MICHAEL | 1623 | §112 | Non-Final OA | 43d overdue | Pending | Aug 14, 2023 |
| 18448385 | APPARATUS AND METHOD FOR REDUCTION OF NEUROLOGICAL MOVEMENT DISORDER SYMPTOMS USING WEARABLE DEVICE | Encora, Inc. | RAUBENSTRAW, TYLER ALLEN | 3785 | §103Other | Final Rejection | 27d | Pending | Aug 11, 2023 |
| 18447656 | SYSTEM AND METHOD FOR APPLYING VIBRATORY STIMULUS IN A WEARABLE DEVICE | Encora, Inc. | MILLER, CHRISTOPHER E | 3785 | §102§103§112 | Final Rejection | — | Pending | Aug 10, 2023 |
| 18546010 | POWER SUPPLY SYSTEMS AND METHODS | Micromass UK Limited | GASSEN, CHRISTOPHER J | 2881 | §102§103 | Non-Final OA | 43d | Pending | Aug 10, 2023 |
| 18276527 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | Elevatebio Technologies, Inc. | COLEMAN, BRENDA LIBBY | 1624 | §102§112 | Final Rejection | 40d | Pending | Aug 09, 2023 |
| 18264217 | A METHOD OF ANALYSIS OF MASS SPECTROMETRY DATA | Waters Technologies Ireland Limited | NGHIEM, MICHAEL P | 2857 | §101§103§112 | Non-Final OA | — | Pending | Aug 03, 2023 |
| 18263820 | COMBINATION THERAPY FOR TREATING ABNORMAL CELL GROWTH | Verastem, Inc. | SEITZ, ANTHONY JOSEPH | 1629 | §102§103 | Non-Final OA | — | Pending | Aug 01, 2023 |
| 18228870 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS ASSOCIATED WITH BILE ACIDS | Novome Biotechnologies, Inc. | JACKSON-TONGUE, LAKIA J | 1645 | §102§112 | Non-Final OA | — | Pending | Aug 01, 2023 |
| 18275199 | SYSTEMS AND METHODS FOR MEASURING CELL SIGNALING PROTEIN ACTIVITY | Octant, Inc. | PAK, MICHAEL D | 1644 | §101§102§112Other | Non-Final OA | — | Pending | Jul 31, 2023 |
| 18362449 | DEVICES AND METHODS FOR PUNCTURING A CAPSULE TO RELEASE A POWDERED MEDICAMENT THEREFROM | Civitas Therapeutics, Inc. | PHILIPS, BRADLEY H | 3799 | §103§112 | Non-Final OA | 16d overdue | Pending | Jul 31, 2023 |
| 18263217 | MULTABODY CONSTRUCTS, COMPOSITIONS, AND METHODS | The Hospital for Sick Children | XIAO, YAN | 1642 | §102§103§112DP | Non-Final OA | — | Pending | Jul 27, 2023 |
| 18359183 | SYSTEMS AND METHODS FOR ASSESSING CYBERSECURITY EFFICACY OF ENTITIES AGAINST COMMON CONTROL AND MATURITY FRAMEWORKS USING EXTERNALLY-OBSERVED DATASETS | Bitsight Technologies, Inc. | HAJIABBASI, AMIR MAHDI | 2407 | §103 | Non-Final OA | — | Pending | Jul 26, 2023 |
| 18356925 | TISSUE PENETRATING AND BIODEGRADABLE DRUG DELIVERY DEVICES AND METHODS OF USE THEREOF | Panther Therapeutics, Inc. | GOTFREDSON, GAREN | 1619 | §102§103§112Other | Final Rejection | — | Pending | Jul 21, 2023 |
| 18262318 | METHOD FOR SIZE BASED EVALUATION OF PANCREATIC PROTEIN MIXTURE | Kashiv Biosciences, LLC | ROBINSON, HOPE A | 1652 | §102§103§112 | Final Rejection | 24d overdue | Pending | Jul 20, 2023 |
| 18355913 | HIGH MOLYBDENUM DUPLEX STAINLESS STEEL | Carpenter Technology Corporation | HILL, STEPHANI A | 1735 | §103 | Final Rejection | — | Pending | Jul 20, 2023 |
| 18272087 | HOMOLOGOUS ADENOVIRAL VACCINATION | Gritstone Bio, Inc. | GRIZER, CASSANDRA SENN | 1672 | §103§112 | Non-Final OA | — | Pending | Jul 12, 2023 |
| 18342951 | SYSTEM AND METHOD FOR DETECTING OCCLUSIONS IN A FLUID PATH | Insulet Corporation | BOSWORTH, KAMI A | 3783 | §102§103§112 | Final Rejection | 7d | Pending | Jun 28, 2023 |
| 18340339 | WEARABLE DRUG DELIVERY DEVICE WITH INCORPORATED FILTRATION | Insulet Corporation | ZAMORY, JUSTIN L | 3783 | §102§103 | Non-Final OA | — | Pending | Jun 23, 2023 |
| 18269301 | METHODS OF TREATING MULTIPLE SCLEROSIS | Ascentage Pharma Group Corp Limited | SHIM, DAVID M. | 1626 | §103 | Final Rejection | 51d overdue | Pending | Jun 23, 2023 |
| 18258399 | METHOD OF CONTROLLING A JOINT OF AN ORTHOPAEDIC TECHNOLOGY DEVICE AND JOINT OF THIS KIND | Ottobock SE & Co. Kgaa | NERENBERG, RENEE FLORENCIA | 3774 | §102§103 | Final Rejection | 43d overdue | Pending | Jun 20, 2023 |
| 18337683 | METHODS AND SYSTEMS FOR OPTICAL-BASED FLUID CONTROL IN A FLUID DELIVERY SYSTEM | Insulet Corporation | VOKES, KATHLEEN PAIGE | 3783 | §103 | Final Rejection | — | Pending | Jun 20, 2023 |
| 18335911 | PUSH-IN SUTURE ANCHOR SYSTEM | Responsive Arthroscopy, Inc. | SHI, KATHERINE MENGLIN | 3771 | §103§112 | Non-Final OA | 19d | Pending | Jun 15, 2023 |
| 18335103 | ALL-SUTURE ANCHOR | Responsive Arthroscopy, Inc. | HOLWERDA, KATHLEEN SONNETT | 3771 | §102§103§112 | Non-Final OA | 45d overdue | Pending | Jun 14, 2023 |
| 18257045 | FROZEN PLANT-BASED PORTIONED MILK CONCENTRATE AND METHODS OF PREPARATION THEREOF | Daily Harvest, Inc. | AXTELL, ASHLEY | 1792 | §103§112 | Non-Final OA | 42d | Pending | Jun 12, 2023 |
| 18255539 | COMPOSITIONS AND METHODS OF USE THEREOF | Gritstone Bio, Inc. | JADHAO, SAMADHAN JAISING | 1672 | §102§103§112DP | Non-Final OA | — | Pending | Jun 01, 2023 |
| 18203919 | Controllable Transcription | Cambridge Enterprise Limited (Gb/Gb) | KONOPKA, CATHERINE ANNE | 1635 | §103§112Other | Non-Final OA | — | Pending | May 31, 2023 |
| 18323538 | ASSESSMENT OF PAST INSULIN DELIVERY OUTCOMES TO AUTOMATICALLY TUNE MDA SYSTEMS | Insulet Corporation | BARTLEY, KENNETH | 3783 | §101§103 | Non-Final OA | — | Pending | May 25, 2023 |
| 18037959 | TREATMENT OF SOS2 RELATED DISEASES AND DISORDERS | Empirico Inc. | YU, DAVID TUYANG | 1635 | §102§103§112DP | Non-Final OA | — | Pending | May 19, 2023 |
| 18037960 | GALNAC COMPOSITIONS FOR IMPROVING SIRNA BIOAVAILABILITY | Empirico Inc. | VANHORN, ABIGAIL LOUISE | 1636 | §103§112 | Non-Final OA | — | Pending | May 19, 2023 |
| 18199638 | SWITCHING AND CUSTOMIZATION OF GLUCOSE PREDICTION MODELS IN MEDICAMENT DELIVERY DEVICES | Insulet Corporation | SHAH, NILAY J | 3783 | §112 | Final Rejection | — | Pending | May 19, 2023 |
| 18199476 | CUSTOMIZATION OF A GLUCOSE PREDICTION MODEL FOR A USER IN AN AUTOMATED INSULIN DELIVERY (AID) DEVICE | Insulet Corporation | LANGE, ERIC A | 3783 | §102§103§112 | Non-Final OA | 13d | Pending | May 19, 2023 |
| 18037515 | FLUMAZENIL FORMULATIONS FOR SUBCUTANEOUS INJECTION AND METHODS OF TREATMENT USING GABA RECEPTOR MODULATORS | BEXSON BIOMEDICAL, INC. | VISHNYAKOVA, ELENA VLADIMIROVNA | 1691 | §102DPOther | Non-Final OA | — | Pending | May 17, 2023 |
| 18037063 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INTESTINAL CANCER | UNITED KINGDOM RESEARCH AND INNOVATION | OUSPENSKI, ILIA I | 1644 | §102§103§112DP | Non-Final OA | — | Pending | May 15, 2023 |
| 18316851 | SYSTEMS AND METHODS FOR TRANSACTION COMMIT AND LOCK RELEASE ATOP PARTITIONED CONSENSUS | Cockroach Labs, Inc. | ADAMS, CHARLES D | 2152 | §103 | Non-Final OA | 84d | Pending | May 12, 2023 |
| 18313767 | INSTRUMENT FOR A MEDICAMENT DELIVERY DEVICE THAT ACTS AS NEEDLE AND CANNULA | Insulet Corporation | MEDWAY, SCOTT J | 3783 | §102§103§112 | Non-Final OA | 86d | Pending | May 08, 2023 |
| 18143848 | SYSTEM AND METHOD FOR LASER BASED ENDODONTIC TREATMENT | Convergent Dental, Inc. | HOLTZCLAW, MICHAEL T. | 3796 | §103 | Final Rejection | 23d | Pending | May 05, 2023 |
| 18308481 | COMPOSITIONS AND METHODS OF GENOMIC MODIFICATION OF CELLS AND USES THEREOF | Arsenal Biosciences, Inc. | YU, DAVID TUYANG | 1635 | §102§103§112 | Non-Final OA | — | Pending | Apr 27, 2023 |
| 18033470 | METHODS FOR PROCESSING FETAL SUPPORT TISSUE | BIOTISSUE HOLDINGS INC. | PAULUS, ERIN VIRGINIA | 1631 | §103 | Final Rejection | 27d | Pending | Apr 24, 2023 |
| 18306041 | COMPRESSION DETECTION AND COMPENSATION FOR A BIOLOGICAL SENSOR SECURED TO A USER | Insulet Corporation | GONZALEZ, LEI NMN | 3783 | §102§103 | Final Rejection | 58d overdue | Pending | Apr 24, 2023 |
| 18305755 | APPARATUS FOR CONTROLLED ENVIRONMENT ESTABLISHMENT, MAINTENANCE, AND SAMPLING | BIOCONSORTIA, INC. | CARREON, ADRIAN JOHN | 1799 | §103 | Non-Final OA | — | Pending | Apr 24, 2023 |
| 18250347 | RECOMBINANT T-CELL RECEPTORS THAT BIND THE NY-ESO-1 AND/OR LAGE-1A CANCER ANTIGENS | T-Cure Bioscience, Inc. | BRISTOL, LYNN ANNE | 1643 | §112Other | Final Rejection | 28d | Pending | Apr 24, 2023 |
| 18302925 | SYSTEMS AND METHODS FOR EXTERNAL DETECTION OF MISCONFIGURED SYSTEMS | Bitsight Technologies, Inc. | KORSAK, OLEG | 2492 | DP | Non-Final OA | 17d overdue | Pending | Apr 19, 2023 |
| 18131634 | SOLID PHASE NEGATIVE ENRICHMENT | Harbinger Health, Inc. | HASAN, KHALEDA B | 1636 | §103DP | Non-Final OA | — | Pending | Apr 06, 2023 |
| 18028992 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOPOIETIN LIKE 7 (ANGPTL7) RELATED DISEASES | Empirico Inc. | WHITEMAN, BRIAN A | 1636 | DP | Final Rejection | 30d | Pending | Mar 28, 2023 |
| 18190572 | AUTONOMOUS ADAPTIVITY AND SET POINT CONTROL FOR A DRUG DELIVERY DEVICE | Insulet Corporation | THOMAN, EVELYN ANNE | 3783 | §103§112 | Non-Final OA | — | Pending | Mar 27, 2023 |
| 18246783 | METHOD FOR CONTROLLING A PROSTHETIC FOOT | Otto Bock Healthcare Products GmbH | BAHENA, CHRISTIE L. | 3774 | §103 | Final Rejection | 28d overdue | Pending | Mar 27, 2023 |
| 18187792 | PROGRAMMATIC PROCESSING OF PROTEIN OR NUCLEIC ACID SEQUENCES TO IDENTIFY MUTATIONS AT PROGRAMMATICALLY DETERMINED SUBSEQUENCES | Waters Technologies Ireland Limited | SMITH, JENNIFER JOY | §101§102§103§112 | Non-Final OA | — | Pending | Mar 22, 2023 | |
| 18027346 | Compositions and Methods of Manufacturing Amphiphilic Block Copolymers that Form Nanoparticles in Situ | Institute Of Macromolecular Chemistry | ZHANG SPIERING, DONGXIU | 1616 | §103§112 | Final Rejection | 26d | Pending | Mar 20, 2023 |
| 18121328 | BODILY FLUID TARGET ENRICHMENT | Harbinger Health, Inc. | HASAN, KHALEDA B | 1636 | §103§112DP | Non-Final OA | — | Pending | Mar 14, 2023 |
| 18181386 | CONTROL ELEMENTS FOR TRACKING AND MOVEMENT OF FURNITURE AND INTERIOR ARCHITECTURAL ELEMENTS | Ori Inc. | SHAFAYET, MOHAMMED | 2116 | §103 | Non-Final OA | — | Pending | Mar 09, 2023 |
| 18177284 | CHARACTERIZING FUNCTIONAL REGULATORY ELEMENTS USING MACHINE LEARNING | Camp4 Therapeutics Corporation | BAILEY, STEVEN WILLIAM | §101§103§112 | Non-Final OA | — | Pending | Mar 02, 2023 | |
| 18176969 | SINGLE PACKAGE AUTOMATED DRUG DELIVERY SYSTEM | Insulet Corporation | WHITROCK, ZACHARIAH KIRBY | 3783 | §103 | Final Rejection | 36d | Pending | Mar 01, 2023 |
| 18024149 | Biomarkers for Predicting Multiple Sclerosis Disease Progression | Octave Bioscience, Inc. | BOWERS, ERIN M | 1653 | §101§103§112DP | Non-Final OA | — | Pending | Mar 01, 2023 |
| 18173049 | INTRA-INDIVIDUAL ANALYSIS FOR PRESENCE OF HEALTH CONDITIONS | Flagship Pioneering Innovations Vi, LLC | TURPIN, ZACHARY MARK | 1682 | §101DP | Final Rejection | — | Pending | Feb 22, 2023 |
| 18171930 | NEBULIZER DEVICE OPTIMIZATION FOR IMPROVED AEROSOL PARAMETERS AND USES THEREOF | Avalyn Pharma Inc. | PINDERSKI, JACQUELINE M | 3785 | §103 | Final Rejection | 96d overdue | Pending | Feb 21, 2023 |
| 18042375 | NEBULIZER DEVICE OPTIMIZATION FOR IMPROVED AEROSOL PARAMETERS AND USES THEREOF | Avalyn Pharma Inc. | PINDERSKI, JACQUELINE M | 3785 | §103§112 | Final Rejection | 104d overdue | Pending | Feb 21, 2023 |
| 18111511 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | Servier Pharmaceuticals LLC | KOMATSU, LI N | 1658 | DP | Non-Final OA | — | Pending | Feb 17, 2023 |
| 18042193 | A METHOD FOR THE ISOLATION OF DOUBLE-STRAND BREAKS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD | RYAN, DOUGLAS CHARLES | 1635 | §101§102§103§112Other | Final Rejection | 3d overdue | Pending | Feb 17, 2023 |
| 18040933 | STABLE CELL LINES FOR SITE-SPECIFIC INCORPORATION OF UNNATURAL AMINO ACIDS | Brickbio, Inc. | POPA, ILEANA | 1633 | §103§112Other | Non-Final OA | — | Pending | Feb 07, 2023 |
| 18106443 | SUBSTRATES, SYSTEMS, AND METHODS FOR NUCLEIC ACID ARRAY SYNTHESIS | Vibrant Holdings, LLC | BUNKER, AMY M | 1684 | §103 | Final Rejection | — | Pending | Feb 06, 2023 |
| 18040383 | LOW MOLECULAR WEIGHT PROTEIN DEGRADERS AND THEIR APPLICATIONS | Captor Therapeutics S.A. | TRAN, SUSAN T | 1615 | §102§103§112 | Final Rejection | — | Pending | Feb 02, 2023 |
| 18163451 | MACHINE LEARNING TECHNIQUES FOR DISCOVERING ERRORS AND SYSTEM READINESS CONDITIONS IN LIQUID CHROMATOGRAPHY INSTRUMENTS | Waters Technologies Ireland Limited | HAMMOND III, THOMAS M | 2855 | §101§102§103§112Other | Non-Final OA | 70d | Pending | Feb 02, 2023 |
| 18163196 | CAPTURE OF NUCLEIC ACIDS USING A NUCLEIC ACID-GUIDED NUCLEASE-BASED SYSTEM | Jumpcode Genomics, Inc. | BERTAGNA, ANGELA MARIE | 1681 | §103§112 | Non-Final OA | — | Pending | Feb 01, 2023 |
| 18160724 | EVENT DETECTION FOR DRUG DELIVERY SYSTEM | Insulet Corporation | GOLLAMUDI, NEERAJA | 3783 | §102§103§112 | Non-Final OA | — | Pending | Jan 27, 2023 |
| 18159300 | ACCELERATOR FOR MULTI-PASS MASS SPECTROMETERS | Micromass UK Limited | LOGIE, MICHAEL J | 2881 | §103DP | Non-Final OA | — | Pending | Jan 25, 2023 |
| 18157394 | METHODS AND SYSTEMS FOR PRESSURE-BASED FLUID CONTROL IN A FLUID DELIVERY SYSTEM | Insulet Corporation | NORTH, ISABELLA SARAH HYO SO | 3783 | §103§112 | Final Rejection | 4d overdue | Pending | Jan 20, 2023 |
| 18156687 | Pain Medicine Combination and Uses Thereof | Mindlab, LLC | CHONG, YONG SOO | 1623 | §103 | Final Rejection | — | Pending | Jan 19, 2023 |
| 18016827 | ORTHOPAEDIC JOINT DEVICE | Otto Bock Healthcare Products GmbH | BAHENA, CHRISTIE L. | 3774 | §102§103§112 | Non-Final OA | 21d | Pending | Jan 18, 2023 |
| 18016838 | METHOD FOR CONTROLLING A PROSTHESIS OR ORTHOSIS | Otto Bock Healthcare Products GmbH | BAHENA, CHRISTIE L. | 3774 | §103 | Final Rejection | 35d overdue | Pending | Jan 18, 2023 |
| 18014862 | INFUSION PUMP DEPLOYMENT SYSTEMS AND METHODS | Insulet Corporation | PONTON, JAMES D | 3783 | §102§103§112 | Non-Final OA | — | Pending | Jan 06, 2023 |
| 18004589 | FILTRATION ASSEMBLIES, CASSETTES, SYSTEMS, AND METHODS FOR FILTRATION AND CELL GROWTH | Rapid Micro Biosystems, Inc. | SHI, TINGCHEN | 1796 | §103 | Non-Final OA | 61d | Pending | Jan 06, 2023 |
| 18004151 | COMPOSITIONS AND METHODS FOR CELLULAR REPROGRAMMING USING CIRCULAR RNA | Elevatebio Technologies, Inc. | ROGERS, ERIC JASON | 1638 | §102§103§112DP | Final Rejection | 7d | Pending | Jan 03, 2023 |
| 18092544 | POLYPEPTIDES, VACCINE COMPOSITIONS, AND USE THEREOF FOR INDUCING IMMUNE RESPONSE TO SARS-COV-2 IN PRIMATES | Kang Zhang | QIAN, CELINE X | 1637 | §102§103§112 | Non-Final OA | — | Pending | Jan 03, 2023 |
| 18003234 | RECOMBINANT SIALIDASES WITH REDUCED PROTEASE SENSITIVITY, SIALIDASE FUSION PROTEINS, AND METHODS OF USING THE SAME | Palleon Pharmaceuticals Inc. | GODDARD, LAURA B | 1642 | §102§112DP | Non-Final OA | — | Pending | Dec 23, 2022 |
| 18145772 | SARS-COV-2 SERUM ANTIBODY PROFILING | Serimmune Inc. | ZOU, NIANXIANG | 1671 | §102§103§112 | Non-Final OA | 162d overdue | Pending | Dec 22, 2022 |
| 18085792 | THERAPEUTIC COMPOSITIONS, COMBINATIONS, AND METHODS OF USE | Verastem, Inc. | JAVANMARD, SAHAR | 1622 | §103§112Other | Final Rejection | 142d overdue | Pending | Dec 21, 2022 |
| 18001898 | PARALLEL ANALYSIS OF INDIVIDUAL CELLS FOR RNA EXPRESSION AND DNA FROM TARGETED TAGMENTATION BY SEQUENCING | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD | PHAM, KHAI QUYNH TIEN | 1684 | §103 | Non-Final OA | — | Pending | Dec 15, 2022 |
| 18078269 | RAF KINASE INHIBITORS AND METHODS OF USE THEREOF | Deciphera Pharmaceuticals, LLC | ENGLISH, CONNOR KENNEDY | 1625 | §103 | Final Rejection | 8d overdue | Pending | Dec 09, 2022 |
| 18009612 | SYSTEMS AND DEVICES FOR CONTROLLED DRUG DELIVERY | BEXSON BIOMEDICAL, INC. | PONTON, JAMES D | 3783 | §102§103§112 | Non-Final OA | 35d | Pending | Dec 09, 2022 |
| 18078240 | INTERTUMORAL HOMOGENEITY DETERMINED BY MiCK ASSAY | Pierian Biosciences, LLC | BAEK, JONGHWAN NMN | 1618 | §101§103§112Other | Non-Final OA | 6d | Pending | Dec 09, 2022 |
| 18074202 | METHODS AND ARRANGEMENTS FOR LIMIT ANALYSIS AND OPTIMIZATION | State Street Bank And Trust Company | HOANG, AMY P | 2143 | §103 | Final Rejection | — | Pending | Dec 02, 2022 |
| 17928708 | TREATMENT OF NEUROLOGICAL DISEASES USING MODULATORS OF GENE TRANSCRIPTS | Quralis Corporation | SHIN, DANA H | 1635 | §112 | Final Rejection | 80d overdue | Pending | Nov 30, 2022 |
| 18059170 | CAPACITANCE SENSING FOR COMPONENT POSITIONING DETECTION | Insulet Corporation | BOBISH, CHRISTOPHER S | 3746 | §103 | Final Rejection | 16d | Pending | Nov 28, 2022 |
| 17923421 | ENPP1 INHIBITORS AND METHODS OF MODULATING IMMUNE RESPONSE | Angarus Therapeutics, Inc. | JARRELL, NOBLE E | 1699 | §112 | Final Rejection | 86d overdue | Pending | Nov 22, 2022 |
| 17989006 | METHODS AND COMPOSITIONS FOR TREATING ABNORMAL CELL GROWTH | Verastem, Inc. | JAVANMARD, SAHAR | 1622 | §103§112DP | Final Rejection | — | Pending | Nov 17, 2022 |
| 17998012 | AN ATMOSPHERIC PRESSURE IONISATION SOURCE | Micromass UK Ltd. | KALISZEWSKI, ALINA ROSE | 2881 | §103 | Non-Final OA | — | Pending | Nov 04, 2022 |
| 17921509 | METHODS OF TREATING ABNORMAL CELL GROWTH | Verastem, Inc. | HIRAKIS, SOPHIA P | 1623 | §103 | Non-Final OA | — | Pending | Oct 26, 2022 |
| 17921257 | METHODS FOR SYNTHESIZING N-(PHENYLSULFONYL)BENZAMIDE COMPOUNDS AND INTERMEDIATES THEREOF | Ascentage Pharma Group Corp Limited | HEITMEIER, KENDALL NICOLE | 1621 | §102 | Final Rejection | 2d overdue | Pending | Oct 25, 2022 |
| 18048747 | DUAL TARGETED IMMUNE REGULATING COMPOSITIONS | Seismic Therapeutic, Inc. | MOSELEY II, NELSON B | 1642 | §103DP | Non-Final OA | — | Pending | Oct 21, 2022 |
| 17996599 | CALIBRATION OF ANALYTICAL INSTRUMENT | Micromass UK Limited | STOFFA, WYATT A | 2800 | §101§102 | Non-Final OA | — | Pending | Oct 19, 2022 |
| 17995657 | SYSTEM FOR DELIVERING TARGETED CONTENT WITH CARE PREFERENCE SUGGESTIONS | Texas Medical Center | KANAAN, LIZA TONY | 3683 | §101§103§112 | Non-Final OA | — | Pending | Oct 06, 2022 |
| 17995098 | AN ELECTRIC FIELD OR ELECTRIC VOLTAGE DELIVERING ELECTRODE SYSTEM FOR THE TREATMENT OF INTERNAL ORGAN OEDEMA | Berlin Heals GmbH | SIRCAR, ALISHA JITENDRA | 3792 | §112 | Non-Final OA | — | Pending | Sep 29, 2022 |
| 17954969 | GRAPH BASED MACHINE LEARNING FOR GENERATING VALID SMALL MOLECULE COMPOUNDS | Chengdu Anticancer Bioscience, Ltd. | HILL, GRACELYN MARKHAM | 1685 | §101§103§112 | Non-Final OA | 35d | Pending | Sep 28, 2022 |
| 17914691 | METHODS OF USING UMBILICAL CORD PRODUCTS FOR TREATMENT OF OCULAR SURFACE DISORDERS | BIOTISSUE HOLDINGS INC. | MOSS, NATALIE M | 1653 | §103 | Non-Final OA | — | Pending | Sep 26, 2022 |
| 17934950 | PROCESS FOR PREPARATION OF STABLE PROTEIN SOLUTION | Kashiv Biosciences, LLC | COOK, LISA V | 1642 | §112Other | Non-Final OA | 59d overdue | Pending | Sep 23, 2022 |
| 17932845 | METHODS, MEDIUMS, AND SYSTEMS FOR ESTABLISHING A QUALITY CONTROL RECORD CHAIN FOR LABORATORY ANALYTICAL INSTRUMENTS | Waters Technologies Ireland Limited | LESNIEWSKI, VICTOR D | 2493 | §103 | Final Rejection | 26d | Pending | Sep 16, 2022 |
| 17821989 | COMPENSATING FOR CHANGES IN POTENCY OF A MEDICAMENT IN A MEDICAMENT DELIVERY DEVICE | Insulet Corporation | BOSWORTH, KAMI A | 3783 | §112 | Final Rejection | — | Pending | Aug 24, 2022 |
| 17800958 | METHODS AND COMPOSITIONS FOR MODULATING ARGININE LEVELS IN IMMUNE CELLS | Sky Perfect International Limited | DHAR, MATASHA | 1632 | §101§102§103§112 | Final Rejection | 147d overdue | Pending | Aug 19, 2022 |
| 17904089 | ENGINEERED FLUORESCENT SPONTANEOUS ISOMERIZATION RATE BIOSENSORS | Calico Life Sciences LLC | TRAN, CHAU NGUYEN BICH | 1677 | §102§103Other | Final Rejection | — | Pending | Aug 11, 2022 |
| 17904038 | BIO-THERAPEUTICS FOR DETECTION, DIAGNOSIS AND TREATMENT OF DISEASES ASSOCIATED WITH MUCOSAL BLEEDING | Tenza, Inc. | JOHANSEN, PETER N. | 1644 | §102§103§112 | Non-Final OA | 21d | Pending | Aug 11, 2022 |
| 17817312 | HIV ANTIGENS AND MHC COMPLEXES | Gritstone Bio, Inc. | LIPPOLIS, ALEXANDRA ROSE | 1637 | §103§112 | Non-Final OA | — | Pending | Aug 03, 2022 |
| 17879923 | 6-MEMBERED AZA-HETEROCYCLIC CONTAINING DELTA-OPIOID RECEPTOR MODULATING COMPOUNDS, METHODS OF USING AND MAKING THE SAME | Trevena, Inc. | JAVANMARD, SAHAR | 1622 | §102§103Other | Final Rejection | 147d overdue | Pending | Aug 03, 2022 |
| 17815928 | SAFE HARBOR LOCI | Bit Bio Limited | BRETZ, COREY LANE | 1600 | §103 | Final Rejection | — | Pending | Jul 28, 2022 |
| 17759681 | COMBINATIONS OF EGFR INHIBITORS AND ROR1 INHIBITORS FOR THE TREATMENT OF CANCER | Ho'Ola Therapeutics Inc. | CHASE, CAROL ANN | 1646 | §103 | Non-Final OA | — | Pending | Jul 28, 2022 |
| 17845275 | USE OF 1-[4-BROMO-5-[1-ETHYL-7-(METHYLAMINO)-2-OXO-1,2-DIHYDRO-1,6-NAPHTHYRIDIN-3-YL]-2-FLUOROPHENYL]-3-PHENYLUREA AND ANALOGS FOR THE TREATMENT OF CANCERS ASSOCIATED WITH GENETIC ABNORMALITIES IN PLATELET DERIVED GROWTH FACTOR RECEPTOR ALPHA | Deciphera Pharmaceuticals, LLC | RODRIGUEZ, RAYNA B | 1628 | §103§112 | Final Rejection | 12d | Pending | Jun 21, 2022 |
| 17843167 | METHODS, MEDIUMS, AND SYSTEMS FOR PREDICTING MOLECULE MODIFICATIONS | Waters Technologies Ireland Limited | REYES, REGINALD R | 3684 | §101Other | Final Rejection | — | Pending | Jun 17, 2022 |
| 17785385 | METHODS, KITS AND COMPOSITIONS FOR REDUCING CARDIOTOXICITY ASSOCIATED WITH CANCER THERAPIES | Richard G. Pestell | DENT, ALANA HARRIS | 1643 | §102§103§112 | Final Rejection | 53d overdue | Pending | Jun 14, 2022 |
| 17839786 | NON-NANOPARTICULATE APPLICATION FORMS OF MACROLIDES | Nucleus Medical GmbH | LEE, SIN J | 1613 | §103 | Non-Final OA | 58d overdue | Pending | Jun 14, 2022 |
| 17839647 | METHOD FOR MODIFICATION OF MAXIMUM DELIVERY LIMITS IN AUTOMATIC DRUG DELIVERY SYSTEMS | Insulet Corporation | PRICE, NATHAN R | 3783 | §101§102§112 | Final Rejection | — | Pending | Jun 14, 2022 |
| 17839645 | HYBRID INJECTION-PUMP INSULIN DELIVERY | Insulet Corporation | PRICE, NATHAN R | 3783 | §103§112 | Final Rejection | — | Pending | Jun 14, 2022 |
| 17838114 | DURABLE VACCINATION | Gritstone Bio, Inc. | CHEN, STACY BROWN | 1672 | §103§112DP | Final Rejection | — | Pending | Jun 10, 2022 |
| 17782239 | Systems and Methods for Measuring Concentration of an Analyte | Brolis Sensor Technology, Uab | SMITH, EMILIE ALINE | 1686 | §101§103 | Non-Final OA | — | Pending | Jun 03, 2022 |
| 17749449 | METHODS, MEDIUMS, AND SYSTEMS FOR PROVIDING ASSISTED CALIBRATION FOR A MASS SPECTROMETRY APPARATUS | Waters Technologies Ireland Limited | OSENBAUGH-STEWART, ELIZA W | 2881 | §103 | Final Rejection | 34d | Pending | May 20, 2022 |
| 17744354 | ANTIGEN-BINDING PROTEINS TARGETING SHARED NEOANTIGENS | Gritstone Bio, Inc. | LEE, YIE CHIA | 1642 | §101§102§103§112 | Non-Final OA | — | Pending | May 13, 2022 |
| 17742998 | METHODS AND DEVICES FOR DETERMINING FLUID DELIVERY PUMP INFORMATION | Insulet Corporation | SMALE, AVERY E | 3783 | §103 | Final Rejection | — | Pending | May 12, 2022 |
| 17736738 | SHARED NEOANTIGEN VACCINES | Gritstone Bio, Inc. | VIVLEMORE, TRACY ANN | 1638 | §102Other | Final Rejection | 141d overdue | Pending | May 04, 2022 |
| 17736380 | USING MACRONUTRIENT INFORMATION TO OPTIMIZE INSULIN DOSING | Insulet Corporation | STANEK, KELSEY L | 3741 | §103 | Non-Final OA | — | Pending | May 04, 2022 |
| 17724876 | GARMENT FOR TREATMENT OF INCONTINENCE | Attn: Grace, Inc. | HAN, SETH | 3781 | §103 | Non-Final OA | 4d overdue | Pending | Apr 20, 2022 |
| 17718663 | COMPENSATION FOR CALIBRATION OFFSETS IN AGENT DELIVERY DEVICES | Insulet Corporation | KOO, BENJAMIN K | 3783 | §103 | Final Rejection | — | Pending | Apr 12, 2022 |
| 17768146 | MODIFIED STEM CELLS AND METHODS OF USE THEREOF | Arizona Board of Regents | PENNINGTON, KATIE LEIGH | 1634 | §102§103§112 | Non-Final OA | — | Pending | Apr 11, 2022 |
| 17658817 | SURGICAL FASTENERS, TOOLS, AND METHODS | Arthrosurface, Inc. | RAMANA, ANURADHA | 3775 | §102§103Other | Non-Final OA | — | Pending | Apr 11, 2022 |
| 17767687 | Chimeric Cytokine Receptors | UVIC INDUSTRY PARTNERSHIPS INC. | GRABER, JAMES J | 1631 | §103DP | Final Rejection | 26d | Pending | Apr 08, 2022 |
| 17766439 | IMAGING SYSTEM AND METHOD OF USE THEREOF | New York Stem Cell Foundation, Inc. | PARK, EDWARD | 2675 | §101§103 | Non-Final OA | 33d | Pending | Apr 04, 2022 |
| 17639401 | METHODS OF TREATING EPILEPSY USING THE SAME | Trevena, Inc. | NESTOR, DONNA MICHELLE | 1627 | §103DPOther | Non-Final OA | 60d | Pending | Mar 01, 2022 |
| 17674093 | DRIVE MECHANISMS FOR POSITIVE DISPLACEMENT PUMPS | Insulet Corporation | DESANTO, MATTHEW F | 3700 | §102 | Non-Final OA | — | Pending | Feb 17, 2022 |
| 17635751 | ORTHOPAEDIC DEVICE AND ENERGY STORAGE DEVICE | Ottobock SE & Co. Kgaa | DUDDEN, TERESA MARIE | 3774 | §103§112 | Final Rejection | 23d overdue | Pending | Feb 16, 2022 |
| 17669766 | COMPOSITIONS AND METHODS OF THEIR USE | Synedgen, Inc. | BAKSHI, PANCHAM | 1623 | §103DP | Non-Final OA | — | Pending | Feb 11, 2022 |
| 17668124 | INTEGRATION OF SENSORS FOR DRUG DELIVERY COMPENSATION IN AUTOMATED MEDICATION DELIVERY (AMD) SYSTEMS | Insulet Corporation | TAYLOR, MARISSA ENVENESIA | 3783 | §103§112 | Non-Final OA | — | Pending | Feb 09, 2022 |
| 17665165 | TECHNIQUES AND DEVICES FOR ADAPTATION OF MAXIMUM DRUG DELIVERY LIMITS | Insulet Corporation | DIOP, FATIMATA SAHRA | 3783 | §103 | Final Rejection | — | Pending | Feb 04, 2022 |
| 17586238 | ULINASTATIN POLYPEPTIDES FOR TREATING DISEASES | Diamedica Usa Inc. | HADDAD, MAHER M | 1641 | DP | Non-Final OA | 35d overdue | Pending | Jan 27, 2022 |
| 17581788 | NEOANTIGEN IDENTIFICATION USING HOTSPOTS | Gritstone Bio, Inc. | WOITACH, JOSEPH T | 1687 | §101§112Other | Non-Final OA | — | Pending | Jan 21, 2022 |
| 17580249 | CONDUCTIVE ELEMENT IN ADHESIVE PATCH OF ON-BODY DRUG DELIVERY DEVICE FOR BODY CHANNEL COMMUNICATION | Insulet Corporation | GOLLAMUDI, NEERAJA | 3783 | §103 | Final Rejection | — | Pending | Jan 20, 2022 |
| 17627477 | PROCESS FOR SEPARATION AND QUANTITATION OF PROTEINS USING CAPILLARY ELECTROPHORESIS | Kashiv Biosciences, LLC | OSMAN, SOMMER YOUSEF | 1794 | §103§112 | Non-Final OA | — | Pending | Jan 14, 2022 |
| 17574790 | Methods and Compositions for Two-Stage Microbubble Delivery of Active Agents | VIRGINIA COMMONWEALTH UNIVERSITY | SCHLIENTZ, LEAH H | 1618 | §103 | Non-Final OA | 12d | Pending | Jan 13, 2022 |
| 17624121 | RECOMBINANT HUMAN SIALIDASES, SIALIDASE FUSION PROTEINS, AND METHODS OF USING THE SAME | Palleon Pharmaceuticals Inc. | BORGEEST, CHRISTINA M | 1675 | §102§112 | Non-Final OA | 51d overdue | Pending | Dec 30, 2021 |
| 17559013 | METHODS, MEDIUMS, AND SYSTEMS FOR STORING AND RETRIEVING CHROMATOGRAPHY DATA | Waters Technologies Ireland Limited | HYUN, PAUL SANG HWA | 1796 | §112 | Final Rejection | 5d | Pending | Dec 22, 2021 |
| 17554514 | INTEGRATION OF A MEDICAMENT DELIVERY DEVICE WITH A SMARTWATCH AND A VEHICLE INFOTAINMENT SYSTEM | Insulet Corporation | PONTON, JAMES D | 3783 | §103 | Non-Final OA | — | Pending | Dec 17, 2021 |
| 17620650 | METHODS OF PROMOTING VASCULOGENESIS | BIOTISSUE HOLDINGS INC. | JOHNSON, ALLISON MARIE | 1638 | §112 | Non-Final OA | — | Pending | Dec 17, 2021 |
| 17552935 | METHODS, MEDIUMS, AND SYSTEMS FOR BUILDING AND EXECUTING A CHROMATOGRAPHY WORKFLOW | Waters Technologies Ireland Limited | GAVIN, KRISTIN ELIZABETH | 3624 | §101§112 | Final Rejection | 99d overdue | Pending | Dec 16, 2021 |
| 17619036 | COMPOSITIONS AND METHODS FOR BIOLOGICAL DELIVERY VEHICLES | Dnalite Therapeutics, Inc. | MITCHELL, EDWIN COLEMAN | 1619 | §103§112 | Final Rejection | 89d overdue | Pending | Dec 14, 2021 |
| 17616350 | OLIGONUCLEOTIDES AND METHODS OF USE FOR TREATING NEUROLOGICAL DISEASES | Quralis Corporation | RAVINDRA, KRISHNA NUGGEHALLI | 1636 | §103 | Final Rejection | — | Pending | Dec 03, 2021 |
| 17613927 | RAPID AND DETERMINISTIC GENERATION OF MICROGLIA FROM HUMAN PLURIPOTENT STEM CELLS | Westfälische Wilhelms-Universität Münster | BATES, KEENAN ALEXANDER | 1631 | §103 | Final Rejection | — | Pending | Nov 23, 2021 |
| 17508556 | METHODS AND ARRANGEMENTS TO MANAGE REQUIREMENTS AND CONTROLS, AND DATA AT THE INTERSECTION THEREOF | State Street Corporation | BADAWI, ANGIE M | 2179 | §103 | Non-Final OA | 7d | Pending | Oct 22, 2021 |
| 17505883 | TECHNIQUES AND INSULIN PUMP FOR ENHANCED SITE HEALTH AND BLOOD GLUCOSE CONTROL FOR AID SYSTEMS | Insulet Corporation | GONG, KRIS HANYU | 3785 | §103 | Final Rejection | — | Pending | Oct 20, 2021 |
| 17506145 | BODY CONFORMING WEARABLE DEVICE FOR PROVIDING OUTPUT AND INPUT FOR A DRUG DELIVERY SYSTEM | Insulet Corporation | RODRIGUEZ, CRIS LOIREN | 3783 | §102§103 | Final Rejection | 7d | Pending | Oct 20, 2021 |
| 17440067 | PEPTIDE-INDUCED NK CELL ACTIVATION | UNIVERSITY OF SOUTHAMPTON | DICKINSON, PAUL W | 1618 | §103§112 | Non-Final OA | 27d | Pending | Sep 16, 2021 |
| 17436367 | IDENTIFICATION OF NEOANTIGENS WITH MHC CLASS II MODEL | Gritstone Bio, Inc. | NGUYEN, PETER | 1685 | §101§103DP | Final Rejection | — | Pending | Sep 03, 2021 |
| 17446807 | PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY | AbbVie Inc. | SHTERENGARTS, SAMANTHA L | 1623 | §112 | Non-Final OA | — | Pending | Sep 02, 2021 |
| 17412684 | SYSTEMS AND METHODS FOR ACTIVATING DRUG DELIVERY DEVICES | Insulet Corporation | VU, QUYNH-NHU HOANG | 3783 | §103 | Final Rejection | 29d | Pending | Aug 26, 2021 |
| 17446084 | REMOTE MANAGEMENT OF A MEDICAMENT DELIVERY DEVICE USING DATA ANALYTICS | Insulet Corporation | VANDER WOUDE, KIMBERLY ELAINE | 3681 | §101§103§112 | Non-Final OA | — | Pending | Aug 26, 2021 |
| 17433817 | SELECTION OF T CELL RECEPTORS | Gritstone Bio, Inc. | FAUST, AMBER KATHLEEN | 1643 | §103 | Final Rejection | — | Pending | Aug 25, 2021 |
| 17426141 | SURVIVAL-TARGETING CHIMERIC (SURTAC) MOLECULES | Entact Bio Limited | YAO, LEI | 1642 | §112 | Non-Final OA | 3d overdue | Pending | Jul 28, 2021 |
| 17420833 | TREATMENT OF CANCER HAVING GNAQ OR GNA11 GENETIC MUTATIONS WITH PROTEIN KINASE C INHIBITORS | Ideaya Biosciences, Inc. | YOO, SUN JAE | 1621 | — | Non-Final OA | — | Pending | Jul 06, 2021 |
| 17295782 | COMPOSITIONS AND METHODS FOR INCREASING FETAL HEMOGLOBIN AND TREATING SICKLE CELL DISEASE | Fulcrum Therapeutics, Inc. | EBBINGHAUS, BRIANA NOEL | 1632 | §112 | Non-Final OA | — | Pending | May 20, 2021 |
| 17291070 | METHODS OF CELLULAR REPROGRAMMING | BIOTISSUE HOLDINGS INC. | BATES, KEENAN ALEXANDER | 1631 | §103§112 | Non-Final OA | — | Pending | May 04, 2021 |
| 17271045 | METHODS FOR REDUCING THE RISK OF DIABETES IN PATIENTS BEING TREATED FOR HIGH CHOLESTEROL-RELATED ILLNESSES | Esperion Therapeutics, Inc. | HUTTER, GILLIAN A | 1625 | §102 | Non-Final OA | 57d | Pending | Feb 24, 2021 |
| 17157043 | Dynamically Changing Promotions Displayed on a Mobile Device and Measuring The Benefit Thereof | UPSIDE SERVICES, INC. | OSMAN BILAL AHMED, AFAF | 3622 | §101§103 | Final Rejection | 147d overdue | Pending | Jan 25, 2021 |
| 17150372 | INTELLIGENT SITUATIONAL ALARMS AND NOTIFICATIONS FOR DIABETES MANAGEMENT DEVICES | Insulet Corporation | COBANOGLU, DILEK B | 3687 | §101§102 | Non-Final OA | — | Pending | Jan 15, 2021 |
| 17150461 | MEAL INSULIN DETERMINATION FOR IMPROVED POST PRANDIAL RESPONSE | Insulet Corporation | BARTLEY, KENNETH | 3684 | §103§112 | Non-Final OA | 4d overdue | Pending | Jan 15, 2021 |
| 17058128 | SHARED ANTIGENS | Gritstone Oncology, Inc. | MCLEOD, AFRICA MHAIRIE | 1600 | §102§103DP | Non-Final OA | — | Pending | Nov 23, 2020 |
| 16952231 | SYSTEMS AND METHODS FOR ANALYSIS OF ALTERNATIVE SPLICING | Envisagenics, Inc. | VASSELL, MEREDITH ABBOTT | 1687 | §103§112 | Final Rejection | — | Pending | Nov 19, 2020 |
| 17096565 | ADAPTIVE DURATION OF INSULIN ACTION FOR USE IN INSULIN ON BOARD CALCULATIONS | Insulet Corporation | JANG, CHRISTIAN Y | 3791 | §112 | Non-Final OA | — | Pending | Nov 12, 2020 |
| 17054400 | ARTIFICIAL FOOT | Ottobock SE & Co. Kgaa | SPENCER, MAXIMILIAN TOBIAS | 3774 | §103 | Non-Final OA | — | Pending | Nov 10, 2020 |
| 17085344 | SYSTEMS AND METHODS FOR DETERMINING PLACEMENT OF WEARABLE DRUG DELIVERY DEVICES | Insulet Corporation | TRINH, HONG-VAN N | 3783 | §102§103 | Non-Final OA | — | Pending | Oct 30, 2020 |
| 17028595 | INHALED IMATINIB FOR TREATMENT OF PULMONARY ARTERIAL HYPERTENSION (PAH) | Avalyn Pharma Inc. | HAGHIGHATIAN, MINA | 1616 | §103§112 | Final Rejection | 45d overdue | Pending | Sep 22, 2020 |
| 17008101 | ADJUSTING SETTINGS TO DIFFERENT DEGREES OF AGGRESSIVENESS IN AN AUTOMATED INSULIN DELIVERY SYSTEM BASED ON QUALITY OF BLOOD GLUCOSE LEVEL CONTROL BY A USER | Insulet Corporation | KRETZER, KYLE W. | 3791 | §103 | Final Rejection | 12d | Pending | Aug 31, 2020 |
| 16975823 | Neoantigen Identification with Pan-Allele Models | Gritstone Bio,Inc. | BAILEY, STEVEN WILLIAM | 1687 | §101§103§112DP | Final Rejection | 45d overdue | Pending | Aug 26, 2020 |
| 16995527 | RATCHET DRIVE FOR ON BODY DELIVERY SYSTEM | Insulet Corporation | SWANSON, LEAH JENNINGS | 3783 | §103§112 | Final Rejection | 14d | Pending | Aug 17, 2020 |
| 16859544 | FILLING ASSIST MECHANISMS AND KEYED INTERFACES FOR DRUG DELIVERY DEVICES | Insulet Corporation | SWANSON, LEAH JENNINGS | 3783 | §102§103 | Final Rejection | 3d overdue | Pending | Apr 27, 2020 |
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